Revista Colombiana de Reumatologia最新文献

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Interstitial lung disease in primary Sjögren's syndrome 原发性斯约格伦综合征的间质性肺病
Revista Colombiana de Reumatologia Pub Date : 2024-04-01 DOI: 10.1016/j.rcreu.2023.10.004
Santiago Auteri , Anastasia Secco
{"title":"Interstitial lung disease in primary Sjögren's syndrome","authors":"Santiago Auteri ,&nbsp;Anastasia Secco","doi":"10.1016/j.rcreu.2023.10.004","DOIUrl":"10.1016/j.rcreu.2023.10.004","url":null,"abstract":"<div><p>Interstitial lung disease is a common complication of Sjögren's syndrome that can occur at diagnosis or during follow-up. To detect it, complete pulmonary function studies should be performed, including spirometry, measurement of lung volumes, and DLCO, with the latter being the most sensitive parameter for detecting the presence of the disease. High-resolution computed tomography is essential for the study. Sixty percent of patients present a single tomographic pattern, with non-specific interstitial pneumonia being the most frequent pattern, followed by usual interstitial pneumonia pattern. Mortality is high, being higher in those with lower forced vital capacity, lower DLCO, and higher fibrosis score on chest computed tomography. Currently, there are two international guidelines for the treatment of pulmonary manifestations of Sjögren, but recommendations are based on low-quality scientific evidence. A stepwise approach is suggested, initially with glucocorticoids, then immunosuppressants, and in refractory or severe cases, considering other agents such as rituximab. The use of antifibrotic medication is recommended in patients who develop progressive pulmonary fibrosis as defined by current criteria. It is important to bear in mind that although non-specific interstitial pneumonia is considered a pattern where inflammation predominates, there may be progression to progressive pulmonary fibrosis in some cases. Lung transplantation and oxygen therapy may be options for selected patients. The relevance of an interdisciplinary team approach to achieve adequate diagnosis and treatment of patients is highlighted.</p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139188333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Screening, diagnosis, and monitoring of interstitial lung disease in autoimmune rheumatic diseases: A narrative review 自身免疫性风湿病中间质性肺疾病的筛查、诊断和监测:综述
Revista Colombiana de Reumatologia Pub Date : 2024-04-01 DOI: 10.1016/j.rcreu.2023.06.002
Samuel D. Good , Jeffrey A. Sparks , Elizabeth R. Volkmann
{"title":"Screening, diagnosis, and monitoring of interstitial lung disease in autoimmune rheumatic diseases: A narrative review","authors":"Samuel D. Good ,&nbsp;Jeffrey A. Sparks ,&nbsp;Elizabeth R. Volkmann","doi":"10.1016/j.rcreu.2023.06.002","DOIUrl":"10.1016/j.rcreu.2023.06.002","url":null,"abstract":"<div><p>Interstitial lung disease (ILD) is a common and serious manifestation of autoimmune rheumatic diseases. While the prevalence of ILD differs among the individual autoimmune rheumatic diseases, ILD remains an important cause of morbidity and mortality in systemic sclerosis, systemic lupus erythematosus, mixed connective tissue disease, primary Sjögren's disease, rheumatoid arthritis, and idiopathic inflammatory myositis. The present review summarizes recent literature on autoimmune-associated ILD with a focus on screening and monitoring for ILD progression. Reflecting on the currently available evidence, the authors propose a guideline for monitoring for progression in patients with newly diagnosed autoimmune-associated ILD. This review also highlights clinical and biological predictors of progressive pulmonary fibrosis and describes opportunity for further study in the rapidly evolving area of rheumatology and pulmonology.</p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41446092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sequential approach to interstitial lung disease: An autoimmune perspective 间质性肺病的序列方法:从自身免疫角度看间质性肺病
Revista Colombiana de Reumatologia Pub Date : 2024-04-01 DOI: 10.1016/j.rcreu.2023.10.002
Camila Borda Samper , Néstor Fabián Correa-González , Carlos Andrés Celis Preciado , Santiago Bernal-Macías , Juan Sebastián Sierra , Daniel G. Fernández-Ávila
{"title":"Sequential approach to interstitial lung disease: An autoimmune perspective","authors":"Camila Borda Samper ,&nbsp;Néstor Fabián Correa-González ,&nbsp;Carlos Andrés Celis Preciado ,&nbsp;Santiago Bernal-Macías ,&nbsp;Juan Sebastián Sierra ,&nbsp;Daniel G. Fernández-Ávila","doi":"10.1016/j.rcreu.2023.10.002","DOIUrl":"10.1016/j.rcreu.2023.10.002","url":null,"abstract":"<div><p>Interstitial lung disease occurs with high frequency as an initial or late manifestation of multiple rheumatic diseases, including systemic sclerosis, idiopathic inflammatory myopathies, rheumatoid arthritis, systemic lupus erythematosus, primary Sjögren's syndrome and antineutrophil cytoplasmic antibody-associated vasculitis. Thus, the rheumatologist must be clear about certain concepts of pneumology, including the evaluation of lung function tests, the approach to radiological patterns observed on high-resolution computed tomography of the chest, and concepts such as interstitial pneumonia with autoimmune features. In this article, we present our approach to patients with interstitial lung disease, in whom an autoimmune etiology is suspected. We propose a sequential diagnostic strategy, recognizing the importance of the multidisciplinary team and including the autoimmune perspective with emphasis on clinical and serological domains. Other diagnostic tools such as capillaroscopy and minor salivary gland biopsy are also considered. We also take a critical look at the latest guidelines for progressive pulmonary fibrosis, since it is essential that the rheumatologist understands these concepts that are vital in a multidisciplinary team.</p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139191811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The treatment of interstitial lung disease (ILD) in the context of autoimmune diseases: Rheumatoid arthritis and idiopathic inflammatory myositis 治疗自身免疫性疾病中的间质性肺病(ILD):类风湿性关节炎和特发性炎症性肌炎
Revista Colombiana de Reumatologia Pub Date : 2024-04-01 DOI: 10.1016/j.rcreu.2023.07.004
Mayra Mejía , Daphne Rivero-Gallegos , Jorge Rojas-Serrano
{"title":"The treatment of interstitial lung disease (ILD) in the context of autoimmune diseases: Rheumatoid arthritis and idiopathic inflammatory myositis","authors":"Mayra Mejía ,&nbsp;Daphne Rivero-Gallegos ,&nbsp;Jorge Rojas-Serrano","doi":"10.1016/j.rcreu.2023.07.004","DOIUrl":"10.1016/j.rcreu.2023.07.004","url":null,"abstract":"<div><p><span>This article will mention the essential aspects of managing ILD<span><span><span> associated with systemic autoimmune diseases such as </span>rheumatoid arthritis (RA) and </span>inflammatory myopathies (IIM). The prognosis of rheumatoid arthritis-associated interstitial lung disease (RA-ILD) has recently improved because of tighter control of RA disease activity. This article presents recent evidence of the effect of </span></span>methotrexate<span> on RA-ILD, which is associated with a better prognosis. The available alternatives include the use of anti-fibrotic drugs. In managing interstitial lung disease related to anti-synthetase syndrome (ASSD-ILD) and anti-MDA5-associated ILD, immunosuppression and anti-fibrotic drug regimens are relevant aspects mentioned.</span></p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135515472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interstitial pneumonia with autoimmune features: Aiming to define, refine, and treat 具有自身免疫特征的间质性肺炎:旨在定义、完善和治疗
Revista Colombiana de Reumatologia Pub Date : 2024-04-01 DOI: 10.1016/j.rcreu.2023.07.006
Elena K. Joerns , Jeffrey A. Sparks
{"title":"Interstitial pneumonia with autoimmune features: Aiming to define, refine, and treat","authors":"Elena K. Joerns ,&nbsp;Jeffrey A. Sparks","doi":"10.1016/j.rcreu.2023.07.006","DOIUrl":"10.1016/j.rcreu.2023.07.006","url":null,"abstract":"<div><p>Interstitial pneumonia with autoimmune features (IPAF) was defined for research purposes as interstitial lung disease (ILD) associated with features of autoimmunity without diagnosed rheumatic disease (RD). Since publication of the IPAF criteria in 2015, there have been multiple studies of IPAF. However, much remains unknown regarding pathogenesis, prognosis, and treatment in IPAF. This narrative review details the history and classification of IPAF, lists challenges associated with classifying patients as IPAF, and explores the prevalence, epidemiology, and presentation of IPAF. We also examine prognosis and important features determining IPAF clinical course, outline pathogenesis, and review treatment strategies.</p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136009643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
La reumatología colombiana y el contexto latinoamericano 哥伦比亚风湿病与拉丁美洲背景
Revista Colombiana de Reumatologia Pub Date : 2024-04-01 DOI: 10.1016/j.rcreu.2023.03.004
Thalía Pinilla , Isabella Lacouture , Sofía de los Ángeles Acosta Rivas , Diego Rosselli
{"title":"La reumatología colombiana y el contexto latinoamericano","authors":"Thalía Pinilla ,&nbsp;Isabella Lacouture ,&nbsp;Sofía de los Ángeles Acosta Rivas ,&nbsp;Diego Rosselli","doi":"10.1016/j.rcreu.2023.03.004","DOIUrl":"10.1016/j.rcreu.2023.03.004","url":null,"abstract":"","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42377559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Guía de práctica clínica para la detección temprana, el diagnóstico, el tratamiento y el seguimiento de los pacientes con artritis reumatoide. Asociación Colombiana de Reumatología, 2022 类风湿关节炎患者早期发现、诊断、治疗和随访的临床实践指南。哥伦比亚风湿病协会,2022年
Revista Colombiana de Reumatologia Pub Date : 2024-04-01 DOI: 10.1016/j.rcreu.2023.02.001
Carlos Enrique Toro-Gutiérrez , Álvaro Arbeláez-Cortés , Andrés R. Fernández-Aldana , Rossana A. Mejía-Romero , Paul Méndez Patarroyo , Gerardo Quintana L. , Oscar O. Ruiz-Santacruz , Pedro Santos-Moreno , Daniel G. Fernández-Ávila
{"title":"Guía de práctica clínica para la detección temprana, el diagnóstico, el tratamiento y el seguimiento de los pacientes con artritis reumatoide. Asociación Colombiana de Reumatología, 2022","authors":"Carlos Enrique Toro-Gutiérrez ,&nbsp;Álvaro Arbeláez-Cortés ,&nbsp;Andrés R. Fernández-Aldana ,&nbsp;Rossana A. Mejía-Romero ,&nbsp;Paul Méndez Patarroyo ,&nbsp;Gerardo Quintana L. ,&nbsp;Oscar O. Ruiz-Santacruz ,&nbsp;Pedro Santos-Moreno ,&nbsp;Daniel G. Fernández-Ávila","doi":"10.1016/j.rcreu.2023.02.001","DOIUrl":"10.1016/j.rcreu.2023.02.001","url":null,"abstract":"<div><p>Clinical practice guideline 2022 for the early detection, diagnosis, treatment, and follow-up of patients with rheumatoid arthritis developed by the rheumatoid arthritis study group of the Colombian Association of Rheumatology. Rheumatoid arthritis (RA) is the most common autoimmune disease in adults. Worldwide, RA has a prevalence of .5%-1%, with an age-standardised prevalence rate of 246.6 per 100,000 population, being more common in women than in men and with peak presentation between the ages of 60 and 64 years. The disease is characterised by joint pain and inflammation and in some cases can cause extra-articular manifestations such as dry syndrome, vasculitis, pericarditis, pleuritis, scleritis, among others. RA causes great morbidity, impairment of quality of life, severe disability, high direct and indirect costs to health systems, disability, and absenteeism from work. This guideline was developed for rheumatologists, primary care physicians, specialists in related areas, and other actors in the system with the aim of providing the most relevant information on the early detection of the disease, and its correct diagnosis, treatment, and follow-up.</p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0121812323000154/pdfft?md5=eaa901219c55290d1ee30c5c08cd78a1&pid=1-s2.0-S0121812323000154-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44390893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Análisis de minimización de costos e impacto presupuestal de la viscosuplementación para el tratamiento de osteoartrosis de rodilla en El Salvador y Panamá 萨尔瓦多和巴拿马粘补治疗膝关节骨关节炎的成本最小化和预算影响分析
Revista Colombiana de Reumatologia Pub Date : 2024-04-01 DOI: 10.1016/j.rcreu.2022.09.002
Camilo Castañeda, Yaneth Gil Rojas
{"title":"Análisis de minimización de costos e impacto presupuestal de la viscosuplementación para el tratamiento de osteoartrosis de rodilla en El Salvador y Panamá","authors":"Camilo Castañeda,&nbsp;Yaneth Gil Rojas","doi":"10.1016/j.rcreu.2022.09.002","DOIUrl":"10.1016/j.rcreu.2022.09.002","url":null,"abstract":"<div><h3>Introduction/Objective</h3><p>To develop a cost minimization and a budget impact analysis of viscosupplementation with hylan G-F 20 1<!--> <!-->×<!--> <!-->6<!--> <!-->mL for the treatment of knee osteoarthrosis in patients who are not suitable for pharmacological treatment or surgery in El Salvador and Panama.</p></div><div><h3>Materials and methods</h3><p>The cost minimization and budget impact analyses were developed from the perspective of the public health system, with a 1-year and 5-year analysis horizon, respectively. The main parameters of the models were acquisition costs, administration, and the need for retreatment. For the budgetary impact, quantification of the population was based on published epidemiological information and local databases. Costs were reported in US dollars at 2020 prices.</p></div><div><h3>Results</h3><p>In El Salvador, the savings derived from its use were $ 35.0 (10%) vs. hylan G-F 20 (2<!--> <!-->mL) and $ 202.2 (39%) vs. hyaluronic acid. In Panama, the savings derived from its use were $154.6 (28%) vs. hylan G-F 20 (2<!--> <!-->mL) and $567.7 (58%) vs. hyaluronic acid. In the budget impact analysis, considering a gradual substitution over 5 years, the introduction of hylan G-F 20 (6<!--> <!-->mL) would be associated with savings of $138,513 (2%) in El Salvador, and $290,728 (3.6%) in Panama.</p></div><div><h3>Conclusions</h3><p>Viscosupplementation with hylan G-F 20 (6<!--> <!-->mL) in patients with knee osteoarthrosis is a cost-saving alternative when compared to hylan G-F 20 (2<!--> <!-->mL) and low molecular weight hyaluronic acid derivatives available in El Salvador and Panama.</p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49049925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Escleromixedema con manifestación extracutánea pulmonar: reporte de un caso y revisión de la literatura 伴有皮外肺部表现的硬肌水肿:病例报告和文献综述
Revista Colombiana de Reumatologia Pub Date : 2024-04-01 DOI: 10.1016/j.rcreu.2024.02.001
Vanessa Bedoya-Joaqui , María J. Varela-Muñoz , Luis G. Parra-Lara , María C. Garzón-Portilla , Liliana Muñoz , David A. Aguirre-Valencia
{"title":"Escleromixedema con manifestación extracutánea pulmonar: reporte de un caso y revisión de la literatura","authors":"Vanessa Bedoya-Joaqui ,&nbsp;María J. Varela-Muñoz ,&nbsp;Luis G. Parra-Lara ,&nbsp;María C. Garzón-Portilla ,&nbsp;Liliana Muñoz ,&nbsp;David A. Aguirre-Valencia","doi":"10.1016/j.rcreu.2024.02.001","DOIUrl":"10.1016/j.rcreu.2024.02.001","url":null,"abstract":"<div><p>Scleromyxoedema is a cutaneous fibromucinosis of unknown aetiology. It is associated with haematological dyscrasias and quite diverse manifestations. Pulmonary vascular involvement is rare and requires a differential diagnosis approach with systemic sclerosis. The case of a patient with scleromyxoedema with an extracutaneous pulmonary manifestation is described.</p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140275764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Temporal arteritis caused by eosinophilic vasculitis associated with a lymphocytic variant of the hypereosinophilic syndrome: A case report 嗜酸性血管炎引起的颞动脉炎伴嗜酸性粒细胞增多综合征的淋巴细胞变异:一例报告
Revista Colombiana de Reumatologia Pub Date : 2024-04-01 DOI: 10.1016/j.rcreu.2023.02.010
Roberto Benavides , Andrés Felipe Ramírez-Peralta , Marcela Muñoz-Urbano , Leonardo Mejía , Andrés Felipe Cardona-Cardona , Carlos Horacio Muñoz-Vahos
{"title":"Temporal arteritis caused by eosinophilic vasculitis associated with a lymphocytic variant of the hypereosinophilic syndrome: A case report","authors":"Roberto Benavides ,&nbsp;Andrés Felipe Ramírez-Peralta ,&nbsp;Marcela Muñoz-Urbano ,&nbsp;Leonardo Mejía ,&nbsp;Andrés Felipe Cardona-Cardona ,&nbsp;Carlos Horacio Muñoz-Vahos","doi":"10.1016/j.rcreu.2023.02.010","DOIUrl":"10.1016/j.rcreu.2023.02.010","url":null,"abstract":"<div><p>Temporal arteritis in patients under the age of 50 years is an unusual form of vasculitis with a group of aetiologies that include rheumatological and hematological diseases. Additionally, vasculitis mimickers should be excluded. We describe a case of temporal arteritis due to eosinophilic vasculitis in a 36-year-old woman, associated with a lymphocytic-variant of hypereosinophilic syndrome. She presented facial and neck swelling, pruritic hive-like lesions, subtle thickening in the left temporal artery, headache, visual alterations, mandibular claudication, and hypereosinophilia. The temporal artery biopsy confirmed panmural eosinophilic vasculitis, and peripheral blood and bone marrow flow cytometry revealed T lymphocytes with aberrant immunophenotype (CD3<sup>−</sup>CD4<sup>+</sup>). This case report describes the clinical features, histology, and treatment of temporal arteritis in young patients and hypereosinophilic syndrome, as well as clues for their differential diagnosis.</p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49500267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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