Revista Colombiana de Reumatologia最新文献

{"title":"Artralgias y displasia de cadera: sobre el síndrome trico-rino-falángico","authors":"Pablo González del Pozo,&nbsp;Paula Álvarez Peñalba,&nbsp;Norma Alejandra Callejas Pineda,&nbsp;Marta Loredo Martínez,&nbsp;Ignacio Braña Abascal,&nbsp;María Isabel Zapico Fernández,&nbsp;Sara Alonso Castro","doi":"10.1016/j.rcreu.2025.04.006","DOIUrl":"10.1016/j.rcreu.2025.04.006","url":null,"abstract":"<div><h3>Introduction</h3><div>Tricho-Rhino-Phalangeal Syndrome (TPRS) is a rare genetic and heterogeneous entity distinguished by skeletal abnomalities, growth retardation, distinctive facial features, ectodermal alterations —thin and depigmented hair, nail dystrophy— and also variable intellectual disability.</div></div><div><h3>Objective</h3><div>We present the case of a woman patient referrered to Rheumatology because of progressive-course mechanical joint pain for few years and previous-known pathology on hips.</div></div><div><h3>Conclusion</h3><div>Although infrequently, it is a musculo-skeletal entity that must be recognised by rheumatologists.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 102188"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poliarteritis nodosa: una rara complicación de infección por VIH, reporte de un caso","authors":"Jennifer Delgadillo Velásquez ,&nbsp;Julia Recalde-Reyes ,&nbsp;Oscar Rodrigo Vargas ,&nbsp;Luis Javier Cajas Santana","doi":"10.1016/j.rcreu.2026.504867","DOIUrl":"10.1016/j.rcreu.2026.504867","url":null,"abstract":"<div><h3>Introduction</h3><div>HIV-associated vasculitis is rare. Cases involving small and medium-sized vessels have been reported, usually in the form of polyarteritis nodosa (PAN). Diagnosis is challenging, and treatment is even more challenging in immunocompromised patients.</div></div><div><h3>Case Summary</h3><div>We describe the case of a 42-year-old patient with a history of HIV infection who was presented with skin lesions and critical ischemia in the lower limbs. Diagnostic studies, treatment, and outcome are detailed.</div></div><div><h3>Conclusion</h3><div>Vasculitis are common clinical entities, but their association with HIV infection is rare. Their presentation has become increasingly rare since the introduction of antiretroviral therapy, with very few cases described in the literature. Their appearance is a cause of significant morbidity and requires multidisciplinary and careful management to minimize risks.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 504867"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical characteristics and outcomes of Colombian patients with Takayasu arteritis: A retrospective cohort","authors":"Fabio Torres Saavedra ,&nbsp;Lina León Sierra ,&nbsp;Gloria Vásquez ,&nbsp;Luis Alonso González Naranjo ,&nbsp;Adriana Lucía Vanegas García ,&nbsp;Carlos Horacio Muñoz Vahos","doi":"10.1016/j.rcreu.2026.504868","DOIUrl":"10.1016/j.rcreu.2026.504868","url":null,"abstract":"<div><h3>Introduction</h3><div>Takayasu arteritis (TAK) is a vasculitis of the great vessels that affects mainly young patients. Cardiovascular morbidity is high due to irreversible damage, end-organ failure, and a late diagnosis. The knowledge of this vasculitis in our country is limited. This study describes clinical, laboratory, and angiographic findings of Takayasu arteritis in Colombia.</div></div><div><h3>Methods</h3><div>We described a retrospective cohort of patients with Takayasu arteritis in two rheumatology centers in Medellin, Colombia between 2011 and 2018. We assessed the medical records of 43 patients, 88% of whom met Takayasu arteritis 1990 ACR criteria.</div></div><div><h3>Results</h3><div>Of the forty-three patients, forty-one were female, with a median age of 22 years at diagnosis. Eleven patients were &gt;40 years old. The median delay in diagnosis was 12 months. Systemic manifestations included general malaise (32%), weight loss (23%), and fever (21%). The most frequent vascular symptoms were headache (39%) and upper limb claudication (30%). The most frequent physical examination findings were absent or decreased pulses (76%), hypertension (62%), blood pressure difference (60%), and subclavian murmur (48%). Eighty three percent and 76% of patients had elevated erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), respectively. Angiography (mainly magnetic resonance [MR] angiography) showed stenosis in the left subclavian artery (68%), followed by aortic involvement, including abdominal (62%) and thoracic (52%) segments. Hata–Numano's classification was V (62%), I (16%), and IIa (7%). Renal artery abnormalities, pulmonary artery stenosis, and aortic regurgitation were present in 42%, 14%, and 9%, respectively. Vascular complications were renovascular hypertension (30%), ischemic stroke, chronic kidney disease, and heart failure (all with 18%). Twenty-eight patients (65%) completed the 5-year follow-up. The overall survival rate was 83% in the fifth year, compared to 87.5% in the first.</div></div><div><h3>Conclusions</h3><div>A high rate of complicated vascular lesions (Hata–Numano V and renal/splanchnic artery disease), ongoing disease activity, and a late diagnosis may be the causes of the increased morbidity observed in this cohort of TAK patients.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 504868"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guías colombianas de osteoporosis: hacia una atención más integral y preventiva","authors":"Adriana Medina","doi":"10.1016/j.rcreu.2026.504915","DOIUrl":"10.1016/j.rcreu.2026.504915","url":null,"abstract":"","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 504915"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilización de medicamentos relacionados con el manejo de osteoartritis en Colombia: estudio descriptivo de corte transversal","authors":"Miguel Eduardo Rubio Toloza ,&nbsp;Manuel Enrique Machado Duque","doi":"10.1016/j.rcreu.2025.03.006","DOIUrl":"10.1016/j.rcreu.2025.03.006","url":null,"abstract":"<div><h3>Introduction</h3><div>The prevalence of osteoarthritis in the Colombian population is estimated at 10.8% and is associated with high health costs. The evaluation of the benefit-risk of the pharmacological treatment used is a fundamental aspect for all health professionals.</div></div><div><h3>Objective</h3><div>To identify the profile of medication use related to the management of osteoarthritis in adults over 50<!--> <!-->years of age in Colombia in 2022 and with an unfavourable benefit-risk ratio.</div></div><div><h3>Methods</h3><div>A quantitative, descriptive, cross-sectional study, taking into account all prescription dispensations of patients over 50<!--> <!-->years of age with a diagnosis of osteoarthritis, affiliated with the health plan of a Colombian insurer in 2022. The risk-benefit ratio was determined according to the <em>Prescrire</em> journal and the applicable STOPP criteria.</div></div><div><h3>Results</h3><div>A total of 18,824 patients were included, the median age found was 64<!--> <!-->years. Of these, 74.8% were women. The prevalence of prescription of medications related to osteoarthritis was 0.4% of all affiliates for the year 2022 by said insurer. The most prescribed medication was acetaminophen-codeine in 46.5% of patient dispensations. A total of 64.2% of users were prescribed drugs with an unfavourable benefit-risk ratio according to the <em>Prescrire</em> journal and STOPP criteria.</div></div><div><h3>Conclusions</h3><div>A significant proportion of prescriptions related to the management of osteoarthritis identified in this study contain at least one drug with an unfavourable benefit-risk ratio. This finding highlights the need to reflect on the optimization of prescribing, especially considering the chronic nature of osteoarthritis.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 102182"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of physical activity in patients with common low back pain: A case–control study","authors":"Fazaa Alia ,&nbsp;Kamoun Mariem ,&nbsp;Boussaa Hiba ,&nbsp;Miladi Saoussen ,&nbsp;Makhlouf Yasmine ,&nbsp;Ben Abdelghani Kawther ,&nbsp;Laatar Ahmed","doi":"10.1016/j.rcreu.2026.504869","DOIUrl":"10.1016/j.rcreu.2026.504869","url":null,"abstract":"<div><h3>Introduction</h3><div>Physical activity (PA) can help reduce pain and physical deconditioning. The main aim of our study was to assess the PA level in patients with low back pain (LBP) and in healthy controls, using a self-report questionnaire.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional case–control study of a group of patients followed for more than 12 weeks with LBP and a control group. PA was assessed using the International Physical Activity Questionnaire (IPAQ). Sedentary mean time was measured in minutes per week.</div></div><div><h3>Results</h3><div>Patients and controls had the same gender proportion: 33 patients and 33 controls (7 men and 26 women) were included. In the patients, the mean duration of LBP was 6<!--> <!-->±<!--> <!-->6.7 years. Total PA was lower in patients (4524<!--> <!-->±<!--> <!-->4084 MET (metabolic equivalent of task)-min/week [99–17228]) than in controls (5782<!--> <!-->±<!--> <!-->7598 MET-min/week [120–30933]) (<em>p</em> <!-->=<!--> <!-->0.293). Thirty-three percent of patients did not meet World Health Organization (WHO) recommendations for PA for health versus 13% of controls (<em>p</em> <!-->=<!--> <!-->0.05). Level of PA was high in 42% of patients versus 34% of controls (<em>p</em> <!-->=<!--> <!-->0.05). Weekly sedentary time was lower in patients than in controls (<em>p</em> <!-->=<!--> <!-->0.076). According to patients, main factors for physical inactivity were lack of free time (48.5%) and LBP pain (33%). In univariate analysis, low PA level was significantly associated with spinal mobility as assessed by the ST (<em>p</em> <!-->=<!--> <!-->0.006).</div></div><div><h3>Conclusion</h3><div>Given the evidence of feasibility and safety, a PA adapted and personalized for each individual suffering from chronic LBP should be an integral part of their treatment.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 504869"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasonographic evaluation of nail involvement in psoriatic arthritis: A systematic review and meta-analysis","authors":"Jairo Cajamarca-Barona ,&nbsp;Catalina Sanmiguel-Reyes ,&nbsp;Jhon Buitrago ,&nbsp;Laura Gallego ,&nbsp;Diana Guavita-Navarro ,&nbsp;Jose Yate ,&nbsp;Ana María Arredondo ,&nbsp;Hector Cubides ,&nbsp;Alejandro Escobar ,&nbsp;Adriana Rojas-Villarraga ,&nbsp;Diego Javier Martínez Lozano","doi":"10.1016/j.rcreu.2026.504877","DOIUrl":"10.1016/j.rcreu.2026.504877","url":null,"abstract":"<div><h3>Introduction and objective</h3><div>Nail involvement is a hallmark of psoriatic arthritis (PsA), often reflecting disease severity and systemic inflammation. Subclinical nail changes frequently precede joint symptoms, making early detection essential for timely intervention. Ultrasonography, with its high-frequency probes and power Doppler technology, provides a non-invasive method to assess nail structures and inflammatory activity. Our systematic review and meta-analysis concentrate on the role of ultrasound (US) in identifying subclinical or early PsA-related nail changes – particularly nail plate and nail bed thickness.</div></div><div><h3>Materials and methods</h3><div>A systematic review and meta-analysis were conducted following the PRISMA guidelines. Nine studies were included for qualitative synthesis, and three studies for quantitative meta-analysis. A comprehensive search of PubMed and EMBASE was performed using MeSH terms and keywords including “psoriatic arthritis,” “nail,” and “ultrasonography.” Random-effects models calculated pooled mean differences for nail thickness, and heterogeneity was assessed using the <em>I</em>² statistic.</div></div><div><h3>Results</h3><div>Among 253 participants (175 PsA, 78 controls), patients with PsA exhibited significantly increased nail plate thickness (mean difference: 0.11<!--> <!-->mm, 95% CI: 0.07–0.15, <em>p</em> <!-->&lt;<!--> <!-->0.001, <em>I</em>² <!-->=<!--> <!-->12%) and nail bed thickness (mean difference: 0.20<!--> <!-->mm, 95% CI: 0.14–0.26, <em>p</em> <!-->&lt;<!--> <!-->0.001, <em>I</em>² <!-->=<!--> <!-->18%). Ultrasonographic findings also revealed subclinical enthesitis and increased power Doppler signals indicative of active inflammation. Consistent results across studies highlight ultrasonography's diagnostic reliability.</div></div><div><h3>Conclusion</h3><div>Ultrasonography is a robust, non-invasive method for evaluating nail involvement in PsA, with increased nail plate and bed thickness serving as reliable markers of disease activity. Standardization of ultrasonographic protocols and further multicenter studies are recommended to validate these findings and expand their clinical application.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 504877"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vasculitis asociada a ANCAs con compromiso pulmonar severo como efecto adverso del propiltiouracilo. Reporte de caso","authors":"José S. Cortés ,&nbsp;Javier Alejandro Correa ,&nbsp;Wilder Carvajal ,&nbsp;Wilmer Aponte ,&nbsp;Luis Javier Cajas","doi":"10.1016/j.rcreu.2026.504866","DOIUrl":"10.1016/j.rcreu.2026.504866","url":null,"abstract":"<div><h3>Introduction</h3><div>Propylthiouracil (PTU) is used to treat Graves’ disease and has been reported to induce antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).</div></div><div><h3>Case report</h3><div>A 54-year-old woman with Graves’ disease developed PTU-associated AAV, manifested by diffuse alveolar hemorrhage complicated by pneumonia and pleural effusion. As part of her treatment, she received methylprednisolone, prednisolone, and rituximab. The patient showed remarkable pulmonary recovery at three-month follow-up.</div></div><div><h3>Conclusions</h3><div>This case highlights the importance of early recognition of PTU-induced AAV and the progression of a severe pulmonary complication.</div><div>.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 504866"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salivary gland ultrasound: From standard protocols to clinical impact in rheumatology","authors":"Karen Tatiana Gualdrón-Chaparro ,&nbsp;Juan David Urriago-Gil ,&nbsp;José Santiago Cortés Guzmán ,&nbsp;Sofia C. Barreira ,&nbsp;Santiago Bernal-Macías","doi":"10.1016/j.rcreu.2026.504873","DOIUrl":"10.1016/j.rcreu.2026.504873","url":null,"abstract":"<div><div>Ultrasound of the salivary and parotid glands has become a valuable tool in rheumatology, especially in the assessment of patients with sicca symptoms, including those with Sjögren's syndrome (SjS). This imaging modality offers a non-invasive approach with proven sensitivity for diagnosis, disease differentiation, and treatment response assessment. This article presents a comprehensive literature review on the use of salivary gland ultrasound (SGUS) in various conditions associated with sicca symptoms, focusing on its application in SjS and other diseases like sarcoidosis, IgG4-related disease (IgG4-RD), and amyloidosis. We summarize the SGUS protocol, normal and pathological findings, and the OMERACT scoring system that standardizes SGUS interpretation. Studies show SGUS provides significant diagnostic support in SjS, with potential utility in assessing other connective tissue and infiltrative diseases, although its role in non-SjS conditions remains under study. Further validation is needed to define its role in clinical algorithms, especially in non-SjS etiologies, and to establish its prognostic value in treatment response. SGUS may improve the sensitivity and specificity of established diagnostic criteria, though it does not entirely replace biopsy in certain cases. Future research should further validate SGUS in diverse rheumatic conditions.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 504873"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on ultrasound in spondyloarthritis and psoriatic arthritis","authors":"Sebastián Herrera Uribe ,&nbsp;Erika Marcela Padilla Martínez ,&nbsp;Diana Padilla-Ortiz ,&nbsp;Emilio Filippucci","doi":"10.1016/j.rcreu.2026.504871","DOIUrl":"10.1016/j.rcreu.2026.504871","url":null,"abstract":"<div><div>Musculoskeletal ultrasound has emerged as an important imaging modality in the diagnosis and management of spondyloarthritis and psoriatic disease offering detailed insights that help guide clinical decision-making and optimizing patient care. We aim to review its utility in diagnosis, treatment, prognosis and special situations in both diseases.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 504871"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}