Revista Colombiana de Reumatologia最新文献

{"title":"A propósito de autoinmunidad y COVID-19 en pediatría","authors":"Adriana Diaz-Maldonado","doi":"10.1016/j.rcreu.2024.09.001","DOIUrl":"10.1016/j.rcreu.2024.09.001","url":null,"abstract":"","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 4","pages":"Pages 433-434"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142432800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autoinmunidad en pacientes pediátricos de una región de Colombia, tras un pico de SARS-CoV-2","authors":"","doi":"10.1016/j.rcreu.2023.08.001","DOIUrl":"10.1016/j.rcreu.2023.08.001","url":null,"abstract":"<div><h3>Introduction</h3><div>With the onset of the 2019 coronavirus pandemic, there was an increase in the number of reported cases of autoimmune manifestations in the midst of the disease and new cases of autoimmunity after infection.</div></div><div><h3>Objective</h3><div>To correlate the rate of positive tests of SARS-CoV-2 with the rate of new diagnoses of autoimmune disease in paediatric patients of the department of Huila (Colombia), between March 2020 and September 2021.</div></div><div><h3>Methods</h3><div>The socio-demographic characterization of the subjects diagnosed with autoimmune disease and of the cases of SARS-CoV-2 was performed; an analysis of the monthly trend of events was performed and a correlation model was applied between the rate of SARS-CoV-2 diagnosis and the rate of autoimmune diseases during the study period.</div></div><div><h3>Results</h3><div>A total of 94 cases of autoimmune disease were diagnosed, with an average age of 8.3<!--> <!-->years, most were girls and belonged to the urban area and the subsidized regimen, and immune thrombocytopenic purpura was the most common diagnosis. In addition, 4,303 cases of SARS-CoV-2 were detected, mostly adolescents, from urban areas and the contributory system. Finally, it was evidenced that the highest rate of autoimmune disease was reported just after the highest peak of SARS-CoV-2.</div></div><div><h3>Conclusions</h3><div>This study did not show a statistical correlation between the rate of SARS-CoV-2 and the rate of diagnoses of autoimmune disease; however, it showed an enormous peak of autoimmunity after the highest peak of infection in paediatric patients of the department during the first eighteen months of the pandemic.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 4","pages":"Pages 442-451"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139304262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluación de desenlaces clínicos en los pacientes con artritis reumatoide desde la perspectiva del paciente: revisión narrativa de la literatura","authors":"","doi":"10.1016/j.rcreu.2023.08.007","DOIUrl":"10.1016/j.rcreu.2023.08.007","url":null,"abstract":"<div><h3>Introduction</h3><div>The evaluation of clinical outcomes in rheumatoid arthritis patients, including the patient's perspective, allows the inclusion of the patient's perspective in clinical decision-making using instruments designed for this purpose.</div></div><div><h3>Objective</h3><div>To identify and describe the instruments validated in Spanish to evaluate clinical outcomes in rheumatoid arthritis in daily clinical practice and from the patient's perspective, including disease activity, functionality, impact of the disease, adherence to treatment and quality of life.</div></div><div><h3>Materials and methods</h3><div>A review of the literature in various databases (PubMed, Scopus, Bireme, Scielo) was conducted e looking for questionnaires that evaluate clinical outcomes in rheumatoid arthritis patients, including those with a validated Spanish translation that allow self-assessment of the disease by the patient and clinical monitoring.</div></div><div><h3>Results</h3><div>Fifteen questionnaires were identified and selected that met the inclusion criteria. Four instruments were found that evaluate quality of life, three that evaluate functionality, four that evaluate disease impact, one that evaluate disease activity, and three that evaluate adherence to treatment.</div></div><div><h3>Conclusion</h3><div>Questionnaires and scales that evaluate rheumatoid arthritis allow a clinical approach to the evolution of the disease as perceived and reported by the patients, optimizing clinical follow up. Implementation of these tools in clinical decision making allows for an improvement in quality of care of patient with this condition.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 4","pages":"Pages 489-497"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135565146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inadequate sleep as a limiting factor in achieving remission in patients with rheumatoid arthritis","authors":"","doi":"10.1016/j.rcreu.2023.05.005","DOIUrl":"10.1016/j.rcreu.2023.05.005","url":null,"abstract":"<div><h3>Introduction</h3><div>Good sleep has a restorative effect at the cellular level and helps maintain the body's homeostasis.</div></div><div><h3>Objectives</h3><div>Given our clinical experiences, we propose that sleep quality should be evaluated in patients with rheumatoid arthritis. Poor sleep quality should be considered as a factor that may impact clinical outcomes in patients with rheumatoid arthritis.</div></div><div><h3>Materials and methods</h3><div>We researched medical literature on clinical and physiological pathways associated with sleep quality.</div></div><div><h3>Results</h3><div>There is evidence that interleukin-6 and tumor necrosis factor have a role in inflammatory and immune imbalance as well as in sleep disturbance in patients with rheumatoid arthritis, which leads to the chronic inflammatory process seen in these patients. Most patients with rheumatoid arthritis report sleep problems, be it insomnia or other complaints of non-refreshing sleep. Lack of sleep or poor sleep patterns in these patients further compromise their quality of life. In patients with RA, aetiologies such as restless leg syndrome (RLS), sleep apnoea syndrome, and Temporomandibular Joint Dysfunction (TMJ) syndromes might contribute to sleep disturbances. This lack of restful sleep might limit our goal, as treating physicians, to achieve remission states in these patients.</div></div><div><h3>Conclusions</h3><div>It is our opinion that sleep quality evaluation must be addressed, monitored, and treated as part of the management of patients with RA. Bad sleep adds an additional burden to disease activity in patients with RA, besides, it limits patients’ possibility of achieving disease remission.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 4","pages":"Pages 517-522"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41701564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tolerancia central de las células T, ¿qué hay de nuevo?","authors":"","doi":"10.1016/j.rcreu.2023.08.002","DOIUrl":"10.1016/j.rcreu.2023.08.002","url":null,"abstract":"<div><h3>Introduction</h3><div>Random somatic recombination of T<!--> <!-->cell receptors facilitates the variability of response to foreign antigens. Then, central tolerance occurs, a mechanism designed to avoid exit of autoreactive T<!--> <!-->cells from the thymus. However, failures in this process can induce the appearance of autoimmunity.</div></div><div><h3>Materials and methods</h3><div>This narrative review was conducted through a literature search focused on describing relevant and recent concepts of central tolerance of T<!--> <!-->cells.</div></div><div><h3>Results</h3><div>Multiple cell groups are part of the thymic microenvironment, among them, thymic epithelial cells are responsible for directing development of thymocytes, especially medullary thymic epithelial cells that direct the negative selection process.</div></div><div><h3>Conclusions</h3><div>Factors that affect thymocytes, the thymic microenvironment, or interaction between them, can lead to development of immunodeficiencies and/or autoimmunity.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 4","pages":"Pages 480-488"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135606267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison of core muscle endurance of females with fibromyalgia versus healthy females: An observational study","authors":"Dewanshu Sindwani,&nbsp;Manjyot Kaur","doi":"10.1016/j.rcreu.2023.10.001","DOIUrl":"10.1016/j.rcreu.2023.10.001","url":null,"abstract":"<div><h3>Introduction</h3><div>Despite the numerous benefits of core muscle strengthening in improving symptoms of fibromyalgia (FM), limited studies have quantified core muscle function in FM patients.</div></div><div><h3>Objective</h3><div>To compare the core muscle endurance of FM<span> females with age-matched healthy females and determine whether a correlation exists between core muscle endurance and FM severity.</span></div></div><div><h3>Materials and methods</h3><div><span>Pre-diagnosed female FM patients (</span><em>n</em> <!-->=<!--> <!-->7) and age-matched healthy females (<em>n</em> <!-->=<!--> <!-->19) were assessed using McGill's core endurance tests in four positions – flexion, extension, and bilateral side-bridge. The longest contraction holding time (in seconds) in each position was noted and compared in both groups. Additionally, patient-reported Fibromyalgia Impact Questionnaire (FIQ) scores were obtained to determine disease severity.</div></div><div><h3>Results</h3><div>The mean holding time for trunk extensors (26.14<!--> <!-->±<!--> <!-->7.7<!--> <!-->s), right lateral flexors (20.14<!--> <!-->±<!--> <!-->8.3<!--> <!-->s), and left lateral flexors (20.86<!--> <!-->±<!--> <!-->5.3<!--> <!-->s) was significantly lower in the FM females than the healthy females (trunk extensors<!--> <!-->=<!--> <!-->55.21<!--> <!-->±<!--> <!-->17.1<!--> <!-->s; right lateral flexors<!--> <!-->=<!--> <!-->36.05<!--> <!-->±<!--> <!-->13.2<!--> <!-->s; left lateral flexors<!--> <!-->=<!--> <!-->35.11<!--> <!-->±<!--> <!-->13.8<!--> <!-->s). The endurance of trunk flexors was statistically similar in both groups (FM females<!--> <!-->=<!--> <!-->52.14<!--> <!-->±<!--> <!-->27.9<!--> <!-->s; healthy females<!--> <!-->=<!--> <!-->74.37<!--> <!-->±<!--> <!-->37.7<!--> <span>s). Lastly, core muscle endurance was not correlated with the FIQ scores in FM patients (</span><em>p</em> <!-->&gt;<!--> <!-->0.05).</div></div><div><h3>Conclusion</h3><div>The results of this preliminary study revealed that core extensor and lateral flexor endurance in FM females was lower than their healthy female counterparts. Larger sample studies are needed to further substantiate our findings.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 4","pages":"Pages 473-479"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Balancing inflammation and adverse effects of glucocorticoids in clinical practice","authors":"Juan Sebastián Peinado-Acevedo ,&nbsp;Tatiana Rivera-Bustamante ,&nbsp;Jairo Rivera ,&nbsp;Yeison Santamaría-Alza","doi":"10.1016/j.rcreu.2023.08.004","DOIUrl":"10.1016/j.rcreu.2023.08.004","url":null,"abstract":"<div><div>Corticosteroids play a vital role in enabling the body to tolerate stressful situations and regulate the inflammatory process. Excessive or persistent inflammation can lead to tissue damage and the development of diseases. Glucocorticoids are crucial in modulating the impact of inflammatory disorders, such as allergies, autoimmune diseases, and sepsis. These disorders can be life-threatening and benefit from glucocorticoid administration. Natural and synthetic glucocorticoids are utilized for the diagnosis and treatment of adrenal function disorders and various inflammatory, immune, and neoplastic conditions. The discovery of glucocorticoids is a testament to the ingenuity and collaboration of researchers. For over 70 years, glucocorticoids have revolutionized medicine and are widely employed in various medical conditions. This article provides a comprehensive review of the critical considerations for the clinical application of glucocorticoids, aiming to strike a balance between their benefits and potential risks. Understanding its history, chemical structure, pharmacology, and mechanisms of action provides the foundation for achieving proper use of this type of medication.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 4","pages":"Pages 498-510"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fe de errores del artículo «Complicación hematológica con impacto pulmonar en una paciente con síndrome de Sjögren» [Rev Colomb Reumatol. 2024;31(2):259-263]","authors":"Laura Gallego ,&nbsp;Jhon Buitrago ,&nbsp;Diana Guavita-Navarro ,&nbsp;Jairo Cajamarca-Barón ,&nbsp;Ana María Arredondo ,&nbsp;José Fernando Polo Nieto ,&nbsp;Juan Pablo Castañeda-González ,&nbsp;Alejandro Escobar","doi":"10.1016/j.rcreu.2024.04.006","DOIUrl":"10.1016/j.rcreu.2024.04.006","url":null,"abstract":"","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 3","pages":"Page 431"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0121812324000550/pdfft?md5=3cdb0eb9eb53f98b30d3330767ce7292&pid=1-s2.0-S0121812324000550-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141951555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive health assessment based on ICF components using the WOMAC index in patients with osteoarthritis","authors":"","doi":"10.1016/j.rcreu.2022.08.003","DOIUrl":"10.1016/j.rcreu.2022.08.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Osteoarthritis (OA) is a common degenerative disease associated with functional impairment, activity limitation, participation restriction, and poor quality of life. Therefore, comprehensive assessment is important to determine how complex problems affect patients with OA.</p></div><div><h3>Objectives</h3><p>The first aim of this study was to link and allocate items of The Western Ontario and McMaster Universities (WOMAC) OA index with the ICF Comprehensive Core Set for OA. The second aim was to examine the relationship between quality of life and each ICF component score based on WOMAC clinical data in OA.</p></div><div><h3>Materials and methods</h3><p>Health status was evaluated with WOMAC and quality of life with the Nottingham Health Profile (NHP). The WOMAC items were linked with codes of the ICF Comprehensive Core Set for OA and allocated with the ICF components by three researchers. The relationship between WOMAC scores and the NHP was determined by Pearson correlation analysis.</p></div><div><h3>Results</h3><p>87 patients with OA were included. As distinguished by the researchers, 7 items of WOMAC covered body function and 17 covered activity-participation. Body function and activity-participation had a moderate correlation with the pain subtest of the NHP and low correlation with the energy level subtest and total score of the NHP. Activity-participation had a high correlation with the physical abilities subtest of the NHP.</p></div><div><h3>Conclusion</h3><p>Although WOMAC does not cover environmental factors, it is a comprehensive tool to assess health status and quality of life. Our results showed that in OA physical abilities can lead to limitations in activity and participation, and these limitations are associated with the individual's pain, energy level, and quality of life.</p><p>Clinical trial registration number: NCT04956510.</p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 3","pages":"Pages 356-364"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47440354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A retrospective study of neonatal and pregnancy outcomes in pregnant women suffering from inflammatory arthropathy treated with adalimumab","authors":"","doi":"10.1016/j.rcreu.2023.05.002","DOIUrl":"10.1016/j.rcreu.2023.05.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Anti-tumor necrosis factor-alpha (TNF-α) treatments have been available for over two decades to treat inflammatory arthropathies (IA). Most of these disorders are common among women of reproductive age, which emphasizes the need to evaluate their safety in pregnancy.</p></div><div><h3>Objective</h3><p>This study aims to scrutinize neonatal and pregnancy outcomes in pregnant IA patients treated with adalimumab.</p></div><div><h3>Materials and methods</h3><p>The current cross-sectional work was conducted by reviewing the medical files of pregnant IA patients (<em>n</em> <!-->=<!--> <!-->30) receiving adalimumab referred to Golestan Hospital in Ahvaz (Iran) from 2014 to 2017, followed by extracting demographic profiles as well as neonatal and pregnancy outcomes.</p></div><div><h3>Results</h3><p>Noteworthy among the findings were PsA (<em>n</em> <!-->=<!--> <!-->13), RA (<em>n</em> <!-->=<!--> <!-->5), IBD (<em>n</em> <!-->=<!--> <span>4), AS (</span><em>n</em> <!-->=<!--> <!-->3), uveitis (<em>n</em> <!-->=<!--> <!-->2), Behcet's disease (<em>n</em> <!-->=<!--> <!-->2), and panuveitis (<em>n</em> <!-->=<!--> <!-->1). The mean age of subjects, duration of illness, and duration of treatment were estimated at 29.53<!--> <!-->±<!--> <!-->5.88, 2.85<!--> <!-->±<!--> <!-->1.15, and 1.96<!--> <!-->±<!--> <!-->.90 years, respectively. No delivery outcome was found for 27 (90%) cases, and delivery outcomes observed in three (10%) patients were abortion (<em>n</em> <!-->=<!--> <!-->2) and preterm complications (<em>n</em> <!-->=<!--> <!-->1). No neonatal complication was found for 28 (93.3%) cases and neonatal IUGR outcome was reported in 2 (6.7%) cases. Cesarean section was a delivery method in 7 (23.3%) cases and natural method in 21 (70%) cases. There were no significant differences for the prevalence of cesarean section and neonatal outcomes based on the type of disease, but differences were observed for the outcome of delivery based on the type of disease.</p></div><div><h3>Conclusion</h3><p>According to our findings, definitive conclusions on the safety of adalimumab during pregnancy were impossible and there is a need for further research with a larger sample size.</p></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"31 3","pages":"Pages 290-295"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48934309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}