Revista Colombiana de Reumatologia最新文献

{"title":"Comite Editorial online","authors":"","doi":"10.1016/S0121-8123(24)00103-8","DOIUrl":"10.1016/S0121-8123(24)00103-8","url":null,"abstract":"","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"32 1","pages":"Pages E1-E3"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143133945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum interleukin-41 concentrations are decreased in women with rheumatoid arthritis and are not affected by menopausal status, disease activity, or medication","authors":"Dhuha F.N. Bani-Wais ,&nbsp;Ali H. Ad’hiah","doi":"10.1016/j.rcreu.2023.11.001","DOIUrl":"10.1016/j.rcreu.2023.11.001","url":null,"abstract":"<div><h3>Introduction</h3><div>Rheumatoid arthritis (RA) is an autoimmune inflammatory disorder characterized by immunobiological homeostasis. The recently discovered cytokine interleukin-41 (IL-41) is among the immunobiological components suggested to have modulatory effects in RA and has shown up-regulated levels in patients. However, IL-41 has not been explored during the pre- (PRM) and post-menopausal (POM) periods in women with RA, and its relationship to disease activity and medications has not been well studied.</div></div><div><h3>Materials and methods</h3><div>In this case–control study, serum IL-41 concentrations were quantified in 120 women with RA (70 PRM and 50 POM) and 110 control women using an enzyme-linked immunosorbent assay kit. Thirty patients were newly diagnosed (ND) and 90 patients were on treatment with etanercept (a tumor necrosis factor inhibitor; TNF) plus methotrexate (MD).</div></div><div><h3>Results</h3><div>Median IL-41 concentrations (interquartile range) were significantly lower in RA patients than in control women (49.8 [32.5–79.5] <em>vs</em>. 104.7 [76.9–134.6]<!--> <!-->pg/mL; probability &lt;.001). As indicated by the area under the curve, .827, IL-41 showed reliable discrimination between RA patients and HC. IL-41 concentrations stratified by menopausal status (PRM <em>vs</em>. POM), disease activity score 28 (&lt;3.2 <em>vs</em>. ≥3.2), and medication (ND <em>vs</em>. MD) showed no significant difference in each stratum.</div></div><div><h3>Conclusions</h3><div>In contrast to previous studies, serum IL-41 concentrations were significantly decreased in the present cohort of women with RA. These concentrations were not affected by menopausal status, disease activity, or medication. Data from the current study suggest that IL-41 is involved in the pathophysiology of RA.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"32 1","pages":"Pages 27-35"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139827241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evidencia terapéutica del mepolizumab en la granulomatosis eosinofílica con poliangeítis: una revisión exploratoria","authors":"Eduardo Tuta-Quintero ,&nbsp;Isabella Perna-Reyes ,&nbsp;Juan Olivella-Gómez ,&nbsp;Daniela Rodríguez-Fraile ,&nbsp;Juan C. Santacruz ,&nbsp;Andrea A. Mayorga-Borja ,&nbsp;John Londoño","doi":"10.1016/j.rcreu.2023.11.003","DOIUrl":"10.1016/j.rcreu.2023.11.003","url":null,"abstract":"<div><div>Mepolizumab (MPZ) is a therapeutic option for eosinophilic granulomatosis with polyangiitis (EGPA). However, the evidence on its efficacy, effectiveness, and safety is limited. Our results included 17 full-text articles evaluating the use of MPZ in patients diagnosed with EGPA, 47% (8/17) of the documents were case reports, 18% (3/17) retrospective cohort studies, 12% (2/17) clinical trials, and 6% corresponded to a prospective cohort (1/17), ambispective cohort (1/17), case series (1/17), and pilot study (1/17). The most frequently used dose of MPZ was 300 mg/month, described in 59% (10/17) of the included manuscripts. The decrease in the Birmingham Vasculitis Activity Score (BVAS), reduction in the dose of corticosteroids, and modulation in the number of eosinophils in the blood were the variables most used to determine the clinical effect in patients. Finally, 10 clinical trial records were included describing the design, conduct, and administration of the ongoing studies. The use of MPZ in patients with EGPA shows a reduction in the BVAS, saving oral corticosteroids and modulating blood hypereosinophilia. The adverse events described were mild and moderate in all the included studies.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"32 1","pages":"Pages 69-83"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139818067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factores asociados con el desarrollo de falla renal crónica terminal durante la hospitalización en los pacientes con poliangitis microscópica y granulomatosis con poliangitis en una población del noroccidente colombiano","authors":"Santiago Cobaleda Cano ,&nbsp;Andrés Felipe Echeverri García ,&nbsp;Adriana Margarita Trejos Tenorio ,&nbsp;Javier Darío Márquez Hernández ,&nbsp;Jhon Edwar García Rueda ,&nbsp;Luis Fernando Pinto Peñaranda","doi":"10.1016/j.rcreu.2023.11.004","DOIUrl":"10.1016/j.rcreu.2023.11.004","url":null,"abstract":"<div><h3>Introduction</h3><div>ANCA vasculitis has been associated with increased morbidity and mortality, high disease burden, and organ damage, especially renal.</div></div><div><h3>Objectives</h3><div>To determine factors associated with end-stage kidney disease at hospital discharge in microscopic polyangiitis and granulomatosis with polyangiitis patients, to characterize our population, hospitalization causes, treatment received, and complications during stay.</div></div><div><h3>Materials and methods</h3><div>Adults with previous or new diagnosis of microscopic polyangiitis and granulomatosis with polyangiitis who required hospitalization between January 01, 2013, and April 30, 2021, were included. Association with end-stage kidney disease development was evaluated by Pearson's Chi2 (χ²) or Fisher's test, and Student's t or Mann-Whitney U test according to the nature of the variables. Exploratory multivariate models were made including factors associated with end-stage kidney disease.</div></div><div><h3>Results</h3><div>Forty-three patients were included, microscopic polyangiitis 55.8, and granulomatosis with polyangiitis 44.25. Twelve patients (27.9%) developed early end-stage kidney disease. High blood pressure, high urea nitrogen levels on admission, as well as pulmonary oedema, and Five Factor Score &gt;<!--> <!-->1 entailed a higher risk. In contrast, normal kidney function on admission was a protective factor. Rapidly progressive glomerulonephritis and arterial hypertension on admission were associated with end-stage kidney disease. In adjusted exploratory models according to vasculitis type, Birmingham Vasculitis Activity Score, diffuse alveolar haemorrhage, and plasma exchange use were identified as factors to include in multivariate models in multicentre studies.</div></div><div><h3>Conclusion</h3><div>88% of patients had renal involvement and 27.9% developed end-stage kidney disease. Rapidly progressive glomerulonephritis and arterial hypertension on hospital admission were associated with early development of end-stage kidney disease while normal renal function on admission was a protective factor for this outcome.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"32 1","pages":"Pages 16-26"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140278259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Convergencia clínica: un caso excepcional de sarcoidosis y tuberculosis con múltiples manifestaciones orgánicas. Reporte de caso","authors":"Néstor Correa-González ,&nbsp;María Claudia Díaz ,&nbsp;Keyla Jemihah Triana Ángel ,&nbsp;María Daniela Polania ,&nbsp;Natalia Remolina Murillo ,&nbsp;Pilar Alarcón Robles","doi":"10.1016/j.rcreu.2024.01.004","DOIUrl":"10.1016/j.rcreu.2024.01.004","url":null,"abstract":"<div><h3>Introduction</h3><div>The diagnosis of sarcoidosis is challenging, especially if the patient has concomitant infectious symptoms. Furthermore, the overlap of immune-mediated and infectious pathologies is not uncommon.</div></div><div><h3>Objective</h3><div>To report a rare case of association between tuberculosis and sarcoidosis.</div></div><div><h3>Materials and methods</h3><div>Description of the clinical characteristics of a patient who presented with sarcoidosis superimposed on tuberculosis.</div></div><div><h3>Results</h3><div>The case of a 29-year-old man with ocular, cutaneous, and systemic symptoms is described. Uveitis and chronic non-caseating granulomatous findings were diagnosed in the skin, lungs, and lymph nodes. Suspicion of tuberculosis led to positive molecular biology tests only in the lymph node biopsy. An overlap of sarcoidosis and tuberculosis was determined, and combined treatment with glucocorticoids and anti-tuberculosis agents was initiated, resulting in improvement of the patient.</div></div><div><h3>Conclusions</h3><div>Sarcoidosis and tuberculosis share characteristics from their aetiology to clinical manifestations, posing a challenge in clinical differentiation. Cases have been documented where both diseases overlap in the same patient.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"32 1","pages":"Pages 95-102"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140399070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consenso para la gestión de riesgo en la prescripción de terapias biológicas o de antirreumáticos sintéticos con blanco dirigido: Asociación Colombiana de Reumatología 2023","authors":"Elías Gonzalo Forero Illera ,&nbsp;Andrés Ricardo Fernández Aldana ,&nbsp;Daniel Gerardo Fernández Ávila ,&nbsp;Edwin Antonio Jáuregui Cuartas ,&nbsp;Gloria Vásquez ,&nbsp;Monique Chalem ,&nbsp;Wilson Bautista Molano","doi":"10.1016/j.rcreu.2024.01.007","DOIUrl":"10.1016/j.rcreu.2024.01.007","url":null,"abstract":"","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"32 1","pages":"Pages 56-68"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143133938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Riesgo de tuberculosis en pacientes con inmunosupresión: en búsqueda de una vieja conocida","authors":"Jorge Alberto Cortés","doi":"10.1016/j.rcreu.2024.11.001","DOIUrl":"10.1016/j.rcreu.2024.11.001","url":null,"abstract":"","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"32 1","pages":"Pages 1-2"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143133946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estrategias para la organización de las consultas de reumatología","authors":"Juan Fernando Rivadeneira Jácome,&nbsp;Lara Montserrat González García","doi":"10.1016/j.rcreu.2023.11.002","DOIUrl":"10.1016/j.rcreu.2023.11.002","url":null,"abstract":"<div><h3>Introduction</h3><div>The prevalence of rheumatic disease in the general population is approximately 10%. At the same time, there has been an increase in the workload of rheumatology services, particularly concerning consultations. Many health institutions have limited the duration of rheumatology consultation to about 15<!--> <!-->min. This article demonstrates the need to lengthen the duration rheumatology consultations.</div></div><div><h3>Objective</h3><div>The goal of this work is to review the literature about the standards for the duration of rheumatology consultations and to propose new organizational strategies in this regard.</div></div><div><h3>Materials and methods</h3><div>A narrative review of the current literature related to care standards in rheumatology consultations was carried out, including the wide variety of diagnostic procedures, which decisively influence the duration of these consultations.</div></div><div><h3>Results</h3><div>Organizational strategies are proposed, based on classifying consultations into first, second, and follow-up visits, with a specific daily number, and giving more time to the first 2 types of consultations.</div></div><div><h3>Conclusion</h3><div>Although this planning implies greater effort on the part of administrative staff, it will undoubtedly result in a better quality of care for rheumatology patients.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"32 1","pages":"Pages 84-89"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139879923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Características de los pacientes reumáticos que consultan fuentes de información digitales","authors":"Maria Pía Izaguirre Germain ,&nbsp;Paola Ávila ,&nbsp;Nauan Fara ,&nbsp;Julia Pretini ,&nbsp;María Elena Gaona ,&nbsp;Pia Pissani ,&nbsp;Maira Arias Saavedra ,&nbsp;Valeria Aquino ,&nbsp;Mariana Espindola Echazu ,&nbsp;Manuela Laffont ,&nbsp;Magdalena Acevedo ,&nbsp;Lucrecia Garcia Faura ,&nbsp;Romina Hassan ,&nbsp;Karen Roberts ,&nbsp;Jorge Alejandro Brigante ,&nbsp;Damaris Álvarez ,&nbsp;Marina Laura Micelli ,&nbsp;Vanesa Laura Cosentino ,&nbsp;Sandra Fabiana Montoya ,&nbsp;Gabriel Sequeira ,&nbsp;Eduardo Mario Kerzberg","doi":"10.1016/j.rcreu.2023.11.007","DOIUrl":"10.1016/j.rcreu.2023.11.007","url":null,"abstract":"<div><h3>Introduction</h3><div>Many patients use the Internet as a source of health information and to create and share content of diverse quality of evidence, complementing and even competing with traditional sources of information.</div></div><div><h3>Objectives</h3><div>To evaluate differences between rheumatic patients who consult digital information sources (DISs) and those who do not (Non-DISs), and their perception of the credibility attributed to these sources by both groups.</div></div><div><h3>Materials and methods</h3><div>An observational cross-sectional study was conducted through an anonymous survey of patients with rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, and spondyloarthritis. Patients were asked about their search for information from different DISs or Non-DISs. Patients rated the credibility they assigned to the different sources on a scale of 0 to 10, where 0 was no credibility and 10 was the maximum possible credibility.</div></div><div><h3>Results</h3><div>A total of 402 patients (79% female) were surveyed. Two hundred and 7<!--> <!-->(51%) had consulted at least one DIS during the previous year (DISs group). The DISs group had consulted a total of 5 DISs and Non-DISs (First-Third Quartile: 3-7) vs. 2 (First-Third Quartile: 1-3) in the Non-DISs group (p&lt;<!--> <!-->.001). The number of searches in DISs was higher at younger ages (OR .97 95% CI .95-.99) and at higher levels of education (secondary vs. primary OR 2.0; 95% CI 1.05-3.85). The DISs group assigned higher credibility to Facebook and YouTube than the other patients (median credibility of 6/10 and 6/10 vs. 2/10 and 1/10 respectively; <em>P</em>&lt;.001). However, they did not assign lower credibility to traditional sources.</div></div><div><h3>Conclusions</h3><div>DISs are more frequently consulted by a younger population with a higher level of education. These patients consult multiple sources, but do not assign lower credibility to traditional information sources.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"32 1","pages":"Pages 43-48"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139883063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hallazgos histológicos y complicaciones en pacientes con biopsia de glándula salival en dos instituciones de Medellín, Colombia: estudio descriptivo","authors":"Luz Adriana Gómez-Ramírez ,&nbsp;Laura Betancur-Gómez ,&nbsp;Estefanía Tabares-Ramírez ,&nbsp;Sofía Villada-Montoya ,&nbsp;Libia María Rodríguez-Padilla ,&nbsp;María Fernanda Álvarez-Barreneche ,&nbsp;Carlos Jaime Velásquez-Franco ,&nbsp;Miguel Antonio Mesa-Navas ,&nbsp;Marcela Posada-Velásquez","doi":"10.1016/j.rcreu.2023.10.005","DOIUrl":"10.1016/j.rcreu.2023.10.005","url":null,"abstract":"<div><h3>Introduction</h3><div>Salivary gland biopsy is the gold standard for the diagnosis of Sjogren's syndrome. There are several approaches for the realization of the biopsy, being generally used an approach to the mucosa with the use of various instruments and incisions that vary in its length, passing through trucut biopsy to scraping with needle.</div></div><div><h3>Objective</h3><div>Evaluate the performance, complications and histological report systems of the minor salivary gland biopsy with a minimally invasive technique.</div></div><div><h3>Materials and methods</h3><div>We conducted a descriptive study that included adult patients undergoing salivary gland biopsy between 2017-2022. Medical records and salivary gland biopsy reports were used to collect information and registered in the Magpi platform. Sociodemographic, clinical, and histopathological variables were recorded. The qualitative variables were expressed in absolute and relative frequencies; the quantitative ones were by median and interquartile range. Seventy-two biopsies were included.</div></div><div><h3>Results</h3><div>Regarding demographic characteristics, 87,5% were women with a median age of 52 years. The biopsy characteristics showed that 70 (97,2%) corresponded to a representative sample. Twenty-seven (38,5%) biopsies showed lymphocytic infiltration and reported a classification system, of which the most used one was the Chisholm Mason used in 18 (66,6%) of such biopsies. Complications were present in four (5,7%) patients.</div></div><div><h3>Conclusions</h3><div>Despite the recommendation of using Focus Score for classification criteria, the Chisholm Mason system is still the most widely used. The present technique is a safe and effective for the realization of minor salivary gland biopsy.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"32 1","pages":"Pages 3-9"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139634928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}