Revista Colombiana de Reumatologia最新文献

{"title":"El citomegalovirus como modulador profibrótico en esclerosis sistémica: evidencia experimental","authors":"Victoria E. Butrón-Verástegui, José M. Vela-Ruiz, Sacha Barrios Healey","doi":"10.1016/j.rcreu.2026.504913","DOIUrl":"10.1016/j.rcreu.2026.504913","url":null,"abstract":"","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 3","pages":"Article 504913"},"PeriodicalIF":0.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148660569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inyección intraarticular de glucocorticoides guiada por ultrasonido. Una revisión sistemática de la literatura","authors":"Luis Pereira Sarduy,&nbsp;Alida Ricardo Marzo","doi":"10.1016/j.rcreu.2026.504920","DOIUrl":"10.1016/j.rcreu.2026.504920","url":null,"abstract":"<div><div>Ultrasound-guided intra-articular glucocorticoid (IA-GC) injection has transformed local management of various rheumatic diseases by improving procedural accuracy and safety. This systematic review analyzed evidence published between 2010 and 2024 on the efficacy, safety, optimal dosing, and controversies surrounding ultrasound-guided IA-GC, including original articles, systematic reviews, meta-analyses, and clinical practice guidelines. The studies showed that ultrasound guidance significantly increased injection accuracy (86.7% vs 26.7% with landmark guidance; p &lt; 0.05) and reduced procedural pain by 48% (VAS: 3.0<!--> <!-->±<!--> <!-->2.8<!--> <!-->cm vs 5.8<!--> <!-->±<!--> <!-->3.0<!--> <!-->cm; p &lt; 0.001). It also improved short-term therapeutic outcomes (VAS at 2 weeks: 1.5<!--> <!-->±<!--> <!-->1.9<!--> <!-->cm vs 2.8<!--> <!-->±<!--> <!-->2.4<!--> <!-->cm; p = 0.034), with significant improvements in pain and joint function. In knee osteoarthritis, pain reduction (VAS) was approximately 4.4 points (95% CI: 4.1-4.7), with a short-term success rate of 78.6%. In the acromioclavicular joint, ultrasound guidance yielded greater pain relief (mean difference [MD] 1.9, 95% CI: 1.2-2.6; p &lt; 0.00001) and functional improvement (Constant score MD 10.9, 95% CI: 6.57-15.23; p &lt; 0.00001) compared with landmark-guided injection. The most supported regimen was triamcinolone 40<!--> <!-->mg for large joints and 10-20<!--> <!-->mg for small joints, although dosing varied considerably. Serious complications were uncommon, but systematic safety assessment was insufficient. Ultrasound-guided IA-GC is a valuable tool, although multicenter, standardized studies are needed to strengthen clinical recommendations.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 3","pages":"Article 504920"},"PeriodicalIF":0.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148660566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex hormones in psoriasis and psoriatic arthritis: Unraveling a complex immunoendocrine dialogue","authors":"Daniela B. Tovar-Bastidas,&nbsp;Enrique R. Soriano","doi":"10.1016/j.rcreu.2026.504964","DOIUrl":"10.1016/j.rcreu.2026.504964","url":null,"abstract":"","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 3","pages":"Article 504964"},"PeriodicalIF":0.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148647387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Renal ultrasound in rheumatic diseases","authors":"Fabiola Pazos-Pérez,&nbsp;Carlos Enrique Méndez-Landa,&nbsp;María Ines Gil-Arredondo,&nbsp;Yessyca López-Cabrera,&nbsp;Estefanía Garduño-Hernández,&nbsp;Francisco Román Soto-Zuñiga,&nbsp;Ivan Jese Casas-Romero,&nbsp;Jesús Iván Lara-Prado,&nbsp;Dulce Paola Grajales-García","doi":"10.1016/j.rcreu.2026.504931","DOIUrl":"10.1016/j.rcreu.2026.504931","url":null,"abstract":"<div><div>Ultrasound (US) is the imaging study of choice in patients with systemic autoimmune rheumatic diseases with clinical suspicion of kidney damage, as it requires no radiation, is non-invasive, and provides real-time imaging. It has become more accessible, and currently, bedside US can be performed with portable devices. US allows evaluation of the structural (shape and size) and functional (perfusion and permeability) aspects of the kidneys, which are particularly important as rheumatological diseases progress. There are no specific ultrasonographic findings in these diseases; consequently, interpretation often depends on clinical correlation. This review describes the most frequent indications and findings in conventional US and Doppler US in various systemic rheumatological diseases.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 3","pages":"Article 504931"},"PeriodicalIF":0.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148660571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep quality in rheumatoid arthritis: A cross sectional study","authors":"Sonia Rekik,&nbsp;Faïza Ben Messaoud,&nbsp;Safa Rahmouni,&nbsp;Khaoula Zouaoui,&nbsp;Lobna Ben Ammar,&nbsp;Maïssa Abbes,&nbsp;Soumaya Boussaid,&nbsp;Hela Sahli","doi":"10.1016/j.rcreu.2025.04.002","DOIUrl":"10.1016/j.rcreu.2025.04.002","url":null,"abstract":"<div><h3>Introduction</h3><div>While numerous studies have examined the physical consequences of rheumatoid arthritis (RA), its impact on sleep quality remains relatively understudied.</div></div><div><h3>Objective</h3><div>This study aims to specifically assess the effect of RA on patients’ sleep quality.</div></div><div><h3>Materials and methods</h3><div>We conducted a cross-sectional study. Patient characteristics were assessed. The patients’ sleep quality was assessed using the Medical Outcomes Study Sleep Scale (MOS-Sleep scale) in its validated Arabic version.</div></div><div><h3>Results</h3><div>The study included <em>n</em> <!-->=<!--> <!-->49 patients with RA. Their mean age was 54.1<!--> <!-->±<!--> <span>12.06 years [24–83]. The mean diagnostic delay was 2.35 years [.5–13]. The RA was erosive in 46 cases (93.8%), two patients (4.1%) had atlantoaxial subluxation, and coxitis was noted in four cases (8.2%). A longer diagnostic delay was associated with a higher sleep problem index score. A significant positive association was found between VAS pain and all sleep disturbance scores (</span><em>p</em> <!-->=<!--> <!-->.00 and <em>r</em> <!-->=<!--> <!-->.518). The presence of comorbidities was associated with a higher index (<em>p</em> <!-->=<!--> <span>.03). This was also true in case of coxitis and/or atlantoaxial subluxation (</span><em>p</em> <!-->=<!--> <span>.03). For therapeutic management, we did not find a statistically significant association between the use of NSAIDs or corticosteroids, or methotrexate (MTX), and the sleep problem index. However, weekly dosage of MTX was positively correlated with the sleep problem index (</span><em>p</em> <!-->=<!--> <!-->.03, <em>r</em> <!-->=<!--> <!-->.358). The multivariate analysis found global patient assessment (GPA) (<em>p</em> <!-->=<!--> <!-->.000), presence of comorbidities (<em>p</em> <!-->=<!--> <span>.007), and presence of atlantoaxial subluxation and/or coxitis (</span><em>p</em> <!-->=<!--> <!-->.05) were significant factors influencing sleep quality.</div></div><div><h3>Conclusion</h3><div>Diagnostic delay and the global management of RA patients, including co-morbidities could impact sleep quality. Therefore, early treatment and holistic management of patients are necessary.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 3","pages":"Article 102184"},"PeriodicalIF":0.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148647391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the potential link between vitamin D receptor Cdx2 gene polymorphism and rheumatoid arthritis in female patients: A study in Erbil, Kurdistan Region-Iraq","authors":"Raghda R. Qadir,&nbsp;Bushra H. Shnawa,&nbsp;Mukhtar H. Ahmed","doi":"10.1016/j.rcreu.2025.03.004","DOIUrl":"10.1016/j.rcreu.2025.03.004","url":null,"abstract":"<div><h3>Introduction</h3><div>In recent decades, vitamin D has been extensively researched in relation to several autoimmune diseases, including Rheumatoid Arthritis (RA).</div></div><div><h3>Objective</h3><div>The primary objective of this study is to investigate the relationship between RA and polymorphism in vitamin D receptor gene Cdx2 in a sample of women.</div></div><div><h3>Methods</h3><div>Eighty females (60 with RA and 20 controls) participated in this case–control investigation. The Cdx2 single nucleotide polymorphism (SNP) of the VDR gene was genotyped using the tetra-primer amplification refractory mutation system-polymerase chain reaction technique (ARMS-PCR).</div></div><div><h3>Results</h3><div>The current study found that 51 RA patients have the heterozygous GA genotype of the Cdx2 polymorphism despite non-significant values. Although the present findings showed no significant association between Cdx2 gene polymorphism and the risk of RA, this genotype still represents the majority among the study's RA patients. Moreover, vitamin D3 serum was significantly lower in RA with the GA genotype compared to healthy controls (HC) with a similar genotype (<em>p</em> <!-->=<!--> <!-->.0002). Also, RA patients with heterozygote GA genotype for Cdx2 had a relatively lower mean VD3 serum level than those with homozygote GG genotype.</div></div><div><h3>Conclusion</h3><div>The novelty of this study is to discover the probable association of Vitamin D receptor, caudal-related homeobox<span> 2 (VDR-Cdx2) polymorphism with RA in the given study group for the first time in our society using a tetra primer ARMS-PCR. Additionally, the tetra-primer ARMS-PCR technique is simple, reliable, and cost-effective, making it a potentially valuable alternative to Restriction Fragment Length Polymorphism-Polymerase Chain Reaction (RFLP-PCR) for (SNP) genotyping.</span></div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 3","pages":"Article 102179"},"PeriodicalIF":0.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148647397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The cultural adaptation, reliability and validity of the Turkish version of the Maastricht Social Participation Profile questionnaire in patients with rheumatoid arthritis","authors":"Aylin Cicekli,&nbsp;Saniye Yardim,&nbsp;Sebahat Yaprak Cetin,&nbsp;Atif Cicekli,&nbsp;Ayse Ayan","doi":"10.1016/j.rcreu.2026.504888","DOIUrl":"10.1016/j.rcreu.2026.504888","url":null,"abstract":"<div><h3>Introduction</h3><div>Social participation of individuals with chronic physical disabilities is crucial because it examines their processes of integration, which contributes to the identification of their quality of life, inclusion in life situations, and processes of discrimination.</div></div><div><h3>Objective</h3><div>This study aimed to investigate the validity and reliability of the Turkish version of the Maastricht Social Participation Profile (MSPP) in patients with rheumatoid arthritis (RA).</div></div><div><h3>Materials and methods</h3><div>The study involved experts in consulting who evaluated the scale's content validity after retrospective translation into Turkish. The sample consisted of 130 volunteer patients diagnosed with RA by a rheumatologist. The reliability and validity of the scale used in the research was examined with confirmatory factor analysis (CFA), the Cronbach's alpha coefficient. The Cronbach alpha reliability coefficients were calculated to test the internal consistency and reliability of scales. Also, intraclass correlation coefficient (ICC) was used to evaluate the consistency or reproducibility of the scale.</div></div><div><h3>Results</h3><div>The MSPP research data showed an acceptable fit in terms of goodness-of-fit index values. Structural differences emerged in all sub-dimensions, with the modified MSPP Cronbach's alpha calculated at 0.86 for the total scale.</div></div><div><h3>Conclusion</h3><div>In conclusion, the Turkish version of the MSPP is valid, reliable, and appropriate tool for evaluating the social participation of RA patients. This study aims to fill the gap in the evaluation of social participation among chronic illness patients with RA in Turkey. By developing a scale for this purpose, it is expected to provide valuable guidance for future research.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 3","pages":"Article 504888"},"PeriodicalIF":0.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148647396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of lung ultrasound in connective tissue disease associated interstitial lung disease","authors":"Esther Vicente-Rabaneda,&nbsp;Maria Carolina Torres,&nbsp;Pedro Santos-Moreno,&nbsp;Julia Recalde-Reyes,&nbsp;Wilder Carvajal-Gutierrez","doi":"10.1016/j.rcreu.2026.504876","DOIUrl":"10.1016/j.rcreu.2026.504876","url":null,"abstract":"<div><div>Pulmonary involvement is a common manifestation of various rheumatologic diseases, significantly impacting prognosis. Early diagnosis is crucial, and the recent use of bedside ultrasound by clinicians has opened new diagnostic avenues. This review explores the current state of the art regarding rheumatologic diseases and their ultrasound representation.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 3","pages":"Article 504876"},"PeriodicalIF":0.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148647285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on ultrasound in crystal arthropathies","authors":"Alessandro Lucia,&nbsp;Jairo Cajamarca,&nbsp;Rodolfo Fabbri,&nbsp;Georgios Filippou,&nbsp;Mario Díaz","doi":"10.1016/j.rcreu.2026.504875","DOIUrl":"10.1016/j.rcreu.2026.504875","url":null,"abstract":"<div><div>Crystal-induced arthropathies (CIAs), which include gout, calcium pyrophosphate deposition (CPPD) disease, and basic calcium phosphate deposition (BCPD) disease, are prevalent yet intricate conditions characterized by the deposition of specific crystal types in joints and periarticular tissues. While synovial fluid analysis using polarized light microscopy remains a cornerstone for diagnosis, musculoskeletal ultrasound (US) has emerged as a highly sensitive, non-invasive diagnostic modality for the evaluation of CIAs. The capability of ultrasound to produce real-time, high-resolution, and dynamic imaging positions it as an invaluable tool in the assessment and management of these disorders. In recent years, US has been rigorously studied and validated for its diagnostic accuracy and reliability, particularly in gout and CPPD. Its sensitivity in detecting features such as the double contour sign in gout and CPP aggregates in fibrocartilage and hyaline cartilage in case of CPPD has been well-documented. Conversely, while US is frequently utilized in BCPD for diagnostic purposes, monitoring disease progression, and guiding imaging-assisted procedures, a robust and comprehensive validation of its utility in this condition remains lacking. This review underscores the role of ultrasound in the diagnosis and management of CIAs, with a focus on its applications in gout, CPPD, and BCPD. It discusses its clinical benefits and the current evidence supporting its use. Additionally, the review highlights gaps in research, particularly for BCPD, and outlines future directions to enhance the integration of ultrasound in the diagnostic and therapeutic landscape of CIAs.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 3","pages":"Article 504875"},"PeriodicalIF":0.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148647287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Eye of Horus” sign on ultrasound in a case of polymyalgia rheumatica","authors":"José S. Cortés,&nbsp;Diego Niño,&nbsp;Carlos Darío Ochoa Rojas","doi":"10.1016/j.rcreu.2026.504879","DOIUrl":"10.1016/j.rcreu.2026.504879","url":null,"abstract":"<div><h3>Introduction</h3><div>Ultrasound is useful in the assessment of polymyalgia rheumatica, a condition characterized by involvement of the shoulder and pelvic girdles. The “Eye of Horus” sign on ultrasound, corresponding to subacromial-subdeltoid bursitis and biceps brachii tenosynovitis, has been described in this patient.</div></div><div><h3>Case report</h3><div>A 70-year-old woman presented with pain and limitation in the shoulder and pelvic girdles, along with elevated acute-phase reactants. Ultrasound revealed the “Eye of Horus” sign. A diagnosis of polymyalgia rheumatica was made. She was treated with corticosteroids and methotrexate, showing improvement.</div></div><div><h3>Conclusion</h3><div>The “Eye of Horus” sign supports the diagnosis of polymyalgia rheumatica.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 3","pages":"Article 504879"},"PeriodicalIF":0.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148647288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}