Anemia hemolítica autoinmune por crioaglutininas asociado a lupus eritematoso sistémico. Presentación de casos y revisión de la literatura

Q3 Health Professions

Revista Colombiana de Reumatologia Pub Date : 2025-04-01 DOI:10.1016/j.rcreu.2024.02.003

Jaime Alberto Coral Enríquez , Victoria Eugenia Cajas Bravo

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Abstract

Introduction

Cold agglutinin autoimmune haemolytic anaemia (AIHA) secondary to systemic lupus erythematosus (SLE) is a rare manifestation. There are no cohorts or case series that allow us to evaluate the characteristics of this group of patients.

Objective

To describe the clinical and serological characteristics of patients with systemic lupus erythematosus (SLE) and cold agglutinin hemolytic anemia.

Materials and methods

We present two cases with SLE that debuted with cold agglutinin AHAI, their clinical and immunological profile and response to immunosuppressive treatment.

Results

Eleven cases reported in the literature from 1950 to 2023 are described.

Conclusion

Cold agglutinin AHAI secondary to SLE is rare, with similar clinical features compared to idiopathic forms and usually not associated with manifestations or serious organic involvement.

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与系统性红斑狼疮有关的低凝集素导致的自身免疫性溶血性贫血。病例报告和文献综述

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来源期刊

Revista Colombiana de Reumatologia Medicine-Rheumatology

CiteScore

0.80

自引率

0.00%

发文量

期刊介绍： The Colombian Journal of Rheumatology (Revista Colombiana de Reumatología) is the official organ of the Colombian Association of Rheumatology (Asociación Colombiana de Reumatología) and the Central American, Caribbean and Andean Association of Rheumatology (Asociación Centroamericana Caribe Andina de Reumatología) - ACCA. It was created in December 1993 with the purpose of disseminating scientific information derived from primary and secondary research and presenting cases coming from the practice of Rheumatology in Latin America. Since its foundation, the Journal has been characterized by its plurality with subjects of all rheumatic and osteomuscular pathologies, in the form of original articles, historical articles, economic evaluations, and articles of reflection and education in Medicine. It covers an extensive area of topics ranging from the broad spectrum of the clinical aspects of rheumatology and related areas in autoimmunity (both in pediatric and adult pathologies), to aspects of basic sciences. It is an academic tool for the different members of the academic and scientific community at their different levels of training, from undergraduate to post-doctoral degrees, managing to integrate all actors inter and trans disciplinarily. It is intended for rheumatologists, general internists, specialists in related areas, and general practitioners in the country and abroad. It has become an important space in the work of all rheumatologists from Central and South America.