Revista Colombiana de Reumatologia最新文献

{"title":"Ultrasonographic evaluation of nail involvement in psoriatic arthritis: A systematic review and meta-analysis","authors":"Jairo Cajamarca-Barona ,&nbsp;Catalina Sanmiguel-Reyes ,&nbsp;Jhon Buitrago ,&nbsp;Laura Gallego ,&nbsp;Diana Guavita-Navarro ,&nbsp;Jose Yate ,&nbsp;Ana María Arredondo ,&nbsp;Hector Cubides ,&nbsp;Alejandro Escobar ,&nbsp;Adriana Rojas-Villarraga ,&nbsp;Diego Javier Martínez Lozano","doi":"10.1016/j.rcreu.2026.504877","DOIUrl":"10.1016/j.rcreu.2026.504877","url":null,"abstract":"<div><h3>Introduction and objective</h3><div>Nail involvement is a hallmark of psoriatic arthritis (PsA), often reflecting disease severity and systemic inflammation. Subclinical nail changes frequently precede joint symptoms, making early detection essential for timely intervention. Ultrasonography, with its high-frequency probes and power Doppler technology, provides a non-invasive method to assess nail structures and inflammatory activity. Our systematic review and meta-analysis concentrate on the role of ultrasound (US) in identifying subclinical or early PsA-related nail changes – particularly nail plate and nail bed thickness.</div></div><div><h3>Materials and methods</h3><div>A systematic review and meta-analysis were conducted following the PRISMA guidelines. Nine studies were included for qualitative synthesis, and three studies for quantitative meta-analysis. A comprehensive search of PubMed and EMBASE was performed using MeSH terms and keywords including “psoriatic arthritis,” “nail,” and “ultrasonography.” Random-effects models calculated pooled mean differences for nail thickness, and heterogeneity was assessed using the <em>I</em>² statistic.</div></div><div><h3>Results</h3><div>Among 253 participants (175 PsA, 78 controls), patients with PsA exhibited significantly increased nail plate thickness (mean difference: 0.11<!--> <!-->mm, 95% CI: 0.07–0.15, <em>p</em> <!-->&lt;<!--> <!-->0.001, <em>I</em>² <!-->=<!--> <!-->12%) and nail bed thickness (mean difference: 0.20<!--> <!-->mm, 95% CI: 0.14–0.26, <em>p</em> <!-->&lt;<!--> <!-->0.001, <em>I</em>² <!-->=<!--> <!-->18%). Ultrasonographic findings also revealed subclinical enthesitis and increased power Doppler signals indicative of active inflammation. Consistent results across studies highlight ultrasonography's diagnostic reliability.</div></div><div><h3>Conclusion</h3><div>Ultrasonography is a robust, non-invasive method for evaluating nail involvement in PsA, with increased nail plate and bed thickness serving as reliable markers of disease activity. Standardization of ultrasonographic protocols and further multicenter studies are recommended to validate these findings and expand their clinical application.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 504877"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vasculitis asociada a ANCAs con compromiso pulmonar severo como efecto adverso del propiltiouracilo. Reporte de caso","authors":"José S. Cortés ,&nbsp;Javier Alejandro Correa ,&nbsp;Wilder Carvajal ,&nbsp;Wilmer Aponte ,&nbsp;Luis Javier Cajas","doi":"10.1016/j.rcreu.2026.504866","DOIUrl":"10.1016/j.rcreu.2026.504866","url":null,"abstract":"<div><h3>Introduction</h3><div>Propylthiouracil (PTU) is used to treat Graves’ disease and has been reported to induce antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).</div></div><div><h3>Case report</h3><div>A 54-year-old woman with Graves’ disease developed PTU-associated AAV, manifested by diffuse alveolar hemorrhage complicated by pneumonia and pleural effusion. As part of her treatment, she received methylprednisolone, prednisolone, and rituximab. The patient showed remarkable pulmonary recovery at three-month follow-up.</div></div><div><h3>Conclusions</h3><div>This case highlights the importance of early recognition of PTU-induced AAV and the progression of a severe pulmonary complication.</div><div>.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 504866"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salivary gland ultrasound: From standard protocols to clinical impact in rheumatology","authors":"Karen Tatiana Gualdrón-Chaparro ,&nbsp;Juan David Urriago-Gil ,&nbsp;José Santiago Cortés Guzmán ,&nbsp;Sofia C. Barreira ,&nbsp;Santiago Bernal-Macías","doi":"10.1016/j.rcreu.2026.504873","DOIUrl":"10.1016/j.rcreu.2026.504873","url":null,"abstract":"<div><div>Ultrasound of the salivary and parotid glands has become a valuable tool in rheumatology, especially in the assessment of patients with sicca symptoms, including those with Sjögren's syndrome (SjS). This imaging modality offers a non-invasive approach with proven sensitivity for diagnosis, disease differentiation, and treatment response assessment. This article presents a comprehensive literature review on the use of salivary gland ultrasound (SGUS) in various conditions associated with sicca symptoms, focusing on its application in SjS and other diseases like sarcoidosis, IgG4-related disease (IgG4-RD), and amyloidosis. We summarize the SGUS protocol, normal and pathological findings, and the OMERACT scoring system that standardizes SGUS interpretation. Studies show SGUS provides significant diagnostic support in SjS, with potential utility in assessing other connective tissue and infiltrative diseases, although its role in non-SjS conditions remains under study. Further validation is needed to define its role in clinical algorithms, especially in non-SjS etiologies, and to establish its prognostic value in treatment response. SGUS may improve the sensitivity and specificity of established diagnostic criteria, though it does not entirely replace biopsy in certain cases. Future research should further validate SGUS in diverse rheumatic conditions.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 504873"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on ultrasound in spondyloarthritis and psoriatic arthritis","authors":"Sebastián Herrera Uribe ,&nbsp;Erika Marcela Padilla Martínez ,&nbsp;Diana Padilla-Ortiz ,&nbsp;Emilio Filippucci","doi":"10.1016/j.rcreu.2026.504871","DOIUrl":"10.1016/j.rcreu.2026.504871","url":null,"abstract":"<div><div>Musculoskeletal ultrasound has emerged as an important imaging modality in the diagnosis and management of spondyloarthritis and psoriatic disease offering detailed insights that help guide clinical decision-making and optimizing patient care. We aim to review its utility in diagnosis, treatment, prognosis and special situations in both diseases.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 504871"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guías de práctica clínica en Latinoamérica. La propuesta de Colombia","authors":"Jorge Rojas-Serrano","doi":"10.1016/j.rcreu.2026.504916","DOIUrl":"10.1016/j.rcreu.2026.504916","url":null,"abstract":"","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 504916"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guía de práctica clínica para el diagnóstico y el tratamiento de la enfermedad pulmonar intersticial asociada a esclerosis sistémica y artritis reumatoide en Colombia. Asociación Colombiana de Reumatología - Asoreuma y Asociación Colombiana de Neumología y Cirugía de Tórax - ASONEUMOCITO","authors":"Luis Javier Cajas ,&nbsp;Javier Leonardo Galindo ,&nbsp;Diana Gil ,&nbsp;Daniel G. Fernández-Ávila ,&nbsp;Yimy Medina ,&nbsp;Olga Milena García ,&nbsp;Ledys Blanquicett Barrios ,&nbsp;Rubén Darío Contreras ,&nbsp;Dolfus Santiago Romero ,&nbsp;Jorge Abella ,&nbsp;Ángela María Giraldo Montoya ,&nbsp;Sebastián Herrera ,&nbsp;July Vianneth Torres ,&nbsp;Ana Milena Callejas ,&nbsp;Andrés Ricardo Fernández Aldana ,&nbsp;Mauricio González García ,&nbsp;J. Guillermo López V. ,&nbsp;Carlos Eduardo Matiz ,&nbsp;Paul Méndez Patarroyo ,&nbsp;Uriel Panqueva ,&nbsp;Jorge Alberto Carrillo-Bayona","doi":"10.1016/j.rcreu.2025.504841","DOIUrl":"10.1016/j.rcreu.2025.504841","url":null,"abstract":"<div><h3>Objective</h3><div>To develop evidence-based recommendations for the screening, diagnosis, treatment, and follow-up of interstitial lung disease associated with systemic sclerosis (SSc-ILD) and rheumatoid arthritis (RA-ILD), applicable to current medical practice in Colombia.</div></div><div><h3>Methods</h3><div>A multidisciplinary team of rheumatologists, pulmonologists, and radiologists with expertise in interstitial lung diseases was convened by ASONEUMOCITO and Asoreuma to develop national clinical practice guidelines for SSc-ILD and RA-ILD. Using standardized processes for evidence review and appraisal, and following the GRADE methodology, recommendations were formulated based on the balance of benefits and risks, patient values and preferences, equity, and resource use.</div></div><div><h3>Results</h3><div>A total of 55 recommendations were developed for SSc-ILD and RA-ILD. These recommendations cover screening and diagnosis via clinical evaluation, pulmonary function tests, and high-resolution computed tomography (HRCT) of the chest. The first-line treatment for SSc-ILD includes immunosuppressive agents, while the first-line treatment for RA-ILD includes conventional synthetic disease-modifying antirheumatic drugs (csDMARDs). Depending on patient characteristics and prior treatment exposure, these may be followed by biological agents, JAK inhibitors, or antifibrotic therapies. Other interventions, such as lung or bone marrow transplantation, oxygen therapy, pulmonary rehabilitation, and palliative care, are considered in specific clinical scenarios. Regular follow-up is essential to detect disease progression and guide timely therapeutic decisions.</div></div><div><h3>Conclusions</h3><div>These guidelines—Colombia's first national recommendations for the management of SSc-ILD and RA-ILD—provide evidence-based guidance tailored to the country's healthcare context and available resources, aiming to promote comprehensive and high-quality care for patients affected by these conditions.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 504841"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rheumatologic ultrasound in neurologic diseases of the peripheral nerve","authors":"Catalina Sanmiguel-Reyes,&nbsp;Ruddy Paola Montoya Rumpf,&nbsp;María Paula Carrillo,&nbsp;Carol Anne Mayorga,&nbsp;Héctor Sierra,&nbsp;Sebastián Moreno,&nbsp;Ana Trujillo,&nbsp;Alejandro Escobar,&nbsp;Adriana Rojas-Villarraga,&nbsp;Jairo Cajamarca-Barón","doi":"10.1016/j.rcreu.2026.504874","DOIUrl":"10.1016/j.rcreu.2026.504874","url":null,"abstract":"<div><div>Ultrasonography (US) has become a pivotal tool in assessing peripheral nerve pathology, especially within the rheumatologic domain. Its ability to provide high-resolution, non-invasive imaging enhances diagnostic accuracy and guides therapeutic decisions in complex cases. This review synthesizes the applications, benefits, and limitations of ultrasound in the diagnosis and management of neurologic disorders affecting peripheral nerves in rheumatologic patients.</div><div>The main ultrasound findings in patients with peripheral nervous system involvement in rheumatic diseases are:<ul><li><span>-</span><span><div>Entrapment neuropathies: US effectively identifies characteristic changes such as increased cross-sectional areas and altered echogenicity in conditions like carpal tunnel and cubital tunnel syndromes, enabling early diagnosis and monitoring.</div></span></li><li><span>-</span><span><div>Inflammatory neuropathies: chronic inflammatory demyelinating polyneuropathy (CIDP) and anti-MAG antibody neuropathy demonstrate distinct ultrasonographic patterns, aiding differential diagnoses.</div></span></li><li><span>-</span><span><div>Trauma and neoplasms: ultrasound detects structural abnormalities such as nerve discontinuities, intraneural fibrosis, and nerve-associated tumors with high accuracy.</div></span></li></ul></div><div>US offers several advantages, including real-time dynamic assessments, cost-effectiveness, and non-invasiveness. However, its efficacy is highly dependent on operator expertise and may be limited in deeper nerve imaging.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 504874"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical manifestations, diagnosis, and management of otospondylomegaepiphyseal dysplasia (OSMED): A case report and literature review","authors":"Mohammad Reza Fathi ,&nbsp;Mohammad-Reza Mahmoudian-Sani","doi":"10.1016/j.rcreu.2025.03.003","DOIUrl":"10.1016/j.rcreu.2025.03.003","url":null,"abstract":"<div><div>The case involves a 16-year-old boy from Iran with various medical issues. He experiences morning pain in his knees, ankles, and limb deformity. His medical history revealed congenital deafness and a previous episode of fever and seizures. The boy's parents are related, and his 6-month-old sister, who had similar symptoms, passed away. Physical examination findings include short stature, shortened limbs, flexion contracture in the elbow joints, abnormalities such as enlarged knees and ankles, Pectus excavatum, short arms, protruding eyes, a flattened nose bridge, and finger deformities. X-ray results show enlarged joints, decreased thoracic vertebrae height, thoracic spine scoliosis, and thickened and fused wrist bones. Echocardiography and eye examination showed normal findings with no abnormalities, but audiometry revealed bilateral sensorineural hearing loss. Genetic testing confirmed a homozygous mutation in the COL11A2 gene, leading to a diagnosis of OSMED.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 102178"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comite Editorial online","authors":"","doi":"10.1016/S0121-8123(26)00041-1","DOIUrl":"10.1016/S0121-8123(26)00041-1","url":null,"abstract":"","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 504902"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Models and implementation of education in rheumatologic ultrasonography","authors":"Edgar Alfonso Peñaranda-Parada","doi":"10.1016/j.rcreu.2026.504870","DOIUrl":"10.1016/j.rcreu.2026.504870","url":null,"abstract":"<div><div>Learning in rheumatologic ultrasonography (RU) is a fundamental competence for the clinical practice of the rheumatologist, given its broad benefits for the timely diagnosis and effective treatment of patients, which are achieved immediately at the point of care. This paper argues that, for the appropriate training and construction of ultrasound skills, the structured design of a curricular plan is required, initially inspired by international experiences that managed to consolidate the formal teaching of RU in other latitudes. Subsequently, the implementation of a teaching model in ultrasound is described, supported by the constructivist theory in education, based on learning by competencies and formative evaluation through courses of increasing complexity, according to the particularities of the environment and with the active participation of all the actors in the process. Finally, a quality assurance model is described, which will integrate the subject to the recommendations of self-evaluation and accreditation of the regulatory entities in education.</div></div>","PeriodicalId":37643,"journal":{"name":"Revista Colombiana de Reumatologia","volume":"33 2","pages":"Article 504870"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147754253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}