Open Neuroimaging Journal最新文献_第5页

Primary Intracranial Choriocarcinoma Located in the Suprasellar Region. 原发性颅内绒毛膜癌位于鞍上区。

Open Neuroimaging Journal Pub Date : 2016-06-30 eCollection Date: 2016-01-01 DOI: 10.2174/1874440001610010080

Xiuli Li, Kazuhiro Murayama, Ayumi Watanabe, Masato Abe, Hiroshi Toyama

引用次数: 2

Long-Term (Six Years) Clinical Outcome Discrimination of Patients in the Vegetative State Could be Achieved Based on the Operational Architectonics EEG Analysis: A Pilot Feasibility Study. 基于操作架构脑电图分析的长期(六年)植物状态患者临床结果判别:一项试点可行性研究。

Open Neuroimaging Journal Pub Date : 2016-05-13 eCollection Date: 2016-01-01 DOI: 10.2174/1874440001610010069

Andrew A Fingelkurts, Alexander A Fingelkurts, Sergio Bagnato, Cristina Boccagni, Giuseppe Galardi

{"title":"Long-Term (Six Years) Clinical Outcome Discrimination of Patients in the Vegetative State Could be Achieved Based on the Operational Architectonics EEG Analysis: A Pilot Feasibility Study.","authors":"Andrew A Fingelkurts, Alexander A Fingelkurts, Sergio Bagnato, Cristina Boccagni, Giuseppe Galardi","doi":"10.2174/1874440001610010069","DOIUrl":"https://doi.org/10.2174/1874440001610010069","url":null,"abstract":"Electroencephalogram (EEG) recordings are increasingly used to evaluate patients with disorders of consciousness (DOC) or assess their prognosis outcome in the short-term perspective. However, there is a lack of information concerning the effectiveness of EEG in classifying long-term (many years) outcome in chronic DOC patients. Here we tested whether EEG operational architectonics parameters (geared towards consciousness phenomenon detection rather than neurophysiological processes) could be useful for distinguishing a very long-term (6 years) clinical outcome of DOC patients whose EEGs were registered within 3 months post-injury. The obtained results suggest that EEG recorded at third month after sustaining brain damage, may contain useful information on the long-term outcome of patients in vegetative state: it could discriminate patients who remain in a persistent vegetative state from patients who reach a minimally conscious state or even recover a full consciousness in a long-term perspective (6 years) post-injury. These findings, if confirmed in further studies, may be pivotal for long-term planning of clinical care, rehabilitative programs, medical-legal decisions concerning the patients, and policy makers. ","PeriodicalId":37431,"journal":{"name":"Open Neuroimaging Journal","volume":"10 ","pages":"69-79"},"PeriodicalIF":0.0,"publicationDate":"2016-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8c/0a/TONIJ-10-69.PMC4894941.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34613933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Challenges and Pitfalls Associated with Diagnostic and Prognostic Applications of Functional Neuroimaging in Disorders of Consciousness. 功能神经影像学在意识障碍诊断和预后应用中的挑战和缺陷。

Open Neuroimaging Journal Pub Date : 2016-05-13 eCollection Date: 2016-01-01 DOI: 10.2174/1874440001610010023

Yelena G Bodien, Joseph T Giacino

引用次数: 9

The Chief Role of Frontal Operational Module of the Brain Default Mode Network in the Potential Recovery of Consciousness from the Vegetative State: A Preliminary Comparison of Three Case Reports. 脑默认模式网络额叶操作模块在植物人意识潜在恢复中的主要作用:三例报告的初步比较。

Open Neuroimaging Journal Pub Date : 2016-05-13 eCollection Date: 2016-01-01 DOI: 10.2174/1874440001610010041

Alexander A Fingelkurts, Andrew A Fingelkurts, Sergio Bagnato, Cristina Boccagni, Giuseppe Galardi

{"title":"The Chief Role of Frontal Operational Module of the Brain Default Mode Network in the Potential Recovery of Consciousness from the Vegetative State: A Preliminary Comparison of Three Case Reports.","authors":"Alexander A Fingelkurts, Andrew A Fingelkurts, Sergio Bagnato, Cristina Boccagni, Giuseppe Galardi","doi":"10.2174/1874440001610010041","DOIUrl":"https://doi.org/10.2174/1874440001610010041","url":null,"abstract":"It has been argued that complex subjective sense of self is linked to the brain default-mode network (DMN). Recent discovery of heterogeneity between distinct subnets (or operational modules - OMs) of the DMN leads to a reconceptualization of its role for the experiential sense of self. Considering the recent proposition that the frontal DMN OM is responsible for the first-person perspective and the sense of agency, while the posterior DMN OMs are linked to the continuity of 'I' experience (including autobiographical memories) through embodiment and localization within bodily space, we have tested in this study the hypothesis that heterogeneity in the operational synchrony strength within the frontal DMN OM among patients who are in a vegetative state (VS) could inform about a stable self-consciousness recovery later in the course of disease (up to six years post-injury). Using EEG operational synchrony analysis we have demonstrated that among the three OMs of the DMN only the frontal OM showed important heterogeneity in VS patients as a function of later stable clinical outcome. We also found that the frontal DMN OM was characterized by the process of active uncoupling (stronger in persistent VS) of operations performed by the involved neuronal assemblies. ","PeriodicalId":37431,"journal":{"name":"Open Neuroimaging Journal","volume":"10 ","pages":"41-51"},"PeriodicalIF":0.0,"publicationDate":"2016-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/38/7e/TONIJ-10-41.PMC4894863.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34613932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

The Role of Neuroimaging in the Diagnosis, Prognosis and Management of Disorders of Consciousness and Locked-in Syndrome. 神经影像学在意识障碍和闭锁综合征的诊断、预后和治疗中的作用。

Open Neuroimaging Journal Pub Date : 2016-05-13 eCollection Date: 2016-01-01 DOI: 10.2174/1874440001610010020

Francesca Pistoia, Antonio Carolei

{"title":"The Role of Neuroimaging in the Diagnosis, Prognosis and Management of Disorders of Consciousness and Locked-in Syndrome.","authors":"Francesca Pistoia, Antonio Carolei","doi":"10.2174/1874440001610010020","DOIUrl":"https://doi.org/10.2174/1874440001610010020","url":null,"abstract":"Disorders of consciousness and locked-in syndrome are two completely different neurological conditions which share unresponsiveness or minimal responsiveness at an observable behavioral level. The key element of disorders of consciousness is the loss of self- and environmental awareness, while the main feature of locked-in syndrome is extreme motor entrapment despite preserved awareness. In both cases accurate diagnosis may come late and patients are at risk of being wrongly diagnosed and missing out on appropriate rehabilitative opportunities. Clinical assessment alone often does not suffice in establishing the correct diagnosis and prognosis. The contribution of advanced neuroimaging techniques is essential in order to properly recognize patients' conditions and formulate a tailored rehabilitative approach. Neuroimaging findings are also crucial in identifying the neuropathological substrate of the disorders: they contribute to elucidating the dynamics of cortical-subcortical networks in disorders of consciousness and the neural correlates of recently reported non-motor symptoms in locked-in syndrome. ","PeriodicalId":37431,"journal":{"name":"Open Neuroimaging Journal","volume":"10 ","pages":"20-2"},"PeriodicalIF":0.0,"publicationDate":"2016-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ae/f6/TONIJ-10-20.PMC4894861.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34612915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The Role of Neuroimaging Techniques in Establishing Diagnosis, Prognosis and Therapy in Disorders of Consciousness. 神经影像学技术在意识障碍诊断、预后和治疗中的作用。

Open Neuroimaging Journal Pub Date : 2016-05-13 eCollection Date: 2016-01-01 DOI: 10.2174/1874440001610010052

Olivia Gosseries, Francesca Pistoia, Vanessa Charland-Verville, Antonio Carolei, Simona Sacco, Steven Laureys

{"title":"The Role of Neuroimaging Techniques in Establishing Diagnosis, Prognosis and Therapy in Disorders of Consciousness.","authors":"Olivia Gosseries, Francesca Pistoia, Vanessa Charland-Verville, Antonio Carolei, Simona Sacco, Steven Laureys","doi":"10.2174/1874440001610010052","DOIUrl":"https://doi.org/10.2174/1874440001610010052","url":null,"abstract":"Non-communicative brain damaged patients raise important clinical and scientific issues. Here, we review three major pathological disorders of consciousness: coma, the unresponsive wakefulness syndrome and the minimally conscious state. A number of clinical studies highlight the difficulty in making a correct diagnosis in patients with disorders of consciousness based only on behavioral examinations. The increasing use of neuroimaging techniques allows improving clinical characterization of these patients. Recent neuroimaging studies using positron emission tomography, functional magnetic resonance imaging, electroencephalography and transcranial magnetic stimulation can help assess diagnosis, prognosis, and therapeutic treatment. These techniques, using resting state, passive and active paradigms, also highlight possible dissociations between consciousness and responsiveness, and are facilitating a more accurate understanding of brain function in this challenging population. ","PeriodicalId":37431,"journal":{"name":"Open Neuroimaging Journal","volume":"10 ","pages":"52-68"},"PeriodicalIF":0.0,"publicationDate":"2016-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/1874440001610010052","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34613934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 37

Disembodied Mind: Cortical Changes Following Brainstem Injury in Patients with Locked-in Syndrome. 无实体思维:闭锁综合征患者脑干损伤后的皮质变化。

Open Neuroimaging Journal Pub Date : 2016-05-13 eCollection Date: 2016-01-01 DOI: 10.2174/1874440001610010032

Francesca Pistoia, Riccardo Cornia, Massimiliano Conson, Olivia Gosseries, Antonio Carolei, Simona Sacco, Carlo C Quattrocchi, Carlo A Mallio, Cristina Iani, Debora Di Mambro, Marco Sarà

{"title":"Disembodied Mind: Cortical Changes Following Brainstem Injury in Patients with Locked-in Syndrome.","authors":"Francesca Pistoia, Riccardo Cornia, Massimiliano Conson, Olivia Gosseries, Antonio Carolei, Simona Sacco, Carlo C Quattrocchi, Carlo A Mallio, Cristina Iani, Debora Di Mambro, Marco Sarà","doi":"10.2174/1874440001610010032","DOIUrl":"https://doi.org/10.2174/1874440001610010032","url":null,"abstract":"Locked-in syndrome (LIS) following ventral brainstem damage is the most severe form of motor disability. Patients are completely entrapped in an unresponsive body despite consciousness is preserved. Although the main feature of LIS is this extreme motor impairment, minor non-motor dysfunctions such as motor imagery defects and impaired emotional recognition have been reported suggesting an alteration of embodied cognition, defined as the effects that the body and its performances may have on cognitive domains. We investigated the presence of structural cortical changes in LIS, which may account for the reported cognitive dysfunctions. For this aim, magnetic resonance imaging scans were acquired in 11 patients with LIS (6 males and 5 females; mean age: 52.3±5.2SD years; mean time interval from injury to evaluation: 9±1.2SD months) and 44 healthy control subjects matching patients for age, sex and education. Freesurfer software was used to process data and to estimate cortical volumes in LIS patients as compared to healthy subjects. Results showed a selective cortical volume loss in patients involving the superior frontal gyrus, the pars opercularis and the insular cortex in the left hemisphere, and the superior and medium frontal gyrus, the pars opercularis, the insular cortex, and the superior parietal lobule in the right hemisphere. As these structures are typically associated with the mirror neuron system, which represents the neural substrate for embodied simulation processes, our results provide neuroanatomical support for potential disembodiment in LIS. ","PeriodicalId":37431,"journal":{"name":"Open Neuroimaging Journal","volume":"10 ","pages":"32-40"},"PeriodicalIF":0.0,"publicationDate":"2016-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/1874440001610010032","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34613931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Does Congenital Deafness Affect the Structural and Functional Architecture of Primary Visual Cortex? 先天性耳聋会影响初级视觉皮层的结构和功能结构吗？

Open Neuroimaging Journal Pub Date : 2016-02-29 eCollection Date: 2016-01-01 DOI: 10.2174/1874440001610010001

C R Smittenaar, M MacSweeney, M I Sereno, D S Schwarzkopf

引用次数: 0

Arachnoiditis Ossificans - A Rare Cause of Progressive Myelopathy. 骨化性蛛网膜炎——进行性脊髓病的罕见病因。

Open Neuroimaging Journal Pub Date : 2015-08-31 eCollection Date: 2015-01-01 DOI: 10.2174/1874440001509010013

Christopher J Steel, Erik L Abrames, William T O'Brien

引用次数: 11

Experimental Fusion of Contrast Enhanced High-Field Magnetic Resonance Imaging and High-Resolution Micro-Computed Tomography in Imaging the Mouse Inner Ear. 对比增强高场磁共振成像和高分辨率微计算机断层扫描在小鼠内耳成像中的实验融合。

Open Neuroimaging Journal Pub Date : 2015-07-31 eCollection Date: 2015-01-01 DOI: 10.2174/1874440001509010007

S Allen Counter, Peter Damberg, Sahar Nikkhou Aski, Kálmán Nagy, Cecilia Engmér Berglin, Göran Laurell

{"title":"Experimental Fusion of Contrast Enhanced High-Field Magnetic Resonance Imaging and High-Resolution Micro-Computed Tomography in Imaging the Mouse Inner Ear.","authors":"S Allen Counter, Peter Damberg, Sahar Nikkhou Aski, Kálmán Nagy, Cecilia Engmér Berglin, Göran Laurell","doi":"10.2174/1874440001509010007","DOIUrl":"https://doi.org/10.2174/1874440001509010007","url":null,"abstract":"Objective: Imaging cochlear, vestibular, and 8th cranial nerve abnormalities remains a challenge. In this study, the membranous and osseous labyrinths of the wild type mouse inner ear were examined using volumetric data from ultra high-field magnetic resonance imaging (MRI) with gadolinium contrast at 9.4 Tesla and high-resolution micro-computed tomography (µCT) to visualize the scalae and vestibular apparatus, and to establish imaging protocols and parameters for comparative analysis of the normal and mutant mouse inner ear.Methods: For in vivo MRI acquisition, animals were placed in a Milleped coil situated in the isocenter of a horizontal 9.4 T Varian magnet. For µCT examination, cone beam scans were performed ex vivo following MRI using the µCT component of a nanoScan PET/CT in vivo scanner.Results: The fusion of Gd enhanced high field MRI and high-resolution µCT scans revealed the dynamic membranous labyrinth of the perilymphatic fluid filled scala tympani and scala vestibule of the cochlea, and semicircular canals of the vestibular apparatus, within the µCT visualized contours of the contiguous osseous labyrinth. The ex vivo µCT segmentation revealed the surface contours and structural morphology of each cochlea turn and the semicircular canals in 3 planes.Conclusions: The fusion of ultra high-field MRI and high-resolution µCT imaging techniques were complementary, and provided high-resolution dynamic and static visualization of the complex morphological features of the normal mouse inner ear structures, which may offer a valuable approach for the investigation of cochlear and vestibular abnormalities that are associated with birth defects related to genetic inner ear disorders in humans.","PeriodicalId":37431,"journal":{"name":"Open Neuroimaging Journal","volume":"9 ","pages":"7-12"},"PeriodicalIF":0.0,"publicationDate":"2015-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/91/21/TONIJ-9-7.PMC4578136.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34201788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9