Open Neuroimaging Journal最新文献_第6页

Hippocampal morphology in a rat model of depression: the effects of physical activity. 抑郁症大鼠模型的海马形态:体育活动的影响。

Open Neuroimaging Journal Pub Date : 2015-01-30 eCollection Date: 2014-01-01 DOI: 10.2174/1874440001509010001

Adam Sierakowiak, Anna Mattsson, Marta Gómez-Galán, Teresa Feminía, Lisette Graae, Sahar Nikkhou Aski, Peter Damberg, Mia Lindskog, Stefan Brené, Elin Åberg

{"title":"Hippocampal morphology in a rat model of depression: the effects of physical activity.","authors":"Adam Sierakowiak, Anna Mattsson, Marta Gómez-Galán, Teresa Feminía, Lisette Graae, Sahar Nikkhou Aski, Peter Damberg, Mia Lindskog, Stefan Brené, Elin Åberg","doi":"10.2174/1874440001509010001","DOIUrl":"https://doi.org/10.2174/1874440001509010001","url":null,"abstract":"Accumulating in vivo and ex vivo evidences show that humans suffering from depression have decreased hippocampal volume and altered spine density. Moreover, physical activity has an antidepressant effect in humans and in animal models, but to what extent physical activity can affect hippocampal volume and spine numbers in a model for depression is not known. In this study we analyzed whether physical activity affects hippocampal volume and spine density by analyzing a rodent genetic model of depression, Flinders Sensitive Line Rats (FSL), with Magnetic Resonance Imaging (MRI) and ex vivo Golgi staining. We found that physical activity in the form of voluntary wheel running during 5 weeks increased hippocampal volume. Moreover, runners also had larger numbers of thin spines in the dentate gyrus. Our findings support that voluntary wheel running, which is antidepressive in FSL rats, is associated with increased hippocampal volume and spine numbers. ","PeriodicalId":37431,"journal":{"name":"Open Neuroimaging Journal","volume":"9 ","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2015-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/1874440001509010001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33048749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

Increasing neuroradiology exam volumes on-call do not result in increased major discrepancies in primary reads performed by residents. 增加随叫随到的神经放射学检查量并不会导致住院医师进行的初级读数的主要差异增加。

Open Neuroimaging Journal Pub Date : 2015-01-27 eCollection Date: 2014-01-01 DOI: 10.2174/1874440001408010011

Jared T Verdoorn, Christopher H Hunt, Marianne T Luetmer, Christopher P Wood, Laurence J Eckel, Kara M Schwartz, Felix E Diehn, David F Kallmes

{"title":"Increasing neuroradiology exam volumes on-call do not result in increased major discrepancies in primary reads performed by residents.","authors":"Jared T Verdoorn, Christopher H Hunt, Marianne T Luetmer, Christopher P Wood, Laurence J Eckel, Kara M Schwartz, Felix E Diehn, David F Kallmes","doi":"10.2174/1874440001408010011","DOIUrl":"https://doi.org/10.2174/1874440001408010011","url":null,"abstract":"Background and purpose: A common perception is that increased on-call workload leads to increased resident mistakes. To test this, we evaluated whether increased imaging volume has led to increased errors by residents.Materials and methods: A retrospective review was made of all overnight neuroradiology CT exams with a primary resident read from 2006-2010. All studies were over-read by staff neuroradiologists next morning. As the volume is higher on Friday through Sunday nights, weekend studies were examined separately. Discrepancies were classified as either minor or major. \"Major\" discrepancy was defined as a discrepancy that the staff radiologist felt was significant enough to potentially affect patient care, necessitating a corrected report and phone contact with the ordering physician and documentation. The total number of major discrepancies was recorded by quarter. In addition, the total number of neuroradiology CT studies read overnight on-call was noted.Results: The mean number of cases per night during the weekday increased from 3.0 in 2006 to 5.2 in 2010 (p<0.001). During the weekend, the mean number of cases per night increased from 5.4 in 2006 to 7.6 in 2010 (p<0.001). Despite this increase, the major discrepancy rate decreased from 2.7% in 2006 to 2.3% in 2010 (p=0.34).Conclusion: Despite an increase in neuroradiology exam volumes, there continues to be a low major discrepancy rate for primary resident interpretations. While continued surveillance of on-call volumes is crucial to the educational environment, concern of increased major errors should not be used as sole justification to limit autonomy.","PeriodicalId":37431,"journal":{"name":"Open Neuroimaging Journal","volume":"8 ","pages":"11-5"},"PeriodicalIF":0.0,"publicationDate":"2015-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f5/a2/TONIJ-8-11.PMC4311384.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33023823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Enhanced power within the default mode network in normal subjects with elevated scores on an egocentric scale. 自我中心量表得分较高的正常受试者默认模式网络内的权力增强。

Open Neuroimaging Journal Pub Date : 2014-11-19 eCollection Date: 2014-01-01 DOI: 10.2174/1874440001408010005

Mark W G Collins, Michael A Persinger

引用次数: 6

A schizophrenia-like psychotic disorder secondary to an arachnoid cyst remitted with neurosurgical treatment of the cyst. 蛛网膜囊肿一种继发于蛛网膜囊肿的精神分裂症样精神障碍，通过神经外科治疗囊肿得以缓解。

Open Neuroimaging Journal Pub Date : 2014-02-21 eCollection Date: 2014-01-01 DOI: 10.2174/1874440001408010001

G A Baquero, P Molero, J Pla, F Ortuño

引用次数: 19

Benign Notochordal Cell Tumor of the Sacrum with Atypical Imaging Features: The Value of CT Guided Biopsy for Diagnosis. 影像特征不典型的骶骨良性脊索细胞瘤:CT引导活检的诊断价值。

Open Neuroimaging Journal Pub Date : 2013-12-30 eCollection Date: 2013-01-01 DOI: 10.2174/1874440001307010036

Dario Pasalic, Patrick H Luetmer, Christopher H Hunt, Peter S Rose, Felix E Diehn, Andrew L Folpe, Doris E Wenger

引用次数: 14

CASE REPORT: MENINGIOMA WITH INTRA-TUMOURAL HAEMORRHAGE SECONDARY TO RUPTURED DISTAL ANTERIOR CEREBRAL ARTERY ANEURYSM 病例报告:脑膜瘤合并肿瘤内出血继发于脑前远端动脉瘤破裂

Open Neuroimaging Journal Pub Date : 2013-12-30 DOI: 10.2174/1874440001307010035

引用次数: 0

Neural substrates underlying learning-related changes of the unconditioned fear response. 非条件恐惧反应学习相关变化的神经基础。

Open Neuroimaging Journal Pub Date : 2013-12-30 eCollection Date: 2013-01-01 DOI: 10.2174/1874440001307010041

Kimberly H Wood, Dystany Kuykendall, Lawrence W Ver Hoef, David C Knight

{"title":"Neural substrates underlying learning-related changes of the unconditioned fear response.","authors":"Kimberly H Wood, Dystany Kuykendall, Lawrence W Ver Hoef, David C Knight","doi":"10.2174/1874440001307010041","DOIUrl":"https://doi.org/10.2174/1874440001307010041","url":null,"abstract":"The ability to predict an impending threat during Pavlovian conditioning diminishes the emotional response that is produced once the threat is encountered. Diminution of the threat response appears to be mediated by somewhat independent associative learning and expectancy-related processes. Therefore, the present study was designed to better understand the neural mechanisms that support associative learning processes, independent of expectancy, that influence the emotional response to a threat. Healthy volunteers took part in a Pavlovian conditioning procedure during which trait anxiety, expectation of the unconditioned stimulus (UCS), skin conductance response (SCR), and functional magnetic resonance imaging (fMRI) signal were assessed. The results showed no evidence for associative learning that was independent of expectation. Threat-related SCR expression was diminished on predictable trials vs. unpredictable trials of the UCS (i.e. conditioned UCR diminution). Similar to SCR, conditioned UCR diminution was observed within the left dorsolateral PFC, dorsomedial PFC, ventromedial PFC, and left anterior insula. In contrast, potentiation of the threat-related fMRI signal response was observed within left dorsolateral PFC, inferior parietal lobule (IPL), and posterior insula. A negative relationship was observed between UCS expectancy and UCR expression within the dorsomedial PFC, ventromedial PFC, and anterior insula. Finally, the anticipatory fMRI signal responses within the PFC, posterior cingulate, and amygdala showed an inverse relationship with threat-related activation within the brain regions that showed UCR diminution. The current findings suggest that the PFC and amygdala support learning-related processes that impact the magnitude of the emotional response to a threat.","PeriodicalId":37431,"journal":{"name":"Open Neuroimaging Journal","volume":"7 ","pages":"41-52"},"PeriodicalIF":0.0,"publicationDate":"2013-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/71/13/TONIJ-7-41.PMC3905352.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32074985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Bottom-up Retinotopic Organization Supports Top-down Mental Imagery. 自下而上的视网膜组织支持自上而下的心理意象。

Open Neuroimaging Journal Pub Date : 2013-12-30 eCollection Date: 2013-01-01 DOI: 10.2174/1874440001307010058

Ruey-Song Huang, Martin I Sereno

{"title":"Bottom-up Retinotopic Organization Supports Top-down Mental Imagery.","authors":"Ruey-Song Huang, Martin I Sereno","doi":"10.2174/1874440001307010058","DOIUrl":"https://doi.org/10.2174/1874440001307010058","url":null,"abstract":"Finding a path between locations is a routine task in daily life. Mental navigation is often used to plan a route to a destination that is not visible from the current location. We first used functional magnetic resonance imaging (fMRI) and surface-based averaging methods to find high-level brain regions involved in imagined navigation between locations in a building very familiar to each participant. This revealed a mental navigation network that includes the precuneus, retrosplenial cortex (RSC), parahippocampal place area (PPA), occipital place area (OPA), supplementary motor area (SMA), premotor cortex, and areas along the medial and anterior intraparietal sulcus. We then visualized retinotopic maps in the entire cortex using wide-field, natural scene stimuli in a separate set of fMRI experiments. This revealed five distinct visual streams or 'fingers' that extend anteriorly into middle temporal, superior parietal, medial parietal, retrosplenial and ventral occipitotemporal cortex. By using spherical morphing to overlap these two data sets, we showed that the mental navigation network primarily occupies areas that also contain retinotopic maps. Specifically, scene-selective regions RSC, PPA and OPA have a common emphasis on the far periphery of the upper visual field. These results suggest that bottom-up retinotopic organization may help to efficiently encode scene and location information in an eye-centered reference frame for top-down, internally generated mental navigation. This study pushes the border of visual cortex further anterior than was initially expected. ","PeriodicalId":37431,"journal":{"name":"Open Neuroimaging Journal","volume":"7 ","pages":"58-67"},"PeriodicalIF":0.0,"publicationDate":"2013-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7f/a4/TONIJ-7-58.PMC3905356.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32074987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 40

Bilateral temporal bone langerhans cell histiocytosis: radiologic pearls. 双侧颞骨朗格汉斯细胞组织细胞增多症:放射学上的珍珠。

Open Neuroimaging Journal Pub Date : 2013-12-30 eCollection Date: 2013-01-01 DOI: 10.2174/1874440001307010053

Mira A Coleman, Jane Matsumoto, Carrie M Carr, Laurence J Eckel, Amulya A Nageswara Rao

引用次数: 23

Case Report: Meningioma with Intra-tumoural Haemorrhage Secondary to Ruptured Distal Anterior Cerebral Artery Aneurysm. 病例报告:脑膜瘤合并肿瘤内出血继发于脑前远端动脉瘤破裂。

Open Neuroimaging Journal Pub Date : 2013-10-18 eCollection Date: 2013-01-01 DOI: 10.2174/1874440001307010032

Ibrahim Alnaami, Ping Ho, Jian-Qiang Lu, Blaise Wheatley

{"title":"Case Report: Meningioma with Intra-tumoural Haemorrhage Secondary to Ruptured Distal Anterior Cerebral Artery Aneurysm.","authors":"Ibrahim Alnaami, Ping Ho, Jian-Qiang Lu, Blaise Wheatley","doi":"10.2174/1874440001307010032","DOIUrl":"https://doi.org/10.2174/1874440001307010032","url":null,"abstract":"Background: Brain tumours that are associated with cerebral aneurysms are rare occurrences, whereas the coexistence of brain tumours and intra-tumoural aneurysms is even rarer. There have been 12 brain tumour cases that have been reported in the literature that describe an aneurysm within a brain tumour, with 4 of these tumours being meningiomas.Case description: A 34-year-old male patient presented with sudden-onset headache, and an inter-hemispheric meningioma with intra-tumoural bleeding was found due to a ruptured embedded anterior cerebral artery aneurysm. The aneurysm was diagnosed incidentally on the third cerebral angiogram, while the initial 2 angiograms were negative. The patient was treated with endovascular aneurysm embolisation that was followed by tumour resection.Conclusion: This paper is the first case report to describe the coexistence of a meningioma and an aneurysm, which presented with intra-tumoural haemorrhage that was negative on the initial cerebral angiogram. Unlike previous case reports, the aneurysm in this case was located with an anterior cerebral artery distribution.","PeriodicalId":37431,"journal":{"name":"Open Neuroimaging Journal","volume":"7 ","pages":"32-4"},"PeriodicalIF":0.0,"publicationDate":"2013-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2d/7a/TONIJ-7-32.PMC3812785.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31824633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10