European Journal of Obstetrics and Gynecology and Reproductive Biology: X最新文献

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Transvaginal natural orifice transluminal endoscopic surgery (vNOTES) in gynecological emergencies 经阴道自然孔腔内窥镜手术(vNOTES)在妇科急诊
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2023-11-21 DOI: 10.1016/j.eurox.2023.100261
Rafael Ferro , Yannick Hurni , Stéphanie Seidler , Daniela Huber
{"title":"Transvaginal natural orifice transluminal endoscopic surgery (vNOTES) in gynecological emergencies","authors":"Rafael Ferro ,&nbsp;Yannick Hurni ,&nbsp;Stéphanie Seidler ,&nbsp;Daniela Huber","doi":"10.1016/j.eurox.2023.100261","DOIUrl":"https://doi.org/10.1016/j.eurox.2023.100261","url":null,"abstract":"<div><h3>Objective</h3><p>Transvaginal natural orifice transluminal endoscopic surgery (vNOTES) is an emerging minimally invasive approach increasingly applied to perform many gynecological procedures. Despite a still limited level of evidence, compared to conventional laparoscopy, vNOTES seems to be associated with reduced blood loss, shorter operative time, less postoperative pain, shorter hospitalization time, better cosmetic results and decreased postoperative morbidity. Although growing evidence supports the effectiveness of vNOTES for elective adnexal surgeries, there is still limited knowledge regarding its feasibility and safety in emergency settings. In the present study, we report our experience performing vNOTES in gynecological emergency cases.</p></div><div><h3>Study design</h3><p>We prospectively collected and analyzed data from patients who underwent vNOTES for gynecological emergencies between November 2021 and June 2023. Demographic and perioperative characteristics were collected and analyzed.</p></div><div><h3>Results</h3><p>Seventeen patients were included. Interventions were realized for suspicion of ectopic pregnancy in 7 cases (41.2%), for suspicion of adnexal torsion in 7 cases (41.2%), for post-hysterectomy hemoperitoneum in 2 cases (11.8%), and for uncontrollable uterine bleeding in 1 case (5.9%). Emergency procedures included unilateral salpingectomy (35.3%), ovarian cystectomy (23.5%), ovarian cystotomy (17.6%), adnexal detorsion (11.8%), hemoperitoneum drainage (11.8%), hysterectomy (5.9%), and appendectomy (5.9%). The overall median operative time was 38 [18–72] minutes. The median estimated intraoperative blood loss was 30 [5−150] mL, and no intraoperative complications occurred. Conversion to conventional laparoscopy or laparotomy was never needed. Patients stayed hospitalized for a median time of 30 [4−144] hours after the intervention. The median visual analog scale value for postoperative pain evaluation was 2 [0−5] at 12, 24, and 48 postoperative hours. No complications associated with the procedure occurred.</p></div><div><h3>Conclusions</h3><p>This study demonstrated the feasibility of performing vNOTES procedures for managing gynecological emergencies such as tubal ectopic pregnancy, adnexal torsion, painful ovarian lesions, post-hysterectomy hemoperitoneum, and uncontrollable uterine bleeding. Associated with data reported in the available literature, our results suggest potential benefits in treating gynecological emergencies by vNOTES over conventional laparoscopy. However, stronger evidence from larger studies is needed to confirm it.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161323000868/pdfft?md5=eeac0ea831b35ff28f79a35bc4d660f5&pid=1-s2.0-S2590161323000868-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138412814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An algorithm for the pre-operative differentiation of benign ovarian tumours based on magnetic resonance imaging interpretation in a regional core hospital: A retrospective study 一种基于区域核心医院磁共振成像解释的良性卵巢肿瘤术前鉴别算法:回顾性研究
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2023-11-15 DOI: 10.1016/j.eurox.2023.100260
Wataru Isono, Hiroko Tsuchiya, Reiko Matsuyama, Akihisa Fujimoto, Osamu Nishii
{"title":"An algorithm for the pre-operative differentiation of benign ovarian tumours based on magnetic resonance imaging interpretation in a regional core hospital: A retrospective study","authors":"Wataru Isono,&nbsp;Hiroko Tsuchiya,&nbsp;Reiko Matsuyama,&nbsp;Akihisa Fujimoto,&nbsp;Osamu Nishii","doi":"10.1016/j.eurox.2023.100260","DOIUrl":"https://doi.org/10.1016/j.eurox.2023.100260","url":null,"abstract":"<div><h3>Objective</h3><p>For selecting minimally invasive surgery (i.e. laparoscopic ovarian cystectomy) for treating ovarian tumours (OTs) in premenopausal patients, the pre-operative differentiation of benign ovarian tumours (Be-OTs) based on magnetic resonance imaging (MRI) interpretation is important. This paper describes the authors’ 8-year experience of approximately 1000 OT cases, and provides information about a diagnostic algorithm to help other hospitals.</p></div><div><h3>Study design</h3><p>The medical records of 901 patients aged &lt; 50 years with OTs from 1 January 2015–31 March 31 2023 were reviewed. First, the accuracy of pre-operative differentiation between Be-OTs and borderline/malignant ovarian tumours (Bo/Ma-OTs) was compared in each type of OT. Second, to identify the factors influencing differentiation between Be-OTs and Bo/Ma-OTs in 164 serous/mucinous ovarian tumours (SM-OTs), a multi-variate logistic regression analysis was performed to assess the effect of 13 factors, including MRI findings, OT size and tumour markers.</p></div><div><h3>Results</h3><p>In the comparison of diagnostic accuracy of pre-operative MRI for each OT type, accuracy was found to be notably high for ovarian endometrial cyst (OEC) (<em>n</em> = 409), ovarian mature cystic teratoma (OMCT) (<em>n</em> = 308), ovarian endometrioid adenocarcinoma (OEA) (<em>n</em> = 6) and ovarian clear cell adenocarcinoma (OCCA) (<em>n</em> = 14). On the other hand, discrepancies between MRI and pathological findings often occurred in SM-OTs, including ovarian serous cystadenoma (<em>n</em> = 86), ovarian mucinous adenocarcinoma (<em>n</em> = 61), ovarian serous adenocarcinoma (<em>n</em> = 12) and ovarian mucinous adenocarcinoma (<em>n</em> = 5). In the multi-variate logistic regression analysis of the latter 164 patients, in addition to MRI findings, OT size and carbohydrate antigen 125 also had an effect to some extent. The combination of MRI interpretation and OT size may enhance differentiation of Be-OTs and Bo/Ma-OTs.</p></div><div><h3>Conclusions</h3><p>Among four types of OTs (OEC, OMCT, OEA and OCCA), MRI interpretation was able to differentiate between Be-OTs and Bo/Ma-OTs almost perfectly. Additionally, to mitigate the difficulty in differentiating SM-OTs, OT size may be useful in combination with MRI findings, although further accumulation and analysis of OT cases is needed.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161323000856/pdfft?md5=86c51186215b2d6fb3b1ad4e34f0ba3a&pid=1-s2.0-S2590161323000856-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138423059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomarker screening in fetal growth restriction based on multiple RNA-seq studies 基于多重RNA-seq研究的胎儿生长受限生物标志物筛选。
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2023-10-31 DOI: 10.1016/j.eurox.2023.100259
Xiaohui Li , Xin He , Zhengpeng Li , Yi Chen
{"title":"Biomarker screening in fetal growth restriction based on multiple RNA-seq studies","authors":"Xiaohui Li ,&nbsp;Xin He ,&nbsp;Zhengpeng Li ,&nbsp;Yi Chen","doi":"10.1016/j.eurox.2023.100259","DOIUrl":"10.1016/j.eurox.2023.100259","url":null,"abstract":"<div><h3>Objective</h3><p>Fetal growth restriction (FGR) is a severe pathological complication associated with compromised fetal development. The early diagnosis and prediction for FGR are still unclear. Sequencing technologies present a huge opportunity to identify novel biomarkers. However, limitation of individual studies (e.g., long lists of dysregulated genes, small sample size and conflicting results) hinders the selection of the best-matched ones.</p></div><div><h3>Study design</h3><p>A multi-step bioinformatics analysis was performed. We separately reanalyzed data from four public RNA-seq studies, followed by a combined analysis of individual results. The differentially expressed genes (DEGs) were identified based on DESeq2. Then, function enrichment analyses and protein-protein interaction network (PPI) were conducted to screen for hub genes. The results were further verified by using external microarray data.</p></div><div><h3>Results</h3><p>A total of 65 dysregulated genes (50 down and 15 upregulated) were identified in FGR compared to controls. Function enrichment and PPI analysis revealed ten hub genes closely related to FGR. Validation analysis found four downregulated candidate biomarkers (<em>CEACAM6</em>, <em>SCUBE2</em>, <em>DEFA4</em>, and <em>MPO</em>) for FGR.</p></div><div><h3>Conclusions</h3><p>The use of omics tools to explore mechanism of pregnancies disorders contributes to improvements in obstetric clinical practice.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89719882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High pre-pregnancy body mass index and gestational weight gain among women belonging to upper SES from Delhi, India 来自印度德里的高SES女性的高孕前体重指数和妊娠期体重增加。
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2023-10-21 DOI: 10.1016/j.eurox.2023.100258
Priyanka Arora , Bani Tamber Aeri
{"title":"High pre-pregnancy body mass index and gestational weight gain among women belonging to upper SES from Delhi, India","authors":"Priyanka Arora ,&nbsp;Bani Tamber Aeri","doi":"10.1016/j.eurox.2023.100258","DOIUrl":"10.1016/j.eurox.2023.100258","url":null,"abstract":"<div><h3>Background and objective</h3><p>With increase in prevalence of obesity and an increasing trend in the birth of macrosomic infants, Institute of Medicine (IOM) guidelines pertaining to optimal gestational weight gain (GWG) required for positive pregnancy outcome were revised in 1990 and 2009. Since, in the Indian scenario, no recommendations exist for optimum GWG for obese (OB) and overweight (OW) women, we assessed the pattern of GWG w.r.t Institute of Medicine (IOM), 2009 among the subjects with different body mass index (BMI).</p></div><div><h3>Study design</h3><p>Present data were a part of a longitudinal observational study wherein, 312 pregnant women (≤12th week of gestation) attending private antenatal clinics were followed till term and their weight was monitored regularly at pre-determined intervals i.e., 12th–14th, 18th–20th, 24th–26th, 30th–32nd, 36th + week of gestation and compared w.r.t IOM guidelines 2009.</p></div><div><h3>Results</h3><p>66.37 %, 57.89 % and 11.69 % of OB, OW and normal weight (NW) subjects respectively had weight gain exceeding their GWG limits. About 5 %,10.53 %, 33.77 % of OB, OW and NW subjects respectively had gained weight less than GWG limits (p = 0.000***).</p></div><div><h3>Conclusion</h3><p>An increase in GWG inadequacy with increase in BMI and pronounced variations in GWG among OB and OW subjects underscore the necessity to monitor GWG especially among the subjects with high BMI.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10628650/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71522772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is the central complement component C3 altered in the synergy of HIV infection and preeclampsia? 在HIV感染和先兆子痫的协同作用中,中心补体成分C3是否发生了改变?
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2023-10-20 DOI: 10.1016/j.eurox.2023.100257
Mikyle David, Shoohana Singh, Thajasvarie Naicker
{"title":"Is the central complement component C3 altered in the synergy of HIV infection and preeclampsia?","authors":"Mikyle David,&nbsp;Shoohana Singh,&nbsp;Thajasvarie Naicker","doi":"10.1016/j.eurox.2023.100257","DOIUrl":"https://doi.org/10.1016/j.eurox.2023.100257","url":null,"abstract":"<div><h3>Objective</h3><p>In light of complement activation in preeclampsia and HIV infection, this study evaluates the concentration of complement component 3 (C3) in HIV-associated preeclampsia.</p></div><div><h3>Method</h3><p>The study population (n = 76) was equally stratified by pregnancy type (normotensive pregnant and preeclampsia) and by HIV status (HIV positive and HIV negative). The plasma concentration of C3 was determined using a Bioplex immunoassay procedure.</p></div><div><h3>Results</h3><p>We report a significant increase in C3 concentration in the HIV-negative <em>versus</em> the HIV-positive groups (<em>p &lt;</em> 0.05), regardless of pregnancy type. However, based on pregnancy type and irrespective of HIV status, C3 concentration was similar between normotensive <em>versus</em> preeclampsia. Concentration of C3 was significantly increased in the HIV-positive preeclamptic compared HIV-negative preeclamptic groups (<em>p</em> = 0.04). The correlation of C3 with all study groups was non-significant.</p></div><div><h3>Conclusion</h3><p>This study demonstrates that C3 was upregulated in HIV-associated PE compared to HIV- associated normotensive pregnancies. The dysregulation of C3 expression by HIV infection may be attributed to antiretroviral therapy.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49778054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preconception laparoscopic cervical cerclage for prevention of mid-trimester pregnancy loss and preterm birth: A 6-year study 孕前腹腔镜宫颈环切术预防中期妊娠丢失和早产:一项为期6年的研究
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2023-10-20 DOI: 10.1016/j.eurox.2023.100256
Niraj Yanamandra, Swapna Pooskuru
{"title":"Preconception laparoscopic cervical cerclage for prevention of mid-trimester pregnancy loss and preterm birth: A 6-year study","authors":"Niraj Yanamandra,&nbsp;Swapna Pooskuru","doi":"10.1016/j.eurox.2023.100256","DOIUrl":"https://doi.org/10.1016/j.eurox.2023.100256","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate surgical results and pregnancy outcomes of preconception laparoscopic cervical cerclage (LCC) in women with cervical insufficiency.</p></div><div><h3>Study design</h3><p>We conducted an observational study in consecutive women who had preconception LCC. Data was prospectively collected from 55 women at high risk of second trimester miscarriage and extreme preterm delivery due to cervical insufficiency who underwent pre-conception LCC between January 2017 – December 2021. This included patient demographics and relevant obstetric &amp; gynaecological history, previous cervical cerclage, operative complications and subsequent pregnancy outcomes. All women included in study had at least one previous unsuccessful transvaginal cervical cerclage. The surgeries were conducted in private tertiary hospital in Hyderabad, India. The follow-up was until December 2022. The primary outcome was neonatal survival. Surgical morbidity and complications were also recorded.</p></div><div><h3>Results</h3><p>There were 49 pregnancies of which 46 progressed beyond first trimester. 4.34 % (2/46) were delivered between 28 and 33 weeks due to preterm premature rupture of membranes (PPROM). 13.04 % (6/46) including 5 women with pregnancy complications and one with unicornuate uterus needed delivery between 34 and 36 weeks. 82.60 % (38/46) women were delivered at or beyond 37 weeks of pregnancy. In those who carried pregnancy beyond first trimester, live-birth rate and neonatal survival rate were 100 %. All neonates had favourable outcome with no long-term morbidity. There were no intraoperative or immediate postoperative complications. Two women had long-term complication in the form of tape erosion needing further surgery.</p></div><div><h3>Conclusions</h3><p>This study provides evidence that LCC improves pregnancy outcomes significantly in those with cervical weakness, without increasing the safety risk.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161323000819/pdfft?md5=9d9017b8b420a42e460efdd105d38142&pid=1-s2.0-S2590161323000819-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92044498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effectiveness of aromatherapy in the management of labor pain: A meta-analysis 芳香疗法在分娩疼痛管理中的有效性:荟萃分析。
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2023-10-18 DOI: 10.1016/j.eurox.2023.100255
Atike Kaya , Havva Yeşildere Sağlam , Engin Karadağ , Elif Gürsoy
{"title":"The effectiveness of aromatherapy in the management of labor pain: A meta-analysis","authors":"Atike Kaya ,&nbsp;Havva Yeşildere Sağlam ,&nbsp;Engin Karadağ ,&nbsp;Elif Gürsoy","doi":"10.1016/j.eurox.2023.100255","DOIUrl":"10.1016/j.eurox.2023.100255","url":null,"abstract":"<div><p>One non-pharmacological method that can be used to safely and without negative side effects is aromatherapy. This meta-analysis study was carried out to assess the effectiveness of aromatherapy in the treatment of labor pain. The analysis included 14 randomized controlled trials of aromatherapy interventions for labor pain. In the studies, it was observed that aromatherapy was applied through massage and inhalation using oils such as lavender, jasmine, rose, chamomile, bitter orange, and boswellia. In the meta-analysis, it was discovered that aromatherapy had a beneficial effect on the management of labor pain and reduced labor pain in the intervention group in 11 studies; it was found that there was no effect in 3 studies. According to analysis findings, aromatherapy significantly lessened the intensity of labor pain. The study's findings support the notion that aromatherapy can lessen labor pain.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10632671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89719883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical features and outcomes of patients with preeclampsia and eclampsia at Gondar University hospital, Amhara, Ethiopia 2021 2021年埃塞俄比亚阿姆哈拉贡达尔大学医院先兆子痫和子痫患者的临床特征和预后
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2023-10-12 DOI: 10.1016/j.eurox.2023.100254
Tamalew Alemie , Asmamaw Abebe , Ousman Adal , Aklilu Azazh , Destaw Endeshaw
{"title":"Clinical features and outcomes of patients with preeclampsia and eclampsia at Gondar University hospital, Amhara, Ethiopia 2021","authors":"Tamalew Alemie ,&nbsp;Asmamaw Abebe ,&nbsp;Ousman Adal ,&nbsp;Aklilu Azazh ,&nbsp;Destaw Endeshaw","doi":"10.1016/j.eurox.2023.100254","DOIUrl":"https://doi.org/10.1016/j.eurox.2023.100254","url":null,"abstract":"<div><h3>Objective</h3><p>The aim of this study was to investigate the clinical features, and treatment outcome of women with preeclampsia and eclampsia at Gondar University Comprehensive Specialized Hospital in Amhara, Northern Ethiopia, in 2021.</p></div><div><h3>Methods</h3><p>An institutional-based retrospective chart review was conducted at Gondar University Specialized Hospital from March to June 2021. The study participants were chosen using a simple, systematic random sampling method. A pretested check list was used to collect data from medical records. The collected data was coded, entered into Epi-data version 4.6, and exported to SPSS version 26 for descriptive and inferential analysis. A Fisher’s exact test was used to determine statistically significant factors at a p-value of &lt; 0.05.</p></div><div><h3>Results</h3><p>Of the 311 study participants, more than half (53 %) of mothers have illiterate, nearly half (49.8 %) had preeclampsia with severe features. Eclampsia accounted for 18.6 % of females in the study setting. For various reasons, more than half of the mothers required immediate intervention to terminate the pregnancy via cesarean section. Unfavorable maternal outcomes were present in more than 25 % of cases; the observed unfavorable maternal outcomes were aspiration pneumonia (10.6 %), hemolytic elevated liver function test and low platelet count syndrome (8.7 %), and maternal death (0.6 %). The severity of the disease, mode of delivery, aspartate transaminase, gravidity, gestational age, and antenatal care were all statistically significant predictors of pregnancy outcome.</p></div><div><h3>Conclusion</h3><p>The prevalence of unfavorable maternal and perinatal outcomes of preeclampsia and eclampsia is considerable in the study area. To prevent these perinatal and postnatal effects, maternal outcomes of pregnancy, antenatal care services, emergency obstetrics, and new born care should be expanded and strengthened.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49790905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence of postpartum depression after treatment of postpartum anaemia with intravenous ferric carboxymaltose, intravenous ferric derisomaltose or oral ferrous sulphate: A randomized clinical trial 静脉注射羧麦芽糖铁、静脉注射脱体铁或口服硫酸亚铁治疗产后贫血后产后抑郁的发生率:一项随机临床试验
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2023-10-12 DOI: 10.1016/j.eurox.2023.100247
Lea Bombač Tavčar , Hana Hrobat , Lea Gornik , Vislava Globevnik Velikonja , Miha Lučovnik
{"title":"Incidence of postpartum depression after treatment of postpartum anaemia with intravenous ferric carboxymaltose, intravenous ferric derisomaltose or oral ferrous sulphate: A randomized clinical trial","authors":"Lea Bombač Tavčar ,&nbsp;Hana Hrobat ,&nbsp;Lea Gornik ,&nbsp;Vislava Globevnik Velikonja ,&nbsp;Miha Lučovnik","doi":"10.1016/j.eurox.2023.100247","DOIUrl":"https://doi.org/10.1016/j.eurox.2023.100247","url":null,"abstract":"<div><h3>Objectives</h3><p>This study aimed to explore whether the type of iron preparation used to treat postpartum anaemia affects the incidence of postpartum depression and whether the risk of postpartum depression is higher in postpartum patients with anaemia who were adequately treated compared to the general postpartum population.</p></div><div><h3>Study design</h3><p>Single-center, open-label, randomized trial. Women were allocated to receive intravenous ferric carboxymaltose, intravenous ferric derisomaltose or oral ferrous sulphate. Intravenous iron was given in one or two doses, while ferrous sulphate as two 80 mg tablets once daily. Primary outcome was postpartum depression measured by Edinburgh Postnatal Depression Scale (EPDS) six weeks postpartum. Haematological parameters were analyzed as secondary outcomes. Kruskal-Wallis test was used for group comparison (p &lt; 0.05 significant). The chi-square test was applied to compare categorical variables as well as the group of all subjects treated for anaemia in the study with the historical data for the Slovenian postpartum population.</p></div><div><h3>Results</h3><p>Three-hundred women with postpartum anemia (hemoglobin &lt; 100 g/L within 48-hours postpartum) were included between September 2020 and March 2022 in tertiary perinatal center. Most characteristics were similar across groups. EPDS score at six weeks postpartum did not differ between groups. The treatment modality of postpartum anaemia did not have a statistically significant effect on the EPDS score six weeks after treatment (p = 0.10), nor did it have a statistically significant effect on the difference in EPDS scores before and after treatment (p = 0.68). The proportions of participants who scored 10 or more points on the EPDS scores at six weeks postpartum were not statistically different between the groups (p = 0.79). The proportion of participants with an EPDS score of 10 or more at six weeks postpartum in the total study population did not differ significantly from previously reported proportion of postpartum women with EPDS score of 10 or more in the general population (12 % vs. 21 %; p &lt; 0.001).</p></div><div><h3>Conclusions</h3><p>Maternal depression at 6 weeks postpartum did not differ in women treated for postpartum anemia with intravenous ferric carboxymaltose, intravenous ferric derisomaltose or oral ferrous sulphate. Participants with postpartum anaemia who are adequately treated with either oral or intravenous iron preparations are not at a higher risk of postpartum depression than the general population at six weeks postpartum.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49819065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of antenatal care satisfaction amongst postpartum women at the University College Hospital, Ibadan, Nigeria 尼日利亚伊巴丹大学学院医院产后妇女产前护理满意度评估
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2023-10-12 DOI: 10.1016/j.eurox.2023.100252
Opeyemi Adeniyi Adedeji , Timothy A.O. Oluwasola , Funmilola Margaret Adedeji
{"title":"Assessment of antenatal care satisfaction amongst postpartum women at the University College Hospital, Ibadan, Nigeria","authors":"Opeyemi Adeniyi Adedeji ,&nbsp;Timothy A.O. Oluwasola ,&nbsp;Funmilola Margaret Adedeji","doi":"10.1016/j.eurox.2023.100252","DOIUrl":"https://doi.org/10.1016/j.eurox.2023.100252","url":null,"abstract":"<div><h3>Background</h3><p>Maternal mortality is unacceptably high especially in developing countries. About 287,000 women died during and following pregnancy and childbirth in 2020. The vast majority of these deaths (95 %) occurred in low and lower middle countries in 2020 and most could have been prevented. Every day in 2020, approximately 800 women died from preventable causes related to pregnancy and childbirth. Utilization of antenatal visit has been shown to improve birth outcome as well as the maternal outcome during pregnancy-related events, giving a positive impact when the visit frequency and care are adequate while satisfaction has equally been an important outcome measures of quality of care. In order to improve feto-maternal outcome and turn the tide against maternal deaths, it is expedient to assess the satisfaction of women who had experienced antenatal care with the aim of identifying areas requiring additional attention.</p></div><div><h3>Objective</h3><p>This study aimed to assess the level of antenatal care satisfaction of postpartum women and factors associated with satisfaction at the University College Hospital (UCH), Ibadan and their future intention for subsequent utilization of antenatal care.</p></div><div><h3>Methods</h3><p>A descriptive cross-sectional study of 261 women in the postnatal ward using simple random sampling technique was conducted with an interviewer-administered structured questionnaire. Items in the questionnaire included sociodemographic and obstetric variables, assessment of quality of amenities, waiting time and level of satisfaction. Data was entered, cleaned and analyzed by computer using the Statistical Package for Social Sciences Version 23.0 (SPSS, IBM). The variables were summarized using frequencies, proportions, means and standard deviation. Chi Square was used for test of significance with the p-value set at P &lt; 0.05.</p></div><div><h3>Results</h3><p>Of the 261 participants 176 (67.5 % percent) were aged 25–34 years; majority (244,93.5 %) had tertiary education while (189, 72.4 %) were skilled workers or professionals. Most of the women (243, 93.2 %) were Para 1–3 and the pregnancy was planned (80.8 %) while financing was mostly out of pocket (60.9 %). Only one-third of the participants has at least eight (8) antenatal contacts. In overall rating, most women (90.0 %) were satisfied with the antenatal care services received. The highest rating of satisfaction was with the competence of the service providers (90.4 %) especially with the care given to them and their unborn babies (90.4 %). The parity, distance of their home from antenatal clinic, number of antenatal contacts, number of health education sessions attended, total time spent, attitude of health workers, cost of services and desire to register again at the facility were statistically associated with patient’s satisfaction. Also, the number of antenatal visits was statistically associated with the fetal outcome.</p></div><div><h3>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49790904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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