European Journal of Obstetrics and Gynecology and Reproductive Biology: X最新文献

{"title":"Escalating caesarean deliveries and the impact on subsequent preterm birth","authors":"Laura van der Krogt,&nbsp;Agnieszka Glazewska-Hallin,&nbsp;Natalie Suff,&nbsp;Lisa Story,&nbsp;Andrew Shennan","doi":"10.1016/j.eurox.2025.100391","DOIUrl":"10.1016/j.eurox.2025.100391","url":null,"abstract":"<div><div>The rate of caesarean section, including those performed in-labour, is on the rise. Worldwide 1 in 5 women are delivering by caesarean section. Emerging evidence has demonstrated an association between in-labour caesarean section and mid-trimester loss (delivery between 14 and 24 weeks gestation) as well as spontaneous preterm birth, (delivery before 37 weeks’ gestation). This problem is more likely to recur in subsequent pregnancies and is difficult to treat with evidence suggesting that transvaginal cerclage may be a less efficacious preventative measure in women with a short cervix and previous in-labour caesarean section. This review explores the scope of the issue including the evidence for in-labour caesarean section as a risk factor for preterm birth and the possible underlying mechanism. It will discuss management strategies, as well as highlighting areas where further research is required.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"26 ","pages":"Article 100391"},"PeriodicalIF":1.5,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143891119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between different types and characteristics of fetal deceleration during labour and neonatal acidemia at delivery: A case-control study","authors":"Maria Fogelberg ,&nbsp;Charlotte Dahlbäck ,&nbsp;Frida Ekengård ,&nbsp;Gisela Rickle ,&nbsp;Andreas Herbst","doi":"10.1016/j.eurox.2025.100389","DOIUrl":"10.1016/j.eurox.2025.100389","url":null,"abstract":"<div><h3>Objective</h3><div>Classification of fetal heart rate (FHR) decelerations as suspicious or pathological differs between current interpretation templates for intrapartum cardiotocography. Decelerations are the most frequent FHR pattern irregularities during labour. The aim of this study was to assess the association between different types and characteristics of decelerations and acidemia at birth.</div></div><div><h3>Methods</h3><div>This case-control study includes 365 cases with cord pH &lt; 7.10 after 1st stage cesarean delivery or pH &lt; 7.05 after vaginal delivery at &gt; 34 + 0 weeks after induced or spontaneous labour, and 730 controls with pH ≥ 7.15. Cardiotocographic recordings from 60 min before birth were scrutinized and decelerations evaluated in detail. Odds ratios (OR) with 95 % confidence intervals for acidemia at birth were determined.</div></div><div><h3>Results</h3><div>The following types of decelerations were associated with acidemia: Late decelerations; OR 9.0 (6.1–13) if &gt; 5, and OR 19 (9.7–37) if repetitive &gt; 20 min, combined decelerations; OR 4.2 (2.7–6.4) if &gt; 5 and OR 6.4 (3.1–13) if repetitive &gt; 20 min, one prolonged deceleration &gt; 5 min; OR 12 (7.9–19), three prolonged decelerations for 3–5 min; OR 10 (4.3–25), and &gt; 5 variable decelerations &gt; 60 s; OR 2.2 (1.6–2.9). For variable decelerations &gt; 60 s, absent variability within decelerations was the only additional characteristic significantly associated with acidemia; OR 5.8 (2.1–16). A strong association with acidemia was noted for a FHR below the baseline ≥ 50 % of the time &gt; 30 min; OR 14 (10−19).</div></div><div><h3>Conclusion</h3><div>Late and prolonged decelerations are strongly, and combined decelerations moderately associated with acidemia. The risk of acidemia is highly increased if FHR is below baseline ≥ 50 % of the time.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"26 ","pages":"Article 100389"},"PeriodicalIF":1.5,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143886598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation the therapeutic effect of mindfulness-based cognitive-behavioral counseling in pregnant women with body image dissatisfaction: A randomized controlled trial","authors":"Mehnoosh Farahabadi ,&nbsp;Abbas Amanollahi ,&nbsp;Bahman Cheraghian ,&nbsp;Zahra Abbaspoor","doi":"10.1016/j.eurox.2025.100387","DOIUrl":"10.1016/j.eurox.2025.100387","url":null,"abstract":"<div><h3>Background and aims</h3><div>Dissatisfaction with body image during pregnancy is a common issue in the general population and can pose risks for both the mother and the child. The aim of this study was to investigate the therapeutic effect of mindfulness-based cognitive-behavioral counseling in pregnant women with body image dissatisfaction: A randomized controlled trial.</div></div><div><h3>Methods</h3><div>In this study, 50 pregnant women who were over 26 weeks pregnant were randomly assigned to intervention and control groups. In the intervention group, Mindfulness-based cognitive behavioral therapy was taught to pregnant women over 8 consecutive sessions, while the control group received no intervention. Body image concerns questionnaire was completed by both groups before and after the intervention, and data were analyzed using descriptive statistics and multivariate analysis of covariance.</div></div><div><h3>Results</h3><div>The results showed that before the intervention, the mean and standard deviation of body image concern scores in the intervention group was 58.36 ± 3.13 and in the control group, was 58.08 ± 3.31, but after the end of the intervention, in the intervention group it decreased to 41.40 ± 2.85 (p &lt; 0.001), while in the control group, it decreased (57.64 ± 3.42) slightly (P = 0.951). The total scores for body image concern in the intervention group were significantly lower compared to the control group (p &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>Mindfulness-based cognitive behavioral therapy can help reduce body image concerns in pregnant women. Therefore, it is recommended that mental health professionals utilize this approach to improve the psychological and physical well-being of pregnant women and assist them in modifying their attitudes towards body image.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"26 ","pages":"Article 100387"},"PeriodicalIF":1.5,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143834917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extragenital endometriosis associated with uterine scar defects","authors":"Tilman Born,&nbsp;Katrin Krejci,&nbsp;Maximilian Rauh,&nbsp;Georgia Cole,&nbsp;Maurice Kappelmeyer,&nbsp;Mehmet Vural ,&nbsp;Angela Köninger","doi":"10.1016/j.eurox.2025.100386","DOIUrl":"10.1016/j.eurox.2025.100386","url":null,"abstract":"<div><h3>Introduction</h3><div>Uterine scar defects result from poor healing of the hysterotomy after cesarean sections (CS), in multiple cases leading to retroflexio uteri and retrograde menstruation. Endometriosis is the probable consequence. Patients often experience overlapping symptoms such as dysmenorrhea, dyspareunia, and infertility.</div></div><div><h3>Material and methods</h3><div>This study analysed cases of sonographically detected uterine scar defects, subsequently undergoing laparoscopy at the University Clinic St. Hedwig, in Regensburg, between 2020 and 2024. Herefore, surgery reports were reviewed, focusing on extragenital endometriosis, symptoms of Cesarean Scar Disorder (CSD), niche morphology, uterine position, and endometriosis localisation using the #Enzian classification.</div></div><div><h3>Results</h3><div>Extragenital endometriosis was histologically confirmed in 45 of 94 patients (47.9 %) with symptomatic or large uterine niches. A significant association was found between endometriosis and heavy menstrual bleeding (HMB) (p &lt; 0.001) as well as retroflexio uteri (p = 0.036). Symptoms related to CSD did not differ in patients with or without Endometriosis. Endometriotic implants were primarily located in the peritoneum behind the uterus and sacrouterine ligaments, supporting the hypothesis of retrograde menstruation.</div></div><div><h3>Conclusion</h3><div>There is significant overlap between the symptoms of endometriosis and CSD. Almost half of the patients with a symptomatic niche were found to have endometriosis, whereby the location of endometriosis supports the hypothesis of retrograde menstruation. However, the patient´s history of complaints is not indicative of the diagnosis of endometriosis. Therefore, all patients with CSD should be offered a laparoscopy and endometriosis surgery. All patients with a previous caesarean section presenting with symptoms of endometriosis should be offered standardised and high-quality niche diagnosis and treatment.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"26 ","pages":"Article 100386"},"PeriodicalIF":1.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143746475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The landscape of ovarian cancer surgery in Italy: Data from PNE","authors":"Laura Grazia Zompì ,&nbsp;Cerbone Marco ,&nbsp;Pietro Quarto ,&nbsp;Christopher Clark ,&nbsp;Tommaso Difonzo ,&nbsp;Salvatore Lopez ,&nbsp;Vera Loizzi ,&nbsp;Cormio Gennaro","doi":"10.1016/j.eurox.2025.100383","DOIUrl":"10.1016/j.eurox.2025.100383","url":null,"abstract":"<div><h3>Objective</h3><div>Ovarian cancer (OC) in Italy is tenth in incidence among tumors in females, and it is the cause of 30 % of deaths due to gynecological tumors. The objective of this study is to evaluate the volume of patients undergoing surgical treatment for OC in Italian hospital facilities.</div></div><div><h3>Methods</h3><div>An analysis of hospitalization volumes due to OC in Italian medical facilities in 2022 based on the Piano Nazionale Esiti was performed. Centers were divided into 3 categories, according to the annual number of hospitalizations due to OC (above 30, between 20 and 29, below 20); the percentage of patients treated in each category of hospitals was calculated. Additionally, an evaluation of the active mobility (meaning the number of patients living outside the region but receiving treatment in the region taken into examination) and passive mobility (meaning the number of patients living inside the examined region but choosing to receive treatment in centers located outside of the region itself) was carried out for each region.</div></div><div><h3>Results</h3><div>The study showed that, in 11 Italian regions, most of OC cases are treated in medical centers with patient volumes of less than 20 cases per year. Only in 6 regions, OC cases are mostly treated in larger centers; in these same regions, the highest percentages of active mobility are recorded. Finally, in 6 Italian regions, passive mobility exceeds 50 % of regional cases.</div></div><div><h3>Conclusions</h3><div>Nowadays, the landscape of OC treatment in Italy is extremely heterogeneous. In most regions, patients receive treatment in low volume centers; concurrently, huge volumes of patients hailing from the entire national territory are treated in a limited number of centers.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"26 ","pages":"Article 100383"},"PeriodicalIF":1.5,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infertility-related stress and marital intimacy among infertile couples undergoing in vitro fertilization treatment in Western Iran: A cross-sectional study","authors":"Sara Abdoli ,&nbsp;Salman Khazaei ,&nbsp;Faezeh Fazli ,&nbsp;Shamim Pilehvari ,&nbsp;Ensiyeh jenabi","doi":"10.1016/j.eurox.2025.100384","DOIUrl":"10.1016/j.eurox.2025.100384","url":null,"abstract":"<div><h3>Background</h3><div>Given the fundamental role of fertility and childbearing in Iranian families, along with its cultural and social dimensions, and considering the importance of paying attention to marital issues among infertile couples, despite the limited and contradictory studies in this area, the present research aimed to Study marital intimacy and infertility stress in infertile couples undergoing in Vitro Fertilization (IVF) treatment in the west of Iran.</div></div><div><h3>Methods</h3><div>In 2023, a cross-sectional study from 1 September until December was undertaken on 117 couples at an Infertility Center in Hamadan City, Iran. Measurement tools were demographic characteristics, Newton's infertility stress questionnaire and the marital intimacy questionnaire. A convenience sampling method was utilized to recruit a total of 117 eligible women, each part of a couple, for the study. All participants completed the questionnaires of demographic characteristics, newton's infertility stress and the marital intimacy as required. Data analysis was carried out using Stata-17 software, with significance set at a level below 0.05.</div></div><div><h3>Results</h3><div>In the present study the number of 234 cases was investigated. There wasn't a significant difference observed in infertility-related stress domains by gender (P &gt; 0.05).Significant direct correlations were observed between infertility-related stress and age (r = 0.55, P &lt; 0.001), duration of marriage(r = 0.72, P &lt; 0.001), duration of infertility (r = 0.64, P &lt; 0.001), and duration of treatment (r = 0.67, P &lt; 0.001). Conversely, marital intimacy exhibited significant inverse correlations with these variables (P &lt; 0.001). Additionally, a significant negative correlation was found between marital intimacy and infertility-related stress (r = -0.67, P &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>The present study has shown that the mean score of marital intimacy among women is significantly higher than men. Additionally, there is a significant negative correlation between marital intimacy and infertility-related stress. Considering the importance of mental health in infertile couples and its potential impact on the outcome of IVF treatment, it appears that supportive interventions and counseling sessions to increase marital intimacy in infertile couples undergoing IVF treatment.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"26 ","pages":"Article 100384"},"PeriodicalIF":1.5,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers and enablers to postnatal care utilization in the Oshana region of Namibia: A qualitative study","authors":"Enos Moyo ,&nbsp;Perseverance Moyo ,&nbsp;Tafadzwa Dzinamarira ,&nbsp;Andrew Ross","doi":"10.1016/j.eurox.2025.100385","DOIUrl":"10.1016/j.eurox.2025.100385","url":null,"abstract":"<div><h3>Background</h3><div>Postnatal care (PNC) service utilization remains low in Namibia, including in the Oshana region, with only 20 % of newborn babies accessing them within two days of delivery in 2021, which is much lower than the 69 % of mothers nationwide who utilized PNC services. As low PNC utilization is linked to high maternal and child morbidity and mortality, this study aimed to explore the barriers and enablers of PNC utilization among women in the Oshana region of Namibia.</div></div><div><h3>Methods</h3><div>A descriptive qualitative design within an explanatory sequential mixed methods design was used<strong>.</strong> 13 female participants were recruited from the Oshana region's public healthcare facilities through purposive sampling with maximum variation. Semi-structured interviews were conducted, and the data was analyzed thematically.</div></div><div><h3>Results</h3><div>Six themes and 15 subthemes emerged from the barriers, while five themes and 11 subthemes emerged from the enabling factors. Themes related to barriers and enablers included personal, household, community, cultural, health system, and economic factors.</div></div><div><h3>Conclusion</h3><div>A comprehensive approach is needed to improve PNC utilization. This includes enhancing PNC knowledge, increasing healthcare accessibility, addressing gender norms and cultural beliefs, and improving the quality of PNC services.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"26 ","pages":"Article 100385"},"PeriodicalIF":1.5,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143724313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical investigation of fertility after uterine artery embolization combined with dilation and curettage(D&C) or D&C alone for cesarean scar pregnancies","authors":"Jie Gao ,&nbsp;Wenjing Wang ,&nbsp;Zhuoying Zhang,&nbsp;Saiming Cheng,&nbsp;Jiejun Cheng,&nbsp;Le Fu,&nbsp;Feng Gao","doi":"10.1016/j.eurox.2025.100379","DOIUrl":"10.1016/j.eurox.2025.100379","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this study was to compare the reproductive outcomes of patients with cesarean scar pregnancies (CSP) following uterine artery embolization (UAE) and dilation and curettage (D&amp;C) treatments, and to evaluate the impact of UAE on fertility.</div></div><div><h3>Materials</h3><div>and methods: A retrospective case-control study was conducted. Patients diagnosed with CSP between 2019 and 2021 were included in the study. Clinical data and fertility outcomes were collected and reviewed retrospectively. Patients were divided into two groups based on their treatment option: the UAE combined with D&amp;C group and the D&amp;C alone group.</div></div><div><h3>Results</h3><div>A total of 91 CSP patients were enrolled in the study. Of these, 49 were treated with D&amp;C, while 42 received UAE combined with D&amp;C. The average gestational age in the UAE group was significantly longer than that in the D&amp;C group. The average diameter of the gestational mass was significantly larger in the UAE group than in the D&amp;C group (42.2 ± 19.8 mm vs 23.8 ± 15.9 mm). The other clinical features were not significantly different between the two groups. The average menstrual recovery time was 1.0 ± 0.20 months (range: 1–2 months) in the D&amp;C group, and 2.0 ± 2.85 months (range: 1–18 months) in the UAE combined with D&amp;C group, with a significant difference between the two groups. The average menstrual blood volume (MBV) decreased in 79 % of patients in the UAE group, compared to 18 % in the D&amp;C group, with a significant difference between the two groups. There was no significant difference between the two groups in terms of pregnancy rate and birth rate (75 % vs 78 %, 63 % vs 56 %).</div></div><div><h3>Conclusion</h3><div>UAE combined with D&amp;C is an efficient and safe treatment for CSP. Our study showed that decreased MBV and longer menstrual recovery time in UAE combined with D&amp;C group, but there are no statistical difference in fertility outcomes between the two groups, which suggests probably a reversible impact on the reproductive function.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"26 ","pages":"Article 100379"},"PeriodicalIF":1.5,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143686980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Could blastocysts derived from abnormal fertilized zygotes be used? A systematic review and meta-analysis","authors":"Yiqing Wu ,&nbsp;Jinglei Xue ,&nbsp;Mixue Tu ,&nbsp;Yifeng Liu ,&nbsp;Dan Zhang","doi":"10.1016/j.eurox.2025.100381","DOIUrl":"10.1016/j.eurox.2025.100381","url":null,"abstract":"<div><h3>Objectives</h3><div>Current guidelines advise against using embryos derived from mono-pronuclei (1PN) or non-pronuclei (0PN) zygotes for clinical purposes. Nevertheless, recent studies have demonstrated that 1PN and 0PN zygotes can lead to healthy births. This study aimed to investigate the pregnancy outcomes of 1PN and 0PN blastocysts.</div></div><div><h3>Methods</h3><div>PubMed, EMBASE, Web of Science and Cochrane databases were searched up to 14 March 2024. Eligible studies enrolled participants transferring 0PN or 1PN blastocysts, with two pronuclei (2PN) blastocysts used as the control. Clinical pregnancy rate, miscarriage rate and live birth rate were the main outcomes. The results were presented as odds ratios (OR) with 95 % confidence intervals (CI) using random-effect models with the Mantel–Haenszel method. Additionally, a stratified analysis was conducted based on the type of fertilization. The Newcastle–Ottawa scale (NOS) was used to evaluate the quality of the included studies.</div></div><div><h3>Results</h3><div>In total, 270 articles were identified, with 16 ultimately included in the meta-analysis. In total, 57,835 cycles were analysed: 1071 cycles in the 1PN group, 2324 cycles in the 0PN group, and 54,440 cycles in the 2PN group. The results indicated that 1PN or 0PN blastocysts were associated with lower clinical pregnancy rates and live birth rates than 2PN blastocysts. Interestingly, there was no significant difference in live birth rate between 1PN blastocysts and 2PN blastocysts in patients undergoing intracytoplasmic sperm injection (ICSI), nor between 0PN blastocysts and 2PN blastocysts in patients undergoing in-vitro fertilization (IVF).</div></div><div><h3>Conclusion</h3><div>Careful consideration should be given to the utilization of 1PN and 0PN blastocysts, especially if an improved methodology of non-invasive assessment of fertilization is available. At the very least, 1PN blastocysts in patients undergoing ICSI and 0PN blastocysts in patients undergoing IVF represent viable fertility options for patients facing abnormal fertilization in clinical practice.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"26 ","pages":"Article 100381"},"PeriodicalIF":1.5,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143686979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between regular physical activity during pregnancy and perinatal outcomes: A population-based cohort study","authors":"Šejla Heljezović ,&nbsp;Miha Lučovnik ,&nbsp;Ivan Verdenik ,&nbsp;Darija Šćepanović","doi":"10.1016/j.eurox.2025.100380","DOIUrl":"10.1016/j.eurox.2025.100380","url":null,"abstract":"<div><h3>Introduction</h3><div>Regular physical activity during pregnancy is associated with several maternal and neonatal health benefits. However, most studies focus on specific forms of exercise in low-risk populations, limiting generalizability.</div></div><div><h3>Objective</h3><div>To investigate associations between regular physical activity during singleton pregnancy and perinatal outcomes using a national perinatal registry.</div></div><div><h3>Methods</h3><div>A population-based cohort study was conducted using data from the Slovenian National Perinatal Information System (2013–2022), which included 190,331 singleton pregnancies. Regular physical activity was defined as any form of physical activity at least twice weekly throughout pregnancy. The outcomes analyzed included preterm birth (&lt;37 and &lt;32 weeks), preeclampsia, gestational hypertension, gestational diabetes mellitus (GDM), pelvic girdle pain, small-for-gestational-age (SGA) and large-for-gestational-age (LGA) neonates, cesarean delivery, urinary incontinence postpartum, and Apgar scores &lt; 7 at 5 minutes. Multivariate logistic regression adjusted for parity, maternal age, BMI, prepregnancy hypertension and diabetes, and gestational weight gain.</div></div><div><h3>Results</h3><div>Regular physical activity during pregnancy was reported by 69 % of the women. It was significantly associated with reduced odds of preterm birth (&lt;37 weeks, aOR 0.658; &lt;32 weeks, aOR 0.393), preeclampsia (aOR 0.719), gestational hypertension (aOR 0.708), pelvic girdle pain (aOR 0.808), SGA (aOR 0.903), LGA (aOR 0.902) and low Apgar scores (aOR 0.638). Physically active women with GDM were less likely to require insulin (aOR 0.768). No significant associations were found with cesarean delivery or urinary incontinence.</div></div><div><h3>Conclusion</h3><div>Regular physical activity during pregnancy, regardless of specific type, was associated with improved perinatal outcomes without safety concerns. These findings highlight the potential benefits of encouraging physical activity during pregnancy in diverse populations.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"26 ","pages":"Article 100380"},"PeriodicalIF":1.5,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}