European Journal of Obstetrics and Gynecology and Reproductive Biology: X最新文献

筛选
英文 中文
Exploring the interplay between food security and antenatal care utilization among pregnant women in Southern Ethiopia: Insights from an institution-based cross-sectional study 探索埃塞俄比亚南部孕妇的粮食安全与产前护理利用率之间的相互作用:基于机构的横断面研究的启示
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-02-13 DOI: 10.1016/j.eurox.2024.100288
Gemeda Wakgari Kitil , Lema Fikadu Wedajo , Gizu Tola Feyisa , Bekem Dibaba Degefa , Shambel Negese Marami , Agmasie Damtew Walle , Alex Ayenew Chereka , Dagne Deresa Dinagde
{"title":"Exploring the interplay between food security and antenatal care utilization among pregnant women in Southern Ethiopia: Insights from an institution-based cross-sectional study","authors":"Gemeda Wakgari Kitil ,&nbsp;Lema Fikadu Wedajo ,&nbsp;Gizu Tola Feyisa ,&nbsp;Bekem Dibaba Degefa ,&nbsp;Shambel Negese Marami ,&nbsp;Agmasie Damtew Walle ,&nbsp;Alex Ayenew Chereka ,&nbsp;Dagne Deresa Dinagde","doi":"10.1016/j.eurox.2024.100288","DOIUrl":"10.1016/j.eurox.2024.100288","url":null,"abstract":"<div><h3>Background</h3><p>Ensuring the satisfaction of pregnant women with antenatal care is crucial for positive pregnancy outcomes and their engagement with emerging technologies and alternative care models. Maintaining high satisfaction during the antenatal period significantly impacts the well-being of both the expectant mother and the unborn child. Despite the recognized importance of antenatal care satisfaction, comprehensive information on satisfaction levels and influencing factors in the specific study area is lacking. Therefore, this study aims to assess antenatal care service satisfaction and associated factors among pregnant women in Arba Minch town, southern Ethiopia.</p></div><div><h3>Methods</h3><p>We conducted an institution-based cross-sectional study among 418 pregnant women from December 2022 to January 30, 2023, using a systematic sampling method. Data were collected using the Kobo Toolbox and analyzed with SPSS Version 26. The threshold for statistical significance was set at a p-value of less than 0.05.</p></div><div><h3>Results</h3><p>Out of 418 participants, 54.3% (95% CI=49.4–60.4) expressed satisfaction with antenatal care services. Factors significantly associated with women's satisfaction included: being unable to read and write (AOR=2.37; 95% CI: 1.97–3.80), being aged 25–29 years (AOR=3.20; 95% CI: 1.65–6.22), receiving antenatal care at a hospital (AOR=1.81; 95% CI: 1.05–3.12), having a previous history of antenatal visits (AOR=2.59; 95% CI: 1.26–5.30), a monthly income of 2500–5000 ETB (AOR=1.44; 95% CI: 1.21–3.94), waiting times of less than 30 min (AOR=2.59; 95% CI: 1.52–4.41), maintaining a positive attitude towards antenatal care (AOR=2.50; 95% CI: 1.05–3.65), and having a secure food source (AOR=2.06; 95% CI: 1.13–3.78).</p></div><div><h3>Conclusion</h3><p>Over 54% of participants were satisfied with antenatal care services. To improve satisfaction levels, recommended strategies include enhancing healthcare infrastructure, establishing maternity waiting areas, reducing waiting times, and expanding services to remote areas.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"21 ","pages":"Article 100288"},"PeriodicalIF":0.0,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161324000085/pdfft?md5=817e874c247436611cba2f08ff465124&pid=1-s2.0-S2590161324000085-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139833220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Female sexuality across the menopausal age group: A cross sectional study 更年期年龄组的女性性行为:一项横断面研究
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-02-11 DOI: 10.1016/j.eurox.2024.100287
Rajlaxmi Mundhra, Anupama Bahadur, Kavita Khoiwal, Mukesh Kumar, Shivani Singh Chhetri, Jaya Chaturvedi
{"title":"Female sexuality across the menopausal age group: A cross sectional study","authors":"Rajlaxmi Mundhra,&nbsp;Anupama Bahadur,&nbsp;Kavita Khoiwal,&nbsp;Mukesh Kumar,&nbsp;Shivani Singh Chhetri,&nbsp;Jaya Chaturvedi","doi":"10.1016/j.eurox.2024.100287","DOIUrl":"10.1016/j.eurox.2024.100287","url":null,"abstract":"<div><h3>Background</h3><p>Female sexual dysfunction (FSD) is an important health issue and its relationship with menopausal symptoms needs special attention.</p></div><div><h3>Objective</h3><p>To identify the frequency of FSD in middle aged women and assess its relationship with obesity and menopausal symptoms.</p></div><div><h3>Methods</h3><p>This was a cross sectional study performed at a tertiary care centre in North India over a period of one year from June 2022 to May 2023. Sexually active women aged 40–55 years were included in the study sample. Exclusion criteria included those not willing to participate, having pregnancy, malignancy, mental illness or history of pelvic surgery. Baseline demographic and anthropometric details were noted. Sexual function and menopausal symptoms were assessed using Menopause Rating Scale (MRS) and Female Sexual Function Index Scale (FSFI) questionnaire respectively.</p></div><div><h3>Results</h3><p>Among one hundred and forty three sexually active middle aged women, 43 women had FSD (30.06%). FSD was observed in 9.09%, 22.73% and 45.45% in- 40–45 years, 46–50 years and 51–55 years respectively. No significant difference was seen in desire (p value=0.281), arousal (p value=0.424), lubrication (p value=0.143), orgasm (p value=0.637), satisfaction (p value=0.675), pain (p value=0.833), total score (p value=0.601) between body mass index (kg/m²). A significant strong negative correlation of somatic, urogenital, psychological and total MRS scores with female sexuality domains was observed excepting non-significant mild negative correlation between somatic with pain and psychological with orgasm and pain.</p></div><div><h3>Conclusion</h3><p>Female sexual dysfunction are quite common and has negative correlation with menopausal symptoms. Health care providers need to focus on this issue as part of their routine assessment for better quality of life.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"21 ","pages":"Article 100287"},"PeriodicalIF":0.0,"publicationDate":"2024-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161324000073/pdfft?md5=8b479b10669be3d4484ad28dad062a33&pid=1-s2.0-S2590161324000073-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139877420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility of neurosonography in CHD-fetuses and controls in a clinical tertiary setting 在临床三级机构中对患有先天性心脏病的胎儿和对照组进行神经超声检查的可行性
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-02-10 DOI: 10.1016/j.eurox.2024.100289
Sheila M. Everwijn , Jiska F. van Bohemen , Fenna A. Jansen , Sylke J. Steggerda , Aalbertine K. Teunissen , Monique C. Haak
{"title":"Feasibility of neurosonography in CHD-fetuses and controls in a clinical tertiary setting","authors":"Sheila M. Everwijn ,&nbsp;Jiska F. van Bohemen ,&nbsp;Fenna A. Jansen ,&nbsp;Sylke J. Steggerda ,&nbsp;Aalbertine K. Teunissen ,&nbsp;Monique C. Haak","doi":"10.1016/j.eurox.2024.100289","DOIUrl":"https://doi.org/10.1016/j.eurox.2024.100289","url":null,"abstract":"<div><h3>Objective</h3><p>Ultrasonographic examination is the first-tier test to detect abnormal development of central nervous system (CNS). In optimal conditions, neurosonography can detect all important hallmarks of CNS development. It is, however, not known how the performance of this modality is in a routine setting. We aimed to evaluate the feasibility of neurosonography in a time-limited routine setting.</p></div><div><h3>Study design</h3><p>We have performed a prospective study in which we have included a group of pregnant women carrying a fetus with an isolated congenital heart defect (CHD), and a control group of fetuses without structural anomalies. We have performed basic neurosonography examination according to the guideline ‘how to perform a basic screening examination of the CNS’, published by the international society of ultrasound in obstetrics and gynecology in both groups. In all these examinations, 9 brain structures were scored in 3 different planes, by researchers that were blinded for group allocation. A sufficient neurosonogram was performed when 7 or more out of 9 CNS structures were clearly visible during the off-line scoring of the examination.</p></div><div><h3>Results</h3><p>A total of 574 neurosonographic examinations were performed in 151 fetuses, 90 in the CHD-group and 61 in the control group. A sufficient neurosonogram could be performed in 79% (234/294) of cases in a clinical setting (CHD cases) and in 90% (253/280) of control pregnancies. Higher maternal BMI (&gt;30), maternal age, fetal cephalic position, fetal gender and placental position did not significantly influence neurosonography scores.</p></div><div><h3>Conclusion</h3><p>In clinical setting, basic fetal neurosonography can be sufficiently performed in the majority of cases. This was not significantly influenced by maternal or fetal factors. The optimal gestational age for neurosonography is between 22 and 34 weeks.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"21 ","pages":"Article 100289"},"PeriodicalIF":0.0,"publicationDate":"2024-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161324000097/pdfft?md5=387429e04a46981d374b4707b26bae12&pid=1-s2.0-S2590161324000097-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139743206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Methotrexate as the first-line treatment of unruptured tubular ectopic pregnancies with high initial human chorionic gonadotropin levels: A retrospective cohort 将甲氨蝶呤作为初始人类绒毛膜促性腺激素水平较高的未破裂输卵管异位妊娠的一线治疗方法:回顾性队列
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-02-07 DOI: 10.1016/j.eurox.2024.100286
Fatemeh Keikha , Shireen Shams Ardekani , Mohammadamin Parsaei , Nikan Zargarzadeh , Alireza Hadizadeh , Azadeh Tarafdari
{"title":"Methotrexate as the first-line treatment of unruptured tubular ectopic pregnancies with high initial human chorionic gonadotropin levels: A retrospective cohort","authors":"Fatemeh Keikha ,&nbsp;Shireen Shams Ardekani ,&nbsp;Mohammadamin Parsaei ,&nbsp;Nikan Zargarzadeh ,&nbsp;Alireza Hadizadeh ,&nbsp;Azadeh Tarafdari","doi":"10.1016/j.eurox.2024.100286","DOIUrl":"https://doi.org/10.1016/j.eurox.2024.100286","url":null,"abstract":"<div><h3>Objectives</h3><p>To evaluate the effectiveness of the first-line medical management with Methotrexate (MTX) in the treatment of patients with stable tubal Ectopic Pregnancies (EPs) and varying ranges of Beta-Human Chorionic Gonadotropin (β-HCG) levels.</p></div><div><h3>Materials and methods</h3><p>In this retrospective cohort study, we reviewed the medical records of a total of 184 patients with the diagnosis of tubal EP, who received MTX as their first-line treatment. Patients with a baseline β-HCG&lt; 4800 mIU/mL received single-dose MTX (n = 136) and those with an initial β-HCG≥ 4800 mIU/mL underwent the double-dose MTX regimen (n = 48). The treatment success was determined by evaluating the reported weekly β-HCG levels of the patients.</p></div><div><h3>Results</h3><p>Baseline β-HCG and mass size in the single-dose group were 1895.1 ± 1463.4 mIU/mL and 2.2 ± 1.1 cm, respectively, compared to 17,867.6 ± 31,870.5 mIU/mL and 2.3 ± 1.1 cm in the double-dose group. Treatment duration was 30.6 ± 16.9 days for single dose and 41.0 ± 27.0 days for double dose, with additional MTX in 27.2% and 12.5% in respective groups. Single dose achieved a 92.6% success rate, and double dose, 81.3%, without serious adverse effects. No significant effects were seen for either baseline β-HCG and mass size on the treatment success rates of both groups (p-value&gt;0.05). However, the presence of Fetal Heart Rate (FHR) was associated with poorer responses only in the single-dose group (p-value=0.034).</p></div><div><h3>Conclusions</h3><p>Medical management with MTX shows promise as a first-line treatment for tubal EPs with β-HCG&gt; 2000, suggesting a potential reassessment of existing guidelines in light of this emerging evidence. However, further research seems crucial in this field.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"21 ","pages":"Article 100286"},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161324000061/pdfft?md5=431263de8c006c6db5bdefabced89d80&pid=1-s2.0-S2590161324000061-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139714938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tourniquet on the low segment of the uterus reduces blood loss in postpartum hemorrhage during hysterectomy for placenta accreta: Old but gold 在因胎盘早剥而进行子宫切除术时,子宫低段的止血带可减少产后出血的失血量:老而弥新。
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-02-02 DOI: 10.1016/j.eurox.2024.100285
Hassine S. Abouda , Sofiene B. Marzouk , Yecer Boussarsar , Haithem Aloui , Hatem Frikha , Rami Hammami , Badis Chennoufi , Hayen Maghrebi
{"title":"Tourniquet on the low segment of the uterus reduces blood loss in postpartum hemorrhage during hysterectomy for placenta accreta: Old but gold","authors":"Hassine S. Abouda ,&nbsp;Sofiene B. Marzouk ,&nbsp;Yecer Boussarsar ,&nbsp;Haithem Aloui ,&nbsp;Hatem Frikha ,&nbsp;Rami Hammami ,&nbsp;Badis Chennoufi ,&nbsp;Hayen Maghrebi","doi":"10.1016/j.eurox.2024.100285","DOIUrl":"10.1016/j.eurox.2024.100285","url":null,"abstract":"<div><h3>Objectives</h3><p>To investigate the feasibility, safety, and efficiency after application of a cervical tourniquet during caesarian hysterectomy owing to placenta accreta</p></div><div><h3>Study design</h3><p>It was a monocentric prospective observational study for 3 years. Patients were allocated into two group: Group Tourniquet: (TG) in which a cervical tourniquet was systematically applied during hysterectomy, control group (CG) when the caesarian hysterectomy was performed without.</p></div><div><h3>Results</h3><p>20 patients in the TG and 23 patients in the CG. Tourniquet application significantly reduced per operative estimated blood loss volume (TG: 530 ± 135 vs 940 ± 120 ml in the CG, p = 0.0074), ΔHB (0.6 [0.3–1.9] vs 2.5[2.5–3.6] g/dl in the CG, p = 0.006) RBC transfusion requirements’ (TG: 2 ± 1.7 vs 4.3 ± 2.1 units in the CG, p = 0.046) procedure duration (TG: 98 ± 21 vs 137 ± 33 min in the CG, p = 0.015), clotting disorders (TG: 1 (5%) vs 6 (26,1%) in the CG, p = 0.013) and the incidence of bladder wounds (TG: 1 (5%) vs 5 (21,7%) in the CG, p = 0.048). There was no significant difference regarding ICU transfer rate (TG: 16 (80%) vs 20 (86.9%) in the CG, p = 0.53) or length of stay (TG: 1.4 [2,3] vs 2.3 [1–4] days in the CG, p = 0.615) and digestive wound (TG: 0 vs 2 (8,7%) in the CG, p = 0.641).</p></div><div><h3>Conclusion</h3><p>In case of a radical management of placenta accreta. A strategy that involves the application of a cervical Tourniquet should be considered as a feasible, safe and above all efficient alternative to prevent blood spoliation.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"21 ","pages":"Article 100285"},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S259016132400005X/pdfft?md5=d4d2c0cf7c3fcbb6d205d8eb8981cf1f&pid=1-s2.0-S259016132400005X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139684359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors affecting sexual-self-esteem among Iranian women 影响伊朗妇女性自尊的因素
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-01-26 DOI: 10.1016/j.eurox.2024.100284
Sahar Safshekan, Zahra Bostani Khalesi
{"title":"Factors affecting sexual-self-esteem among Iranian women","authors":"Sahar Safshekan,&nbsp;Zahra Bostani Khalesi","doi":"10.1016/j.eurox.2024.100284","DOIUrl":"10.1016/j.eurox.2024.100284","url":null,"abstract":"<div><h3>Introduction</h3><p>The quality of marital relationships is positively impacted by women's sexual self-esteem. This study aims to determine the factors that affect sexual self-esteem among Iranian women.</p></div><div><h3>Methods</h3><p>A total of 1176 eligible women who have been referred to comprehensive healthcare centers of Rasht, participated in this analytical cross-sectional study. A stratified two-stage cluster sampling methodology was applied to achieve samples. Data were collected using a validated Persian version of the Sexual Self-Esteem Inventory in Women-Short Form and related factors checklist.</p></div><div><h3>Results</h3><p>The mean sexual self-esteem score of the respondents was 103.97(SD =5.29) in this study. Education level of the woman (B = 2.622, P &lt; 0.032), employment status of the woman (B= 9.24, P &lt; 0.01), duration of the marriage (B = 11.47, P &lt; 0.01), body image (B = 3.446, P &lt; 0.01), childhood sexual abuse experiences (B = −0.363, P &lt; 0.01), was related with sexual self-esteem. The sexual self-esteem score increased with an increase in higher levels of education, employment of women, an increase in the duration of the marriage, and a positive body image. However, there was an inverse relationship between the experience of childhood sexual abuse and sexual self-esteem.</p></div><div><h3>Conclusions</h3><p>The findings revealed that sexual self-esteem in women is influenced by background, intrapersonal, and interpersonal factors that should be approached in education, counseling, and therapy.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"21 ","pages":"Article 100284"},"PeriodicalIF":0.0,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161324000048/pdfft?md5=01a6ada1e23a7eec18970ef2a119a66a&pid=1-s2.0-S2590161324000048-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139637718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perinatal outcomes of emergency and elective cervical cerclages 急诊和择期宫颈环扎术的围产期结果。
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-01-26 DOI: 10.1016/j.eurox.2023.100276
Aytaj Jafarzade , Sveta Aghayeva , Tamer M. Mungan , Aydan Biri , Elchin Jabiyev , Osman Ufuk Ekiz
{"title":"Perinatal outcomes of emergency and elective cervical cerclages","authors":"Aytaj Jafarzade ,&nbsp;Sveta Aghayeva ,&nbsp;Tamer M. Mungan ,&nbsp;Aydan Biri ,&nbsp;Elchin Jabiyev ,&nbsp;Osman Ufuk Ekiz","doi":"10.1016/j.eurox.2023.100276","DOIUrl":"10.1016/j.eurox.2023.100276","url":null,"abstract":"<div><h3>Objective</h3><p>This study aims to compare the perinatal outcomes of emergency and elective cervical cerclages.</p></div><div><h3>Material and Methods</h3><p>This retrospective study included a total of 247 patients, with a total of 142 emergency (with a history of mid-trimester miscarriage or vaginal delivery of &lt; 34 weeks and cervical length &lt; 25 mm) and 105 electives cerclage patients (with painless cervical dilation and cervical length &lt;25 mm) who had cerclage with the vaginal cervical McDonald technique between 1.1.2017–1.10.2022. Pregnant women with normal screening tests at weeks 11–14, normal fetal morphology, and singleton pregnancies were included in the study. The study was conducted in a tertiary center providing NICU care for &lt; 1500 g, less than 32 weeks of age, and on a mechanical ventilator. Obstetric and perinatal outcomes were reviewed.</p></div><div><h3>Results</h3><p>There was no statistical difference between the two groups regarding maternal age or BMI. It was observed that the week of delivery was greater for elective cerclages than for emergency cerclages (mean 34.6 GW versus 30.8 GW). The week of cerclage application was statistically higher in emergency cerclage (19.2 GW versus 16.3 GW p &lt; 0.000). In addition, when we evaluated perinatal complications: prenatal Ex (n34 vs. n8 p &lt; 0.001), C-reactive protein which is a marker of neonatal infection (12.7 mg/L vs. 2.5 mg/L p &lt; 0.022), antibiotic use in the NICU (n 35 vs. n23 p &lt; 0.050), the number of days of antibiotic use in the NICU (mean 15.3 days vs. 10.4 days p &lt; 0.024), rate of NICU intubation (n 27 vs. n 11 p &lt; 0.003), and neonatal sequelae (n 16 vs. n 6 p &lt; 0.016) were significantly higher in the emergency cerclage group than in the elective cerclage group. There was no found significant difference between the progesterone given and not given progesterone after the procedure in term of the weeks of delivery (<em>p &lt;</em> 0.810 emergency cervical cerclage; p &lt; 0681 elective cervical cerclage)</p></div><div><h3>Conclusion</h3><p>Considering the available information, the results of elective cerclage seem to be more beneficial for the patient than those of emergency cerclage. Therefore, it would be more reasonable to perform elective cerclage in patients with mid-trimester or preterm miscarriage and concomitant cervical shortening before emergency cerclage is required. Furthermore, the benefit of progestin, in addition after surgical intervention, has not been established.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"21 ","pages":"Article 100276"},"PeriodicalIF":0.0,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161323001023/pdfft?md5=3474c0a79d1b1646781303bc344b55af&pid=1-s2.0-S2590161323001023-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139635299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review of the pharmacology, clinical outcomes, and real-world effectiveness, safety, and non-contraceptive effects of NOMAC/E2 对 NOMAC/E2 的药理学、临床结果、实际效果、安全性和非避孕效果的综述
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-01-22 DOI: 10.1016/j.eurox.2024.100283
Franca Fruzzetti , Rogerio Bonassi Machado , Iñaki Lete , Amisha Patel , Mitra Boolell
{"title":"A review of the pharmacology, clinical outcomes, and real-world effectiveness, safety, and non-contraceptive effects of NOMAC/E2","authors":"Franca Fruzzetti ,&nbsp;Rogerio Bonassi Machado ,&nbsp;Iñaki Lete ,&nbsp;Amisha Patel ,&nbsp;Mitra Boolell","doi":"10.1016/j.eurox.2024.100283","DOIUrl":"10.1016/j.eurox.2024.100283","url":null,"abstract":"<div><p>Selecting an appropriate oral contraceptive can be challenging for healthcare professionals due to the abundance of marketed contraceptive options with different clinical and real-world effectiveness and safety profiles. Nomegestrol acetate + 17β-estradiol (NOMAC/E2) is a combined oral contraceptive (COC) that inhibits ovulation by suppressing ovarian function by a 17-hydroxy-progesterone derivative and an estrogen identical to that endogenously produced by the ovaries. This narrative review examines clinical and real-world studies of NOMAC/E2 based on a background literature search using PubMed and Google Scholar. The review outlines the pharmacology of NOMAC/E2, including its progestational activity, pharmacokinetics, and effects on carbohydrate metabolism, lipid metabolism, and coagulation parameters, and summarizes key clinical efficacy and safety data that led to the approval of NOMAC/E2 in Europe, Brazil, and Australia. To help elucidate how NOMAC/E2 clinical trial data translate into a real-world setting, this review describes the effectiveness and safety of NOMAC/E2 in prospective studies that include over 90,000 users (half of whom received NOMAC/E2), outlining its effects on risk of thrombosis, menstrual bleeding patterns, weight, mood, acne, bone health, and patient quality of life. Non-contraceptive benefits of NOMAC/E2 for women with endometriosis, dysmenorrhea, or pre-menstrual dysphoric disorder are also discussed. These data demonstrate that NOMAC/E2 has a long half-life and rapid absorption, is effective at preventing unwanted pregnancies, and exhibits a favorable safety profile in both clinical trials and real-world settings. Importantly, NOMAC/E2 is not associated with increased risk of venous thromboembolism, a major safety concern of healthcare professionals for women receiving hormonal contraceptives. This review highlights NOMAC/E2 as a differentiated option among COCs and could help inform oral contraceptive choice to ultimately improve patient management and outcomes in real-world settings.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"21 ","pages":"Article 100283"},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161324000036/pdfft?md5=b7bd483d8606ff4d7054c7fc8312a4b5&pid=1-s2.0-S2590161324000036-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139637788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimizing blood conservation in caesarean sections: Intravaginal tamponade technique for abnormal placentae insertion "优化剖腹产手术的血液保存:异常胎盘植入阴道内填塞技术"
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-01-13 DOI: 10.1016/j.eurox.2024.100282
Laureline Moser, Manon Vouga, Khadidja Benkortbi, Emilie Boussac, Alexia Cuenoud, Joanna Sichitiu, David Desseauve
{"title":"Optimizing blood conservation in caesarean sections: Intravaginal tamponade technique for abnormal placentae insertion","authors":"Laureline Moser,&nbsp;Manon Vouga,&nbsp;Khadidja Benkortbi,&nbsp;Emilie Boussac,&nbsp;Alexia Cuenoud,&nbsp;Joanna Sichitiu,&nbsp;David Desseauve","doi":"10.1016/j.eurox.2024.100282","DOIUrl":"10.1016/j.eurox.2024.100282","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"21 ","pages":"Article 100282"},"PeriodicalIF":0.0,"publicationDate":"2024-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161324000024/pdfft?md5=7251c2cb8071edc0d02ef32daf86e79b&pid=1-s2.0-S2590161324000024-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139540559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fear of childbirth prolongs interpregnancy interval: A nationwide register-based quantile logistic regression analysis 对分娩的恐惧会延长孕间隔:基于全国登记的量子逻辑回归分析
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-01-12 DOI: 10.1016/j.eurox.2024.100281
Matias Vaajala , Ville M. Mattila , Ilari Kuitunen
{"title":"Fear of childbirth prolongs interpregnancy interval: A nationwide register-based quantile logistic regression analysis","authors":"Matias Vaajala ,&nbsp;Ville M. Mattila ,&nbsp;Ilari Kuitunen","doi":"10.1016/j.eurox.2024.100281","DOIUrl":"https://doi.org/10.1016/j.eurox.2024.100281","url":null,"abstract":"<div><h3>Introduction</h3><p>It is not well studied how fear of childbirth (FOC) influences the interpregnancy interval (IPI). Thus, we aimed to analyze the association between FOC and the length of the IPI.</p></div><div><h3>Methods</h3><p>All women having their first and second pregnancies during the study period (2004–2018) were gathered from the Finnish Medical Birth Register. A logistic regression model was used to assess the association between the FOC and subsequent length of the IPI. The length of the IPI was assessed separately for women with FOC in the first pregnancy, and for women who developed the FOC in the second pregnancy. IPIs with a length in the lower quartal were considered short IPIs, and length in the upper quartal as long IPIs. Adjusted odds ratios (aOR) with 95% CIs were compared between the groups.</p></div><div><h3>Results</h3><p>A total of 52 709 women with short IPI (&lt;1.05 years), 105 604 women with normal IPI, and 52 889 women with long IPI (&gt;2.57 years) were included. A total of 3606 women had FOC in the first pregnancy, and a total of 11 473 had their first FOC diagnosis in the second pregnancy. Women with FOC in the first pregnancy had lower odds for short IPI (aOR 0.88, CI 0.81–0.95) and higher odds for long IPI (aOR 1.30, CI 1.21–1.40). Women with the first FOC diagnosis in the second pregnancy had higher odds for long IPI (aOR 1.68, CI 1.61–1.75), When only vaginal deliveries in the first pregnancy were included, women with FOC in the second pregnancy had lower odds for long IPI (aOR 0.71, CI 0.66–0.75) and higher odds for long IPI (aOR 1.52, CI 1.41–1.62), when only cesarean section was included.</p></div><div><h3>Conclusion</h3><p>The main finding of this study was that women with FOC had notably higher odds for long IPI. The etiologic and background factors behind FOC should be better recognized and prevented, and FOC should not only be considered as a complicating factor for pregnancy and delivery but also a factor that strongly affects the desire of women to get pregnant again.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"21 ","pages":"Article 100281"},"PeriodicalIF":0.0,"publicationDate":"2024-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161324000012/pdfft?md5=d8eed998323b97f8aa348d8e781f3c8b&pid=1-s2.0-S2590161324000012-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139480088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信