European Journal of Obstetrics and Gynecology and Reproductive Biology: X最新文献

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Epidemiology and placental pathology of intrauterine fetal demise in a tertiary hospital in the Philippines 菲律宾一家三级医院胎儿宫内死亡的流行病学和胎盘病理学
IF 1.5
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-09-01 DOI: 10.1016/j.eurox.2024.100338
Ourlad Alzeus G. Tantengco , Michele H. Diwa , Patrick Michael M. Millagrosa , Clarissa L. Velayo
{"title":"Epidemiology and placental pathology of intrauterine fetal demise in a tertiary hospital in the Philippines","authors":"Ourlad Alzeus G. Tantengco ,&nbsp;Michele H. Diwa ,&nbsp;Patrick Michael M. Millagrosa ,&nbsp;Clarissa L. Velayo","doi":"10.1016/j.eurox.2024.100338","DOIUrl":"10.1016/j.eurox.2024.100338","url":null,"abstract":"<div><h3>Objectives</h3><p>The Philippines has at least 25,000 stillbirth or intrauterine fetal demise (IUFD) cases every year. Despite its burden, there is scarce information on IUFD epidemiology in the Philippines. Hence, this study reported the epidemiology and placental pathology of IUFD in a tertiary hospital in the Philippines.</p></div><div><h3>Study design</h3><p>This cross-sectional study analyzed second- and third-trimester IUFD cases at the Philippine General Hospital from 2012 to 2021. We reviewed maternal sociodemographic and clinical characteristics and evaluated placental pathology. All statistical tests were done with GraphPad Prism software version 8.0.</p></div><div><h3>Results</h3><p>We recorded 947 (2.28 %) cases of IUFD out of 41,562 obstetric deliveries from 2012 to 2021. Out of 947 IUFD cases, 532 had placental pathology reports. Second-trimester IUFD cases showed higher rates of no antenatal care (42.86 %) compared to third-trimester cases (10.61 %). Hypertensive disorders were more common in third-trimester IUFD. Infarcts (23.34 %), calcifications (4.12 %), and hemorrhages/hematomas (3.00 %) were the most prevalent placental abnormalities. While these abnormalities were more common in third-trimester IUFD, placental and fetal membrane infections like chorioamnionitis were more frequent in second-trimester IUFD.</p></div><div><h3>Conclusion</h3><p>The results highlighted the differences in maternal sociodemographic and clinical characteristics, and placental pathology between second- and third-trimester cases of IUFD. These observations revealed distinct pathological processes and potential etiologies contributing to IUFD in the Philippines.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161324000589/pdfft?md5=e06329b33a3273bb95a77948f3f134ce&pid=1-s2.0-S2590161324000589-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142128483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perinatal outcomes in indian women with Antiphospholipid Antibody Syndrome (APS): Five year experience from a tertiary care centre 患有抗磷脂抗体综合征(APS)的印度妇女的围产期结局:一家三级医疗中心的五年经验
IF 1.5
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-08-30 DOI: 10.1016/j.eurox.2024.100340
Minakshi Rohilla, Mahak Bhardwaj, Vanita Jain
{"title":"Perinatal outcomes in indian women with Antiphospholipid Antibody Syndrome (APS): Five year experience from a tertiary care centre","authors":"Minakshi Rohilla,&nbsp;Mahak Bhardwaj,&nbsp;Vanita Jain","doi":"10.1016/j.eurox.2024.100340","DOIUrl":"10.1016/j.eurox.2024.100340","url":null,"abstract":"<div><h3>Background</h3><p>Antiphospholipid Syndrome (APS) is a systemic autoimmune thrombophilic condition characterized by obstetric manifestations, including pregnancy loss, preeclampsia and fetal growth restriction. Early diagnosis and management are key to improve maternal and neonatal outcomes.</p></div><div><h3>Objective</h3><p>The aim of this study is to assess the perinatal outcomes in APS, the development of various adverse pregnancy outcomes (APO), and their association with specific antibody profiles.</p></div><div><h3>Material methods</h3><p>This observational study was carried out on booked cases of singleton pregnancy and diagnosed cases of primary APS in our High-Risk Pregnancy (HRP) clinic from January 2018 to December 2022 after approval from institutional ethics committee. Forty-three confirmed cases of primary APS were enrolled and started on low-dose aspirin and low-molecular-weight heparin (LMWH) as per the patient's body weight after confirmation of fetal heart activity radiologically until 36 weeks of gestation as a standard of care.</p></div><div><h3>Results</h3><p>Forty patients (93 %) had obstetric APS, and three patients (7 %) had thrombotic APS. During the course of the current pregnancy, adverse pregnancy outcomes (APO) developed in 12 (30 %) out of 40 cases of obstetric APS and in all 3 patients with thrombotic APS. Preeclampsia was seen in 11 (25.5 %), FGR in 12 (27.9 %), and preterm birth in 7 (16.2 %) cases. Patients with an antibody profile showing the presence of Anti-β2 GP-I positivity and ACL positivity had fewer APOs (20 % and 29 %) in comparison to patients with a LA and triple positive antibody profile (55 % and 50 %).</p></div><div><h3>Conclusion</h3><p>Treatment of pregnant women with APS causes significant improvement in the live birth rate. The late pregnancy complications like preeclampsia, FGR, and premature birth, occurring despite treatment still remains a challenge and emphasizes the need for stringent antepartum surveillance and timely delivery.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161324000607/pdfft?md5=85d7e3293ae8c9dc7dc60408a7453e24&pid=1-s2.0-S2590161324000607-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142148082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postmortem fertilization: New Italian government guidelines affirm the legitimacy of this procedure. 死后受精:意大利政府的新指导方针确认了这一程序的合法性。
IF 1.5
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-08-22 DOI: 10.1016/j.eurox.2024.100337
Emanuela Turillazzi , Donato Morena , Matteo Scopetti , Vittorio Fineschi
{"title":"Postmortem fertilization: New Italian government guidelines affirm the legitimacy of this procedure.","authors":"Emanuela Turillazzi ,&nbsp;Donato Morena ,&nbsp;Matteo Scopetti ,&nbsp;Vittorio Fineschi","doi":"10.1016/j.eurox.2024.100337","DOIUrl":"10.1016/j.eurox.2024.100337","url":null,"abstract":"<div><p>Although posthumous reproduction (PHR) is viewed unfavorably by some, it may be a desirable option for subjects whose partners died before they could complete their family planning. With particular regard to posthumous embryo implantation, questions arise regarding the definition of \"conception\" when a couple undergoes in vitro fertilization while both are alive, but the embryo is implanted in a woman's womb after one parent has died. In accordance with Italian Law 40/2004, access to medically assisted reproduction is contingent upon the survival of both partners in a couple. The legislative prohibition remains in effect unless the application of the reproductive technique has already resulted in the formation of embryos, and implantation is permitted to uphold \"the rights of all the subjects involved, including the conceived\", as stated in Article 1 of Law 40/2004. Since the enactment of the legislation, a number of Italian courts have issued rulings on PHR on a case-by-case basis. Recent government guidelines in Italy have sought to balance these considerations, giving due weight to the will of the woman, the potential unborn child, and the previous consent of the donor partner.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161324000577/pdfft?md5=a565b9326437b812692366d1e84972ea&pid=1-s2.0-S2590161324000577-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142050252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Caesarean section and respiratory system disorders in newborns 剖腹产与新生儿呼吸系统疾病
IF 1.5
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-08-10 DOI: 10.1016/j.eurox.2024.100336
Maryam Yeganegi , Reza Bahrami , Sepideh Azizi , Zahra Marzbanrad , Nazanin Hajizadeh , Seyed Reza Mirjalili , Maryam Saeida-Ardekani , Mohamad Hosein Lookzadeh , Kamran Alijanpour , Maryam Aghasipour , Mohammad Golshan-Tafti , Mahmood Noorishadkam , Hossein Neamatzadeh
{"title":"Caesarean section and respiratory system disorders in newborns","authors":"Maryam Yeganegi ,&nbsp;Reza Bahrami ,&nbsp;Sepideh Azizi ,&nbsp;Zahra Marzbanrad ,&nbsp;Nazanin Hajizadeh ,&nbsp;Seyed Reza Mirjalili ,&nbsp;Maryam Saeida-Ardekani ,&nbsp;Mohamad Hosein Lookzadeh ,&nbsp;Kamran Alijanpour ,&nbsp;Maryam Aghasipour ,&nbsp;Mohammad Golshan-Tafti ,&nbsp;Mahmood Noorishadkam ,&nbsp;Hossein Neamatzadeh","doi":"10.1016/j.eurox.2024.100336","DOIUrl":"10.1016/j.eurox.2024.100336","url":null,"abstract":"<div><p>Cesarean section (C-section) delivery is associated with a higher risk of respiratory problems in newborns, particularly if performed electively at 37 weeks. This risk is greater than with spontaneous or induced labor but diminishes as gestation advances. To lower the incidence of respiratory issues in newborns, it is vital to promote natural labor, avoid unnecessary C-sections, and offer thorough prenatal care. Healthcare providers and expectant mothers should assess the risks and benefits of elective C-sections carefully. By advocating for natural labor and reducing unnecessary C-sections, the occurrence of respiratory problems in newborns can be decreased. Adequate prenatal care and monitoring are crucial for identifying and managing potential risk factors for respiratory diseases in newborns. It is crucial for healthcare professionals to educate expectant mothers about the risks of elective C-sections and the advantages of allowing labor to progress naturally. By fostering transparent communication and collaborative decision-making between healthcare providers and pregnant women, well-informed choices can be made that prioritize the health of both the mother and the baby. Furthermore, ongoing research and advancements in medical technology can improve our understanding of how delivery methods affect newborn respiratory health, ultimately leading to better outcomes and care practices in the future.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161324000565/pdfft?md5=4a2d8095be80f7ac0c848218b153ef48&pid=1-s2.0-S2590161324000565-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142012264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The interaction of breastfeeding and genetic factors on childhood obesity 母乳喂养与遗传因素对儿童肥胖的相互作用
IF 1.5
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-08-09 DOI: 10.1016/j.eurox.2024.100334
Mahsa Danaie , Maryam Yeganegi , Seyed Alireza Dastgheib , Reza Bahrami , Fatemeh Jayervand , Amirhossein Rahmani , Maryam Aghasipour , Mohammad Golshan-Tafti , Sepideh Azizi , Zahra Marzbanrad , Ali Masoudi , Amirmasoud Shiri , Mohamad Hosein Lookzadeh , Mahmood Noorishadkam , Hossein Neamatzadeh
{"title":"The interaction of breastfeeding and genetic factors on childhood obesity","authors":"Mahsa Danaie ,&nbsp;Maryam Yeganegi ,&nbsp;Seyed Alireza Dastgheib ,&nbsp;Reza Bahrami ,&nbsp;Fatemeh Jayervand ,&nbsp;Amirhossein Rahmani ,&nbsp;Maryam Aghasipour ,&nbsp;Mohammad Golshan-Tafti ,&nbsp;Sepideh Azizi ,&nbsp;Zahra Marzbanrad ,&nbsp;Ali Masoudi ,&nbsp;Amirmasoud Shiri ,&nbsp;Mohamad Hosein Lookzadeh ,&nbsp;Mahmood Noorishadkam ,&nbsp;Hossein Neamatzadeh","doi":"10.1016/j.eurox.2024.100334","DOIUrl":"10.1016/j.eurox.2024.100334","url":null,"abstract":"<div><p>Childhood obesity represents a pressing global public health concern due to its widespread prevalence and its close connection to early-life exposure to risk factors. The onset of obesity is contingent upon the interplay of genetic composition, lifestyle choices, and environmental as well as nutritional elements encountered during both fetal development and early childhood. This paper critically examines research discoveries in this area and concisely outlines the influence of breastfeeding on genetic predispositions associated with childhood obesity. Studies have demonstrated that breastfeeding has the potential to reduce childhood obesity by impacting anthropometric indicators. Moreover, the duration of breastfeeding is directly correlated with the degree to which it alters the risk of childhood obesity. Current explorations into the link between genetic factors transmitted through breast milk and childhood obesity predominantly focus on genes like FTO, Leptin, RXRα, PPAR-γ, and others. Numerous research endeavors have suggested that an extended period of exclusive breastfeeding is tied to a diminished likelihood of childhood obesity, particularly if sustained during the initial six months. The duration of breastfeeding also correlates with gene methylation, which could serve as the epigenetic mechanism underpinning breastfeeding's preventative influence against obesity. In summary, the thorough evaluation presented in this review underscores the intricate nature of the association between breastfeeding, genetic factors, and childhood obesity, providing valuable insights for future research efforts and policy formulation.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161324000541/pdfft?md5=fc5604297b57e1fd0f42fda90afdae01&pid=1-s2.0-S2590161324000541-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141984782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Motherhood on a precarious path: Pregnancy following breast carcinoma – Case report 岌岌可危的母亲之路:乳腺癌术后妊娠--病例报告
IF 1.5
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-08-08 DOI: 10.1016/j.eurox.2024.100335
Perković Pavo , Culej Bošnjak Diana , Bertović Žunec Ivan , Lučić Dejana , Duić Željko , Bursać Danijel
{"title":"Motherhood on a precarious path: Pregnancy following breast carcinoma – Case report","authors":"Perković Pavo ,&nbsp;Culej Bošnjak Diana ,&nbsp;Bertović Žunec Ivan ,&nbsp;Lučić Dejana ,&nbsp;Duić Željko ,&nbsp;Bursać Danijel","doi":"10.1016/j.eurox.2024.100335","DOIUrl":"10.1016/j.eurox.2024.100335","url":null,"abstract":"<div><p>Women of childbearing age frequently express a desire for pregnancy even after a diagnosis of breast cancer and after undergoing treatment. The average age of primiparous women is rising and gynecologists and oncologists are faced with inquiries about pursuing childbearing after the diagnosis of breast cancer. We present a case of a 39 year old women who came to our clinic in 39th week of gestation, gave vaginal birth to a vigorous neonatus and underwent into dyspnea just two hours after the delivery. She voluntarily disclosed her advanced stage of breast cancer diagnosis, as she feared it could lead to the termination of her pregnancy. After she was released from the hospital, she did not attend any follow-up appointments at our clinic, hence we have no knowledge whether she contacted her oncologist or the outcome of her primary disease.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161324000553/pdfft?md5=e7bef92dac97b519b9dbb0b6a7126a5b&pid=1-s2.0-S2590161324000553-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141978252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A letter to editor – Critical appraisal on “Determining the cost-effectiveness of follitropin alfa biosimilar compared to follitropin alfa originator in women undergoing fertility treatment in France.” 致编辑的信--关于 "确定在法国接受生育治疗的妇女中,与促性腺激素α原研药相比,促性腺激素α生物仿制药的成本效益 "的批判性评价。
IF 1.5
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-08-02 DOI: 10.1016/j.eurox.2024.100332
Juan-Enrique Schwarze, Vivek Chaudhari, Susana Montenegro, Claire Castello-Bridoux, Cristina Masseria, Claudia Roeder
{"title":"A letter to editor – Critical appraisal on “Determining the cost-effectiveness of follitropin alfa biosimilar compared to follitropin alfa originator in women undergoing fertility treatment in France.”","authors":"Juan-Enrique Schwarze,&nbsp;Vivek Chaudhari,&nbsp;Susana Montenegro,&nbsp;Claire Castello-Bridoux,&nbsp;Cristina Masseria,&nbsp;Claudia Roeder","doi":"10.1016/j.eurox.2024.100332","DOIUrl":"10.1016/j.eurox.2024.100332","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161324000528/pdfft?md5=c407e7e87d3c67784cca53efd5afe1c7&pid=1-s2.0-S2590161324000528-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141952533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply to Letter to Editor from Juan-Enrique Schwarze and colleagues – Critical appraisal on “Determining the cost-effectiveness of follitropin alfa biosimilar compared to follitropin alfa originator in women undergoing fertility treatment in France” 对 Juan-Enrique Schwarze 及其同事致编辑的信的回复--关于 "确定在法国接受生育治疗的妇女中,与促性腺激素 alfa 原研药相比,促性腺激素 alfa 生物仿制药的成本效益 "的批判性评价
IF 1.5
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-08-02 DOI: 10.1016/j.eurox.2024.100331
Matthieu Lehmann, Jean-Luc Pouly, Paul Barrière, Lauren Amy Boland, Samuel George Bean, Julian Jenkins
{"title":"Reply to Letter to Editor from Juan-Enrique Schwarze and colleagues – Critical appraisal on “Determining the cost-effectiveness of follitropin alfa biosimilar compared to follitropin alfa originator in women undergoing fertility treatment in France”","authors":"Matthieu Lehmann,&nbsp;Jean-Luc Pouly,&nbsp;Paul Barrière,&nbsp;Lauren Amy Boland,&nbsp;Samuel George Bean,&nbsp;Julian Jenkins","doi":"10.1016/j.eurox.2024.100331","DOIUrl":"10.1016/j.eurox.2024.100331","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161324000516/pdfft?md5=2b65bc3d6a296da8b629d076c992742b&pid=1-s2.0-S2590161324000516-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141962936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An eight-year analysis of robotic surgery in morbidly obese women with endometrial cancer in a tertiary center in Singapore 新加坡一家三级医疗中心对患子宫内膜癌的病态肥胖妇女进行机器人手术的八年分析
IF 1.5
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-08-02 DOI: 10.1016/j.eurox.2024.100330
Sabrina Lasini Gruhl, Muhammad Ashraf Yusoff, Hui Men Selina Chin, Ravichandran Nadarajah
{"title":"An eight-year analysis of robotic surgery in morbidly obese women with endometrial cancer in a tertiary center in Singapore","authors":"Sabrina Lasini Gruhl,&nbsp;Muhammad Ashraf Yusoff,&nbsp;Hui Men Selina Chin,&nbsp;Ravichandran Nadarajah","doi":"10.1016/j.eurox.2024.100330","DOIUrl":"10.1016/j.eurox.2024.100330","url":null,"abstract":"<div><h3>Introduction</h3><p>Surgical management of endometrial cancer is a total hysterectomy, bilateral salphingo-oophorectomy and pelvic lymph node dissection (THBSO-PLND), which is a challenging surgery in the morbidly obese. Data on morbidly obese women undergoing robotic surgery is limited in Asia. We share our experience in Singapore and aim to demonstrate that robotic surgery is safe and effective in morbidly obese women with endometrial cancer.</p></div><div><h3>Materials and Methods</h3><p>We performed a retrospective analysis of patients with BMI &gt; 40 kg/m2, who underwent robotic surgery from January 2016 to September 2023 at the Singapore General Hospital. We recruited a total of 33 patients who underwent robotic surgery for endometrial malignancy and analysed surgical outcomes, operative complications, and survival rates.</p></div><div><h3>Results</h3><p>The average age of patients was 53 years and mean BMI 45.7. The average operative time was 232 min and average blood loss 184 ml. 3 patients had THBSO while 27 underwent THBSO-PLND. None required conversion to laparotomy. 4 patients required a mini-laparotomy for the retrieval of bulky uterus. 12 required adhesiolysis. 6 patients had additional omentectomy done. The average inpatient stay was 4.8 days. The 1-year mortality rate is 0. However, 1 patient passed away 13 months after surgery due to complications from bowel obstruction and another passed away 39 months later due to disease recurrence. 1 patient readmitted on POD6 due to post-op ileus and another for port-site hematoma. Both were managed conservatively.</p></div><div><h3>Conclusion</h3><p>Robotic surgery is a safe and effective alternative surgical tool for women who are morbidly obese with endometrial cancer.</p></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590161324000504/pdfft?md5=533f4891b235450f57d371260dc3bcd9&pid=1-s2.0-S2590161324000504-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141962432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Did we observe changes in obstetric interventions in SARS-CoV-2 infected pregnant women at the beginning of COVID-pandemic in Belgium? Results of a nationwide population-based study. 在比利时 COVID 大流行之初,我们观察到 SARS-CoV-2 感染孕妇的产科干预措施发生了变化吗?一项基于全国人口的研究结果。
IF 1.5
European Journal of Obstetrics and Gynecology and Reproductive Biology: X Pub Date : 2024-07-25 DOI: 10.1016/j.eurox.2024.100328
An Vercoutere , Judith Racapé , Mbiton Joel Zina , Sophie Alexander , Karolien Benoit , Michel Boulvain , Régine Goemaes , Charlotte Leroy , Virginie Van Leeuw , Elena Costa , Sara Derisbourg , Jean-Christophe Goffard , Kristien Roelens , Griet Vandenberghe , Caroline Daelemans , on behalf of the B.OSS collaborative group
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