European Journal of Obstetrics and Gynecology and Reproductive Biology: X最新文献

{"title":"The effect of curcumin capsule on the severity and duration of primary dysmenorrhea among students: A triple-blind randomized controlled trial in the West of Iran","authors":"Sara Abdoli ,&nbsp;Salman Khazaei ,&nbsp;Maryam Mehrpooya ,&nbsp;Farideh kazemi ,&nbsp;Ensiyeh jenabi ,&nbsp;Reyhane Yazdaniroshan","doi":"10.1016/j.eurox.2025.100427","DOIUrl":"10.1016/j.eurox.2025.100427","url":null,"abstract":"<div><h3>Background</h3><div>The present study was conducted to evaluate the efficacy of curcumin capsules on the severity and duration of primary dysmenorrhea.</div></div><div><h3>Methods</h3><div>A randomized controlled trial conducted among female students at Hamadan University of Medical Sciences who met predetermined inclusion criteria in 2024 at 34 participants per group. In the intervention group, participants received curcumin capsules containing 500 mg of curcumin. These capsules were ingested once daily over the course of two menstrual cycles. The control group was administered placebo capsules, which contained 500 mg of starch, with the method of administration mirroring that of the intervention group. Data collection tools were including demographic characteristics questionnaire, visual pain ruler, pain duration and multidimensional verbal scale.</div></div><div><h3>Results</h3><div>after the intervention, a significant difference emerged (P &lt; 0.001). In the intervention group, dysmenorrhea severity decreased significantly from a mean of 6.5–4.53 in the first menstrual cycle and further reduced to 3.44 in the second cycle. In contrast, the control group showed no significant change. The intervention group's improvement was consistent across both cycles, highlighting the effectiveness of the intervention in reducing dysmenorrhea severity (P &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>curcumin capsules can be used as an effective and low-risk complementary treatment for reducing the severity and duration of primary dysmenorrhea.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"28 ","pages":"Article 100427"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145047864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of postoperative outcomes following hysterectomy versus sacrocolpopexy: Insights from global federated health research network","authors":"Muhammed A.M. Hammad,&nbsp;MacKinnly T. Knoerzer,&nbsp;Gamal M. Ghoniem","doi":"10.1016/j.eurox.2025.100433","DOIUrl":"10.1016/j.eurox.2025.100433","url":null,"abstract":"<div><h3>Objective</h3><div>To compare the risk of opioid use, antimicrobial utilization, and postoperative complications, including paralytic ileus, between patients undergoing abdominal hysterectomy and sacrocolpopexy.</div></div><div><h3>Methods</h3><div>Using a global federated health research network, we performed a retrospective cohort analysis. After 1:1 propensity score matching for age, BMI, race, ethnicity, diabetes, and hypertension, 993 patients were included per group. Kaplan-Meier survival analysis assessed antimicrobial and opioid use, resistance, and opioid abuse or dependence.</div></div><div><h3>Results</h3><div>Mean follow-up was significantly longer in the sacrocolpopexy group (7.67 ± 4.66 years) than in the hysterectomy group (3.13 ± 4.23 years). Hysterectomy patients experienced a higher mean number of postoperative complications although these results were not statistically significant (p = 0.0688). Postoperative antimicrobial use was significantly higher in the hysterectomy group (25.9 %) than sacrocolpopexy (14.1 %) (HR 3.84, 95 % CI: 2.99–4.93; p &lt; 0.0001). Opioid use was also more frequent in hysterectomy patients (44.4 % vs. 15.6 %; HR 5.68, 95 % CI: 4.69–6.88; p &lt; 0.0001), with a higher incidence of abuse/dependence (6.04 % vs. 2.02 %; HR 6.91, 95 % CI: 4.07–11.73). No significant difference was observed in antimicrobial resistance (p = 0.4409). Paralytic ileus was rare and not significantly different between groups.</div></div><div><h3>Conclusion</h3><div>Hysterectomy was associated with greater risk of postoperative opioid use, opioid abuse/dependence, and antimicrobial use. These findings support individualized surgical planning and proactive postoperative management.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"28 ","pages":"Article 100433"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145466711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Guidance Paper VVOG: Pharmacological treatment of endometriosis-related pain","authors":"Ellen Remans ,&nbsp;Celine Bafort ,&nbsp;Celine Blank ,&nbsp;Alex Bongima ,&nbsp;Brecht Geysenbergh ,&nbsp;Tjalina Hamerlynck ,&nbsp;Geert Page ,&nbsp;Jasper Verguts ,&nbsp;Carla Tomassetti","doi":"10.1016/j.eurox.2025.100403","DOIUrl":"10.1016/j.eurox.2025.100403","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100403"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144685726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of clinical usability and reproducibility of the American Society for Reproductive Medicine Müllerian Anomalies Classification","authors":"Julia Lastinger ,&nbsp;Natalia Palasz ,&nbsp;Peter Oppelt ,&nbsp;Galymzhan Toktarbekov ,&nbsp;Milan Terzic ,&nbsp;Raimund Stein ,&nbsp;Katharina Rall ,&nbsp;Helga Wagner ,&nbsp;Philipp Hermann ,&nbsp;Stephanie Kiblboeck","doi":"10.1016/j.eurox.2025.100425","DOIUrl":"10.1016/j.eurox.2025.100425","url":null,"abstract":"<div><h3>Objective</h3><div>To study the usability, reproducibility and practicality of the revised American Society for Reproductive Medicine Müllerian Anomalies Classification (ASRM MAC2021) compared to the formerly used American Fertility Society (AFS) classification. The main focus of this paper is to present clinicians’ assessment when using these classification systems and to explore possible benefits and disadvantages of the transformation of the AFS into the more recently published ASRM classification. To incorporate all commonly used classification systems, all cases were additionally classified using the ESHRE/ESGE and the VCUAM classification.</div></div><div><h3>Methods</h3><div>An observational study using a questionnaire and opinion survey was conducted with the goal of comparing clinicians’ subjective usability and reproducibility of the AFS classification with the newly presented ASRM MAC2021 classification. Cases of female genital malformations encompassed a wide range of various anomalies, including vaginal, cervical and adnexal conditions and associated malformations.</div></div><div><h3>Results</h3><div>The study investigators rated the ASRM MAC2021 classification better in relation to usability and reproducibility compared to the AFS classification. It significantly improved diagnostic precision for vaginal and cervical anomalies and expanded recognition of adnexal malformations. However, challenges remain in addressing associated malformations. Clinicians ranked the ASRM MAC2021 higher than the AFS classification. However, investigators rated the ESHRE/ESGE and VCUAM classifications better in the overall assessment of female genital malformations.</div></div><div><h3>Conclusion</h3><div>The ASRM MAC2021 classification offers substantial improvements in diagnosing and managing female genital malformations, addressing limitations of the AFS system. With better usability and subjective reproducibility, further refinements are needed to fully address complex associated anomalies — emphasizing the importance of evolving classification systems.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100425"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145004268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of life, sexual function and metabolic parameters of women during 10 years of using the etonogestrel implant","authors":"Salvatore Caruso ,&nbsp;Angelo Cagnacci ,&nbsp;Giuseppe Caruso ,&nbsp;Stefano Cianci ,&nbsp;Marco Palumbo","doi":"10.1016/j.eurox.2025.100421","DOIUrl":"10.1016/j.eurox.2025.100421","url":null,"abstract":"<div><h3>Objective</h3><div>To study the effects on the quality of life (QoL), sexual function and metabolic aspects in women using a subcutaneous implant containing Etonogestrel (ENG-implant) over 10 years of observation period.</div></div><div><h3>Study design</h3><div>This study was performed from January 2011 to September 2023. A database was set up to collect data from women. Counseling on the ENG-implant to be inserted at the termination of pregnancy, and on insert a new device every 3 years was adopted. The Short Form-36 (SF-36), the Female Sexual Function Index (FSFI) and the Female Sexual Distress Scale (FSDS) questionnaires were used to investigate the QoL, sexual function and sexual distress, respectively, of women at baseline and at 6, 12, 24, 36, 72 and 108-month follow-ups. Blood samples were collected from women to measure metabolic parameters.</div></div><div><h3>Results</h3><div>32 of 52 (61.5 %) enrolled women completed the study. In summary, after removing the first (at 36th month of use) and the second implant (at 72nd month of use), 44 (84.6 %) and 32 (61.5 %) women asked for the insertion of a new device, respectively. Somatic (p &lt; 0.001) and mental (p = 0.04) categories of SF-36 improved from the 12-month follow-up to the 108-month follow-up (p &lt; 0.001). FSFI scores also increased from 12-month follow-up to the 108-month follow-up (p &lt; 0.001). The improvement of the total scores depended on the gradual increase in each FSFI item (p &lt; 0.001).</div><div>FSDS score became statistically significant starting from the 12-month follow-up to the 108-month follow-up (p &lt; 0.001). Although lipid metabolism, fasting glucose, liver function and hemostatic parameters were slightly reduced, they remained within the range of the normal values.</div></div><div><h3>Conclusions</h3><div>The long observation period of 10 years allowed us to state that the ENG-implant could have neutral effects on metabolic parameters, promote a better quality of life, and improve sexuality in the users. The main limitation of our study was the small number of women enrolled, mainly due to the cost of the implant. These results should be confirmed on a larger sample.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100421"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144810380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical guidance paper VVOG primary and secondary prevention of preterm birth in singleton pregnancies","authors":"François Emilia ,&nbsp;Kouloujian Laurence ,&nbsp;Langermans Lisa-Marie ,&nbsp;Mannaerts Dominique ,&nbsp;Nulens Katrien ,&nbsp;Page Geert ,&nbsp;Ponnet Sophie ,&nbsp;Scheire Eline ,&nbsp;Van Holsbeke Caroline ,&nbsp;Dehaene Isabelle","doi":"10.1016/j.eurox.2025.100401","DOIUrl":"10.1016/j.eurox.2025.100401","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100401"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144261906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical guidance paper VVOG HPV vaccination in women undergoing conisation for CIN2 + lesions to prevent recurrence.","authors":"Stephanie Orye ,&nbsp;Saliha Hamici ,&nbsp;Fabian Desimpel ,&nbsp;Sander Dumont ,&nbsp;Ruben Heremans ,&nbsp;Babette Jaime Moens ,&nbsp;Geert Page ,&nbsp;Eline Salaets ,&nbsp;Rawand Salihi ,&nbsp;Adriaan Vanderstichele ,&nbsp;Kobe Dewilde","doi":"10.1016/j.eurox.2025.100404","DOIUrl":"10.1016/j.eurox.2025.100404","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100404"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144261907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison between laparoscopy and hysteroscopy approaches in the treatment of symptomatic isthmocele: A systematic review and meta-analysis","authors":"Zahra Ramezani ,&nbsp;Saba Goodarzi ,&nbsp;Pegah Rashidian ,&nbsp;Shima Mohammadian ,&nbsp;Hadis Rastad ,&nbsp;Mona Esmi ,&nbsp;Arman Shafiee ,&nbsp;Mahmood Bakhtiyari","doi":"10.1016/j.eurox.2025.100405","DOIUrl":"10.1016/j.eurox.2025.100405","url":null,"abstract":"<div><h3>Objective</h3><div>To compare the clinical outcomes of laparoscopy and hysteroscopy in the treatment of symptomatic isthmocele using a systematic review and meta-analysis.</div></div><div><h3>Methods</h3><div>A comprehensive search of PubMed, Scopus, and Web of Science was performed until November 11, 2024. Studies evaluating outcomes of laparoscopy or hysteroscopy intervention for treating symptomatic isthmocele were included in this study. A random-effects model was employed for heterogeneous data. The study is registered in PROSPERO with registration number CRD420251028603.</div></div><div><h3>Results</h3><div>Nine studies involving 797 patients were included. Hysteroscopy demonstrated significantly less intraoperative blood loss (SMD: −2.28, 95 % CI: −3.65 to −0.90) and shorter hospital stays (SMD: −2.62, 95 % CI: −3.52 to −1.72), but the operative time difference was non-significant. Both approaches were equally effective in symptom resolution and defect repair (OR: 0.80, 95 % CI: 0.21–2.97). However, laparoscopic repair was associated with better outcomes for dysmenorrhea improvement (OR: 3.46, 95 % CI: 1.42–8.45) and higher postoperative pregnancy rates (OR: 4.17, 95 % CI: 1.89–9.09). High heterogeneity was noted in some outcomes, reflecting variability in study designs and populations.</div></div><div><h3>Conclusions</h3><div>Both laparoscopy and hysteroscopy are effective in treating symptomatic isthmocele, with each approach offering distinct advantages. Hysteroscopy is less invasive with faster recovery and better fertility.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100405"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144321595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical guidance VVOG: Antenatal care for twin pregnancies","authors":"Senna van der Heijden ,&nbsp;Noortje van Oostrum ,&nbsp;Roxanne Van Nuland ,&nbsp;Magali Verheecke ,&nbsp;Liesbeth Lewi","doi":"10.1016/j.eurox.2025.100414","DOIUrl":"10.1016/j.eurox.2025.100414","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100414"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144679177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measuring woman’s perception of support and control during childbirth: Psychometric proprieties of the SCIB scale in an Italian sample","authors":"Sara Molgora ,&nbsp;Federica Bonazza ,&nbsp;Maurizio Barbieri Carones ,&nbsp;Enrico Maria Ferrazzi ,&nbsp;Elizabeth Ford","doi":"10.1016/j.eurox.2025.100424","DOIUrl":"10.1016/j.eurox.2025.100424","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to develop an Italian version of the Support and Control in Birth (SCIB) and to test its reliability and validity.</div></div><div><h3>Methods</h3><div>The sample included 414 post-partum women, who were recruited 24/48 h after giving birth. A study-specific online questionnaire was designed to collect sociodemographic information and administer the translated Italian version of the SCIB. The construct validity of the Italian SCIB was first analyzed using Confirmatory Factor Analysis (CFA). Based on metrics showing a poor fit, Exploratory Factor Analysis (EFA) was then executed. The reliability of the instrument was verified through Cronbach’s alpha for each subscale and the total scale and test-retest correlation coefficient.</div></div><div><h3>Results</h3><div>CFA was performed to test the original three-factor theoretical model; however, the CFA solution showed a poor fit. Specifically, χ2 = 2100, df= 492, p &lt; 0.001, RMSEA = 0.0888 (0.085 – 0.0928), and CFI = 0.45. The theoretical model did not adequately fit the observed data. Thus, EFA was conducted; it yielded a six-factor structure. The six factors were named: Support: healthcare professionals’ guidance; Support: healthcare professionals’ presence; External control: control over medical procedures; External control: control over the informational process; Internal control: control over emotional and physical reactions; Internal control: control over pain. These factors replicate the originals dimensions, each divided into two further subfactors.</div></div><div><h3>Conclusion</h3><div>Findings enhance knowledge about childbirth by cross-culturally adapting an instrument to assess perceptions of control and support, fundamental factors in birth experience. SCIB could help health professionals to monitor women's childbirth experiences and introduce tailored interventions.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100424"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144903718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}