European Journal of Obstetrics and Gynecology and Reproductive Biology: X最新文献

{"title":"Stress-induced developmental plasticity and spontaneous preterm birth: A justice-oriented eco-evo-devo review","authors":"Gabriella Mayne ,&nbsp;Luwam Ghidei ,&nbsp;Ayisha Buckley ,&nbsp;Wei Perng ,&nbsp;K. Joseph Hurt ,&nbsp;David P. Tracer","doi":"10.1016/j.eurox.2025.100409","DOIUrl":"10.1016/j.eurox.2025.100409","url":null,"abstract":"<div><div>Spontaneous preterm birth (&lt;37 weeks’ gestation) is a leading cause of neonatal morbidity and mortality, with little global progress in prevention. Spontaneous preterm birth disproportionately affects communities marginalized by racism and socio-economic disadvantage. Maternal stress is a well-established risk factor for spontaneous preterm birth and is more prevalent in marginalized communities. Yet, maternal stress remains underutilized as a target for clinical intervention. In this review, we draw from ecological, evolutionary, and developmental (eco-evo-devo) biology, Black feminist theory, and reproductive justice to center the margins of those communities most burdened by both maternal stress and preterm birth. In doing so, we re-frame the importance of maternal stress mitigation in spontaneous preterm prevention. Through the lens of stress-induced developmental plasticity, environmental stressors may shorten gestation through evolutionarily conserved maternal-fetal-placental signaling pathways. Two features of this process are particularly relevant to clinical care: first, stress may impact gestational length in a dose-dependent manner; second, its effects may be reversible. Reducing maternal stress may be a highly feasible clinical opportunity to tangibly reduce spontaneous preterm birth and increase birth equity.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100409"},"PeriodicalIF":1.5,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144261910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison between laparoscopy and hysteroscopy approaches in the treatment of symptomatic isthmocele: A systematic review and meta-analysis","authors":"Zahra Ramezani ,&nbsp;Saba Goodarzi ,&nbsp;Pegah Rashidian ,&nbsp;Shima Mohammadian ,&nbsp;Hadis Rastad ,&nbsp;Mona Esmi ,&nbsp;Arman Shafiee ,&nbsp;Mahmood Bakhtiyari","doi":"10.1016/j.eurox.2025.100405","DOIUrl":"10.1016/j.eurox.2025.100405","url":null,"abstract":"<div><h3>Objective</h3><div>To compare the clinical outcomes of laparoscopy and hysteroscopy in the treatment of symptomatic isthmocele using a systematic review and meta-analysis.</div></div><div><h3>Methods</h3><div>A comprehensive search of PubMed, Scopus, and Web of Science was performed until November 11, 2024. Studies evaluating outcomes of laparoscopy or hysteroscopy intervention for treating symptomatic isthmocele were included in this study. A random-effects model was employed for heterogeneous data. The study is registered in PROSPERO with registration number CRD420251028603.</div></div><div><h3>Results</h3><div>Nine studies involving 797 patients were included. Hysteroscopy demonstrated significantly less intraoperative blood loss (SMD: −2.28, 95 % CI: −3.65 to −0.90) and shorter hospital stays (SMD: −2.62, 95 % CI: −3.52 to −1.72), but the operative time difference was non-significant. Both approaches were equally effective in symptom resolution and defect repair (OR: 0.80, 95 % CI: 0.21–2.97). However, laparoscopic repair was associated with better outcomes for dysmenorrhea improvement (OR: 3.46, 95 % CI: 1.42–8.45) and higher postoperative pregnancy rates (OR: 4.17, 95 % CI: 1.89–9.09). High heterogeneity was noted in some outcomes, reflecting variability in study designs and populations.</div></div><div><h3>Conclusions</h3><div>Both laparoscopy and hysteroscopy are effective in treating symptomatic isthmocele, with each approach offering distinct advantages. Hysteroscopy is less invasive with faster recovery and better fertility.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100405"},"PeriodicalIF":1.5,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144321595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Focused ultrasound treatment of cervical human papillomavirus infection and squamous intraepithelial lesions: A narrative review","authors":"Vincent Y.T. Cheung","doi":"10.1016/j.eurox.2025.100406","DOIUrl":"10.1016/j.eurox.2025.100406","url":null,"abstract":"<div><div>Focused ultrasound (FUS) appears to be a promising form of thermal ablation for treatment of cervical lesions, but evidence supporting its use is limited. This review evaluated the efficacy and safety of FUS treatment of cervical human papillomavirus (HPV) infection and squamous intraepithelial lesions (SIL). The overall efficacy of FUS on HPV clearance was 75.0–85.7 % at 3 months, 35.5–77.1 % at 6 months and 64.7–94.1 % at 12 months. Its efficacy on low grade SIL and high grade SIL regression were 83.3–96.8 % and 70.9–96.6 % at 6 months, respectively. Complications were uncommon. FUS appears to be an effective and safe treatment modality for cervical HPV and SIL.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"26 ","pages":"Article 100406"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144230490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cesarean Scar Pregnancy: Three case reports and literature review","authors":"Esther Ruiz Pérez ,&nbsp;Cristina Álvarez Colomo ,&nbsp;Victoria Pascual Escudero ,&nbsp;Álvaro Sanz Díaz-Heredero ,&nbsp;Lidia Casamayor Del Nogal ,&nbsp;Marta Ibáñez Nieto ,&nbsp;Sandra Canales Martínez ,&nbsp;Jimena Bayón Pascual ,&nbsp;Mónica Simón de la Fuente ,&nbsp;Mónica Consuelo Horstmann Sendagorta","doi":"10.1016/j.eurox.2025.100407","DOIUrl":"10.1016/j.eurox.2025.100407","url":null,"abstract":"<div><h3>Introduction</h3><div>Cesarean Scar Pregnancy (CSP) is defined as an ectopic pregnancy in which the gestational sac implants on the surgical scar of a previous cesarean section or isthmocele.</div><div>Despite its low incidence, the diagnosis presents a significant difficulty, and a false negative diagnosis can lead to serious complications that may require more aggressive treatments.</div></div><div><h3>Objective</h3><div>The main objective of this study is to present three clinical cases of patients with suspected ectopic pregnancy in the cesarean scar, including a review of the current literature on this condition.</div></div><div><h3>Methods</h3><div>The clinical case data were obtained from the patients’ medical records, including the results of the additional tests performed, as well as subsequent gynecology appointments. On the other hand, a literature review was conducted on ectopic pregnancies in the cesarean scar.</div></div><div><h3>Results</h3><div>During ultrasound examinations of patients with a history of previous cesarean sections, special attention should be paid to identifying the implantation site of the gestational sac to rule out CSP.</div><div>Due to the limited number of trials and case reports on CSP, there is no consensus on standardized treatment and management. The primary goal is to preserve patient's fertility and avoid severe complications such as massive hemorrhage or uterine rupture.</div></div><div><h3>Conclusions</h3><div>Cesarean Scar Pregnancy (CSP) should be considered among the diagnostic options when finding a gestational sac located in atypical situations in patients with a history of cesarean section.</div><div>Early diagnosis and treatment are crucial for achieving the best outcomes. A minimally invasive approach should be planned as first-line treatment in all situations where CSP is included in the differential diagnosis.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"26 ","pages":"Article 100407"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144204231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends and characteristics of triplet births in a tertiary maternity hospital in China: A retrospective study over two decades","authors":"Yanzhen Zhou,&nbsp;Jinxiu Lin,&nbsp;Zhaozhen Liu,&nbsp;Sheng Lin","doi":"10.1016/j.eurox.2025.100394","DOIUrl":"10.1016/j.eurox.2025.100394","url":null,"abstract":"<div><h3>Background</h3><div>As triplet pregnancies were usually associated with poorer pregnancy outcomes and fetal reduction was coupled with procedure-related complications, many women with triplet pregnancies often opted for expectant management. This retrospective study reported the pregnancy outcomes of women with triplet pregnancies who did not receive artificial fetal reduction over a two-decade period (2002-2021).</div></div><div><h3>Methods</h3><div>Maternal and pregnancy data and perinatal outcomes, including 111 triplets, were obtained from women with triplet pregnancies who received expectant management at Fujian Maternity and Child Health Hospital, including 111 triplets. The patient cohort was divided into two subgroups(Period I, 2002-2011 vs. Period II, 2012-2021).</div></div><div><h3>Results</h3><div>Compared with those in the Period I group, participants in the Period II group reported a better educational background (28.8 vs. 13.8 %, p = 0.024), and occupation status (40.4 vs. 20.6 %, p = 0.012) and a greater percentage of primiparas (57.7 vs. 5.1 %, p &lt; 0.005). However, compared with those in the Period II group, the period I group displayed significantly older gestation age at delivery(p = 0.001), heavier mean birth weight(1583.63 ± 62.14 vs.1830.51 ± 41.95 kg), higher rate of babies taken home(91.6 vs. 84.2 %,p = 0.049), and lower NICU admission rate(47.0 vs. 77.5 %, p &lt; 0.005).</div></div><div><h3>Conclusions</h3><div>Due attention to triplet pregnancies might lower the rate of maternity complications, and antenatal medicines to prevent prematurity could not prolong birth week. Developed neonatal treatment and nursing are adapted to stratified management based on chorionicity. With advancements in maternal healthcare and neonatal treatment, and nursing, expectant management could be a considerable option. Maternal factors such as parity and maternal education status might be correlated with gestational age.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"26 ","pages":"Article 100394"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144223371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Guidance Paper VVOG: Pharmacological treatment of endometriosis-related pain","authors":"Ellen Remans ,&nbsp;Celine Bafort ,&nbsp;Celine Blank ,&nbsp;Alex Bongima ,&nbsp;Brecht Geysenbergh ,&nbsp;Tjalina Hamerlynck ,&nbsp;Geert Page ,&nbsp;Jasper Verguts ,&nbsp;Carla Tomassetti","doi":"10.1016/j.eurox.2025.100403","DOIUrl":"10.1016/j.eurox.2025.100403","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100403"},"PeriodicalIF":1.5,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144685726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical guidance paper VVOG HPV vaccination in women undergoing conisation for CIN2 + lesions to prevent recurrence.","authors":"Stephanie Orye ,&nbsp;Saliha Hamici ,&nbsp;Fabian Desimpel ,&nbsp;Sander Dumont ,&nbsp;Ruben Heremans ,&nbsp;Babette Jaime Moens ,&nbsp;Geert Page ,&nbsp;Eline Salaets ,&nbsp;Rawand Salihi ,&nbsp;Adriaan Vanderstichele ,&nbsp;Kobe Dewilde","doi":"10.1016/j.eurox.2025.100404","DOIUrl":"10.1016/j.eurox.2025.100404","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100404"},"PeriodicalIF":1.5,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144261907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical guidance paper VVOG primary and secondary prevention of preterm birth in singleton pregnancies","authors":"François Emilia ,&nbsp;Kouloujian Laurence ,&nbsp;Langermans Lisa-Marie ,&nbsp;Mannaerts Dominique ,&nbsp;Nulens Katrien ,&nbsp;Page Geert ,&nbsp;Ponnet Sophie ,&nbsp;Scheire Eline ,&nbsp;Van Holsbeke Caroline ,&nbsp;Dehaene Isabelle","doi":"10.1016/j.eurox.2025.100401","DOIUrl":"10.1016/j.eurox.2025.100401","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100401"},"PeriodicalIF":1.5,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144261906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Withdrawal notice to “Could blastocysts derived from abnormal fertilized zygotes be used? A systematic review and meta-analysis” [Eur J Obstet Gynecol Reprod Biol X 26C (2025) 100381]","authors":"Yiqing Wu ,&nbsp;Jinglei Xue ,&nbsp;Mixue Tu ,&nbsp;Yifeng Liu ,&nbsp;Dan Zhang","doi":"10.1016/j.eurox.2025.100396","DOIUrl":"10.1016/j.eurox.2025.100396","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"26 ","pages":"Article 100396"},"PeriodicalIF":1.5,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144169918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iron deficiency anaemia (IDA) in pregnancy: Screening and management","authors":"Virginie De Moor ,&nbsp;Tinne Mesens ,&nbsp;Soetkin Soulliaert ,&nbsp;Hannes van der Merwe ,&nbsp;Simen Vergote ,&nbsp;Magali Verheecke ,&nbsp;Geert Page ,&nbsp;Liesbeth Lewi","doi":"10.1016/j.eurox.2025.100402","DOIUrl":"10.1016/j.eurox.2025.100402","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100402"},"PeriodicalIF":1.5,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144271247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}