European Journal of Obstetrics and Gynecology and Reproductive Biology: X最新文献

{"title":"Treatment strategies for intra-amniotic infection and/or inflammation in preterm labor cases","authors":"Satoshi Yoneda ,&nbsp;Noriko Yoneda ,&nbsp;Hideki Niimi ,&nbsp;Shigeru Saito","doi":"10.1016/j.eurox.2025.100408","DOIUrl":"10.1016/j.eurox.2025.100408","url":null,"abstract":"<div><div>Spontaneous preterm birth (sPTB) is caused by multiple factors; however, the main cause is intra-amniotic infection and/or inflammation. The frequency of intra-amniotic infection/inflammation is higher in extremely sPTB (&lt;28 weeks) and causes long-term cognitive impairments, such as cerebral palsy and mental retardation. The rate of intra-amniotic superinfections, such as <em>Ureaplasma</em>/<em>Mycoplasma</em> and bacteria, is high in sPTB &lt; 27 weeks of gestation. Obstetrical strategies based on accurate information on intra-amniotic infection/inflammation are needed to prevent sPTB (particularly extremely sPTB) and improve the long-term prognosis of preterm infants. Our PCR method, which is sensitive and free from false positives, accurately identifies whether intra-amniotic infection is present. Appropriate antibiotic therapy against intra-amniotic infection (macrolides against <em>Ureaplasma</em>/<em>Mycoplasma</em> and beta-lactams against bacteria) in preterm labor (PTL) cases effectively prolongs the gestational period by 4 weeks. In contrast, the use of antibiotics shortens the gestational period in cases without intra-amniotic infection. We previously reported that 17-alpha-hydroxyprogesterone caproate (17OHP-C) effectively prolonged pregnancy by 4 weeks in PTL cases with mild intra-amniotic inflammation, but not in those with severe intra-amniotic inflammation. Treatment strategies based on accurate intra-amniotic information is expected to prolong pregnancy. However, obstetrical interventions are limited once severe clinical symptoms appear. In addition to the use of drugs to control uterine contractions, antibiotics and/or 17OHP-C may be necessary in the treatment of PTL cases following the accurate assessment of intrauterine infection and/or inflammation is confirmed.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100408"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144290482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical guidance paper VVOG-CRGOLFB prevention and management of obstetrical perineal trauma","authors":"Marit Iliaens ,&nbsp;Esther Van Elslander ,&nbsp;Elien Baert ,&nbsp;Emma Bauters ,&nbsp;Lauren Becu ,&nbsp;Laurent de Landsheere ,&nbsp;Katrien De Maeyer ,&nbsp;Charlotte Deltour ,&nbsp;Inge Geraerts ,&nbsp;Susanne Housmans ,&nbsp;Elise Maes ,&nbsp;Mathilde Maskens ,&nbsp;Tinne Mesens ,&nbsp;Bram Packet ,&nbsp;Ann-Sophie Page ,&nbsp;Geert Page ,&nbsp;Inge Tency ,&nbsp;Bart Vergauwe ,&nbsp;Ann Pastijn","doi":"10.1016/j.eurox.2025.100416","DOIUrl":"10.1016/j.eurox.2025.100416","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100416"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144611656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suprapubic pressure: A marker of cervical insufficiency? A case report","authors":"Athina Efthymiou,&nbsp;Effrosyni Birbas,&nbsp;Theofilos Kanavos,&nbsp;Charikleia Skentou,&nbsp;Nadia Almousa,&nbsp;George Makrydimas","doi":"10.1016/j.eurox.2025.100411","DOIUrl":"10.1016/j.eurox.2025.100411","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100411"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144321594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vaginal NOTES adnexal surgery: Results of a retrospective cohort study in The Netherlands","authors":"Rebecca Henschen ,&nbsp;Anouk J.M. Bus ,&nbsp;Nicol A.C. Smeets ,&nbsp;Marlies Y. Bongers ,&nbsp;Martine M.L.H. Wassen","doi":"10.1016/j.eurox.2025.100422","DOIUrl":"10.1016/j.eurox.2025.100422","url":null,"abstract":"<div><h3>Objective</h3><div>Vaginal natural orifice transluminal endoscopy (vNOTES) is a minimally invasive technique gaining popularity for several gynaecological procedures. This study presents the first 81 adnexal cases, performed in The Netherlands.</div></div><div><h3>Design, setting, participants, and intervention</h3><div>This retrospective cohort study included patients who underwent vNOTES adnexal surgery for benign indications at Zuyderland Medical Centre between March 2020 and August 2024. Baseline characteristics, surgical outcomes, and per- and postoperative outcomes were analysed. Two expert vaginal and endoscopic gynaecological surgeons performed all procedures.</div></div><div><h3>Results</h3><div>A total of 81 patients underwent adnexal surgery using vNOTES. Indications were definitive contraception (60.5 %; n = 49), ovarian cysts (18.5 %; n = 15), risk-reducing surgery for gene mutation carriers (16.0 %; n = 13), ectopic pregnancy (3.7 %; n = 3), and request for artificial menopause due to complaints (1.2 %; n = 1). Procedures performed were bilateral salpingectomy (60.5 %; n = 49), bilateral salpingo-oophorectomy (28.4 %; n = 23), unilateral salpingo-oophorectomy (4.9 %; n = 4), unilateral salpingectomy (3.7 %; n = 3), unilateral ovariectomy (1.2 %; n = 1), and unilateral salpingo-oophorectomy with unilateral salpingectomy (1.2 %; n = 1). The mean surgical time was 38.7 min (SD 17.9 min), with a mean blood loss of 26 mL (SD 42.4 mL). There was one (1.2 %) conversion to laparoscopy, and two (2.5 %) intra-operative complications without re-interventions. Most patients (88.8 %) were treated in a day-care setting. Four postoperative complications (4.9 %) were reported within six weeks after surgery.</div></div><div><h3>Conclusion</h3><div>This study shows that vNOTES is a safe and feasible, less invasive and scarless alternative to laparoscopic and open surgery for benign adnexal pathology. More evidence is needed to compare vNOTES adnexal surgery with laparoscopy.</div></div><div><h3>Summation</h3><div>vNOTES is a safe and feasible, less invasive alternative without abdominal scars compared to laparoscopic and open abdominal surgery for benign adnexal pathology.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100422"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144810379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iron deficiency anaemia (IDA) in pregnancy: Screening and management","authors":"Virginie De Moor ,&nbsp;Tinne Mesens ,&nbsp;Soetkin Soulliaert ,&nbsp;Hannes van der Merwe ,&nbsp;Simen Vergote ,&nbsp;Magali Verheecke ,&nbsp;Geert Page ,&nbsp;Liesbeth Lewi","doi":"10.1016/j.eurox.2025.100402","DOIUrl":"10.1016/j.eurox.2025.100402","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100402"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144271247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimal standard of care for medically indicated termination of pregnancy","authors":"Lore De Meulenaer ,&nbsp;Tessa Van Steenstraeten ,&nbsp;Hilde Logghe ,&nbsp;Tinne Mesens ,&nbsp;Geert Page ,&nbsp;Kristien Roelens ,&nbsp;Eve Van den Mooter ,&nbsp;Magali Verheecke ,&nbsp;Ellen Roets","doi":"10.1016/j.eurox.2025.100413","DOIUrl":"10.1016/j.eurox.2025.100413","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100413"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144580078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic workup for a couple with unexplained infertility – VVOG guidance","authors":"Nouhaïla Abbib ,&nbsp;Anna Heylen ,&nbsp;Sara Neyens ,&nbsp;Geert Page ,&nbsp;Elke Stevens ,&nbsp;Arne Vanhie ,&nbsp;Helena Van Kerrebroeck ,&nbsp;Nathalie Dhont","doi":"10.1016/j.eurox.2025.100415","DOIUrl":"10.1016/j.eurox.2025.100415","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100415"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144580079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contraceptive use among post-abortion women in France: A quantitative study","authors":"Matthieu Calafiore ,&nbsp;Charlotte Lebreton ,&nbsp;Judith Ollivon ,&nbsp;Marc Bayen ,&nbsp;Nassir Messaadi ,&nbsp;Sabine Bayen","doi":"10.1016/j.eurox.2025.100419","DOIUrl":"10.1016/j.eurox.2025.100419","url":null,"abstract":"<div><h3>Background</h3><div>Voluntary termination of pregnancy (VTP) is a subject of ongoing debate throughout the world. The number of abortions continues to rise each year, with 234,300 recorded in France in 2022. This study aims to quantitatively assess changes in contraceptive methods before and after abortion among women in the Hauts-de-France region with a view to improving their care, promoting their sexual well-being and reducing the number of repeat abortions.</div></div><div><h3>Method</h3><div>A quantitative, retrospective, descriptive study was carried out using the records of women followed up by general practitioners in Hauts-de-France. The study ran from 15 March 2024–3 September 2024.</div></div><div><h3>Results</h3><div>A total of 63 questionnaires were analysed. Most participants were women aged between 26 and 35, living with a partner. Before the abortion, 56.3 % of the women were not using any contraception. After the abortion, 70.5 % of women changed their contraceptive method immediately, and 25 % did so within six months of the abortion. After the abortion and at 6 months, the results were stable overall, with most women choosing Long-Acting Reversible Contraception, but 11 % (n = 7) remaining without any contraception. Of the participants, 12 % (n = 7) had a repeat abortion, of whom 4 were using the pill, 1 was on a copper IUD, and 2 were not using any contraception.</div></div><div><h3>Conclusion</h3><div>After an abortion, most women opt for a contraceptive method, mainly implants and IUDs. It is important that every woman receives adequate information to make informed choices about family planning.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100419"},"PeriodicalIF":1.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144724981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety of hormonal IUD in breast cancer patients","authors":"Coeman Hanne ,&nbsp;Foulon Aurélie ,&nbsp;Amajoud Zainab ,&nbsp;Decloedt Jan ,&nbsp;Delporte Femke ,&nbsp;Van Houdt Maxime ,&nbsp;Page Geert ,&nbsp;Van Berckelaer Christophe","doi":"10.1016/j.eurox.2025.100412","DOIUrl":"10.1016/j.eurox.2025.100412","url":null,"abstract":"","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100412"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144580080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trigonometric characteristics of episiotomy & pregnancy variables","authors":"Richa Chouksey ,&nbsp;Sai Snehitha Veluguleti ,&nbsp;Deeksha Pandey","doi":"10.1016/j.eurox.2025.100418","DOIUrl":"10.1016/j.eurox.2025.100418","url":null,"abstract":"<div><h3>Introduction</h3><div>Episiotomy, though simple and most common surgical procedure performed in labour theatre, has a lot of bearing on patients’ recovery postpartum. The episiotomy angle and length can influence probability of anal sphincter trauma, ease of delivery and post-delivery recovery in variable ways. We hypothesize that a universal measure of angle (60°) and length might not be ideal for all women. This aim of this cohort study was to establish association of episiotomy trigonometric characteristics (length and angle) with antepartum, intrapartum and postpartum factors.</div></div><div><h3>Material &amp; methods</h3><div>A total of 504 pregnant women who delivered with an episiotomy after 34 weeks of gestation were included. Antenatal, intrapartum, and postpartum variables were collated. These women were examined for episiotomy length, angle, signs of infection/inflammation and pain using Visual Analogue Scale (VAS). All of them were followed up till they were discharged frm the hospital.</div></div><div><h3>Results</h3><div>A smaller episiotomy angle (&lt;15°) was associated with significantly higher VAS score as compared to angle 35°-40°. We observed that as birth weight increases, mean episiotomy length and angle progressively increases. Longer head circumference was associated with longer length of episiotomies (p &lt; 0.01). Instrumental deliveries were associated with higher length and angle of episiotomy.</div></div><div><h3>Conclusion</h3><div>We observed a relationship of trigonometric characteristics of episiotomy with variables like birth weight and HC. We feel the angle and length of episiotomy cannot be defined as a universal constant. It depends of maternal and fetal variables. We propose that episiotomy should be tailored for every patient to achieve the most optimal result for her.</div></div><div><h3>Synopsis</h3><div>This study reflects episiotomy practice at a tertiary care hospital. We must conduct larger studies to evaluate variables that influence the trigonometric characteristics of episiotomy.</div></div>","PeriodicalId":37085,"journal":{"name":"European Journal of Obstetrics and Gynecology and Reproductive Biology: X","volume":"27 ","pages":"Article 100418"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144589209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}