Medicina Clinica Practica最新文献

Plexopatía sacra posherpética en el adulto mayor 成人带状疱疹后骶神经丛病

Medicina Clinica Practica Pub Date : 2026-07-01 Epub Date: 2026-07-14 DOI: 10.1016/j.mcpsp.2026.100549

Yanira Aranda Rubio, Cristina Resino Luis, Pilar López Esteban

引用次数: 0

Cervical sympathetic chain schwannomas: a five-case series with diagnostic and surgical insights 颈交感链神经鞘瘤：五例诊断和手术见解

Medicina Clinica Practica Pub Date : 2026-07-01 Epub Date: 2026-06-19 DOI: 10.1016/j.mcpsp.2026.100548

Santiago Almanzo, Sara Iommi-Diez, José María Perolada-Valmaña, Miguel Armengot-Carceller

{"title":"Cervical sympathetic chain schwannomas: a five-case series with diagnostic and surgical insights","authors":"Santiago Almanzo, Sara Iommi-Diez, José María Perolada-Valmaña, Miguel Armengot-Carceller","doi":"10.1016/j.mcpsp.2026.100548","DOIUrl":"10.1016/j.mcpsp.2026.100548","url":null,"abstract":"<div><div>Cervical sympathetic chain schwannomas (CSCS) are rare benign carotid space tumors that are often difficult to diagnose preoperatively because of their deep location and proximity to major vessels. We retrospectively reviewed five patients with histologically confirmed CSCS treated at a tertiary referral center between 2016 and 2024. Inclusion criteria were histopathological confirmation, preoperative magnetic resonance imaging (MRI), surgical treatment at our institution, and at least 12 months of follow-up. Patients without histological confirmation, complete MRI evaluation, treatment at our institution, or adequate follow-up were excluded. Three patients showed the classic MRI pattern of anterior displacement of the carotid artery and internal jugular vein without separation, whereas two showed atypical vascular displacement. Complete excision was achieved in all cases. One patient developed permanent Horner's syndrome. No recurrences were observed after 12–108 months of follow-up. CSCS should be considered in carotid space masses with vessel displacement on MRI. Awareness of both typical and atypical imaging patterns may improve diagnosis, surgical planning, and preoperative counseling.</div></div>","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":"9 3","pages":"Article 100548"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unilateral vestibular loss following systemic gentamicin: A rare complication with clinical relevance 全身庆大霉素后单侧前庭功能丧失：具有临床意义的罕见并发症

Medicina Clinica Practica Pub Date : 2026-07-01 Epub Date: 2026-07-14 DOI: 10.1016/j.mcpsp.2026.100550

Santiago Almanzo, Sara Iommi-Diez, Miguel Armengot-Carceller, Vanesa Pérez-Guillén

{"title":"Unilateral vestibular loss following systemic gentamicin: A rare complication with clinical relevance","authors":"Santiago Almanzo, Sara Iommi-Diez, Miguel Armengot-Carceller, Vanesa Pérez-Guillén","doi":"10.1016/j.mcpsp.2026.100550","DOIUrl":"10.1016/j.mcpsp.2026.100550","url":null,"abstract":"<div><div>Systemic gentamicin vestibulotoxicity is usually bilateral; unilateral involvement is exceptional and may be clinically subtle. We report a 79-year-old man with three weeks of constant gait instability, worse during walking and body turns, after intramuscular gentamicin 80 mg every 12 h for 10 days for a urinary tract infection. He had no true vertigo, autonomic symptoms, or visual motion sensitivity. Examination showed corrective saccades on rightward head impulse testing (HIT) and left-beating horizontal nystagmus after head-shaking and mastoid vibration. Audiometry showed previously documented mild bilateral hearing loss. Brain MRI showed chronic hypoxic–ischemic leukoencephalopathy, but neurological assessment found no central cause. Dynamic posturography demonstrated a vestibular dysfunction pattern, and videonystagmography confirmed right vestibular areflexia on ice-water caloric testing. Vestibular Evoked Myogenic Potentials (VEMPs) were preserved bilaterally, suggesting relative otolith sparing. Vestibular rehabilitation led to substantial improvement over 12 months, with mild residual unsteadiness during rapid head movements. This case illustrates that systemic gentamicin may produce unilateral canal-predominant vestibular loss and supports targeted vestibular assessment when new imbalance appears after treatment.</div></div>","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":"9 3","pages":"Article 100550"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Índice de inmunidad-inflamación sistémica como biomarcador en pacientes con psoriasis y artritis psoriásica 作为银屑病和银屑病关节炎患者生物标志物的全身免疫炎症指数

Medicina Clinica Practica Pub Date : 2026-07-01 Epub Date: 2026-07-17 DOI: 10.1016/j.mcpsp.2026.100551

Gabriela Fernanda González-Véliz, Elizabeth Pérez-Cruz, Lizbeth Teresa Becerril-Mendoza

{"title":"Índice de inmunidad-inflamación sistémica como biomarcador en pacientes con psoriasis y artritis psoriásica","authors":"Gabriela Fernanda González-Véliz, Elizabeth Pérez-Cruz, Lizbeth Teresa Becerril-Mendoza","doi":"10.1016/j.mcpsp.2026.100551","DOIUrl":"10.1016/j.mcpsp.2026.100551","url":null,"abstract":"<div><h3>Introduction</h3><div>Psoriasis is an inflammatory disease that can be accompanied by psoriatic arthritis (PsA). Identifying useful and accessible biomarkers for estimating the inflammatory response is vital for timely diagnosis and treatment.</div></div><div><h3>Objectives</h3><div>To evaluate the systemic inflammation-immunity index (SII) and its association with disease severity in subjects with psoriasis with and without PsA.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted on outpatients from the past three years. The relationship between the SII and disease severity was analyzed using PASI, DAPSA, and BSA. Pearson correlation coefficients were calculated. The predictive accuracy of the index for identifying disease severity was quantified by analyzing ROC curves.</div></div><div><h3>Results</h3><div>The study's sample population included 142 subjects, of which 53.5% were female, with an average age of 50.3 ± 12.2 years. Subjects diagnosed with PsA exhibited higher SII values compared to those without psoriasis (<em>p</em> = 0.03). The disease severity was found to be associated with subjects and PsA, who exhibited more severe cases and a higher BSA (<em>p</em> = 0.001). Higher disease activity was associated with a higher SII, with differences observed between severe, moderate, and low disease activity (<em>p</em> = 0.007). The optimal IIS cutoff value for identifying disease severity was determined to be 589.7 x 10<sup>9</sup>/L.</div></div><div><h3>Conclusions</h3><div>The SII has been associated with increased disease severity and may serve as an accessible biomarker.</div></div>","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":"9 3","pages":"Article 100551"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bacteriemia por Streptococcus mitis con infección de cable de marcapasos y espondilodiscitis: un cuadro clínico con implicaciones diagnóstico-terapéuticas 伴有起搏器电缆感染和脊柱炎的mitis链球菌血症：具有诊断和治疗意义的临床情况

Medicina Clinica Practica Pub Date : 2026-07-01 Epub Date: 2026-07-16 DOI: 10.1016/j.mcpsp.2026.100552

Vanesa Garrigasait Vilaseca, Joan Pros Núñez, Meritxell Santaló i Corcoy, Yaiza Delisau, Sara Grillo

{"title":"Bacteriemia por Streptococcus mitis con infección de cable de marcapasos y espondilodiscitis: un cuadro clínico con implicaciones diagnóstico-terapéuticas","authors":"Vanesa Garrigasait Vilaseca, Joan Pros Núñez, Meritxell Santaló i Corcoy, Yaiza Delisau, Sara Grillo","doi":"10.1016/j.mcpsp.2026.100552","DOIUrl":"10.1016/j.mcpsp.2026.100552","url":null,"abstract":"<div><div>Infections related to implantable cardiac devices are on the rise and are commonly associated with staphylococci. <em>Streptococcus mitis</em>, an oropharyngeal commensal of the viridans group, is also implicated in pacemaker lead infections and spondylodiscitis, although less frequently. We present the case of an 89-year-old woman with a VVI pacemaker who presented with fever and lower back pain. Blood cultures revealed <em>Streptococcus mitis</em> bacteriemia, and transesophageal echocardiography (TEE) showed a pacemaker lead infection, without echocardiographic evidence of valvular endocarditis. PET/CT and lumbar MRI revealed concomitant lumbar spondylodiscitis. This case demonstrates how an oropharyngeal commensal can be responsible for deep pharyngeal and cardiac device infections. We discussed the possible pathophysiology, the usefulness and limitations of diagnostic techniques and the therapeutic approach (targeted antibiotic therapy and device removal when appropriate) and reviewed the recent literature on the relationship between bacteriemia caused by this germ and involvement of cardiac and spinal devices.</div></div>","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":"9 3","pages":"Article 100552"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148523725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe cutaneous photosensitivity triggered by diclofenac 双氯芬酸引起严重皮肤光敏

Medicina Clinica Practica Pub Date : 2026-07-01 Epub Date: 2026-07-14 DOI: 10.1016/j.mcpsp.2026.100553

Pablo Matínez-Fernández, Mauricio Salas-Garza, Julio Salas-Alanis, María G. Moreno-Treviño, Raúl Rubio-Moreno, Israel Guerrero-Rodríguez, Gerardo Rivera-Silva

引用次数: 0

Emissary canal invasion and extrascleral extension in a rapidly growing choroidal malignant melanoma 快速生长的脉络膜恶性黑色素瘤的使者管侵入和巩膜外延伸

Medicina Clinica Practica Pub Date : 2026-04-01 Epub Date: 2026-02-27 DOI: 10.1016/j.mcpsp.2026.100536

Luca Ventura , Nadia Gabriele , Veronica Forte , Roberto Taddei , Immacolata M. Greco

引用次数: 0

Miositis necrosante autoinmune asociada al uso de atorvastatina: reporte de un caso y revisión de la literatura 与阿托伐他汀有关的自身免疫性坏死性肌炎：病例报告和文献综述

Medicina Clinica Practica Pub Date : 2026-04-01 Epub Date: 2026-01-26 DOI: 10.1016/j.mcpsp.2026.100534

Luis Ángel Rodríguez-Chávez, Melissa Ysabel Romero-Díaz, Christian Alberto Vargas Machuca-Carranza, José Guillermo Cabanillas-López

{"title":"Miositis necrosante autoinmune asociada al uso de atorvastatina: reporte de un caso y revisión de la literatura","authors":"Luis Ángel Rodríguez-Chávez, Melissa Ysabel Romero-Díaz, Christian Alberto Vargas Machuca-Carranza, José Guillermo Cabanillas-López","doi":"10.1016/j.mcpsp.2026.100534","DOIUrl":"10.1016/j.mcpsp.2026.100534","url":null,"abstract":"<div><div>Statin-associated autoimmune necrotizing myositis (ANM) is a rare entity characterized by progressive proximal muscle weakness, marked and persistent elevation of creatine phosphokinase, and the presence of anti-HMGCR autoantibodies. Unlike toxic statin-induced myopathy, ANM persists even after discontinuation of the drug due to an autoimmune response directed against the HMGCR enzyme. We report the case of a 75-year-old man on long-term atorvastatin therapy who developed severe muscle weakness, dysphagia, and respiratory involvement, initially suspected to be Guillain–Barré syndrome. The autoimmune profile revealed positive anti-HMGCR antibodies, confirming the diagnosis. Treatment included discontinuation of atorvastatin, glucocorticoids, azathioprine, and intravenous immunoglobulin, with partial improvement. This case highlights the importance of timely recognition of ANM to prevent severe complications and to guide early immunosuppressive therapy that may improve functional prognosis.</div></div>","PeriodicalId":36921,"journal":{"name":"Medicina Clinica Practica","volume":"9 2","pages":"Article 100534"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146081065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cetoacidosis euglucémica por empagliflozina: Reporte de un caso 埃帕格列氟嗪引起的euglucemic酮症酸中毒：1例报告

Medicina Clinica Practica Pub Date : 2026-04-01 Epub Date: 2026-03-04 DOI: 10.1016/j.mcpsp.2026.100535

Jose Guillermo Cabanillas-López, Luis Ángel Rodriguez-Chávez, Melissa Ysabel Romero-Diaz, Christian Alberto Vargas-Machuca Carranza

引用次数: 0

Odinofagia en un paciente joven 年轻患者的食道

Medicina Clinica Practica Pub Date : 2026-04-01 Epub Date: 2026-04-16 DOI: 10.1016/j.mcpsp.2026.100540

Carolina Broco Fernández , Alia Martín Izquierdo , María Inmaculada Matanza Rodríguez , Santiago Vivas Alegre

引用次数: 0