The outcome of complete coronary artery surgical revascularization on left ventricular function

Q4 Medicine

Medicina Clinica Practica Pub Date : 2025-07-28 DOI:10.1016/j.mcpsp.2025.100515

Zaid Mohammed Abdulwahhab Al-Noori , Laith Saleh Al-Kaaby , Heba Khaled Hatem

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Abstract

Coronary artery disease (CAD) is the leading cause of myocardial ischemia, contributing significantly to global cardiovascular mortality. Coronary artery bypass grafting (CABG) remains a cornerstone in the management of multivessel CAD.

Our objective was to evaluate the effects of complete coronary artery surgical revascularization on left ventricular function in patients with ischemic heart disease.

This prospective cross-sectional study was conducted at the Iraqi Center for Cardiac Diseases, Baghdad, from July to December 2019. Fifty patients who underwent CABG were included. Preoperative, early postoperative (2 weeks), and late postoperative (1 year) echocardiographic evaluations were performed. Echocardiographic data were obtained using the biplane modified Simpson’s method. Variables analyzed included left ventricular ejection fraction (LVEF), left ventricular internal diameters, and wall thicknesses.

No significant changes in LVEF or ventricular dimensions were observed within two weeks post-surgery. However, at one-year follow-up, patients with preoperative EF < 50% (n = 15) demonstrated a 10% increase in LVEF. Mild changes in left atrial diameter, septal wall thickness, and ventricular dimensions were also observed.

In conclusion, Patients with impaired preoperative systolic function showed significant improvement in LVEF following complete surgical revascularization. The absence of preoperative myocardial viability assessment and incomplete adherence to guideline-directed therapy were noted limitations.

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完全冠状动脉手术重建术对左心室功能的影响

冠状动脉疾病（CAD）是心肌缺血的主要原因，是全球心血管死亡的重要原因。冠状动脉旁路移植术（CABG）仍然是多血管冠心病治疗的基石。我们的目的是评估完全冠状动脉手术重建术对缺血性心脏病患者左心室功能的影响。这项前瞻性横断面研究于2019年7月至12月在巴格达的伊拉克心脏病中心进行。50例接受CABG的患者被纳入研究。术前、术后早期（2周）和术后晚期（1年）进行超声心动图评价。超声心动图数据采用双翼改进的辛普森法。分析的变量包括左心室射血分数（LVEF）、左心室内径和壁厚。术后两周内未观察到LVEF或心室尺寸的明显变化。然而，在一年的随访中，术前EF <患者；50% （n = 15）患者LVEF增加10%。左房直径、间隔壁厚度和心室尺寸也有轻微变化。总之，术前收缩功能受损的患者在完全手术血运重建术后LVEF有显著改善。缺乏术前心肌活力评估和不完全遵守指导治疗是值得注意的局限性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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