Andrology and Genital Surgery最新文献

{"title":"Right-sided scrotal varicocele in a patient with situs inversus totalis: case report","authors":"A. S. Komarov, N. Naumov, P. A. Shcheplev, Ya. A. Stoletov, A. V. Konyshev, D. S. Bazunov, S. A. Bunak, K. V. Gagai, M. Faniev, S. Suleymanov","doi":"10.17650/2070-9781-2023-24-1-157-161","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-1-157-161","url":null,"abstract":"Isolated varicocele on the right is a fairly rare disease, often associated with neoplastic processes affecting the spermatic vein system. According to new data, there is no clear relationship between varicocele on the right and neoplasms. Thus, the etiology isjustifiably related to other conditions. Mirror transposition of internal organsis one of them. Situs inversus totalis (SIT) is a rare autosomal recessive congenital anomaly with an incidence of 1 in 10,000 newborns. The etiology of right varicocele in SIT, given the structure of the right spermatic vein that flows into the renal, with the exclusion of other causes, can be considered similar to left varicocele in normal men, including venous valve insufficiency and venous pressure difference. Indications for surgery and the choice of surgical technique also do not differ. The fact of the rarity of published materials on the treatment of varicocele on the right side against the background of SIT prompted us to share this clinical case. ","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"249 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121923821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erectile function evaluation in patients after urethroplasty: systematic review and meta-analysis","authors":"D. Chinenov, E. Shpot, H. M. Ismailov, A. Proskura, Y. Chernov, L. Rapoport, D. Korolev, A. Gerasimov","doi":"10.17650/2070-9781-2023-24-1-100-114","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-1-100-114","url":null,"abstract":"Background. The success of surgical treatment of urethral strictures is often assessed in terms of the quality of urination and the patency of the urethral lumen. Despite the fact that this assessment is carried out according to the above parameters, it seems important to take into account such a possible complication as erectile dysfunction, which can significantly impair the patient’s quality of life. This is the difference in the perception of the success of the surgical intervention by the clinician and the patient.Aim. To determine the relationship between urethroplasty and the likelihood of erectile dysfunction in the postoperative period according to world literature.Materials and methods. The PubMed database was analyzed using the keywords: anterior urethroplasty, posterior urethroplasty, urethroplasty, sexual dysfunction, erectile dysfunction. All articles were reviewed by two independent authors for inclusion based on predetermined criteria. Among the included scientific papers are randomized controlled trials, systematic reviews.Results. Sixteen scientific papers with a total of 1476 patients were included in the final study. The decrease in erectile function after surgery in this meta-analysis is 3 %. The main factors influencing postoperative parameters were age and erectile function at the time of surgery.Conclusion. Most studies state that urethroplasty does not imply a significant impact on erectile function, however, they acknowledge that the occurrence of this complication affects the assessment of treatment outcomes among patients and the further impact on their quality of life, regardless of postoperative urinary function. ","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125204025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic and semen examination of patients with 46,XX testicular disorder of sex development","authors":"M. Shtaut, T. Sorokina, L. Kurilo, M. Andreeva, N. Oparina, A. Polyakov, N. V. Shilova, V. Chernykh","doi":"10.17650/2070-9781-2023-24-1-115-129","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-1-115-129","url":null,"abstract":"Background. 46,XX male syndrome (XX sex reversal) or 46,ХХ testicular disorder of sex development (DSD) – a genetic disorder that characterized by primary hypogonadism and male infertility because of severe spermatogenesis defects. 46,XX testicular DSD is resulted from unbalanced microstructural sex chromosome abnormalities, mostly X-Y translocations involving SRY gene. Genetic heterogeneity and phenotypic variability, particularly the effect of the genotype on semen parameters in XX sex reversed patients are not sufficiently studied.Aim. Genetic and semen examination in patients with 46,ХХ testicular DSD.Materials and methods. 32 patients with 46,XX testicular DSD and 2 men with mosaicism 46,XX/46,XY were examined. Cytogenetics, molecular genetics and spermatology examination (standard semen analysis and quantitative karyological analysis of immature germ cells) were performed.Results. The presence of the SRY gene was detected in 23 (82.1 %) of 28 patients who underwent a molecular genetic study, and 5 patientswere SRY-negative. Azoospermia and severe oligozoospermiawere diagnosed in 24 (75 %) and 8 (25 %) patients, respectively. Quantitative karyological analysis of immature germ cells allowed to reveal cryptozoospermia in 3 patients with initially diagnosed azoospermia (according to a standard semen analysis). Severe oligozoospermia and cryptozoospermia were mentioned both in some of SRY-positive and SRY-negative patients.Conclusion. 46,XX testicular DSD is characterized by severe degree of spermatogenesis defects (azoospermia and extremely severe oligozoospermia). Small number of germ cells detected in ejaculate in some patients with 46,XX testicular DSD, including SRY-negative individuals, indicates partial preservation ofspermatogenesisin the absence of Y chromosome genes. ","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"368 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124614202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving the choice of surgical tactics in geriatric patients with benign prostatic hyperplasia","authors":"I. G. Leshchenko, O. Bratchikov, A. I. Akimov, Yu. A. Zhilyaeva","doi":"10.17650/2070-9781-2023-24-1-138-149","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-1-138-149","url":null,"abstract":"Background. The analysis of modern scientific literature indicates that if the list of indications for elective surgery in geriatric patients with benign prostatic hyperplasia (BPH) meets the requirements of urological practice, then the contraindications for this operation clearly do not correspond to them.Aim. Based on the current list of contraindications to elective surgery in geriatric patients with BPH, to develop rational surgical tactics aimed at reducing the frequency and severity of postoperative complications and deaths.Materials and methods. Examination and treatment of 295 geriatric patients with stage 2 BPH (main group A) who underwent planned transurethral resection of the prostate or transpusical adenomectomy in the period from 2007 to 2015 at the Samara Regional Clinical Hospital of War Veterans (the clinical base of the First Research Institute of Clinical Gerontology and Rehabilitation of War Veterans of the Medical University “Reaviz”). During this period, 116 geriatric patients with stage 2 BPH (main group B) using the author’s list of contraindications, elective surgery was contraindicated. They underwent conservative treatment. The control group consisted of 344 geriatric patients with stage 2 BPH who underwent elective transurethral resection of the prostate or transpusical adenomectomy in the same Hospital from 2000 to 2006, taking into account the contraindications to these operations that existed at that time. The age of patients in all groups was from 60 to 89 years.Results. The use of this list made it possible to establish among 116 patients (main group B) excretory absolute contraindications to surgery were performed in 48.3 % of patients, relative present contraindications of the second – in 33.6 %, temporary contraindications of rendering – in 13.8 %, a special contraindication to transurethral resection of the prostate – in 1.7 %, special contraindications to transvesical adenomectomy – in 2.6 %, which contributed to the prevention of possible postoperative complications and deaths among them.Conclusion. The clinical expediency of using the author’s approach to the choice of surgical tactics, taking into account contraindications to elective surgery in geriatric patients of the main group A, compared with patients of the control group, consisted in reducing of postoperative complications and deaths and increasing of good immediate treatment results among them. ","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125830020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age dynamics of the morphological structure of the cavernous arteries in healthy men according to complex morphometric analysis","authors":"A. N. Strelkov, A. Astrakhantsev, S. Snegur","doi":"10.17650/2070-9781-2023-24-1-130-137","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-1-130-137","url":null,"abstract":"Background. Erectile dysfunction is associated with systemic vascular diseases and, to a greater extent, with age, while there is insufficient data in the literature on the morphological state of the cavernous arteries (CA) in men of different ages in normal.Aim. A detailed morphometric assessment of the CA of men of various ages in the absence of signs of atherosclerosis and hypertension.Materials and methods. The material was transverse fragments of cavernous bodies with paired CA obtained during autopsy (58 observations, a total of 116 CA were examined). Hematoxylin and eosin, fuchsylin and picrofuxin, and Mallory staining were used. Detailed morphometric analysis was carried out according to the original method by measuring the perimeter and then calculating the area of the corresponding component of the vascular wall.Results. In the studied age range from 17 to 74 years, there was an increase in the total area of the CA from 0.76 mm2 in the age period of 17–21 years to 0.99 mm2 in the period of 36–60 years and a decrease to 0.43 mm2 at the age of 61–74 years. А similar increase in absolute indicators of the area of the lumen with a decrease in old age was revealed. The absolute area of intimacy and media, increasing by the age of 36–60 years, also significantly decreases in the age range of 61–74 years. At the same time, the relative area of intima to the vessel lumen has insignificant fluctuations, remaining a stable value in all age groups. The specific area of intima relative to the entire area of the vessel as a whole has a stable indicator, increasing in old age. The Kernogan Index tends to decrease throughout the studied age range from 33 to 26 %, which indicates the preservation of the spacecraft throughput in all the studied groups, including the elderly. This is also evidenced by the dynamics of the ratio of the diameter of the CA lumen to the thickness of the vessel wall, including intima and media, reaching maximum values of 4.15 by the period of 36–60 years, remaining at a high level of 3.53 and in the oldest age group. At the same time, the specific share of media significantly decreases in all groups of the studied age range of 17–74 years from 62.1 to 50.5 %. The ratio of the maximum lumen area of the vessel to the minimum as an indicator of the potential possibility of increasing the lumen of the spacecraft turned out to be maximum atthe ages of 17–21 years and 22–35 years,significantly decreasing in older age groupsfrom 176 to 130 %.Conclusion. Age-related remodeling of the spacecraft consistsin fairly stable morphometric parameters of the spacecraft in the age range from 17–21 years to a period of 36–60 years with a decrease at an older age, when a decrease in the absolute area of the lumen and the entire spacecraft isrevealed. A significant progressive decrease in the specific proportion of media and an increase in the proportion of intima in the structure of the vessel wall are shown. At the same time, up to the age of 36","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122126020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and economic analysis of different surgical approaches for benign prostatic hyperplasia (literature review)","authors":"S. Volkov, O. Grigoryan, N. Mokrysheva, E. Andreeva, R. K. Mikheev, V. Tereshchenko, K. Kolontarev","doi":"10.17650/2070-9781-2023-24-1-84-89","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-1-84-89","url":null,"abstract":"Wide spectrum of surgical techniques and approaches is used nowadays for treatment of benign prostatic hyperplasia (BPH). Every method is chosen individually for every patient depending on clinical and anamnestic data, ratio risk/ratio and surgeon’s professional skills. Debits for treatment of benign prostatic hyperplasia have a trend for annual increasement in countries with demographic aging. Present article is dedicated to overview of financial and economic aspects of main surgical techniques: open simple prostatectomy, transurethral resection and laser enucleation. ","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121281646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of a questionnaire on pelvic organ function for neurological patients in Russia","authors":"E. Korshunova, D. Yusupova, A. Zimin, T. M. Pyatnitskaya, A. Zaitsev, K. A. Yatsko, N. V. Polekhina, N. Belova, M. Korshunov, D. Korshunov, S. Darenkov, N. Suponeva, R. Sakakibara","doi":"10.17650/2070-9781-2023-24-1-90-99","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-1-90-99","url":null,"abstract":"Background. Dysfunction of the bladder and intestinal tract, as well as sexual disorders, can be caused by pathologies of the pelvic organs themselves or changes in the control of these organs by the nervous system. Modern questionnaires are organ-specific and are intended for specific neurological disorders. Questionnaire on pelvic organ function is a valuable instrument for evaluation of complaints from neurological patients, therefore there is a necessity of creating an official adapted Russian version.Aim. Creation of a Russian-language version of the pelvic organ function questionnaire and its validation on a cohort of patients with neurological diseases.Materials and methods. Following international standards, validation of the questionnaire included linguistic and cultural adaptation and assessment of its psychometric properties. Approval of the Russian-language questionnaire version was obtained directly from the developer, Ryuji Sakakibara. The questionnaire was tested twice – before and after treatment. There were 48 patients over 18 years old (18 with Parkinson’s disease, 15 with multiple sclerosis, and 15 post-stroke).Results. The Median (IQR) age of patients was 56.5 (42–70.5) years. A Russian-language version of the questionnaire was developed during linguistic and cultural adaptation. This version of the questionnaire is posted in the text of this publication. It is also available on the website of the validation group of the international scales and questionnaires of the Research Center of Neurology. At the 2nd stage of validation, it was shown that the mean score in the sample was 2.03 ± 0.52 per question upon admission to the hospital and decreased significantly to 1.91 ± 0.51 per question on discharge (Wilcoxon test, p ˂ 0.0001). It confirms the questionnaire’s high sensitivity to changes in the clinical picture. Cronbach’s alpha coefficient was 0.82 (p ˂ 0.001).It indicates the high level of internal consistency of the questionnaire. Significant Spearman’s coefficients prove criterion validity of the studied questionnaire compared to the established questionnaires.Conclusion. This Russian-language version of the pelvic organ function questionnaire is a useful assessment tool for patients’ complaints and disease dynamics. This work is valuable as an example of adapting a foreign scale or questionnaire to the local health care system. ","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126652709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erectile dysfunction in patients after kidney transplantation and nephrectomy in living donors: literature review","authors":"Z. Kadyrov, A. Y. Odilov, F. S. Sadulloev, M. Faniev, S. Suleymanov, E. I. Rossoshanskaya","doi":"10.17650/2070-9781-2023-24-1-57-65","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-1-57-65","url":null,"abstract":"Аnalysis of the world literature shows that sexual dysfunction is a common problem in patients with chronic renal failure and after kidney transplantation in both men and women, which requires proper attention of specialists. The etiology of sexual dysfunction remains multifactorial and is associated with the level of azotemia, comorbidities, age, anemia, hormonal disorders, autonomic neuropathy, vascular diseases, hyperparathyroidism, hyperprolactinemia, drug side effects, and psychosocial factors. Sexual dysfunctions have a serious impact on the quality of social and family life of patients. On the one hand, in most cases, there is an increase in life expectancy and an improvement in the quality of life of patients after kidney transplantation. Due to the normalization of hormonal disorders, it improves sexual health (libido), overall health and fertility. On the other hand, after kidney transplantation, the prevalence of sexual dysfunction still remains at 46 % in both men and women. After kidney transplantation, erectile function in many patients improves and some recover. However, not all authors note an improvement in sexual dysfunction after kidney transplantation and leave the problem open. Conservative therapy with oral forms of drugs is most advantageous compared to cavernous injections or surgical treatment, if it does not affect the function of the graft. Sexual disorders after kidney transplantation remain a multifactorial disorder, and methods of their correction, especially in young patients, remain an urgent problem and require further study. ","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133957786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimally invasive techniques of urethral stricture treatment and their use in patients of pediatric age (literature review)","authors":"E. A. Ladygina, N. Demin, V. Nikolayev, M. Faniev, S. Suleymanov","doi":"10.17650/2070-9781-2023-24-1-66-74","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-1-66-74","url":null,"abstract":"Urethralstricture remains one of the most discussed problemsin pediatric urology. Despite a significant number of articles and the existence of a wide variety of methods for treating urethral strictures and their modifications, every new generation of urologists encounters this problem.Treatment of urethralstricture often takes a long time and requires multiple surgical interventions. Treatment techniques continuously improve, therefore it is appropriate to regularly summarize new data. Such methods as bougienage, balloon dilation and urethralstenting are still being used, although as early asin the beginning of the 19th century the first types of such modern method as optical internal urethrotomy were developed. In relation to optical internal urethrotomy, discussions on indications, techniques, duration of catheterization, necessity of combination with intermittent catheterization, use of hormonal drugs continue. The question of the number of attempts to perform urethrotomy also remains controversial.In this review, we tried to clarify the problem of use of minimally invasive techniques for urethral stricture treatment in children in the context of current scientific data and historical aspects. ","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132939598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of neuromodulation techniques in children with bladder and bowel dysfunction","authors":"Z. Z. Sottayeva","doi":"10.17650/2070-9781-2023-24-1-75-83","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-1-75-83","url":null,"abstract":"One of the urgent problems in modern pediatric urology is a significant range of diseases associated with various dysfunctions of the bladder and rectum, which leads to the search for new effective methods that restore bladder function. From 20 to 40 % of cases of pelvic organ dysfunction in children are resistant to conservative treatment, which suggests that the use of a modern method of physiotherapy – electrical nerve stimulation – can be a treatment method when other methods do not have the desired effect. ","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"113 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123303270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}