Andrology and Genital Surgery最新文献

{"title":"Detection of Ureaplasma species in males with reproductive problems in marriage","authors":"R. T. Savzikhanov, A. A. Muskhadzhiev, M. Katibov","doi":"10.17650/2070-9781-2023-24-2-95-102","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-2-95-102","url":null,"abstract":"The article provides information on the impact of Ureaplasma infection on the reproductive function of men. It was found that the prevalence of the microorganism in men with reproductive pathology was 55 %. The presence of ureaplasmas in clinically healthy men, the relationship with the presence of inflammatory diseases of the urinary system, male infertility and adverse pregnancy outcomes were determined. It has been established that ureaplasmas make the greatest contribution to the development of miscarriage and adverse pregnancy outcomes.","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125013603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunohistochemical basing of the pathogenesis equality of varicose vein transformation in varicocele and varicose veins of the lower extremities","authors":"L. Severgina, V. V. Studennikova, L. Rapoport, I. Korovin, D. Korolev","doi":"10.17650/2070-9781-2023-24-2-77-84","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-2-77-84","url":null,"abstract":"Background. Varicocele as well as varicose veins of the lower extremities are quite widespread. To date, the mechanisms of variceal transformation remain not completely clear.Aim. To study the immunohistochemical profile in order to substantiate the common pathogenesis of varicose veins transformation in varicocele and varicose veins of the lower limbs; to confirm the key role of undifferentiated connective tissue dysplasia syndrome in the development of these diseases.Materials and methods. Vein wall fragments from 24 male patients aged 6–35 years old divided into the corresponding groups: group 1–12 patients with varicocele, group 2–12 patients with varicose veins of the lower limbs. Control group – 5 practically healthy men (age 16–32 years). Immunohistochemical study was performed with monoclonal antibodies to collagen types III, IV, α-SMA, fibronectin, laminin, MMP-2 and MMP-9, TGF-β1.Results and discussion. Histological and immunohistochemical studies of vein wall biopsy specimens in both groups revealed similar morphological changes, different from the control group. When assessing the expression level of α-SMA in both study groups, there was marked expression in the bundles of hypertrophic smooth muscle cells (in the zone of wall thickening where fibrosis was minimal) and weak expression in the bundles of smooth muscle cells “enmeshed” in connective tissue sleeves. Collagen type III showed weak expression in the subintimal zone and between the bundles of superficially located smooth muscle cells in both study groups. Expression of type IV collagen was detected in the areas of wall thickening and hypertrophy of smooth muscle cells. In both groups there was a pronounced expression of fibronectin in the most altered sections of the vein walls, especially in the middle layer, around the bundles of smooth muscle cells. There was marked expression of MMP-2 in all layers of the wall, and overexpression of MMP-9 in the areas of wall thinning (in the subintimal zone and muscular layer). TGF-β1 overexpression was also detected in vein biopsy specimens from both groups, predominantly in areas of thinning and pronounced intermuscular fibrosis.Conclusion. Taking into account the similarity of immunohistochemical manifestations in the vein walls in varicocele and varicose veins of the lower limbs we can speak about the common morphogenetic mechanisms of their remodeling. Thus, we consider it possible to combine various forms of varicosity into a single disease – varicose vein disease.","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115872593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Historical and modern aspects of vascular andrology","authors":"A. Kapto","doi":"10.17650/2070-9781-2023-24-2-58-65","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-2-58-65","url":null,"abstract":"Vascular andrology, or angioandrology, was formed on the principle of an interdisciplinary approach in medicine. The object of study were pelvic varicose veins, arteriovenous conflicts, chronic pelvic pain syndrome, erectile dysfunction, prostatic hyperplasia and lower urinary tract symptoms. New approaches developed within this scientific and clinical direction have significantly improved the results of treatment of urological and andrological patients.","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114728893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical significance of varicocelectomy: literature review","authors":"Yu. V. Olefir, E. A. Efremov, M. A. Rodionov, A. R. Zhivulko, D. M. Popov, D. M. Monakov, M. Faniev","doi":"10.17650/2070-9781-2023-24-2-49-57","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-2-49-57","url":null,"abstract":"Surgical treatment of clinically significant varicocele in infertile men with pathospermia is a common practice. However, the question of the role of this disease in the pathogenesis of such conditions as hypogonadism and orchalgia, as well as the role of varicocelectomy in eliminating pain symptoms in the scrotum and increasing testosterone levels, has remained ambiguous for a long time. The expediency of surgical treatment of varicocele in patients with azoospermia also remains a subject of discussion.","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122132450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is oxytocin an undeservedly forgotten hormone in men?","authors":"I. Tyuzikov, E. A. Grekov, A. Smirnov","doi":"10.17650/2070-9781-2023-24-2-66-76","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-2-66-76","url":null,"abstract":"Oxytocin is one of the most ancient mammalian hormones in terms of phylogeny. Over the more than 100-year history of his scientific study, views on the biological functions of oxytocin in humans have undergone a significant and even revolutionary changes. For a long time, this neurohypophysis hormone, which is formed in the hypothalamus and is only deposited in it (central synthesis), was associated exclusively with female reproduction in the aspect of labor, breastfeeding and maternal behavior. However, over the past decades, a unique and extensive scientific base has been created confirming the universal nature of the effects of oxytocin in both sexes, which is predetermined by the presence of additional peripheral sites of oxytocin secretion in men and women, as well as an extensive receptor apparatus in many cells and tissues, which together allows oxytocin to function both endocrine central and auto- and paracrine local signaling pathways. This fact convincingly proves that oxytocin has a much wider range of physiological effects in the body of both sexes, and the results of modern research allow us to consider it as a central neuropeptide and a peripheral multifunctional hormone of great biological and social significance for humans.The review article briefly discusses the endocrinology of oxytocin and in more detail its physiological effects in men, including its role in social and sexual behavior, erectile function, protection from stress, reproduction, metabolism, prostate gland. ","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128940623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The negative impact of phthalates on male reproductive system and fertility","authors":"A. Sedova, V. B. Сhernykh","doi":"10.17650/2070-9781-2023-24-2-19-30","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-2-19-30","url":null,"abstract":"The paper overviews the negative impact of phthalates on the male reproductive system, spermatogenesis, semen parameters and male fertility. The analysis of the literature revealed few studies devoted to the study of the effect of phthalates on reproductive health, gametogenesis and fertility in humans and laboratory models (rats, mice). Although epidemiological studies on the effect of phthalates on the male reproductive health are not big, some toxicological studies show that some phthalates are potential reprotoxicants.","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127970813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New possibilities of cell and shock wave therapy in erectile function recovery in patients after radical prostatectomy: a review","authors":"M. Epifanova, A. Kostin, E. Gameeva, A. Gritskevich, S. Artemenko, A. Epifanov","doi":"10.17650/2070-9781-2023-24-2-41-48","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-2-41-48","url":null,"abstract":"For the first time in 2021, prostate cancer took 1st place among other oncological diseases in Western countries. Radical prostatectomy is still the method of choice among the prostate cancer radical therapy. An important unresolved problem remains the rehabilitation, since the overwhelming number of patients in the postoperative period develop sexual dysfunction, urination disorders, which significantly reduces the quality of life. Thus, this condition actualizes the search and development of new approaches to the therapy of erectile function after radical prostatectomy. This literature review presents the results of a literary search of Russian and international databases on the erectile function recovery after radical prostatectomy using platelet rich plasma and extracorporeal shock wave therapy.","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130136698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organizational issues of surgical treatment of urological and andrological patients in the conditions of COVID-19: literature review","authors":"Z. Kadyrov, M. Faniev, S. Suleymanov, V. Z. Kadyrova, G. M. Mushukiya, K. V. Gagai","doi":"10.17650/2070-9781-2023-24-2-31-40","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-2-31-40","url":null,"abstract":"The COVID-19 pandemic has made adjustments to the management of patients in many medical areas, including urological ones, and the transition of the priorities of the healthcare system to the treatment of patients with a new coronavirus infection has led to a decrease in the quality and intensity of care for patients with other pathologies.","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115271578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Don’t jump to conclusion – priapism in acute spinal cord injury: a case presentation","authors":"M. Yusof, O. Afiq, M. Khairul‐Asri","doi":"10.17650/2070-9781-2023-24-1-162-166","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-1-162-166","url":null,"abstract":"Priapism is an uncommon urology emergency. However, if detected late and not classified correctly and treatment not appropriately given can cause necrosis and fibrosis of penis. This will lead to permanent erectile dysfunction and can be devastating to patient. Literature of Spinal Cord Injury with priapism is rare and not many reported. We have a case of young gentleman with priapism secondary to spinal cord injury. It was detected early and treated promptly and patient had good outcome with no evidence of permanent erectile dysfunction. ","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"24 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133569211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between seminal plasma cytokine levels and asthenozoospermia in infertile men","authors":"A. Muradian, S. Gamidov, A. U. Popova, R. I. Ovchinnikov, T. Shatylko","doi":"10.17650/2070-9781-2023-24-1-150-156","DOIUrl":"https://doi.org/10.17650/2070-9781-2023-24-1-150-156","url":null,"abstract":"Background. Violation of male fertility can have various causes, one of which is a decrease in sperm motility. In the pathogenesis of asthenozoospermia, some bioactive substances, in particular cytokines, may be involved.Aim. To estimate the number of the most studied cytokines to date in the ejaculate of infertile men with normozoospermia and patients with asthenozoospermia.Materials and methods. We examined 38 infertile patients with normozoospermia and 10 men with asthenozoospermia, comparable in age. All participants in the study were performed a spermogram and an analysis to determine the amount of the cytokines in seminal plasma, such as interleukins 1β, 2, 4–8, 10, 12, 13, 17, G-CSF, GM-CSF, interferon γ, MCP-1, MIP-1β and tumor necrosis factor α. Then, using nonparametric statistics, the relationship between the level of the above cytokines and the presence of asthenozoospermia was analyzed.Results. As a result, we were able to find out that there is a relationship between the concentration of interleukin 6, interleukin 8 and MIP-1β and sperm motility.Conclusion. Further research is needed to assess whether these bioactive inflammatory mediators have potential relevance for use as targets in the treatment of male infertility. ","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131986789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}