Andrology and Genital Surgery最新文献

{"title":"Correction of chronic prostatitis by extracorporeal shock wave therapy","authors":"M. Epifanova, А. Kostin, E. Gameeva, S. Artemenko, А. Epifanov","doi":"10.17650/1726-9784-2022-23-1-53-59","DOIUrl":"https://doi.org/10.17650/1726-9784-2022-23-1-53-59","url":null,"abstract":"Introduction. This article presents the results of treatment of patients with chronic prostatitis (CP) type II, IIIA and IIIB by extracorporeal shock wave therapy (ESWT).The study objective was to evaluate the effectiveness of ESWT in the treatment of CP.Materials and methods. The research included 43 patients with CP. The patient’s age was 38.8 (27–65). The mean CP duration was 13.5 (3–24) months. 43 patients were assigned into 3 groups based on transrectal ultrasound (TRUS) examination. Group 1 had fibrotic changes in the prostate (n = 21). Group 2 had prostate calcifications (n = 5). Group 3 had fibrotic changes and calcifications in the prostate (n = 17). Treatment included ESWT (Dornier Aries) twice per week during 6 weeks. Each ESWT-session was comprised 2000–3500 pulses (0.05–0.062 mJ/mm2) and 8–6 Hz of frequency. All men were evaluated on 0 and 60 days of the study using NIH-CPSI (National Institutes Health Chronic Prostatitis Symptom Index), IPSS (International Prostate Symptom Score), TRUS of the prostate, the culture of seminal or prostate fluid, spermogram or prostate fluid analysis, serum prostatic specific antigen for men over 50 years of age.Results. The patients over 50 years-old had total prostatic specific antigen less than 4 ng/ml. Bacterial growth was found in the culture of seminal/prostate fluid of the 26 patients. They were additionally prescribed antibiotics according to antibiogram. All patients got the treatment well. Control study pointed at lower scores of NIH-CPSI – grade decreased from 13.39 (1–34) to 5.54 (0–24) (p <0.05), IPSS decreased from 11.39 (0–34) to 4.39 (0–29) (p <0.05). Prostate volume decreased from 25.18 (12.2–58.8) cm3 to 22.78 (12–56.6) cm3 according to TRUS (p >0.05). In the group 1 in 3 cases local fibrosis were completely resolved, in 18 cases fibrotic changes decreased from 5.3 (0–13) mm to 3.24 (0–8.1) mm (p <0.05). In the second group the number and the size of calcifications decreased from 6.92 (2–21) mm to 4 (0–20) mm (p >0.05). In the group 3 calcifications were completely resolved (p <0.05), the volume of fibrosis decreased from 6.8 (3.2–15) mm to 4.5 (1–17) mm (p <0.05). Bacterial growth wasn’t found in 9 patients’ seminal/ prostate fluid, 16 patients had a decrease of the causative agent concentration on 60 day, WBC count normalized in all subjects with CP/chronic pelvic pain syndrome IIIA.Conclusion. ESWT is an effective and non-invasive method of treatment of CP type II, IIIA and IIIB. The proposed treatment to relieve pain syndrome, inflammation, to promote lysis of fibrosis zone and calcinates, improves the draining function of prostate, contributing to accelerated elimination of microflora.","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115893540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant spermatic cord lipoma: case report","authors":"A. Muradian, S. Gamidov, T. Shatylko, O. Ahmedov","doi":"10.17650/1726-9784-2022-23-1-89-93","DOIUrl":"https://doi.org/10.17650/1726-9784-2022-23-1-89-93","url":null,"abstract":"Benign extratestinal lesions, including spermatic cord lipomas, are often incidental findings on palpation of the scrotum. There are frequent cases of detection of lipomas both when performing hernioplasty of inguinal hernias, and during other surgical interventions in the inguinal canal or in the scrotum. Lipomas of the spermatic cord can accompany the hernia of the inguinal canal, and in some cases, and proceed independently.Some authors have described cases of erroneous diagnosis of huge extratesticular lipomas as inguinal hernias, while suggesting that the lipoma of the spermatic cord be recognized as an important clinical unit necessary in conducting a thorough urological differential diagnosis in order to avoid unnecessary hernioplasty. It is not always easy to determine the correct tactical and technical techniques, their sequence, adequacy for each specific case. This is due to the limited time for decision-making and the high emotional burden that the doctor bears when examining and deciding treatment tactics at the time of surgery. This fact prompted us to share our clinical observations and suggest step-by-step surgical tactics that we use.","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121895375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of various factors on ejaculate fertility in vitro","authors":"V. Evdokimov, N. K. Isaev, V. B. Turovetskiy","doi":"10.17650/1726-9784-2022-23-1-45-52","DOIUrl":"https://doi.org/10.17650/1726-9784-2022-23-1-45-52","url":null,"abstract":"Introduction. Current demographic situation in Russia is characterized by decreasing birth rate. According to the World Health Organization, percentage of child-free marriages in various countries is 10–15 %. In Russia, the National Medical Research Center for Obstetrics, Gynecology, and Perinatology named after Academician V.I. Kulakov states that this number is 17 %. More than 4 million men suffer from infertility of various types. In recent years, pathologies of male reproductive function have achieved medical and social significance due to progressively decreasing sperm fertility. Fertility disorders are considered multi-factor conditions caused by internal and external factors and leading to pathological changes in sex organs. Correction of pathologies of male fertility does not always lead to positive results. Therefore, it is important to develop and study effective pharmaceuticals affecting the main fertility parameters.The study objective is to investigate the effect of various biological pharmaceuticals, physical and chemical factors on parameters of ejaculate fertility in vitro.Materials and methods. Experiments with a protein-peptide complex (PPC), methylene blue, and hydrogen peroxide were performed on human semen. After semen dilution, the sample was studied under the microscope and sperm motility and other ejaculate parameters were evaluated per the 5th edition WHO standard. Experiments were performed at 20–22 ºС. Statistical data analysis was performed using the Student’s t-test. Differences were considered statistically significant at р <0.05.Results. The results show increased motility in the fraction of active motile sperm in first 30 minutes after incubation with methylene blue. In case of initial asthenospermia, active motility increased by 72 %, in case of normospermia by 89 %. After 2 hours, all motility fractions were at the baseline level.The experiments also showed significant changes in sperm motility in the presence of PPC preparation in the ejaculate: increase in sperm motility was observed beginning at 30-minute mark and this level persisted through 3 hours of observation. A more pronounced change, by 60 %, was observed in the active motile sperm; total motility increased by up to 30 %. After 24 hours, sperm motility remained close to the baseline level, the number of normal sperm forms and live cells did not change. Dependence of the motility change on the preparation concentration should be noted: the highest increase was observed at PPC concentration with total protein level of 10–12 mg/mL. Higher concentrations did not have a positive effect on sperm motility. In experiments with low hydrogen peroxide concentration, a positive effect on sperm motility was observed.Conclusions. Sperm motility is supported by glycolysis energy, and one of the glycolysis enzymes glyceraldehyde 3-phosphate dehydrogenase is tightly bound to the fibrous layer of the flagellum, activation of metabolic pathways leading to increased enzym","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124342759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"De Castro phalloplasty in a child with partial amputation of the penis after electrical burn of the external sex organs","authors":"V. V. Rybchenok, S. Kovarsky, K. A. Struyansky, S. Blokh, L. Y. Idris","doi":"10.17650/1726-9784-2022-23-1-82-88","DOIUrl":"https://doi.org/10.17650/1726-9784-2022-23-1-82-88","url":null,"abstract":"The article describes a method of surgical formation of a neophallus in a child with burned penis and presents a literature review on treatment techniques and patient management tactics for this pathology. De Castro phalloplasty is actively used in children with aphallia and male karyotype 46,ХY, micropenis, and exstrophy–epispadias complex. Uniqueness of the presented clinical demonstration lies in the fact that it is the first time in Russia De Castro phalloplasty was performed in a child with partial amputation of the penis.","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"8 14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130081047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Rotaprost mineral-herbal complex effectiveness for improvement of functional condition of the male urogenital system","authors":"O. Zhukov, E. Bragina, V. Evdokimov, A. E. Vasiliev, M. Ulusoylu-Dumlu","doi":"10.17650/1726-9784-2022-23-1-60-75","DOIUrl":"https://doi.org/10.17650/1726-9784-2022-23-1-60-75","url":null,"abstract":"Introduction. Modern studies indicate a close relationship between the deterioration of the quality of the ejaculate and the increase in the symptoms of the lower urinary tract (LUTS) with the increase in the age of the man. Taking into account the common pathogenesis of reproductive dysfunction, LUTS and the development of possible preventive measures, we conducted an independent study.The study objective was to evaluate the effectiveness of the combined dietary supplement Rotaprost to improve the functional state of the male genitourinary system.Materials and methods. The study included 30 patients with clinical and laboratory signs of infertility and LUTS aged 23–65 years (mean age 44.91 ± 4.5). Patients were divided into two groups of 15 patients. Group 1 with chronic pelvic pain syndrome (CPPS) of IIIb category (US National Institutes of Health, 1995) with secretory type of infertility and LUTS, group 2 of 15 patients with stage 1 benign prostatic hyperplasia (BPH), pathozoospermia and LUTS. During the study, clinical and laboratory parameters were registered, NIH-CPSI, IPSS-QoL, IIEF-5, NRS questionnaires were used, spermogram data, MAR test, oxidative stress, DNA fragmentation, and electron microscopy of spermatozoa were evaluated. All patients before and after treatment underwent triplex ultrasound of the scrotum and transrectal ultrasound of the prostate. Expert-class devices E-CUBE 15 (Alpinion) were used. Patients included in the design of the study took Rotaprost capsules No. 30, 1–2 times a day for 30 days at the place with meals, drinking a small amount of water. After the course of treatment, patients were examined again.Results. The results of the study showed a more significant effect on the parameter of progressive mobility after treatment in the group with CPPS IIIb (group 1) by 23.5 % compared to the BPH group, where the total increase was 10.7 %. Also, an interesting finding was the trend towards a decrease in the number of leukocytes in the semen while taking Rotaprost in patients with CPPS IIIb (from 1.22 million/ml to 0.43 million/ml) compared with the BPH group, where changes are less significant (from 0.68 million/ml to 0.36 million/ml). Comparing the level of reactive oxygen species in the ejaculate and assessing the DNA fragmentation of spermatozoa revealed a statistically significant decrease during treatment in both groups, reducing the amount of residual urine. The drug had a significant effect on the level of pain, assessed by the NRS scale and improved the quality of life, including IPSS-QoL and NIH-CPSI data. Conclusions. Rotaprost mineral-herbal complex allows to correct moderate pathozoospermia and indicators of impaired urination in the vast majority of patients with CPPS IIIb and men with stage 1 BPH.The use of the Rotaprost mineral-herbal complex for a month leads to an improvement in the quality of life of patients with CPPS IIIb, reducing their pain by 25 %, restoring the quality of urination, and reduce t","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127068479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative karyological analysis of immature germ cells from ejaculate with normal sperm count","authors":"M. Andreeva, M. Shtaut, L. Dobrodeeva, T. Sorokina, V. Chernykh, L. Kurilo","doi":"10.17650/1726-9784-2022-23-1-37-44","DOIUrl":"https://doi.org/10.17650/1726-9784-2022-23-1-37-44","url":null,"abstract":"Introduction. The number of immature germ cells (IGCs) in ejaculate and the ratio of these cells at different stages of their differentiation can reflect meiotic progression and the state of spermatogenesis. Quantitative karyological analysis of immature germ cells from the ejaculate (QKA IGCs) makes it possible to distinguish and analyze all the stages of cell differentiation during spermatogenesis.Purpose. To analyze the spermatogenesis in men with impaired fertility and possible correlation between semen analysis and QKA IGCs parameters. Materials and methods. We analyzed 52 semen samples with normal sperm concentration, normal ejaculate volume and pH. Sperm examination according to WHO criteria and QKA IGCs from the ejaculate were performed (patent of L.F. Kurilo No. 2328736, 2007). According to the number of leukocytes, we divided two groups: a group with normal concentration of leukocytes in the ejaculate (group 1, n = 34) and a group with leukospermia (group 2, n = 18).Results. Increased IGCs index was found in 56 % of the samples in group 1 and 61 % of the samples in group 2. A positive statistically significant correlation was found between the number of spermatocytes I and sperm concentration (group 1), as well as the number of spermatocytes I and morphologically normal spermatozoa (group 2). The average number of non-divided spermatids in group 2 was statistically higher than in group 1. A negative statistically significant correlation was found between the number of non-divided spermatids and the number of morphologically normal spermatozoa, as well as the concentration of germ cells (group 2). Increased IGCs index was found in both pathozoospermia and normozoospermia.Conclusions. The QKA IGCs is an independent method for spermatogenesis evaluation and can be recommended as part of the protocol for examining men with reproductive disorders along with standard semen analysis.","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123836321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemiluminescence analysis of free radical processes in seminal plasma of men with pathospermia who have undergone COVID-19 infection","authors":"N. Kurashova, B. Dashiev, L. Grebenkina, S. Kolesnikov, L. Kolesnikova","doi":"10.17650/1726-9784-2022-23-1-30-36","DOIUrl":"https://doi.org/10.17650/1726-9784-2022-23-1-30-36","url":null,"abstract":"Introduction. In the context of the COVID-19 pandemic, it seems relevant to study the clinical features and the effect of the SARS-CoV-2 virus on the reproductive system and male fertility.The study objective was to assess the intensity of oxidative processes in the seminal plasma of men with pathozoospermia after suffering a COVID-19 infection.Materials and methods. Spermogram parameters were assessed in accordance with the criteria of the 2010 WHO Guidelines, 5th edition, for the study and processing of human ejaculate two to three months after the patient received a negative polymerase chain reaction result of a nasopharyngeal swab for SARS-CoV-2 DNA. The intensity of free radical processes in seminal plasma was investigated by the method of chemiluminescence induced by ions of bivalent iron. Results. A decrease in sperm motility and an increase in the number of leukocytes were found in men with pathozoospermia who had undergone COVID-19 infection. There are lower levels of indicators such as ejaculate volume, total sperm concentration and the number of morphologically normal sperm forms. An increased ability to generate reactive oxygen species in seminal plasma was revealed in pathozoospermia and COVID-19.Conclusions. The results obtained indicate that SARS-CoV-2 affects the male reproductive system directly or indirectly and has a negative effect on male reproductive health, causing the activation of lipid peroxidation processes and spermatogenic insufficiency.","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125982793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implantation of an artificial urinary sphincter for urinary incontinence after radical prostatectomy (current aspects)","authors":"K. Ramazanov, N. Akhvlediani, A. V. Savchenko, D. Pushkar","doi":"10.17650/1726-9784-2022-23-1-21-29","DOIUrl":"https://doi.org/10.17650/1726-9784-2022-23-1-21-29","url":null,"abstract":"Stress urinary incontinence is a debilitating condition for men, caused in most cases by radical prostatectomy. Implantation of an artificial urinary sphincter is the “golden standard” of operative correction of this pathological condition in intermediate and severe cases. The article present literature review on comparative effectiveness and safety of implantation of an artificial urinary sphincter in men.The study objective is to study the current concepts of implantation of an artificial urinary sphincter in males, as well as its effectiveness and safety.Literature search was performed using PubMed/Medline and SCOPUS databases with the following key words: stress urinary incontinence, radical prostatectomy, artificial urinary sphincter. Inclusion criteria for the studies were follow-up longer than 12 months and definition of successful result as use of 1 or less liner a day; current studies on effectiveness of prosthesis implantation with large patient population were also included. Special focus was made on the historical development of artificial sphincters, problems of comparison of the effectiveness of male slings and artificial urinary sphincter, as well as simultaneous implantation of a sphincter and a penile prosthesis. We have used 43 articles complying with the inclusion criteria, our aim, and objectives.In the considered literature, effectiveness and safety of implantation were studied primarily (70 %) for the AMS 800 implant. It was noted that the frequency of revisions of its implantation can reach 30 %. For other models of artificial sphincters, the data is sparce. Comparison of the effectiveness of artificial sphincter and male sling implantations mostly was performed for patient groups with incomparable severity of urinary incontinence. Patients’ preferences and cost had the largest effect on the choice of single-step or subsequent implantation of a penile prosthesis and an artificial urinary sphincter.Implantation of АМS 800 is an effective but not perfectly safe method of operative treatment of stress urinary incontinence in males. Development and study of new prostheses of this category are necessary.","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124374085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging methods for seminal tract obstruction","authors":"T. Shatylko, S. Gamidov, N. Naumov, A. Al’ravashdekh, A. Popova, R. Safiullin","doi":"10.17650/1726-9784-2022-23-1-13-20","DOIUrl":"https://doi.org/10.17650/1726-9784-2022-23-1-13-20","url":null,"abstract":"Differential diagnosis between obstructive and non-obstructive azoospermia is an important task in clinical management of infertile patients. Chances of extracting sperm in obstructive azoospermia are high enough to inform the couple about favorable outcome of assisted reproductive technologies without resorting to donor sperm. Some forms of seminal tract obstruction can be corrected by microsurgical interventions or endoscopic resection of the ejaculatory ducts. Therefore, one of the objectives standing before imaging methods in reproductive andrology is the detection of these cases. In this literature review we present a detailed analysis of how to suspect and diagnose this form of azoospermia using imaging.","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128308649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for erectile dysfunction: known and unexpected facts (review)","authors":"S. Gamidov, R. I. Ovchinnikov, A. Popova, T. Shatylko","doi":"10.17650/1726-9784-2021-22-4-13-21","DOIUrl":"https://doi.org/10.17650/1726-9784-2021-22-4-13-21","url":null,"abstract":"The prevalence of erectile dysfunction (ED) among men over 50 years is 31-51 %. By 2025, the prevalence of ED is expected to increase to 322 million men worldwide. In Russia, according to academician D.Yu. Pushkar', ED suffers up to 89.9 %.In this regard, it seems very important to establish the causes of this condition. The purpose of this review is to assess the current state of the literature on the issue of risk factors leading to or associated with the development of ED.The presented works show that well-known factors play a role in the occurrence of ED: unfavorable environmental conditions, harmful lifestyle factors, chronic intoxication, obesity, genetic predisposition, deficiency of sex hormones and vitamins, diseases of the cardiovascular system, prostate and urethra, as well as drugs for their treatment. Also, new indicators in laboratory and instrumental studies that change with ED are considered.Among the well-known data, there are also some very original works devoted to this topic. The relationship between ED and reproductive disorders, psoriasis, periodontitis, human immunodeficiency virus infection and some drugs use is now being investigated, which is presented in this review.","PeriodicalId":368206,"journal":{"name":"Andrology and Genital Surgery","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132331871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}