Journal of Innovations in Cardiac Rhythm Management最新文献

{"title":"Initiation of a Wide QRS Complex Tachycardia with Alternating Ventriculoatrial Interval: What Is the Mechanism?","authors":"Can Ozkan, Ozcan Ozeke, Elif Hande Ozcan Cetin, Meryem Kara, Sona Huseynova, Ahmet Korkmaz, Firat Ozcan, Serkan Cay, Dursun Aras, Serkan Topaloglu","doi":"10.19102/icrm.2025.17021","DOIUrl":"10.19102/icrm.2025.17021","url":null,"abstract":"<p><p>The differential diagnosis for wide complex tachycardia includes all causes of narrow complex tachycardia with bundle branch block, all causes of narrow complex tachycardia with antegrade pre-excitation, ventricular tachycardia, and antidromic and other pre-excited reciprocating tachycardias. The variation in a specific intracardiac interval that causes a subsequent change in the tachycardia cycle length or another intracardiac interval can be diagnostic in these arrhythmias.</p>","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 2","pages":"6607-6611"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12962285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147378817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heart Rate Threshold Settings for Ventricular Tachycardia in Patients with Wearable Cardioverter-defibrillators.","authors":"Steve Ringquist, Nicole R Bianco, Patricia Tung","doi":"10.19102/icrm.2025.17022","DOIUrl":"10.19102/icrm.2025.17022","url":null,"abstract":"<p><p>The wearable cardioverter-defibrillator (WCD) uses programmable heart rate (HR) and detection time to determine the need for shock delivery, but the optimal ventricular tachycardia (VT) HR detection zone is unknown. The LifeVest™ (ZOLL Medical, Chelmsford, MA, USA) WCD has a default VT detection rate of 150 bpm. We found that 15% of appropriate shocks among WCD recipients were delivered for VT 150-170 bpm and that 30% of these patients experienced loss of consciousness. Based on these findings, a programmed VT detection threshold of 150 bpm should be considered.</p>","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 2","pages":"6627-6629"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12962278/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147378867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Small-vessel Disease in a Patient with Atrial Flutter: Unveiling a Potential Vascular Mechanism of Tachycardia-induced Cardiomyopathy.","authors":"Sebastian Weyand, Karin Klingel, Peter Seizer","doi":"10.19102/icrm.2026.17023","DOIUrl":"10.19102/icrm.2026.17023","url":null,"abstract":"<p><p>A 65-year-old man presented with new-onset exertional dyspnea. The predominant abnormality was a marked concentric thickening of the arteriolar walls with strong smooth muscle actin positivity, consistent with small-vessel disease (SVD). This case illustrates a potential mechanism of tachycardia-induced cardiomyopathy (TIC), in which SVD may contribute to impaired myocardial perfusion and reversible left ventricular dysfunction under persistent tachycardia.</p>","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 2","pages":"6613-6614"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12962279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147378786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Year in Review: Atrial Fibrillation 2025.","authors":"Lydia M Taranto, Ankur A Karnik, Rahul N Doshi","doi":"10.19102/icrm.2026.17014","DOIUrl":"10.19102/icrm.2026.17014","url":null,"abstract":"","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 1","pages":"6561-6569"},"PeriodicalIF":0.0,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12880193/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146143880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"End-of-the-year Review: Pediatric and Adult Congenital Heart Disease in 2025.","authors":"Johannes C von Alvensleben","doi":"10.19102/icrm.2026.17017","DOIUrl":"10.19102/icrm.2026.17017","url":null,"abstract":"","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 1","pages":"6574-6577"},"PeriodicalIF":0.0,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12880195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146143888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathogenesis of Oxidative Stress Biomarkers in Atrial Fibrillation: A Narrative Review.","authors":"Hira Naveed, Aqib Ishaque, Atif Nadeem, Aneeza Waris Hussain Rathore, Sadia Akhtar, Sara Haroon, Saira Rafaqat","doi":"10.19102/icrm.2026.17012","DOIUrl":"10.19102/icrm.2026.17012","url":null,"abstract":"<p><p>Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia. Although its pathogenesis remains incompletely elucidated, accumulating evidence implicates oxidative stress (OS) as a key contributor to the development of the arrhythmogenic substrate. OS may facilitate atrial remodeling through modulation of calcium-handling proteins and ion channel function, potentially promoting the initiation and maintenance of AF. This article summarizes the role of OS biomarkers such as 8-hydroxydeoxyguanosine (8-OHdG), glutathione peroxidase (GPx), advanced glycation end-products (AGEs), superoxide dismutase (SOD), malondialdehyde (MDA), isoprostanes (IsoPs), derivatives of reactive oxidative metabolites that oxidize reduced glutathione (E_h GSH) and cysteine, and advanced oxidation protein products (AOPPs) in the pathogenesis of AF. Plasma 8-OHdG levels progressively increase with advancing low-voltage area stages, indicating a strong association between oxidative DNA damage and the severity of atrial fibrosis. Also, the reduction in GPx activity appears to contribute to arrhythmogenic electrochemical disturbances and oxidative lipid damage, independent of dyslipidemia. The receptor for the AGE axis plays a part in arrhythmogenic structural atrial remodeling. Patients who develop post-surgical AF demonstrate paradoxically elevated SOD activity, possibly reflecting a compensatory antioxidant response to heightened OS. As serum MDA levels were not linked to the development of postoperative AF (POAF), it is possible that lipid peroxidation is not the primary cause of POAF pathogenesis. Even when AF patients are receiving anticoagulant medication, elevated 8-isoprostane levels are linked to thromboembolic events, in part because of changes in the fibrin clot structure. Each 10% increase in E_h GSH was associated with a 40% increase in the risk of incident AF. Future research is required on AOPPs in AF pathogenesis. Future investigations should aim to identify and characterize novel OS markers and evaluate their potential therapeutic relevance in the prevention and management of AF.</p>","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 1","pages":"6591-6606"},"PeriodicalIF":0.0,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12880196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146143920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence-driven Detection, Mapping, and Personalized Therapy for Atrial Fibrillation.","authors":"Daniel Joseph Gonzalez, Samhith Kambampati, Erick Godinez, Ishan Paranjpe, Kushal Chatterjee, Rahul Devathu, Aaryamaan Verma, Emma Sun, Connie Ma, Muhammad Fazal, Tina Baykaner","doi":"10.19102/icrm.2026.17011","DOIUrl":"10.19102/icrm.2026.17011","url":null,"abstract":"<p><p>Atrial fibrillation (AF), the most common arrhythmia worldwide, affects approximately 59 million people globally. It poses a significant health burden by increasing morbidity and mortality. Artificial intelligence (AI) is emerging as a potentially transformative technology across the AF care continuum. This review synthesizes current evidence and critically evaluates AI applications in AF management, including innovations in detection and screening using electrocardiography and wearables; advanced mapping techniques using signal processing and computational modeling to guide catheter ablation; machine learning-based prediction of treatment outcomes; and personalization of long-term therapy, such as anticoagulation. Key studies and trials illustrating AI's capabilities in improving diagnostic yield, refining ablation targets, and enhancing prognostic accuracy are analyzed. The potential for AI to facilitate integrated care pathways, such as the \"AF Better Care\" approach, is considered, balancing innovation against clinical practicality, rigorous validation, and workflow integration. While AI shows considerable potential to augment precision in AF management, significant challenges concerning data generalizability, model interpretability, clinical utility validation, and equitable implementation remain. Optimal integration requires careful alignment with clinical expertise and a focus on patient-centric outcomes. Addressing these challenges through collaborative efforts among clinicians, researchers, and technology developers will be essential to fully realize AI's promise in improving AF care. Future research should prioritize robust validation, transparent methodologies, and practical implementation strategies to ensure that AI effectively enhances patient outcomes.</p>","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 1","pages":"6578-6590"},"PeriodicalIF":0.0,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12880197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146143915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter from the Editor in Chief.","authors":"Devi Nair","doi":"10.19102/icrm.2026.17013","DOIUrl":"https://doi.org/10.19102/icrm.2026.17013","url":null,"abstract":"","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 1","pages":"A5-A6"},"PeriodicalIF":0.0,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12880191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146143927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 2025 Literature Review on Arrhythmias: Returning the Focus to Basic Science.","authors":"Sara Bushmen, Emily Collins, Andy C Kiser","doi":"10.19102/icrm.2025.17016","DOIUrl":"10.19102/icrm.2025.17016","url":null,"abstract":"","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 1","pages":"6570-6573"},"PeriodicalIF":0.0,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12880192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146143952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Centers for Medicare & Medicaid Services Approval of Cardiac Ablations in Ambulatory Surgery Centers: Challenges and Emerging Models Shaping the Future of Cardiac Electrophysiology.","authors":"Arash Aryana, Vijendra Swarup","doi":"10.19102/icrm.2026.17015","DOIUrl":"10.19102/icrm.2026.17015","url":null,"abstract":"","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 1","pages":"6557-6560"},"PeriodicalIF":0.0,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12880194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146143950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}