{"title":"Letter from the Editor in Chief.","authors":"Devi Nair","doi":"10.19102/icrm.2026.17036","DOIUrl":"10.19102/icrm.2026.17036","url":null,"abstract":"","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 3","pages":"A5-A6"},"PeriodicalIF":0.0,"publicationDate":"2026-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13068032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147676741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Termination of Ventricular Tachycardia by Prepotential Exit Block.","authors":"Ozcan Ozeke, Dursun Aras, Serkan Topaloglu","doi":"10.19102/icrm.2026.17034","DOIUrl":"10.19102/icrm.2026.17034","url":null,"abstract":"<p><p>Discrete prepotentials (PPs) mapped within the aortic sinuses of Valsalva are considered reliable targets for the ablation of idiopathic premature ventricular complexes (PVCs) and ventricular tachycardias. A critical conduction time is required for the PVC to manifest, as evidenced by a distinct isoelectric segment between the discrete PPs and the ventricular electrograms, consistent with the limitations imposed by the local refractoriness of the tissue at the exit site.</p>","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 3","pages":"6668-6670"},"PeriodicalIF":0.0,"publicationDate":"2026-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13068030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147677233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mustafa Lütfullah Ardıç, Halil Coskun, Hilmi Erdem Sumbul, Yahya Kemal Icen, Abdullah Eren Çetin, Mevlut Koç
{"title":"Flecainide Provides Comparable Rhythm Control Efficacy to Repeat Radiofrequency Ablation in Patients with Paroxysmal Atrial Fibrillation After Failed Cryoballoon Ablation.","authors":"Mustafa Lütfullah Ardıç, Halil Coskun, Hilmi Erdem Sumbul, Yahya Kemal Icen, Abdullah Eren Çetin, Mevlut Koç","doi":"10.19102/icrm.2026.17035","DOIUrl":"10.19102/icrm.2026.17035","url":null,"abstract":"<p><p>Class IC anti-arrhythmic drugs are primarily preferred for the rhythm control of atrial fibrillation (AF). In cases where ablation fails, the appropriate rhythm-control strategy is still unclear. In our study, we aimed to evaluate the efficacy of flecainide, propafenone, and radiofrequency ablation (RFA) as rhythm-control strategies in paroxysmal AF patients with failed cryoballoon ablation (CBA). In this cross-sectional study, 1120 patients who underwent CBA for paroxysmal AF between 2017 and 2024 were screened. Within this patient group, 230 patients with recurrent AF (≥3 months) after CBA were identified. A total of 120 patients (40 cases per treatment) who underwent rhythm control and received flecainide, propafenone, or RFA were finally included in the study. Study participants were then divided into three groups, receiving flecainide (group I), propafenone (group II), or RFA (group III). All patients were followed up for at least 1 year for AF recurrence, which was confirmed in 52 (43.2%) patients. The AF recurrence rates in groups I, II, and III were 35%, 75%, and 20%, respectively. Although the frequency of AF recurrence in groups I and III was statistically similar (<i>P</i> > .05), it was significantly lower in these groups than that in group II (<i>P</i> < .05). Group I patients were significantly more likely to use β-blockers than group II or III patients (<i>P</i> < .05). Patients with AF recurrence had a larger left atrial (LA) diameter and greater propafenone use. The number of patients who used flecainide and underwent RFA was lower in the AF recurrence group. In logistic regression analysis, LA diameter was found to be an independent predictor of AF recurrence (<i>P</i> = .002). In conclusion, based on the findings of our study, flecainide therapy can be used with an acceptable success rate in patients with recurrent AF after CBA.</p>","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 3","pages":"6644-6650"},"PeriodicalIF":0.0,"publicationDate":"2026-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13068028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147676632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Leadless Pacemaker for Sinus Pauses and Syncope in Pregnancy: A Feasible Alternative to Conventional Pacing.","authors":"Miki Yokokawa, Shaurya Srivasta, Ali H Sheikh","doi":"10.19102/icrm.2026.17032","DOIUrl":"10.19102/icrm.2026.17032","url":null,"abstract":"<p><p>Bradyarrhythmias with syncope during pregnancy present a complex and multifaceted challenge for both patients and health care providers. When device implantation is indicated for bradyarrhythmia-associated syncope during pregnancy, the procedure should be performed with particular attention to minimizing fluoroscopy exposure to ensure maternal and fetal safety. A 29-year-old woman at 15 weeks of gestation with sinus pauses presented with recurrent syncopal episodes. The patient underwent Micra™ AV leadless pacemaker implantation (Medtronic, Minneapolis, MN, USA) with a radiation exposure of 26.5 mGy and a total fluoroscopy time of 2 min, which is generally considered a negligible dose during pregnancy, based on the recommendations of the National Council on Radiation Protection and Measurements. In pregnant patients, a leadless pacemaker may offer a viable alternative to conventional pacing, primarily due to its reduced radiation exposure, shorter procedure time, minimally invasive approach, absence of transvenous leads, and lower risk of site infection.</p>","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 3","pages":"6637-6642"},"PeriodicalIF":0.0,"publicationDate":"2026-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13068034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147676715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Novel Low Right Atrial-approach Transseptal Puncture Technique for Large-bore Deflectable Sheaths: Enhancing Control, Precision, and Safety.","authors":"Esteban Martin Kloosterman","doi":"10.19102/icrm.2026.17031","DOIUrl":"10.19102/icrm.2026.17031","url":null,"abstract":"<p><p>The conventional transseptal puncture (TSP) technique, developed in the 1960s, remains a procedural standard but offers limited control when applied to contemporary large-bore deflectable sheaths. The objective of this study is to describe a novel low right atrial (RA)-approach TSP technique designed to optimize control, precision, and safety when using large-bore deflectable systems. This technique eliminates the need for superior vena cava (SVC) positioning and instead advances the deflectable sheath-dilator assembly from the low RA toward the interatrial septum under imaging guidance. The deflectable capabilities of the sheath, protected by the spiral or J-tip wire, enable atraumatic manipulation and precise targeting before puncture. This method was used in 63 consecutive procedures, including pulsed field ablation, left atrial appendage occlusion, and concomitant cases. All punctures were completed successfully without complications. The average time from inferior vena cava advancement to septal crossing was 2-3 min. This new low RA-approach TSP technique provides superior sheath control and maneuvering of large-bore deflectable systems, offering competitive safety and efficiency as an excellent alternative to conventional SVC-based approaches.</p>","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 3","pages":"6663-6667"},"PeriodicalIF":0.0,"publicationDate":"2026-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13068029/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147676455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Serhat Kesriklioglu, Ahmet Taha Sahin, Khaled Alwaled, Abdulhadi Elkadiki, Ahmet Lutfu Sertdemir, Enes Elvin Gul
{"title":"Feasibility of Left Bundle Branch Area Pacing via a Persistent Left Superior Vena Cava in a Patient with Repaired Ventricular Septal Defect.","authors":"Serhat Kesriklioglu, Ahmet Taha Sahin, Khaled Alwaled, Abdulhadi Elkadiki, Ahmet Lutfu Sertdemir, Enes Elvin Gul","doi":"10.19102/icrm.2026.17024","DOIUrl":"10.19102/icrm.2026.17024","url":null,"abstract":"<p><p>Persistent left superior vena cava (PLSVC) is the most common systemic venous anomaly and may complicate cardiac device implantation, particularly in patients with a history of congenital heart surgery. We report the case of a 16-year-old girl with a surgically repaired ventricular septal defect who developed complete heart block, necessitating conduction system pacing (CSP). This case highlights the feasibility of CSP in the presence of PLSVC and prior congenital heart surgery.</p>","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 2","pages":"6630-6632"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12962280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147378773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Atrioventricular Nodal Re-entrant Rhythm.","authors":"Sudipta Mondal, Nadeem Afroz Muslim, Debargha Dhua","doi":"10.19102/icrm.2026.17027","DOIUrl":"10.19102/icrm.2026.17027","url":null,"abstract":"<p><p>A 60-year-old male with a history of decompensated chronic liver disease and resolving hepatic encephalopathy was transferred for further evaluation following a witnessed episode of prolonged asystole. The patient's admission electrocardiogram showed spontaneous transitions between a borderline R-P narrow complex rhythm and sinus rhythm. The rhythm was observed to be easily terminated with ventricular overdrive pacing via the temporary catheter. We questioned what the mechanism of the rhythm may be.</p>","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 2","pages":"6633-6636"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12962282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147378805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Frequently Underappreciated Considerations in Anti-arrhythmic Drug Therapy.","authors":"James A Reiffel","doi":"10.19102/icrm.2026.17026","DOIUrl":"10.19102/icrm.2026.17026","url":null,"abstract":"<p><p>Anti-arrhythmic drugs (AADs) have been a mainstay of dysrhythmia control for over a century. Even in the current era of evolving ablation use and technology, AADs remain therapeutically important. Nonetheless, the effectiveness of AADs may be incomplete and/or adverse effects may limit their use despite efficacy. Ideally, to maximize the clinical profile of AADs, clinicians should be aware of the full array of their complexities and selection options. However, commonly, some of them seem to be frequently underappreciated. Among others, these include dosing intricacies, targeting therapy to the arrhythmia trigger, avoiding habitual choices of AAD selection, consideration of AAD combinations, and more. These factors are discussed in this paper as a means of improving AAD use by clinicians and tolerance by patients. Notably, it is only these issues that are the focus of this paper, which is not meant as a review of the pharmacologic profile of each of our AADs.</p>","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 2","pages":"6616-6621"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12962281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147378860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Saad Al-Shammari, Robert Spalding, Haider Al-Taii
{"title":"Premature Ventricular Complex-induced Full Pre-excitation in Wolff-Parkinson-White Syndrome: A Case Report.","authors":"Ali Saad Al-Shammari, Robert Spalding, Haider Al-Taii","doi":"10.19102/icrm.2026.17025","DOIUrl":"10.19102/icrm.2026.17025","url":null,"abstract":"<p><p>In this report, we present a unique case of a patient with Wolff-Parkinson-White (WPW) syndrome who demonstrated premature ventricular complexes followed by fully pre-excited beats, highlighting an uncommon electrophysiologic phenomenon, and discuss its diagnostic and therapeutic implications.</p>","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 2","pages":"6622-6626"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12962283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147378850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter from the Editor in Chief.","authors":"Devi Nair","doi":"10.19102/icrm.2025.17028","DOIUrl":"10.19102/icrm.2025.17028","url":null,"abstract":"","PeriodicalId":36299,"journal":{"name":"Journal of Innovations in Cardiac Rhythm Management","volume":"17 2","pages":"A5-A6"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13020892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147575675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}