Clinical Nutrition Open Science最新文献

{"title":"Leveraging culinary nutrition interventions and contextual factors to combat child growth failure in mining communities for maximum impact","authors":"Herbert Tato Nyirenda,&nbsp;David Mulenga,&nbsp;Hilda Nyambe-Silavwe","doi":"10.1016/j.nutos.2024.12.005","DOIUrl":"10.1016/j.nutos.2024.12.005","url":null,"abstract":"<div><h3>Background and aims</h3><div>A growing body of evidence supports the effectiveness of culinary nutrition interventions; however, there is limited research on the analytical techniques, components, and the combined impact of these interventions alongside contextual factors in addressing child growth failure. This paper examines the combined effect of culinary nutrition interventions and contextual factors in reducing child growth failure within mining communities.</div></div><div><h3>Methods and materials</h3><div>This study employed a cross-sectional design, targeting children under the age of five and their caregivers. A total of 706 participants were included, selected using a systematic random sampling technique. Data were collected through structured questionnaires, direct child measurements, and structured interviews. Anthropometric data were analysed using the WHO growth standards. Statistical analysis involved descriptive statistics and logistic regression, with an emphasis on examining interaction effects.</div></div><div><h3>Results</h3><div>The results revealed that 34.7% of the children experienced growth failure while 55% of the caregivers participated in culinary nutrition programs. Children whose caregivers participated in culinary programs had significantly lower odds of experiencing growth failure (OR = 0.69∗∗, <em>P</em> = 0.019, 95% CI). Factorial analysis demonstrated that the impact of culinary interventions on reducing child growth failure was more pronounced in households with adequate food (OR = 0.46∗, <em>P</em> = 0.085, 90% CI), households with vegetable gardens (OR = 0.50∗∗, <em>P</em> = 0.005, 95% CI), children with a good appetite (OR = 0.44∗∗, <em>P</em> = 0.032, 95% CI), households practicing food preservation (OR = 0.52∗, <em>P</em> = 0.054, 90% CI), and those producing their own food (OR = 0.46∗∗, <em>P</em> = 0.016, 95% CI).</div></div><div><h3>Conclusion</h3><div>The findings highlight the synergistic impact of culinary nutrition interventions alongside key factors in addressing child growth failure, particularly in mining communities. It emphasizes the importance of integrating both nutritional programs and the social environment to effectively combat child malnutrition and stunting in these vulnerable populations.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"59 ","pages":"Pages 87-97"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of acute malnutrition among 6 to 59-months children in public health facilities","authors":"Abdilahi Ibrahim Muse,&nbsp;Mohamed Omar Osman,&nbsp;Ahmed Mohammed Ibrahim","doi":"10.1016/j.nutos.2024.12.004","DOIUrl":"10.1016/j.nutos.2024.12.004","url":null,"abstract":"<div><h3>Background</h3><div>Acute malnutrition is a nutritional insufficiency resulting from either inadequate energy or protein intake. It is categorized into severe acute malnutrition and moderate acute malnutrition. Globally, acute malnutrition is still a prevalent public health issue.</div></div><div><h3>Objective</h3><div>To identify determinants of acute malnutrition among 6 to 59-month-old children in public health facilities.</div></div><div><h3>Methods and materials</h3><div>A hospital-based, unmatched case-control study was conducted from 1^st March to 30^th April 2023. Three hundred ninety (130 cases and 260 controls) participants were included in the study. Data was collected using pretested, semi-structured questionnaires by using Kobo Collect. The analysis was done using SPSS version 20. Both bi-variable and multivariable logistic regressions were done. An adjusted odds ratio with a 95% confidence interval was computed to determine levels of significance. All variables with a p-value less than 0.05 were declared as determinants of acute malnutrition.</div></div><div><h3>Results</h3><div>In this study, estimated average family income, 1001–5000 Ethiopian birr (AOR=3.32, 95%CI=1.27, 8.72), 5001–10000 Ethiopian birr (AOR=3.82, 95%CI=1.56, 9.36), family size ≥5 (AOR=2.33, 95%CI=1.33, 4.084), private employee (AOR=4.62, 95%CI=2.18, 9.76), government employee (AOR=3.77, 95%CI=1.69, 8.42), non-governmental organization employee (AOR= 17.14, 95%CI=2.53, 16.27), food insecurity (AOR=1.46, 95%CI=1.08,1.97), bottle-feeding (AOR=2.64, 95%CI=1.22,5.68), and lack of latrines (AOR=3.30, 95%CI=1.04, 10.49) were identified as determinants of acute malnutrition.</div></div><div><h3>Conclusion</h3><div>Estimated average family income, family size, lack of latrine, maternal or caregiver occupation, food security status, and bottle feeding were all predictors of acute malnutrition in this study. Promoting exclusive breastfeeding, raising awareness about the health issues of bottle-feeding and open defecation, improving access to clean water and sanitation, strengthening healthcare systems, and encouraging collaboration among agencies can effectively address acute malnutrition.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"59 ","pages":"Pages 56-67"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors of postoperative infections in patients with iatrogenic gallbladder perforation during laparoscopic cholecystectomy","authors":"Shinya Urakawa ,&nbsp;Toshiya Michiura ,&nbsp;Shinji Tokuyama ,&nbsp;Yasunari Fukuda ,&nbsp;Yasuaki Miyazaki ,&nbsp;Nobuyasu Hayashi ,&nbsp;Kazuo Yamabe","doi":"10.1016/j.nutos.2024.11.004","DOIUrl":"10.1016/j.nutos.2024.11.004","url":null,"abstract":"<div><h3>Background &amp; Aims</h3><div>Iatrogenic gallbladder perforation (IGP) frequently occurs during laparoscopic cholecystectomy (LC). The study aimed to investigate the risk factors including postoperative treatments (i.e., antibiotics and drainage) of postoperative infections in patients with IGP during LC.</div></div><div><h3>Methods</h3><div>Of 539 patients underwent LC, 121 consecutive patients with IGP were enrolled retrospectively. Infectious complications were classified into surgical site infections, distant infections, and infections with unknown origin. The association between postoperative infections and clinical factors.</div></div><div><h3>Results</h3><div>Of 121 patients, 20 patients (16.5%) had infectious complications. The infection-positive group of patients with IGP had a higher frequency of diabetes mellitus (positive vs. negative group = 50% (10/20) vs. 17.7% (18/101), <em>P</em> = 0.0018) and lower preoperative albumin (3.8 vs. 4.1 g/dL, <em>P =</em> 0.0081) than the infection-negative group. However, there were no associations between the presence of infectious complications and postoperative management for IGP such as antibiotics (positive vs. negative group = 35% (7/20) vs. 40.6% (41/101), <em>P</em> =0.64), drainage (45% (9/20) vs. 29.7% (30/101), <em>P</em> =0.12), and no treatment (20% (4/20) vs. 29.7% (30/101), <em>P</em> =0.38). Multivariate analysis showed that lower preoperative albumin (OR 4.90, 95% CI 1.20–20.0, <em>P =</em> 0.027) and the presence of diabetes mellitus (OR 5.49, 95% CI 1.62–18.6, <em>P =</em> 0.0063) were independent factors of infectious complications.</div></div><div><h3>Conclusions</h3><div>Diabetes mellitus and preoperative malnutrition were associated with postoperative infections in patients with IGP during LC. On the other hand, postoperative management for IGP had no significant impact on the presence of infectious complications.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"59 ","pages":"Pages 9-16"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A six-month randomized controlled pilot study evaluating the effects of an oral nutrition supplement on children's growth patterns","authors":"Robert Frument ,&nbsp;Ceci Mao ,&nbsp;Becca Li ,&nbsp;Clara Chan ,&nbsp;Diana Pozo ,&nbsp;John Ademola ,&nbsp;Michael Milobsky","doi":"10.1016/j.nutos.2024.11.006","DOIUrl":"10.1016/j.nutos.2024.11.006","url":null,"abstract":"<div><h3>Background and aims</h3><div>Pilot study to evaluate the effect of oral nutrition supplementation (ONS) among children and adolescents.</div></div><div><h3>Methods</h3><div>A prospective, randomized trial of nutritional supplementation was conducted among 32 children and adolescents 4–17 years of age. Change in height and weight standard deviation score (SDS) as well as measures of body composition were measured 3 times over a six month study period. Participants in the treatment arm were given ONS to take once a day, 5 days a week; the controls continued their usual diet. Three study visits were conducted to collect measurements for all subjects: baseline, 3 months and 6 months. Univariate, bivariate and multivariate analyses were conducted to estimate the effect of the powder supplement on height velocity as measured by standard deviation score (SDS) as well as static body composition measurements (lean body mass, fat-free mass, body mass index (BMI)) and collagen X concentration in the urine.</div></div><div><h3>Results</h3><div>The mean change in height SDS increased in both the treatment and control groups, but only the treatment group achieved statistical significance (SDS 0.09, 95% Confidence Interval (CI) 0.04, 0.15, p=0.0028). The mean increase in height in the treatment group was 2.94 cm (95% CI 2.22, 3.66) compared to 2.23 cm (95% CI 1.34, 3.12) in the control group. Changes in the secondary outcome measures (BMI, fat mass, lean mass and collagen X) did not reach statistical significance. The most parsimonious linear regression model (p&lt;0.0001, Adj R-squared 0.6950) suggests that the ONS afforded a 0.281 cm growth advantage when controlling for baseline age, sex, height, and collagen X.</div></div><div><h3>Conclusions</h3><div>The change in height SDS was statistically significant only in the treatment group (p=0.0028). While both groups grew, as expected, the multivariate model suggests an advantage for the treatment group when controlling for baseline characteristics.</div></div><div><h3>Clinical trial registry number</h3><div><span><span>https://clinicaltrials.gov/study/NCT06329388</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"59 ","pages":"Pages 17-30"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of vitamin D and vitamin A supplementation on T cell levels of patients with pneumosepsis: A double-blind, randomized clinical trial","authors":"Abolfazl Jokar ,&nbsp;Alireza Sistani ,&nbsp;Ghasem Mosayebi ,&nbsp;Atefeh Poyandeh","doi":"10.1016/j.nutos.2024.12.003","DOIUrl":"10.1016/j.nutos.2024.12.003","url":null,"abstract":"<div><h3>Background &amp; aims</h3><div>Pneumosepsis is a global healthcare challenge associated with substantial morbidity and mortality rates. Its pathogenesis involves intricate interactions among host factors, pathogens, and immune dysregulation. Vitamins A and D are crucial for immune function, acting as regulators and cofactors in immune cell development and function. Given these roles, this study aimed to assess the impact of combined vitamin D and A supplementation on T cell levels in pneumosepsis patients.</div></div><div><h3>Methods</h3><div>This double-blind clinical trial enrolled 84 pneumosepsis patients who were randomly assigned to four groups after demographic data collection. Intervention: Group 1 received standard treatment plus 300,000 IU of vitamin D and 50,000 IU of vitamin A. Group 2 received standard treatment plus 300,000 IU of vitamin D. Group 3 received standard treatment plus 50,000 IU of vitamin A. Group 4 received only standard treatment. Main outcome measures: Vital signs were monitored every 6 hours, and T-cell count, ESR, CRP, creatinine, urea, and uric acid levels were assessed at 0, 24, 48, and 72 hours.</div></div><div><h3>Results</h3><div>Initially and one day post-intervention, vital signs and blood factors showed no significant differences among the groups. However, on days two and three post-intervention, the combined vitamin D and A group exhibited significantly lower levels compared to other groups. Lymphocytes expressing CD3+, CD4+, CD25+, CD3,4+, and CD3,4,25+ markers significantly differed in the combined vitamin A + D group versus the control. No significant differences were noted in lymphocyte percentages between the combined vitamin A + D group and those receiving only vitamin D or A.</div></div><div><h3>Conclusion</h3><div>This study underscores the potential benefits of concurrent vitamin D and A supplementation in reducing symptoms among pneumosepsis patients, particularly in modulating key physiological parameters and immune responses.</div></div><div><h3>Trial registration</h3><div>This study is registered on Iranian Registry of Clinical Trials (IRCT) under identifieron IRCT20130424013110N10. (The registration date: Jul 6, 2020).</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"59 ","pages":"Pages 122-133"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence and human microbiome: A brief narrative review","authors":"Danielle Cristina Fonseca ,&nbsp;Gabriel da Rocha Fernandes ,&nbsp;Dan Linetzky Waitzberg","doi":"10.1016/j.nutos.2024.12.009","DOIUrl":"10.1016/j.nutos.2024.12.009","url":null,"abstract":"<div><div>The human microbiome is a complex ecosystem that influences various functions within the human body. With technological advancements, microbiome studies have expanded, bringing forth the challenge of interpreting large volumes of data, which require robust tools based on artificial intelligence (AI). Subfields of AI, including machine learning (ML) and deep learning (DL), have been applied to analyze complex and large-scale datasets, such as microbiome data, with particular utility in identifying and predicting microorganisms in different health conditions.</div><div>In the era of Big Data, integrating AI with sequencing techniques allows for a more detailed analysis of microbial data, enabling the detection of complex patterns and prediction of health states. However, AI use in this field still faces challenges, such as data heterogeneity (e.g., different sequencing platforms produce data with varying quality and resolution) and the need for data collection and analysis standardization processes (e.g., lack of standardized protocols for sample collection and data analysis).</div><div>Despite these challenges, AI has significant potential to revolutionize microbiome research. It can assist in identifying biomarkers for diagnostics and treatments, advancing personalized nutrition and precision medicine. The future of this field will depend on the continued development of technologies and collaboration among multidisciplinary teams.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"59 ","pages":"Pages 134-142"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diet management of older subjects with Oropharyngeal Dysphagia: The efficacy of ready-made texture-modified and fortified meals","authors":"Nikolina Jukic Peladic ,&nbsp;Paolo Orlandoni ,&nbsp;Laura Bartoloni ,&nbsp;Giulia Giulioni ,&nbsp;Claudia Venturini ,&nbsp;Alessia Fumagalli","doi":"10.1016/j.nutos.2024.12.008","DOIUrl":"10.1016/j.nutos.2024.12.008","url":null,"abstract":"<div><h3>Background</h3><div>In-home prepared texture-modified diets are not efficient in preventing the consequences of Oropharyngeal Dysphagia (OD); malnutrition and aspiration pneumonia. Difficulties with their preparation and administration aggravate also the burden of caregivers. This study investigated whether the ready-made texture-modified meals, fortified with amino acids and Vitamin D, may guarantee safe and efficient management of meals in older subjects with OD and facilitate patient management.</div></div><div><h3>Methods</h3><div>Patients who were assessed for dysphagia and nutritional status at the Clinical Nutrition Unit of Ancona and the <em>Pneumology Unit</em> of Casatenovo (LC) of the National Institute of Health and Science on Aging (IRCCS) INRCA and diagnosed with level 4 severity of OD according to IDDSI framework, were invited to use at lunch, for seven consecutive days, the ready-made fortified meals. Face-to-face and phone interviews were used to collect the socio-demographic data and testimonies of 30 out-hospital patients with OD and their formal and informal caregivers in order to assess the safety and liking of products. Simple descriptive statistics were used to summarize the results of the interviews.</div></div><div><h3>Results</h3><div>Out of 493 tastings, only 20 (4%) were interrupted because of an minor adverse event. Ready-made meals, and sweet desserts in particular, were appreciated by subjects with OD; 95% of dishes were consumed entirely, thus ensuring the satisfaction of the protein-calorie needs of patients. Ready-made products positively affected caregiving (75%), especially because the food administration was less time-consuming (90%).</div></div><div><h3>Conclusions</h3><div>Ready-made texture-modified fortified food seem promising in ensuring the improvement in patients' safety and easing the caregivers' tasks. The specific needs of patients with OD relative to diet consistency and protein-calorie needs should be defined by healthcare staff while the meeting between the needs of patients and the offer of ready-made products should be mediated by the mandatory use of a universal scale for the definition of diet texture.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"59 ","pages":"Pages 98-110"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of pulsative flushing on Candida albicans growth inside three-way stopcocks","authors":"Sachiko Omotani,&nbsp;Misaki Umemura,&nbsp;Marie Miki,&nbsp;Yota Taniguchi,&nbsp;Sadahito Masui,&nbsp;Shino Niki,&nbsp;Yasutoshi Hatsuda,&nbsp;Michiaki Myotoku","doi":"10.1016/j.nutos.2024.12.001","DOIUrl":"10.1016/j.nutos.2024.12.001","url":null,"abstract":"<div><h3>Background &amp; Aim</h3><div><em>Candida albicans</em> (<em>C. albicans</em>) is a common causative pathogen of catheter-related bloodstream infections, resulting in difficult-to-treat candidiasis. Moreover, fluid infusion by total parenteral nutrition (TPN) is commonly combined with lipid emulsion administration from a side tube. We evaluated the growth of <em>C. albicans</em> in closed three-way stopcocks used for simultaneous administration of TPN infusions and lipid emulsions. In addition, the effect of flushing on <em>C. albicans</em> growth was examined.</div></div><div><h3>Methods</h3><div>A TPN infusion solution and a lipid emulsion were tested using two different closed-type three-way stopcocks. The strain used was <em>C</em>. <em>albicans</em> IFM 61197. Simultaneous administration of the TPN infusion solution (2,000 mL over 24 h) and the lipid emulsion with <em>C. albicans</em> (100 mL over 4 h) were simultaneously administered using the piggyback method and an infusion pump. Flushing with physiological saline was performed via the side tube of the three-way stopcock after lipid emulsion administration. The flushing volumes were 0, 5, 10, and 20 mL. Continuous flushing (CF) and pulsative flushing (PF) were used as flushing methods. The infusion fluid remaining in the three-way stopcock was sampled immediately before completing lipid emulsion administration and 24 h after beginning administration of the TPN infusion solution. From these samples, colony-forming unit (CFU) counts were determined. In addition, after the last sampling at 24 h, the stopcock interior was washed with phosphate-buffered saline, and CFU counts determined.</div></div><div><h3>Results</h3><div>Without flushing, <em>C. albicans</em> grew in the two types of three-way stopcocks. When flushing with saline after lipid emulsion administration was performed, growth of <em>C. albicans</em> was lower than without flushing. Increasing flushing volume and using PF as the flushing method were found to decrease <em>C. albicans</em> growth in the three-way stopcocks.</div></div><div><h3>Conclusion</h3><div>As <em>C. albicans</em> growth was reduced inside the three-way stopcock by flushing after lipid emulsion administration, PF was demonstrated as effective against <em>C. albicans</em> growth within the three-way stopcocks. However, experimental results varied substantially, despite using the same experimental procedures. Therefore, proper flushing requires an appropriate level of skill and training to appropriate infusion solution management and operation to prevent microbial contamination.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"59 ","pages":"Pages 45-55"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decrease in phase angle after Roux-en-Y gastric bypass is related to increase of anti-inflammatory status","authors":"Amanda Cristina Araújo Gomes ,&nbsp;Amanda Machado Fiorotti ,&nbsp;Amanda Motta de Bortoli ,&nbsp;Beatriz Bobbio de Brito ,&nbsp;João Arthur Souza Fiorido ,&nbsp;Luciane Bresciani Salaroli ,&nbsp;Andressa Bolsoni Lopes ,&nbsp;Fabiano Kenji Haraguchi","doi":"10.1016/j.nutos.2025.01.002","DOIUrl":"10.1016/j.nutos.2025.01.002","url":null,"abstract":"<div><h3>Background &amp; Aims</h3><div>Phase angle (PhA) has been used as a prognostic indicator in various clinical conditions. However, its relationship with inflammatory state during obesity treatment is less known. This study investigated the relationship between PhA and inflammatory parameters in patients undergoing Roux-en-Y gastric bypass (RYGB).</div></div><div><h3>Methods</h3><div>This is a prospective longitudinal study with patients from the Bariatric and Metabolic Surgery Program of a university hospital. Analyses were conducted pre-RYGB and about two and six months post-RYGB. Assessments included serum levels of alpha-1-acid glycoprotein (AGP), C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α), adiponectin, and resistin, as well as anthropometric data and body composition. Data were analyzed using the one-way repeated measures ANOVA or Friedman's test, followed by Tukey's post hoc test. Relationship between PhA and biochemical and body parameters were assessed using the Spearman or Pearson correlation coefficient. A significance level of 5% was adopted.</div></div><div><h3>Results</h3><div>Final sample was composed of 23 subjects (87% women), aged 40.6 ± 10.7 years. A significant decrease in PhA values accompanied by an improvement in inflammatory parameters were observed post-RYGB (p&lt;0.05). PhA values was inversely correlated with serum adiponectin concentrations (r= −0.376, p&lt;0.05). In addition, BMI and fat-mass were also significantly correlated with serum adiponectin (r= −0.264 for BMI and r= −0.277 for fat-mass, p&lt;0.05) and TNF-alpha (r= 0.338 for BMI and r= 0.335 for fat-mass, p&lt;0.05), whereas serum resistin was correlated only with fat-mass (r= 0.245, p&lt;0.05).</div></div><div><h3>Conclusions</h3><div>Data suggest that the decrease in PhA values during six months post-RYGB may indicate a concomitant improvement of anti-inflammatory state.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"59 ","pages":"Pages 159-170"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating Traffic Light Diet System via food analysis in Android app for adolescent nutrition education: A strategy to reduce sugar, salt, and fat consumption","authors":"Trias Mahmudiono ,&nbsp;Alinda Rahmani ,&nbsp;Nur Alifia Hera ,&nbsp;Erwanda Anugrah Permatasari ,&nbsp;Nadia Syfa Zainurrahmah ,&nbsp;Ni Made Ayu Rachel Rasheeta Nuka ,&nbsp;Theresa Winona Wijaya ,&nbsp;Wanda Nurul Asifah","doi":"10.1016/j.nutos.2024.10.014","DOIUrl":"10.1016/j.nutos.2024.10.014","url":null,"abstract":"<div><h3>Introduction</h3><div>In today's global food consumption trend, high sugar, salt, and fat dominate diets, especially among adolescents who frequently utilize online food ordering systems. Monitoring nutritional intake has thus become increasingly crucial. The Traffic Light Diet application serves as a tool to help track the nutritional content of online food purchases. This study aimed to enhance adolescent knowledge and attitudes towards healthier food choices.</div></div><div><h3>Method</h3><div>Adopting a quasi-experimental research design, the study employed a pre-test and posttest approach for both control and intervention groups. The sample comprised 110 participants from Airlangga University, aged 18–25 years, possessing Android devices capable of downloading the application. Participants were recruited and randomly allocated, with data collected through self-reported questionnaires and analyzed using independent and dependent t-tests through the SPSS application.</div></div><div><h3>Results</h3><div>Significant effects were observed in knowledge levels following nutritional education provision in both groups. However, no significant difference was found in attitudes posteducation. Specifically, the control group showed no significant difference in attitudes, whereas the intervention group did.</div></div><div><h3>Discussion</h3><div>While both groups demonstrated improvements in knowledge and attitude posteducation, the control group exhibited higher scores. Although there was a significant effect between nutrition education and knowledge, the impact on attitudes was insignificant in the control group. This fact maybe due to the differences between participant baseline characteristic such an educational background.</div></div><div><h3>Conclusion</h3><div>These findings suggest the Traffic Light Diet app is useful but has room for improvement to better influence attitudes towards nutrition among participants. Although there was a significant effect between nutrition education and knowledge, the impact on attitudes was insignificant in the control group. This fact maybe due to the differences between participant baseline characteristic such an educational background.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"59 ","pages":"Pages 206-215"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143095287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}