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Dietary patterns and depressive symptoms among menopausal women 绝经期妇女的饮食模式和抑郁症状
Clinical Nutrition Open Science Pub Date : 2025-04-24 DOI: 10.1016/j.nutos.2025.04.007
Oiendrila Baroi, Md Monir Hossain Shimul, Mare- Cha, Salamat Khandker
{"title":"Dietary patterns and depressive symptoms among menopausal women","authors":"Oiendrila Baroi,&nbsp;Md Monir Hossain Shimul,&nbsp;Mare- Cha,&nbsp;Salamat Khandker","doi":"10.1016/j.nutos.2025.04.007","DOIUrl":"10.1016/j.nutos.2025.04.007","url":null,"abstract":"<div><h3>Backgrounds and aims</h3><div>Menopausal women experience physiological and psychological challenges, with depression being a prevalent concern. Dietary intake has been linked to mental health outcomes, yet evidence from low- and middle-income countries, including Bangladesh, remains limited. This study was carried out to find out the association between dietary patterns and depressive symptoms among menopausal women from two distinct socioeconomic groups in Dhaka.</div></div><div><h3>Methods</h3><div>A cross-sectional study of 310 menopausal women in Dhaka was conducted using systematic random sampling from July 2024 to October 2024. Data were collected using a semi-structured questionnaire, the Major Depression Inventory (MDI) scale was used to assess depressive symptoms. Chi-square tests and confidence interval were performed to assess associations between variables.</div></div><div><h3>Results</h3><div>Significant socioeconomic disparities were observed between selected groups (housing society and slum residents). Housing society residents had greater access to nutrient-rich foods, consuming fruits daily (94.83% vs. 0%, <em>P</em> &lt; 0.001) and milk weekly (46.45% vs. 1.93%, <em>P</em> &lt; 0.001). In contrast, slum residents had a higher intake of leafy vegetables (77.41% vs. 54.19%, <em>P</em> = 0.011) and Pangus fish (69.03% vs. 27.74%, <em>P</em> &lt; 0.001). Meal skipping was more frequent among slum dwellers (49.02% vs. 20.64%, <em>P</em> &lt; 0.001). Severe depression was significantly higher in slum residents (47.74% vs. 36.12%, <em>P</em> = 0.038), and moderate depression followed a similar trend (39.35% vs. 29.03%, <em>P</em> = 0.025).</div></div><div><h3>Conclusions</h3><div>Socioeconomic status significantly influences dietary intake and depressive symptoms among menopausal women in Bangladesh. Nutritional education and mental health services may be initiated for slum dwellers.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 231-240"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143895533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Are ultra-processed plant-based meats better than the alternative? 超加工的植物性肉类比其他替代品更好吗?
Clinical Nutrition Open Science Pub Date : 2025-04-23 DOI: 10.1016/j.nutos.2025.04.005
Michael Greger
{"title":"Are ultra-processed plant-based meats better than the alternative?","authors":"Michael Greger","doi":"10.1016/j.nutos.2025.04.005","DOIUrl":"10.1016/j.nutos.2025.04.005","url":null,"abstract":"<div><div>Studies link high consumption of ultra-processed foods to increased risks of a variety of adverse health outcomes, including all-cause mortality. However, these associations appear to be driven largely by sweetened beverages and processed meats, raising the possibility that plant-based meats (PBM) could ironically offer a solution to the ultra-processed foods problem. Unlike other ultra-processed foods, PBM rated as healthier than the foods they are intended to substitute and similarly countervail other negative criteria typical of ultra-processed products. Compared with PBM, conventional meat has the inferior nutrient profile, higher calorie density, and more missing phytonutrients, and results in less satiety and more weight gain, gut dysbiosis, and oxidative stress. With PBM, insulin resistance and inflammation outcomes are similar or superior to meat, depending on the PBM tested, and heat-induced toxins and harmful additives depend on the chemicals in question. Other advantages of PBM include lower potential cancer risk and enhanced food safety. The lowering of LDL cholesterol from the partial replacement of meat with PBM could alone potentially save thousands of lives a year in the United States and billions of healthcare dollars. Whole plant foods fare even better, but PBM appear to be the rare ultra-processed exception in that they are preferable to the foods they were designed to replace.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 241-252"},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143898946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urolithin A supplementation to improve endothelial and cerebrovascular function in middle-aged adults with obesity: Study protocol for a double-blind placebo-controlled randomized study 补充尿素A改善中年肥胖患者内皮和脑血管功能:一项双盲安慰剂对照随机研究的研究方案
Clinical Nutrition Open Science Pub Date : 2025-04-22 DOI: 10.1016/j.nutos.2025.04.004
Ana Clara da C. Pinaffi-Langley , Camila B. Pinto , Zsofia Szarvas , Anna Peterfi , Zalan Kaposzta , Peter Mukli , Mihaly Muranyi , Cameron D. Owens , Cheryl Adams , Ali Shahriari , Henry Kinnard Jr. , Bryan Ticer , Leah Anderson , Stefano Tarantini , Yan Daniel Zhao , Norman G. Hord , Andriy Yabluchanskiy
{"title":"Urolithin A supplementation to improve endothelial and cerebrovascular function in middle-aged adults with obesity: Study protocol for a double-blind placebo-controlled randomized study","authors":"Ana Clara da C. Pinaffi-Langley ,&nbsp;Camila B. Pinto ,&nbsp;Zsofia Szarvas ,&nbsp;Anna Peterfi ,&nbsp;Zalan Kaposzta ,&nbsp;Peter Mukli ,&nbsp;Mihaly Muranyi ,&nbsp;Cameron D. Owens ,&nbsp;Cheryl Adams ,&nbsp;Ali Shahriari ,&nbsp;Henry Kinnard Jr. ,&nbsp;Bryan Ticer ,&nbsp;Leah Anderson ,&nbsp;Stefano Tarantini ,&nbsp;Yan Daniel Zhao ,&nbsp;Norman G. Hord ,&nbsp;Andriy Yabluchanskiy","doi":"10.1016/j.nutos.2025.04.004","DOIUrl":"10.1016/j.nutos.2025.04.004","url":null,"abstract":"<div><h3>Background &amp; Aims</h3><div>Obesity-related mitochondrial dysfunction initiates and exacerbates endothelial dysfunction, which in turn contributes to the development of several diseases, such as cardiovascular disease and cognitive impairment. Urolithin A (UroA) is a polyphenol-derived microbial metabolite with mitophagy activator activity. Although the safety, pharmacokinetics, and effects of UroA supplementation on muscle health have been investigated in humans, its potential to mitigate endothelial dysfunction in obese adults remains unknown. Thus, this protocol details the procedures of a study designed to investigate the effect of 4 weeks of UroA supplementation on endothelial and cerebrovascular function in middle-aged adults with obesity.</div></div><div><h3>Methods</h3><div>This study is a placebo-controlled, double-blind, randomized, parallel interventional trial. Eligible participants are between 40–64 years old and have a BMI ≥30 kg/m<sup>2</sup>. Enrolled participants are randomized to receive active (1,000 mg of UroA daily) or control (placebo) intervention for 4 weeks. Before and after the intervention, they undergo peripheral micro- and macrovascular endothelial function and cerebrovascular function assessments.</div></div><div><h3>Results</h3><div>We expect that those who receive UroA supplementation will have a significant improvement in endothelial and cerebrovascular function compared with those who receive placebo.</div></div><div><h3>Conclusion</h3><div>The results of this trial will provide important insights into the effect of UroA on endothelial dysfunction in adults with obesity.</div></div><div><h3>Trial registration</h3><div>This study was prospectively registered at <span><span>ClinicalTrials.gov</span><svg><path></path></svg></span> on June 26, 2023 (NCT05921266).</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 217-230"},"PeriodicalIF":0.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143888023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutritional status and intestinal parasitism determinants of cognitive performance among secondary school students in South-East Nigeria 尼日利亚东南部中学生认知表现的营养状况和肠道寄生决定因素
Clinical Nutrition Open Science Pub Date : 2025-04-18 DOI: 10.1016/j.nutos.2025.04.003
Uzochukwu G. Ekeleme, Uchechukwu M. Chukwuocha, Christopher Chike A. Okereke, Chidinma O. Akanazu, Queeneth C. Onuoha, Ijeoma G. Chukwuemeka, Chiamaka C. Ogujiuba, Chigozie C. Ukachukwu, Chinwendu L. Opara, Amarachi B. Nwokoro
{"title":"Nutritional status and intestinal parasitism determinants of cognitive performance among secondary school students in South-East Nigeria","authors":"Uzochukwu G. Ekeleme,&nbsp;Uchechukwu M. Chukwuocha,&nbsp;Christopher Chike A. Okereke,&nbsp;Chidinma O. Akanazu,&nbsp;Queeneth C. Onuoha,&nbsp;Ijeoma G. Chukwuemeka,&nbsp;Chiamaka C. Ogujiuba,&nbsp;Chigozie C. Ukachukwu,&nbsp;Chinwendu L. Opara,&nbsp;Amarachi B. Nwokoro","doi":"10.1016/j.nutos.2025.04.003","DOIUrl":"10.1016/j.nutos.2025.04.003","url":null,"abstract":"&lt;div&gt;&lt;div&gt;Adolescents represent a critical population in public health research because their well-being has significant implications for future societal outcomes. This study focuses on the nutritional status and intestinal parasitism determinants of cognitive performance among secondary school students in South-East Nigeria. A cross-sectional design was used involving 481 secondary school students in five states in southeastern Nigeria. The sample included both middle and upper secondary school students from different socioeconomic backgrounds and school types. Data collection included administration of a comprehensive questionnaire, taking anthropometric measurements, assessing nutritional status using WHO-recommended Z-scores, and assessing cognitive performance through continuous assessment tests. The parasites were identified by their morphology with reference to the Cheesbrough parasitological manual. Statistical analysis was performed using chi-square tests and Quantitative Parasitological Software version 3.0. The results showed a prevalence rate of 46.4% for intestinal parasites, with Ascaris lumbricoides being the most common (50.5%). The association between intestinal parasites and cognitive performance was significant in students infected with &lt;em&gt;Ascaris lumbricoides&lt;/em&gt; (50.2), hookworm (52.5), &lt;em&gt;Hymenolepis nana&lt;/em&gt; (45.5) and co-infection with Ascaris hookworm (41.2) who had extremely low IQs. Assessment of nutritional status revealed that 21.2% of students were malnourished, and assessment of cognitive performance revealed a significant association between age (&lt;em&gt;P&lt;/em&gt; = 0.00164) and gender (&lt;em&gt;P&lt;/em&gt; = 0.000891) with IQ categories. Among the age groups, 16–18 year olds had the highest scores at 41.18% and fell under ∖“Extremely Low IQ∖”, the age group &gt; 19 was below ∖“Borderline∖” at 50%, a higher percentage of men were under ∖\" “Borderline IQ” (47.27%), while a larger proportion of women were classified as “extremely low” (29.91%). The students' eating habits showed that 75.5% reported regular daily food consumption, while 24.5% had irregular eating habits. Most students (67.5%) had normal nutritional status (−2 ≤ Z ≤+1), with males (65%) slightly outnumbering females (35%), and the highest prevalence among 16–18-year-olds (36%). Overweight students (+1 &lt; Z ≤ +2) comprised 15%, with a similar prevalence among males (22%) and females (15%), and the highest prevalence also in the 16–18-year age group (36%). The relationship between dietary habits and cognitive performance revealed that regular meals per day had a statistically significant association with cognitive performance (&lt;em&gt;P&lt;/em&gt; = 0.007), frequency of consumption of fruits (&lt;em&gt;P&lt;/em&gt; = 0.0378), fried foods (&lt;em&gt;P&lt;/em&gt; = 0.028) and of daily water intake (&lt;em&gt;P&lt;/em&gt; = 0.005) also showed significant relationships with cognitive output. These results provide valuable insights into the health and well-being of secondary school students in southeastern Nigeria ","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 200-216"},"PeriodicalIF":0.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143874104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between dietary fiber, the gut microbiota, and health outcomes in breast cancer survivors: A scoping review 膳食纤维、肠道微生物群与乳腺癌幸存者健康结局之间的关系:一项范围综述
Clinical Nutrition Open Science Pub Date : 2025-04-16 DOI: 10.1016/j.nutos.2025.03.012
Elham Samami , Angela Starkweather , Debra E. Lyon , Debra L. Kelly
{"title":"Associations between dietary fiber, the gut microbiota, and health outcomes in breast cancer survivors: A scoping review","authors":"Elham Samami ,&nbsp;Angela Starkweather ,&nbsp;Debra E. Lyon ,&nbsp;Debra L. Kelly","doi":"10.1016/j.nutos.2025.03.012","DOIUrl":"10.1016/j.nutos.2025.03.012","url":null,"abstract":"<div><h3>Background</h3><div>Breast cancer (BC) is the most frequently identified malignancy in women and a major cause of female mortality. Its progression is influenced by a range of factors, including genetic, environmental, lifestyle, and hormonal elements. Recently, the gut microbiota (GM) has emerged as an important factor impacting BC. Dietary factors, particularly dietary fibers, may play a significant role in BC survivorship. These nondigestible carbohydrates serve as nutrients for gut microorganisms, promoting GM diversity and production of beneficial short-chain fatty acids (SCFAs), which possess anti-inflammatory and antiproliferative properties, influencing estrogen metabolism through the gut estrobolome, which modulates estrogen exposure and BC risk. This review synthesizes current literature on the effects of dietary fibers on GM in BC patients, exploring underlying mechanisms and clinical implications.</div></div><div><h3>Method</h3><div>Studies from PubMed/Medline and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases were identified up to June 2024, including quantitative designs targeting BC cases with performed GM analyses.</div></div><div><h3>Results</h3><div>Ten studies met the inclusion criteria, revealing that dietary fibers consistently correlate with beneficial changes in GM, such as increased diversity and beneficial bacterial abundance while reducing harmful bacteria linked to estrogen reabsorption. Dietary fibers influence GM by serving as fermentation substrates and producing SCFAs.</div></div><div><h3>Conclusions</h3><div>The review highlights the necessity of standardizing microbiota analysis and dietary assessment methods and calls for long-term studies across diverse populations. Personalized nutritional interventions based on individual GM microbiota hold promise to improve BC outcomes and quality of life.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 174-189"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143859256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The nutritional status of people hospitalized for hyperemesis gravidarum 妊娠剧吐住院患者的营养状况
Clinical Nutrition Open Science Pub Date : 2025-04-15 DOI: 10.1016/j.nutos.2025.03.009
Larissa A.W. Jansen , Lois M. van der Minnen , Joris A.M. van der Post , Joke M.J. Bais , Carrie Ris-Stalpers , Henk A. Bremer , David P. van der Ham , Wieteke M. Heidema , Anjoke Huisjes , Gunilla Kleiverda , Hinke M. Kruizenga , Simone M. Kuppens , Judith O.E.H. van Laar , Josje Langenveld , Flip van der Made , Dimitri Papatsonis , Marie-José Pelinck , Paula J. Pernet , Leonie van Rheenen-Flach , Robbert J. Rijnders , Rebecca C. Painter
{"title":"The nutritional status of people hospitalized for hyperemesis gravidarum","authors":"Larissa A.W. Jansen ,&nbsp;Lois M. van der Minnen ,&nbsp;Joris A.M. van der Post ,&nbsp;Joke M.J. Bais ,&nbsp;Carrie Ris-Stalpers ,&nbsp;Henk A. Bremer ,&nbsp;David P. van der Ham ,&nbsp;Wieteke M. Heidema ,&nbsp;Anjoke Huisjes ,&nbsp;Gunilla Kleiverda ,&nbsp;Hinke M. Kruizenga ,&nbsp;Simone M. Kuppens ,&nbsp;Judith O.E.H. van Laar ,&nbsp;Josje Langenveld ,&nbsp;Flip van der Made ,&nbsp;Dimitri Papatsonis ,&nbsp;Marie-José Pelinck ,&nbsp;Paula J. Pernet ,&nbsp;Leonie van Rheenen-Flach ,&nbsp;Robbert J. Rijnders ,&nbsp;Rebecca C. Painter","doi":"10.1016/j.nutos.2025.03.009","DOIUrl":"10.1016/j.nutos.2025.03.009","url":null,"abstract":"<div><h3>Background and aims</h3><div>Hyperemesis gravidarum (HG) is defined as severe nausea and vomiting in pregnancy. Persistent nausea and vomiting can lead to weight loss and depletion of maternal nutrients. The severity and persistence of maternal undernutrition secondary to HG, as expressed by energy, macro- and micronutrient intake, has not been extensively studied. The aim of our study was to prospectively investigate the nutritional intake of people with HG during the first twenty weeks of their pregnancy.</div></div><div><h3>Methods</h3><div>For this study, we included people admitted for HG, who participated in the Maternal and Offspring outcomes after Treatment of HyperEmesis by Refeeding randomized controlled trial (MOTHER RCT, NTR 4197). Individuals who refused randomization were studied in an observational cohort study. We included pregnant people between 5 and 20 weeks of gestation who had completed at least one dietary questionnaire from 19 hospitals in the Netherlands. This questionnaire was collected weekly, until 20 weeks of gestation or until symptoms abated, and registered symptom severity, maternal weight and dietary intake. We excluded participants who only had data available while on tube feeding, or within 2 days of tube cessation. A 24-hour intake was calculated for intake of energy, protein, carbohydrates, fat, saturated fat, iodine, iron, folate, omega3 fatty acids and thiamine.</div></div><div><h3>Results</h3><div>Between 2013–2016, we collected 601 dietary questionnaires from 160 participants (varying between 1 to 12 per person). The daily intake of energy, protein, carbohydrates and fat was sufficient (more than 75% of recommended amount) in respectively 27%, 38%, 73% and 27% of dietary questionnaires. The daily intake of energy, protein, carbohydrates and fat was less than 50% of the recommended amount in respectively 44%, 39%, 17% and 43% of dietary questionnaires. 23% of dietary questionnaires exceeded the maximum recommended amount of saturated fat a day. For iodine and iron daily intake was sufficient in respectively 11% and 14% of dietary questionnaires. The daily intake of iodine and iron did not reach 50% of recommended amount in respectively 67% and 64%. Only three dietary questionnaires showed a sufficient intake of folate, 93% of dietary questionnaires did not reach 50% of recommended amount of folate. For omega3 fatty acids and thiamine the daily intake was sufficient in respectively 78% and 25%. The daily intake of omega 3 fatty acids and thiamine was less than 50% of the recommended amount in respectively 17% and 53%.</div></div><div><h3>Conclusion</h3><div>Our findings demonstrate that intake of macro-and micronutrients as well as total energy intake is deficient in people who suffer from HG. This is a particular concern, as nutrient deficiency in pregnancy can negatively impact the health of the offspring.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 253-270"},"PeriodicalIF":0.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143906122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Scientific basis of dietary inflammatory index (DII): A dietary tool to metabolic syndrome risk 饮食炎症指数(DII)的科学依据:代谢综合征风险的饮食工具
Clinical Nutrition Open Science Pub Date : 2025-04-14 DOI: 10.1016/j.nutos.2025.04.002
Falak Zeb , Tareq Osaili , Huma Naqeeb , MoezAllslam Ezzat Faris , Leila Cheikh Ismail , Reyad Shakir Obaid , Farah Naja , Hadia Radwan , Hayder Hasan , Mona Hashim , Dimitrios Papandreou , Ioannis Savvaidis , Sharifa AlBlooshi , Iftikhar Alam
{"title":"Scientific basis of dietary inflammatory index (DII): A dietary tool to metabolic syndrome risk","authors":"Falak Zeb ,&nbsp;Tareq Osaili ,&nbsp;Huma Naqeeb ,&nbsp;MoezAllslam Ezzat Faris ,&nbsp;Leila Cheikh Ismail ,&nbsp;Reyad Shakir Obaid ,&nbsp;Farah Naja ,&nbsp;Hadia Radwan ,&nbsp;Hayder Hasan ,&nbsp;Mona Hashim ,&nbsp;Dimitrios Papandreou ,&nbsp;Ioannis Savvaidis ,&nbsp;Sharifa AlBlooshi ,&nbsp;Iftikhar Alam","doi":"10.1016/j.nutos.2025.04.002","DOIUrl":"10.1016/j.nutos.2025.04.002","url":null,"abstract":"<div><h3>Background and Aims</h3><div>The dietary inflammatory index (DII) is a tool that quantifies the inflammatory potential of an individual's diet, offering a scientific basis for personalized nutrition. The DII scores of foods and nutrients are based on their pro- or anti-inflammatory potential. DII is associated with metabolic diseases and health status but the results are inconsistent. Therefore this review was conducted to highlight the scientific basis of DII and its association with metabolic diseases.</div></div><div><h3>Methods</h3><div>We conducted independent literature research for this review between January 2006 and January 2025 utilizing scholarly databases such as PubMed, ScienceDirect, Google Scholar, and Web of Science.</div></div><div><h3>Results</h3><div>This review highlights the scientific basis of DII, focusing on its ability to capture the complex interactions between dietary patterns and health outcomes in various inflammatory and metabolic diseases. Moreover, the current review discusses the modification and interpretation of multiple types of DII over time. By calculating an individual's DII score, healthcare professionals can identify pro-inflammatory dietary patterns that may exacerbate chronic diseases with an inflammatory predisposing background, such as obesity, cardiovascular disease, diabetes, and cancer. This review also highlight the association of DII score with various inflammation-associated diseases and strengthen nutrition guidelines to promote anti-inflammatory dietary patterns.</div></div><div><h3>Conclusion</h3><div>The DII offers a valuable tool for healthcare professionals to integrate nutrition into patient care, promoting a more comprehensive disease prevention approach. Further research and validation will continue to refine and optimize the DII, enhancing its potential to transform the practices of clinical nutrition and improve patient outcomes.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 138-161"},"PeriodicalIF":0.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143859255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is the acid load of the diet related to esophageal cancer? A case-control study 饮食中的酸负荷与食管癌有关吗?病例对照研究
Clinical Nutrition Open Science Pub Date : 2025-04-08 DOI: 10.1016/j.nutos.2025.03.011
Omid Nikpayam , Parmis Mirzaei , Golbon Sohrab , Amirmahdi Najfi , Reza Eghdam Zamiri , Alireza Ostadrahimi
{"title":"Is the acid load of the diet related to esophageal cancer? A case-control study","authors":"Omid Nikpayam ,&nbsp;Parmis Mirzaei ,&nbsp;Golbon Sohrab ,&nbsp;Amirmahdi Najfi ,&nbsp;Reza Eghdam Zamiri ,&nbsp;Alireza Ostadrahimi","doi":"10.1016/j.nutos.2025.03.011","DOIUrl":"10.1016/j.nutos.2025.03.011","url":null,"abstract":"<div><h3>Background</h3><div>Esophageal adenocarcinoma (EAC) is a prevalent type of cancer both globallyand in the northern regions of Iran. The relationship between dietary acid load (DAL) and EAC is not well established. Therefore, a study was conducted to investigate the association between DAL and EAC.</div></div><div><h3>Methods</h3><div>This case-control study involved 120 individuals with EAC as the case group and 240 individuals without a history of malignancy as the control group. Dietary intake was assessed using a valid food frequency questionnaire (FFQ), and the dietary acid load (DAL) was calculated using a valid formula. The association between DAL and EAC was evaluated using multivariate logistic regression analysis.</div></div><div><h3>Results</h3><div>The results of the current study indicate that, after adjusting for potential confounding factors, individuals with a higher potential renal acid load (PRAL) score in their diet have an elevated risk of developing EAC (OR: 2.3; 95%CI: 4.41–1.11; p:0.03). In contrast, there was no significant association between the net endogenous acid production (NEAP) index score and the risk of EAC (OR: 1.76; 95%CI: 0.9–3.24; p: 0.07).</div></div><div><h3>Conclusion</h3><div>The findings of the current study show that DAL has a direct and significant relationship with the risk of EAC.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 190-199"},"PeriodicalIF":0.0,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143870471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing enteral nutrition care: Innovating and validating a communication tool for healthcare networks 加强肠内营养护理:创新和验证医疗保健网络的通信工具
Clinical Nutrition Open Science Pub Date : 2025-04-07 DOI: 10.1016/j.nutos.2025.04.001
Kelly Cristina Uniat, Caroline Opolski Medeiros, Maria Eliana Madalozzo Schieferdecker
{"title":"Enhancing enteral nutrition care: Innovating and validating a communication tool for healthcare networks","authors":"Kelly Cristina Uniat,&nbsp;Caroline Opolski Medeiros,&nbsp;Maria Eliana Madalozzo Schieferdecker","doi":"10.1016/j.nutos.2025.04.001","DOIUrl":"10.1016/j.nutos.2025.04.001","url":null,"abstract":"<div><h3>Background &amp; Aims</h3><div>The implementation of instruments for monitoring Enteral Nutrition is important for the continuity of treatment. The objective of this study was to develop and validate an instrument for communication between nutritionists at different points of care for enteral nutrition patients.</div></div><div><h3>Methods</h3><div>Double Diamond Co-Design Study. It was divided into the following steps: instrument development, applicability analysis, and content validation. Initially, bibliographic research of national and international technical documents was carried out to create the items. For applicability analysis, the instrument was operated by nutrition residents of primary, hospital, and clinical care. In content validation, the Content Validity Index (CVI) was analyzed by items and complete instruments, concerning the criteria: relevance and clarity. CVI score values equal to or greater than 0.80 were considered for clarity and relevance equal to or greater than 0.90.</div></div><div><h3>Results</h3><div>In the first step, the instrument presented 60 items and 7 categories. In the second step, with suggestions for modifications, 53 items and 7 categories remained. In the content validation, 23 nutritionists from Brazil participated, the Content Validity Index of the complete instrument showed clarity (0.932) and relevance (0.988) with scores above the established standards.</div></div><div><h3>Conclusion</h3><div>The validated instrument is considered clear, relevant, unprecedented, and low-cost, and can be used for the continuity of care for enteral nutrition patients at any point in the health network.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 162-173"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143859258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutritional support practices among intensive care unit (ICU) patients, observational study 重症监护病房(ICU)患者的营养支持实践,观察性研究
Clinical Nutrition Open Science Pub Date : 2025-04-05 DOI: 10.1016/j.nutos.2025.03.010
May Hamdan , Fatima Al-Amouri , Ayat Ali Abu-fara , Mai Qasem Heih , Fatima Ibrahim Manasrah , Hanan Alaa Abu-shamsyh , Manal Badrasawi
{"title":"Nutritional support practices among intensive care unit (ICU) patients, observational study","authors":"May Hamdan ,&nbsp;Fatima Al-Amouri ,&nbsp;Ayat Ali Abu-fara ,&nbsp;Mai Qasem Heih ,&nbsp;Fatima Ibrahim Manasrah ,&nbsp;Hanan Alaa Abu-shamsyh ,&nbsp;Manal Badrasawi","doi":"10.1016/j.nutos.2025.03.010","DOIUrl":"10.1016/j.nutos.2025.03.010","url":null,"abstract":"<div><h3>Background and Aims</h3><div>Critically ill patients are at high risk of mortality, morbidity, and poor outcomes. Therefore, nutritional support is the standard care to avoid related complications and improve health outcomes. The aim of this study is to identify feeding practices among ICU patients, evaluate their nutritional adequacy, and assess the prevalence of malnutrition and its associated factors.</div></div><div><h3>Methods</h3><div>This observational study involved 106 ICU patients in three hospitals at Hebron/Palestine. An interview-based questionnaire was used to collect data related to sociodemographic, lifestyle, ICU-related data, medical history, clinical outcomes, physical examination, energy, and protein consumption. Malnutrition was evaluated using the malnutrition universal screening tool (MUST), and biochemical data were recruited from patients' medical records.</div></div><div><h3>Results</h3><div>Among study participants aged 18–99 years (63.69 ± 20.48), enteral feeding was the predominant route among 51.9 %, and nutritional support was initiated two days after ICU admission. In addition, 91.5 % and 67 % of patients failed to receive their nutritional requirements of energy and protein, respectively. The malnutrition universal screening tool revealed that 53.8 % of ICU patients were at low risk of malnutrition, 20.8 % were at medium risk, and 25.5 % were at high risk of malnutrition, while lower energy consumption contributed significantly to the higher risk of malnutrition among ICU patients.</div></div><div><h3>Conclusion</h3><div>The study found that enteral feeding is the main nutritional support in ICU patients, but energy and protein intake are insufficient. Despite early feeding, malnutrition rates are high and linked to lower calorie intake, emphasizing the need for better nutritional screening and interventions to improve patient outcomes.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 129-137"},"PeriodicalIF":0.0,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143859257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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