Clinical Nutrition Open Science最新文献

{"title":"The predictive power of postoperative complications and the agreement between PG-SGA SF and GLIM in identifying malnourishment in patients with pancreatic diseases before pancreatic surgery","authors":"Martina Petrolo ,&nbsp;Mia Solholt Godthaab Brath ,&nbsp;Randi Tobberup ,&nbsp;Sofie Ehlers ,&nbsp;Marie Njerve Olsen ,&nbsp;Elena Rangelova ,&nbsp;Lars Ellegård ,&nbsp;Folke Hammarqvist ,&nbsp;Henrik Højgaard Rasmussen","doi":"10.1016/j.nutos.2025.03.005","DOIUrl":"10.1016/j.nutos.2025.03.005","url":null,"abstract":"<div><h3>Background</h3><div>Patients with pancreatic diseases impose several nutritional challenges and identifying malnourished patients is important since malnutrition may increase the risk of postoperative complications.</div></div><div><h3>Aims</h3><div>To assess the agreement between Patient Generated-Subjective Global Assessment Short Form (PG-SGA SF) and Global Leadership Initiative on Malnutrition (GLIM) criteria in identifying malnutrition in patients with pancreatic diseases scheduled for elective surgery. To investigate whether there is an association between malnutrition and postoperative complications.</div></div><div><h3>Methods</h3><div>A secondary analysis of a prospective observational cross-sectional study in patients with pancreatic diseases undergoing pancreatic surgery from September 2017 to January 2018 at Karolinska University Hospital (Stockholm, Sweden). Nutritional screening was performed by PG-SGA SF and malnutrition diagnosis was defined by GLIM with and without prior screening.</div></div><div><h3>Results</h3><div>A total of 34 patients were included (16 men, 18 women), median age 70 (range 38–83) years, median BMI 24.4 (range 19.3–40.4) kg/m². Risk of malnutrition was detected in 14 patients (41 %) by PG-SGA SF. Malnutrition was detected in 9 patients (26 %) by GLIM with prior screening (GLIM + screening) and in 17 patients (50 %) by GLIM without prior screening (GLIM - screening). The agreement between PG-SGA SF and GLIM - screening was 62 %, the sensitivity 64 %, the specificity 60 %, and the Cohen's kappa was 0.235, <em>P</em>=0.08. GLIM - screening had a positive predictive value of 53 % and negative predictive value of 71 %. A total of 14 patients had postoperative complications. The GLIM - screening showed a RR of 1.40 (CI: 0.58–3.37) of postoperative complications when being malnourished. The GLIM + screening showed a RR of 1.66 (CI: 0.49–5.61) of postoperative complications when being malnourished.</div></div><div><h3>Conclusions</h3><div>This study showed that PG-SGA SF and GLIM had a slight to fair agreement in detecting malnutrition in patients undergoing pancreatic resection. No firm conclusions in predicting postoperative complications could be found.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 96-107"},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143738247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early versus delayed enteral nutrition in critically ill children under 12 years of age: A systematic review and meta-analysis of randomised controlled trials","authors":"Marianne E. Visser ,&nbsp;Roselyn Chipojola ,&nbsp;Sarah Gordon ,&nbsp;Amanda Brand ,&nbsp;Nyanyiwe Mbeye ,&nbsp;Gertrude Kunje ,&nbsp;Talitha Mpando ,&nbsp;Suzgika Lakudzala ,&nbsp;Elodie Besnier ,&nbsp;Celeste E. Naude","doi":"10.1016/j.nutos.2025.03.004","DOIUrl":"10.1016/j.nutos.2025.03.004","url":null,"abstract":"<div><h3>Background &amp; aims</h3><div>Enteral nutrition (EN) is key to reducing malnutrition risk in critically ill children, with timing of EN initiation being an important consideration. This systematic review aimed to assess the effects of early enteral nutrition (EEN) compared to delayed enteral nutrition (DEN) in critically ill children as part of the Global Evidence, Local Adaptation (GELA) project.</div></div><div><h3>Methods</h3><div>We searched PubMed, Embase and two trial registries (January 2000–November 2023) and included randomised controlled trials (RCTs) comparing EEN (typically within 24–48 hours of admission) to DEN (typically &gt;48 hours of admission) in children aged one month to 12 years, and excluding studies in children with severe acute malnutrition, or conditions requiring long-term EN. Guided by Cochrane methods, we conducted random-effects meta-analyses to obtain pooled effect estimates for outcomes selected by the guideline development group, assessed risk of bias using Cochrane's Risk-of-Bias-2 tool and assessed certainty of the evidence using Grading of Recommendations, Assessment, Development and Evaluation (GRADE).</div></div><div><h3>Results</h3><div>Four RCTs randomising 899 children in critical care settings in India, Iran and USA were included. Overall risk of bias was assessed as ‘high risk’ or ‘some concerns’ for all outcomes. Low-certainty evidence suggests that EEN may reduce in-hospital mortality (absolute effect (AE) 53 fewer deaths per 1000, 95% CI -85 to -12, I²=0%, 3 RCTs, n=869) and length of hospital stay on average (mean difference (MD) -2.98 days, 95% CI -9.79 to 3.83, I²=0%, 2 RCTs, n=760) compared to DEN, and may result in little to no difference in nosocomial infections (wound and blood stream infections) (AE 5 fewer cases per 1000, 95% CI -52 to 52, I²=0%, 3 RCTs, n=869). Evidence is very uncertain about effects on length of paediatric intensive care unit stay, number of days on the ventilator, sepsis, ventilator-associated pneumonia, and time to wound healing.</div></div><div><h3>Conclusion</h3><div>EEN may reduce in-hospital mortality and length of hospital stay in critically ill children, but our confidence in the effect estimates is limited. More high-quality studies comparing EEN to DEN in relation to patient-relevant and clinically important outcomes in paediatric critical illness are needed.</div></div><div><h3>Prospective registration</h3><div>PROSPERO CRD42023487325.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 108-128"},"PeriodicalIF":0.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143746668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interruptions in administration of enteral feeding and automatic compensation: A post hoc analysis of the smART+ study","authors":"I. Kagan ,&nbsp;E. Robinson ,&nbsp;M. Hellerman Itshaki ,&nbsp;P. Singer","doi":"10.1016/j.nutos.2025.03.008","DOIUrl":"10.1016/j.nutos.2025.03.008","url":null,"abstract":"<div><h3>Rationale</h3><div>Multiple obstacles exist to achieve enteral feeding targets defined as patient-related (PR) or diagnostic/therapeutic related (DTR) interruptions. A new technology was developed to adapt and compensate enteral feeding according to gastric tolerance as well as DTR interruptions (1). In this post hoc analysis we evaluated PR or DTR interruptions as well as the compensation achieved by the platform.</div></div><div><h3>Methods</h3><div>The compensation related to PR or DTR was analyzed in 50 patients from the study group (1). A computerized analysis detected all the PR and DTR interruptions. Analysis used only those days with at least 12 hours of active system. Compensation was programmed to provide 100 % of the missing nutrition related to DTR interruptions and 50 % of the measured gastric active residual release (ARR).</div></div><div><h3>Results</h3><div>280 days were obtained with at least 12 hours of recording from the 313 hospitalization days. Interruptions occurred during 4.5 hours in mean. A total median of 75 min (19.5 % of the interruption time) was related to PR and a total median of 196 min (80.5 %) to DTR interruptions. However, the feeding efficacy remained very high (89,3 %) during the study period. Nutritional therapy close to 100 % of the target was obtained in 176 days out of the 280 investigated days.</div></div><div><h3>Conclusion</h3><div>Interruptions of enteral feeding were mainly related to DTR interventions, but the platform was able to fully compensate for them. The PR interruptions were only partially compensated. The smart + platform provides an effective tool to recognize feeding interruptions and to compensate them.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 62-69"},"PeriodicalIF":0.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Redefining reimbursement policies: A novel value framework for medical nutrition","authors":"Mohamed Nasser Farghaly ,&nbsp;Sara Al Dallal ,&nbsp;Katrina Hassan ,&nbsp;Sherif Adel Mahmoud ,&nbsp;Wafaa Ayesh ,&nbsp;Ahmed Maged Abdelmawla ,&nbsp;Magriet Raxworthy ,&nbsp;Sangam Mahagaonkar","doi":"10.1016/j.nutos.2025.03.007","DOIUrl":"10.1016/j.nutos.2025.03.007","url":null,"abstract":"<div><div>This study aims to review the medical nutrition reimbursement policies in Dubai to facilitate refining of the mandate for inclusion and insurance coverage of nutritional supplementation for specific disease conditions. This study was conducted in two phases, which included a targeted literature review to collect evidence on the use of medical nutrition in target populations (cancer patients, pediatric patients with food and cow milk protein allergy [CMPA], disease-related malnutrition [DRM], and epilepsy) in phase 1 and discussion among the experts from United Arab Emirates [UAE] to review and validate the findings from the literature review and discuss the readiness of Dubai Health Authority (DHA) sector in phase 2 for reimbursement of medical nutrition interventions. Currently, reimbursement for medical nutrition intervention in the private sector is provided on a case-by-case basis in Dubai. Based on the outcomes of pilot projects, the experts agreed to change the mandate for oncology patients and pediatric patients with CMPA. For epilepsy patients, experts advocated the necessity of defined guidelines and recommended the analysis of claims data and establishment of a task force. Effectively formulating guidelines on the use of medical nutrition and using cost-effectiveness models are required to encourage payers to invest in medical nutrition.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 82-95"},"PeriodicalIF":0.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143705214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of changes in the texture level of consumed food with nutritional and functional outcomes among older patients undergoing rehabilitation","authors":"Yukiko Sawa","doi":"10.1016/j.nutos.2025.03.006","DOIUrl":"10.1016/j.nutos.2025.03.006","url":null,"abstract":"<div><h3>Background &amp; aims</h3><div>Dysphagia is common in older patients, and texture-modified diets are used in its clinical management. However, texture-modified diets can cause malnutrition or poor functional recovery. This study aimed to examine the relationship of changes in the food texture level with nutritional improvement and functional recovery in older patients undergoing rehabilitation.</div></div><div><h3>Methods</h3><div>This single-center cross-sectional study included patients aged ≥65 years undergoing rehabilitation and on oral intake (International Dysphagia Diet Standardization Initiative framework level 3–6). We evaluated nutritional status using the Mini Nutritional Assessment Short Form and ADLs using the Functional Independence Measure (FIM). Patients were categorized into two groups: those with increased food texture levels were allocated to the increased food texture level (IF) group, and those with no texture level change or decreased level were assigned to the non-increased food texture level (NIF) group. The discharge outcomes were compared between the groups. Multivariate analyses were performed to determine the association between changes in the food texture level and nutritional improvement, FIM gain, and discharge to home.</div></div><div><h3>Results</h3><div>Among 203 patients (mean age, 86 years; 115 women), 57 (28.1%) and 146 (74.9%) patients were assigned to the IF and NIF groups, respectively. The IF group showed greater nutritional improvement (89.5% vs. 61.6%), greater FIM gain (median, 23 vs. 7.5), and a higher proportion of home discharges (64.9% vs. 39.7%) than did the NIF group. Multivariate analyses showed that an increase in the texture level of the consumed food was independently associated with nutritional improvement (odds ratio [OR] = 3.05, 95% confidence interval [CI] = 1.07 to 8.65) and FIM gain (partial regression coefficient [B] = 10.65, 95% CI = 6.19 to 15.11). The IF group had higher odds of home discharge (OR = 1.94, 95% CI = 0.92 to 4.11).</div></div><div><h3>Conclusions</h3><div>An increase in the texture level of consumed food may be associated with nutritional improvement, ADL recovery, and discharge to home.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 44-53"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimation of body weight from selected body circumferences in the hospital setting","authors":"M.J.V. Parasvita ,&nbsp;V. Wijaya ,&nbsp;N. Budiman ,&nbsp;L. Wibowo ,&nbsp;W. Lukito","doi":"10.1016/j.nutos.2025.03.003","DOIUrl":"10.1016/j.nutos.2025.03.003","url":null,"abstract":"<div><h3>Background and Aims</h3><div>In hospital settings, body weight (BW) measurement can only sometimes be done, even though it is indispensable to justify nutritional and pharmacologic interventions. To be able to monitor the BW and define the dynamic of hospital malnutrition, it is pertinent to pursue an estimate of BW using the accessible body circumferences (BCs) variables, as described in the current study.</div></div><div><h3>Methods</h3><div>Four hundred seventy-seven patients (aged 17–76) were recruited. Only those who could stand up for measuring direct body weight (BW), height (H), and selected BCs were eligible for the study. Thirty-seven patients were excluded from the statistical analyses: 18 with significant edema, 16 with BW &gt; 110 kg (considered outliers), and three without BW data. A total of 440 patients (155 men and 285 women) were included in the final analyses. BW was measured using bioelectrical impedance SECA type 514, and BCs, namely mid-upper arm circumference (MUAC), abdominal circumference (AC), and calf circumference (CC), were measured using a SECA 201 non-elastic tape (SECA 201). We used hierarchical analyses to estimate BW (eBW) with gender and the existence of disease as control variables and BCs as predicted variables.</div></div><div><h3>Results</h3><div>After controlling for gender and disease, the regression model could predict 94.1% of BW variability (R²= 0.942) using a combination of 3 BCs as predicted variables, 89.0–93.3% (R²=0.891–0.933) of BW variability using a combination of 2 BCs; and 81.2–84.6% of BW variability (R² = 0.814–0.847) with single BC as predicted variables.</div></div><div><h3>Conclusions</h3><div>The best-fit model to estimate patients' BW used a combination of 3 BCs as predicted variables. Nevertheless, other models with the predictability of BW variability of at least 80% could be considered alternatives in developing countries and Asian people with diverse hospital capacities. Further study is needed to validate these BW prediction formulas in clinical practices and describe their variations against the actual BW values.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 70-81"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143705215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of interventions to improve breastfeeding outcomes among women from vulnerable ethnic groups: Protocol for a systematic review and meta-analysis","authors":"Paula Eugenia Barral ,&nbsp;Ana Veronica Scotta ,&nbsp;María Gema Cid Expósito ,&nbsp;Agustín Ramiro Miranda","doi":"10.1016/j.nutos.2025.03.002","DOIUrl":"10.1016/j.nutos.2025.03.002","url":null,"abstract":"<div><div>Despite the known benefits of breastfeeding (BF) on maternal and child health and environmental and economic levels, global BF rates are lower than recommended, especially in vulnerable ethnic groups. This review protocol is designed to analyze the interventions to promote BF in women from vulnerable ethnic groups considering the initiation, duration, and exclusivity of the practice.</div><div>The systematic review will adhere to the PRISMA guidelines. Searches will be conducted in March 2025 across eleven databases. Randomized controlled trials will be included, without language or year restrictions. The quality of the included studies will be assessed using the JBI Critical Appraisal Tool. Data will be extracted and synthesized systematically, considering a Social-Ecological Model and the Breastfeeding Gear Model. The meta-analysis will be carried out according to the Cochrane handbook for systematic reviews of interventions.</div><div>A multilevel perspective is essential for effectively implementing evidence-based BF support, particularly when considering vulnerable ethnic groups. This work will summarize the interventions to overcome barriers in the promotion of BF. Therefore, the findings of this review will integrate models in line with the Social Determinants of Health and the sustainable development goals.</div><div>PROSPERO: CRD42024529223.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 54-61"},"PeriodicalIF":0.0,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overweight and obesity combined with low physical function and non-communicable diseases among older adults in nursing homes represent a group with nutritional risk, malnutrition, and sarcopenia – A cross-sectional pilot study","authors":"Tenna Christoffersen ,&nbsp;Inge Tetens ,&nbsp;Anja Weirsøe Dynesen ,&nbsp;Margit Dall Aaslyng ,&nbsp;Janne Kunchel Lorenzen ,&nbsp;Anne Marie Beck","doi":"10.1016/j.nutos.2025.03.001","DOIUrl":"10.1016/j.nutos.2025.03.001","url":null,"abstract":"<div><h3>Background &amp; Aims</h3><div>Older adults with overweight and obesity (overnutrition) may be overlooked in terms of nutritional risk. The aim of the present study was to characterise older adults in community care with overnutrition according to a proposed screening model and to compare this group with older adults with normal weight in terms of nutritional risk, malnutrition, sarcopenia, or a combination of both.</div></div><div><h3>Methods</h3><div>This cross-sectional pilot study included residents from six nursing homes in a rural Danish municipality. From April to July 2022, we collected data on age, sex, body composition, chronic diseases, muscle strength, nutritional risk and dietary intake from medical records. Nutritional risk, malnutrition and sarcopenia assessments were based on the criteria set in the Eating Validation Scheme, the Global Leadership Initiative on Malnutrition and the European Working Group on Sarcopenia in Older People. A covariate analysis and a Fisher's exact test were used to evaluate differences in the variables and in nutritional risk, malnutrition and sarcopenia between the groups.</div></div><div><h3>Results</h3><div>A total of 116 residents were included in the study. We found that 52% had overnutrition and that 89% of these older adults experienced both low physical function and non-communicable diseases. Compared with older adults with normal weight, the group with overnutrition had a lower calf circumference adjusted for body mass index (<em>P</em>=0.008), a lower 30 second Chair Stand Test score (<em>P</em>=0.03), a higher prevalence of sarcopenia (<em>P</em>=0.02) and a statistically non-significant higher prevalence of malnutrition and sarcopenia combined (<em>P</em>=0.0002).</div></div><div><h3>Conclusion</h3><div>More than half of the older nursing home residents in this study had overnutrition, with almost 90% experiencing both NCDs and low physical function. When comparing the group with overnutrition with older adults with normal weight, the study showed that they had a similar prevalence of nutritional risk and malnutrition and that the prevalence of sarcopenia was higher in those with overnutrition.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"61 ","pages":"Pages 14-25"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143628446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proposal of a tool for screening the risk of cachexia in cancer patients","authors":"Thais Manfrinato Miola ,&nbsp;Liane Brescovici Nunes de Matos ,&nbsp;Susana da Rocha Dias","doi":"10.1016/j.nutos.2025.02.012","DOIUrl":"10.1016/j.nutos.2025.02.012","url":null,"abstract":"<div><h3>Background and Objectives</h3><div>Cancer cachexia is a multifaceted syndrome comprised of fatigue; progressive loss of functional capacity; increased risks of chemotherapeutic drug toxicity, postoperative complications, and hospitalization; decreased quality of life; and reduced survival. The objective of this study was to develop a screening tool to identify the risk of cachexia in outpatients with cancer.</div></div><div><h3>Methods</h3><div>The tool was developed to detect the risk of cachexia in outpatients treated at an oncology center. The proposed screening tool was based on diagnostic criteria for cachexia; functionality; and symptoms that may reduce alimentation. The self-administered tool was also posted on the hospital website to enable access by health professionals from other hospitals and clinics, as well as by patients.</div></div><div><h3>Results</h3><div>Data were collected from 275 patients receiving outpatient care. The most prevalent diagnosis was breast cancer (26.2%). The prevalence of metastatic cancer in the total sample was 25.1%. Risk of cachexia was identified in 37.8% of patients. Death within 30 days occurred in 47.1% (41 of 87) patients treated in the emergency room and was significantly associated with the risk of cachexia (n=39; 57.4%) (<em>P</em>&lt;0.001). Age, female sex, and metastatic disease were associated with the risk of cachexia (<em>P</em>&lt;0.001, <em>P</em>=0.014, <em>P</em>&lt;0.001, respectively).</div></div><div><h3>Conclusion</h3><div>Cachexia is a prevalent and underdiagnosed condition among cancer patients. The development of screening tools is extremely important to facilitate the early detection of patients at risk, with the aim of initiating proactive interventions.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"60 ","pages":"Pages 286-293"},"PeriodicalIF":0.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143577710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional care for adult burn survivors during the rehabilitation phase","authors":"Alyaa M. Zagzoog","doi":"10.1016/j.nutos.2025.02.011","DOIUrl":"10.1016/j.nutos.2025.02.011","url":null,"abstract":"<div><h3>Background</h3><div>Innovations in medicine have increased the survival rate of patients with burn injuries. Adult burn survivors, however, need comprehensive care, which could promote their wellness after a burn injury. Proper nutritional care, inducing nutritional education provided by Registered Dietitians (RDs) plays a crucial role in improving the wellness of adult burn survivors in the acute and rehabilitation recovery phases. The nature of research in nutritional care during the rehabilitation phase, however, needs to be mapped to promote evidence-based practice. This review identified and mapped the nature of research in nutritional care for adult burn survivors during the rehabilitation phase.</div></div><div><h3>Methods</h3><div>A complete systematic search was conducted by one reviewer in conjunction with a medical librarian using the PubMed database. This review included all types of peer-reviewed publications, and the published dates and geographic locations were unlimited. Only articles involving adults with at least 20% of TBSA burn were included.</div></div><div><h3>Results</h3><div>Among 26 articles meeting the inclusion criteria, the identification and mapping of the included articles led to four key findings: the continuum of nutritional assessment and education, the effectiveness of specific nutrients on burn outcomes, the necessity of monitoring vitamin D levels, and the need of RDs as a member in a burn care team.</div></div><div><h3>Conclusions</h3><div>This review includes different study designs with broad published dates, locations, and sample size, and provides the needed identification and mapping of literature. Using more than one database and including more than one reviewer would increase the rigours of the methodology, therefore, the findings.</div></div>","PeriodicalId":36134,"journal":{"name":"Clinical Nutrition Open Science","volume":"60 ","pages":"Pages 294-310"},"PeriodicalIF":0.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143577709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}