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Journal of Herbs, Spices and Medicinal Plants最新文献

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Hormonal Regulatory Impacts of Tinospora cordifolia Leaf Extract and Its Loaded Phytoniosome on Mifepristone-Induced Polycystic Ovarian Syndrome (PCOS) Rats – In Vivo Studies 堇叶Tinospora叶提取物及其负载的植物体对米非司酮诱导的多囊卵巢综合征（PCOS）大鼠的激素调节作用——体内研究
Journal of Herbs, Spices and Medicinal Plants Pub Date : 2023-08-20 DOI: 10.1080/10496475.2023.2248050
S. Masilamani, Priya Chokkalingam, Meera B, R. Hari, M. P
{"title":"Hormonal Regulatory Impacts of Tinospora cordifolia Leaf Extract and Its Loaded Phytoniosome on Mifepristone-Induced Polycystic Ovarian Syndrome (PCOS) Rats – In Vivo Studies","authors":"S. Masilamani, Priya Chokkalingam, Meera B, R. Hari, M. P","doi":"10.1080/10496475.2023.2248050","DOIUrl":"https://doi.org/10.1080/10496475.2023.2248050","url":null,"abstract":"ABSTRACT The effects of ethanolic leaf extract of Tinospora cordifolia (ELETC) and its loaded phytoniosomes (nELETC) on altered hormonal levels in female polycystic ovarian syndrome (PCOS) rats induced by mifepristone were investigated. Mifepristone (4 mg kg−1 b.w.) was given daily to female rats for 8 days to develop PCOS, which was then detected by a protracted estrous cycle. The treatment regimen for the rats with PCOS consisted of 200 mg kg−1 b.w. of ELETC and nELETC administered orally every day for 28 days. Hormone tests showed that metformin acted as a favorable control. Results demonstrated that ELETC and nELETC may be used as therapeutic alternatives for treating PCOS to decrease complications of hyperinsulinemia, insulin resistance, and hyperandrogenism.","PeriodicalId":35803,"journal":{"name":"Journal of Herbs, Spices and Medicinal Plants","volume":"29 1","pages":"470 - 480"},"PeriodicalIF":0.0,"publicationDate":"2023-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45057571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethnobotanical Study Among Tribal Communities of Kalimpong, West Bengal 西孟加拉邦噶伦蓬部落社区的民族植物学研究
Journal of Herbs, Spices and Medicinal Plants Pub Date : 2023-08-20 DOI: 10.1080/10496475.2023.2248910
L. Kandari, V. Bisht, T. Negi, R. Maikhuri, Satyan Chettri
{"title":"Ethnobotanical Study Among Tribal Communities of Kalimpong, West Bengal","authors":"L. Kandari, V. Bisht, T. Negi, R. Maikhuri, Satyan Chettri","doi":"10.1080/10496475.2023.2248910","DOIUrl":"https://doi.org/10.1080/10496475.2023.2248910","url":null,"abstract":"","PeriodicalId":35803,"journal":{"name":"Journal of Herbs, Spices and Medicinal Plants","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83901445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utilization of Traditional Medicinal Plants by Bidayuh Communities in Sarawak, Malaysia 马来西亚沙捞越Bidayuh社区对传统药用植物的利用
Journal of Herbs, Spices and Medicinal Plants Pub Date : 2023-07-03 DOI: 10.1080/10496475.2022.2140739
Vivian Patrick, T. Noweg, J. Nelson
{"title":"Utilization of Traditional Medicinal Plants by Bidayuh Communities in Sarawak, Malaysia","authors":"Vivian Patrick, T. Noweg, J. Nelson","doi":"10.1080/10496475.2022.2140739","DOIUrl":"https://doi.org/10.1080/10496475.2022.2140739","url":null,"abstract":"ABSTRACT This study was undertaken in Bidayuh communities in the Padawan, Bau, and Siburan districts in Malaysia to (1) compare the medicinal plant utilization, (2) compare the number of medicinal plants collected annually and total number of medicinal plant species collected, and (3) assess the influence of key socio-demographic factors on the pattern of annual collection and preferred species. Surveys were conducted on 226 households, based on stratified random sampling. Key informant in-depth investigation and group meetings were used to gather further information. A total of 44 medicinal plant species that were used to treat 25 ailments were recorded from all districts. Five primary ailments for which the plants were used were fever (11 plant species), wound (10 plant species), post-partum care (eight plant species), hypertension (seven plant species), and diseases of the skin (seven plant species). There was a difference in the number of medicinal plants collected annually (X 2(2) = 8.55, p = .01) with the highest mean difference between Kuching (Mean rank = 125.65) and Siburan (Mean rank = 97.78) districts. There was a difference in total medicinal plant species collected among household heads due to education levels (X 2(5) = 21.87, p = .00) with the highest mean difference between primary school (Mean rank = 138.07) and college (Mean rank = 69.00) education.","PeriodicalId":35803,"journal":{"name":"Journal of Herbs, Spices and Medicinal Plants","volume":"29 1","pages":"250 - 261"},"PeriodicalIF":0.0,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49270828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of Cytotoxic and Antitumor Potential of Passiflora quadrangularis 西番莲的细胞毒性和抗肿瘤潜力分析
Journal of Herbs, Spices and Medicinal Plants Pub Date : 2023-06-20 DOI: 10.1080/10496475.2023.2225147
Chittilappilly J Anjali, C. Pareeth, T. Babu
{"title":"Analysis of Cytotoxic and Antitumor Potential of Passiflora quadrangularis","authors":"Chittilappilly J Anjali, C. Pareeth, T. Babu","doi":"10.1080/10496475.2023.2225147","DOIUrl":"https://doi.org/10.1080/10496475.2023.2225147","url":null,"abstract":"ABSTRACT The cytotoxicity of ethanolic extract of Passiflora quadrangularis (PQ) leaves was analyzed on cancer cell lines by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Antitumor effect was analyzed on mouse solid and ascites tumor models. The phytochemical profile of the extract was analyzed by liquid chromatography-mass spectrometry (LC-MS). Apoptosis and cell cycle were analyzed by fluorescence resonance energy transfer (FRET) and flow cytometry. PQ exhibited cytotoxicity on Dalton’s lymphoma ascites (DLA) and Ehrlich’s ascites carcinoma cells with IC50 of 9.4 and 9.2 μg mL−1 and anti-proliferative effect on breast (MCF7) and colorectal (HCT116) cancer cell lines with IC50 of 166.5 and 107.09 μg mL−1, respectively. The extract did not show toxicity in normal rat intestinal cells IEC6 and murine macrophage cells RAW264.7. In ascites tumor model, the mean survival days of the animals increased to 25 ± 4.30 d in the treated group compared to untreated (21.2 ± 2.68 d). In DLA-induced solid model, the tumor weight decreased to 1.6 ± 0.9 g from 4.5 ± 0.58 g by treatment with 400 mg kg−1 b.w. extract. LC-MS analysis revealed the presence of genistein, kaempferol, isovitexin, and quercetin that are known for anticancer potential. The acute toxicity in mice revealed that PQ is nontoxic. FRET and flow cytometry analysis indicated an induction of apoptosis in PQ-treated cells","PeriodicalId":35803,"journal":{"name":"Journal of Herbs, Spices and Medicinal Plants","volume":"29 1","pages":"452 - 469"},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46347195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumor Reduction Potentials of Vernonia Cinerea Sesquiterpenes by Induction of Ferroptosis 斑蝥二萜类化合物诱导脱铁减瘤作用的研究
Journal of Herbs, Spices and Medicinal Plants Pub Date : 2023-05-25 DOI: 10.1080/10496475.2023.2217491
Jimsy Johnson, L. Varghese
{"title":"Tumor Reduction Potentials of Vernonia Cinerea Sesquiterpenes by Induction of Ferroptosis","authors":"Jimsy Johnson, L. Varghese","doi":"10.1080/10496475.2023.2217491","DOIUrl":"https://doi.org/10.1080/10496475.2023.2217491","url":null,"abstract":"ABSTRACT The anti lymphoma potentials of Vernonia cinerea were evaluated. In a short-term in vitro study, ethyl acetate extract (VCEA) was found to be cytotoxic to DLA cells with an LC50 of 61.24 μg mL−1. GC-MS analysis of VCEA revealed presence of several volatile molecules including nerolidol. Molecular docking study using nerolidol with Ferroportin-1 predicted strong binding affinity, indicating ferroptosis induction which was later confirmed by in vitro assays. VCEA also demonstrated strong reduction in the proliferation of YAC-1, another lymphoma cell line with G2/M arrest leading to apoptosis. The tumor reduction potentials of VCEA was further confirmed using the DLA-induced solid tumor model in mice.","PeriodicalId":35803,"journal":{"name":"Journal of Herbs, Spices and Medicinal Plants","volume":"29 1","pages":"438 - 451"},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43478744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Phytochemical Analysis and In Vitro Assessment of Extracts of Rhodobryum roseum for Antioxidant, Antibacterial and Anti-Inflammatory Activities 玫瑰杜鹃提取物抗氧化、抗菌和抗炎活性的植物化学分析及体外评价
Journal of Herbs, Spices and Medicinal Plants Pub Date : 2023-05-12 DOI: 10.1080/10496475.2023.2211288
Hiteshi Sabharwal, G. Shukla, K. Kondepudi, Ruchika Maurya, S. Kapila, Neha Dogra
{"title":"Phytochemical Analysis and In Vitro Assessment of Extracts of Rhodobryum roseum for Antioxidant, Antibacterial and Anti-Inflammatory Activities","authors":"Hiteshi Sabharwal, G. Shukla, K. Kondepudi, Ruchika Maurya, S. Kapila, Neha Dogra","doi":"10.1080/10496475.2023.2211288","DOIUrl":"https://doi.org/10.1080/10496475.2023.2211288","url":null,"abstract":"ABSTRACT The antibacterial, antioxidant and anti-inflammatory potential of Rhodobryum roseum extracts in organic solvents was investigated. The highest contents of total phenols, flavonoids, and antioxidants have been found in methanolic extract. Escherichia coli and Listeria monocytogenes were sensitive to the extracts, while Bacillus subtilis and Klebsiella pneumoniae were resistant. Anti-inflammatory potential of methanolic extract was assessed in the LPS-induced RAW 264.7 macrophage cell lines. The GC-MS of methanolic extract showed the predominance of phenolic acids, fatty acids and phytosterols, while terpenoids and flavonoids were identified by LC-MS analysis. FTIR confirmed the presence of O-H, C-H, C-N, C-F and SCN functional groups.","PeriodicalId":35803,"journal":{"name":"Journal of Herbs, Spices and Medicinal Plants","volume":"29 1","pages":"419 - 437"},"PeriodicalIF":0.0,"publicationDate":"2023-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43112331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethnobotanical Survey and Phytochemical Screening of Medicinal Plants Used in the Management of Asthma in Lagos Metropolis 拉各斯市哮喘防治药用植物的民族植物学调查和植物化学筛选
Journal of Herbs, Spices and Medicinal Plants Pub Date : 2023-04-28 DOI: 10.1080/10496475.2023.2207075
A. Igbari, Victoria Joan Ejugwu, G. Nodza, O. Ogundipe
{"title":"Ethnobotanical Survey and Phytochemical Screening of Medicinal Plants Used in the Management of Asthma in Lagos Metropolis","authors":"A. Igbari, Victoria Joan Ejugwu, G. Nodza, O. Ogundipe","doi":"10.1080/10496475.2023.2207075","DOIUrl":"https://doi.org/10.1080/10496475.2023.2207075","url":null,"abstract":"ABSTRACT A survey was carried out using a structured questionnaire to obtain information about medicinal plants used for the management of asthma in Lagos metropolis. Species with the highest use values (UV) were selected for phytochemical screening. In total, 79 respondents were interviewed and 36 species distributed in 23 plant families were identified. Based on the UV, the most important species were Olax subscorpiodea (UV=0.13), Crinum glaucum (UV=0.12), Allium ascalonicum (UV=0.09), Allium sativum (UV=0.06), Zingiber officinale (UV=0.05), and Securidaca longipendiculata (UV=0.05). Phytochemical screening revealed the presence of flavonoids, alkaloids, terpenes glycosides, phlobatannins, tannins, phenols, and saponins.","PeriodicalId":35803,"journal":{"name":"Journal of Herbs, Spices and Medicinal Plants","volume":"29 1","pages":"405 - 418"},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45290705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Syzygium aromaticum extracts debilitate Candida albicans by radically inhibiting its morphological plasticity and biofilm formation 丁香提取物通过从根本上抑制白色念珠菌的形态可塑性和生物膜的形成而使其衰弱
Journal of Herbs, Spices and Medicinal Plants Pub Date : 2023-04-02 DOI: 10.1080/10496475.2023.2196463
Omar K.H. Bani Domi, H. Darmani
{"title":"Syzygium aromaticum extracts debilitate Candida albicans by radically inhibiting its morphological plasticity and biofilm formation","authors":"Omar K.H. Bani Domi, H. Darmani","doi":"10.1080/10496475.2023.2196463","DOIUrl":"https://doi.org/10.1080/10496475.2023.2196463","url":null,"abstract":"ABSTRACT The effects of Syzygium aromaticum extracts on the growth, germ tube production, biofilm formation and adhesion of Candida albicans to human buccal epithelial cells (BEC) were investigated. We found larger zones of inhibition of growth of C. albicans with the essential oil (EO) and methanolic extract (ME) than amphotericin B. Similarly, the MIC values for the EO and ME were lower than that of amphotericin B. The EO and ME caused greater reductions in biofilm formation than amphotericin-B. Pre-treatment of C. albicans and BEC with the EO caused greater reductions in adhesion to BEC than amphotericin B.","PeriodicalId":35803,"journal":{"name":"Journal of Herbs, Spices and Medicinal Plants","volume":"29 1","pages":"392 - 404"},"PeriodicalIF":0.0,"publicationDate":"2023-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47056593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Viscum monoicum: A New Source of Polyphenolic Compounds Responsible for Antioxidant and Anti-Inflammatory Activities 一种具有抗氧化和抗炎活性的多酚类化合物的新来源
Journal of Herbs, Spices and Medicinal Plants Pub Date : 2023-03-15 DOI: 10.1080/10496475.2023.2182394
K. S. Ahmed, M. Farzana, S. E. Rahman, I. Jahan, T. Khan, M. A. Al-Mansur, Nadia Sultana, Hemayet Hossain
{"title":"Viscum monoicum: A New Source of Polyphenolic Compounds Responsible for Antioxidant and Anti-Inflammatory Activities","authors":"K. S. Ahmed, M. Farzana, S. E. Rahman, I. Jahan, T. Khan, M. A. Al-Mansur, Nadia Sultana, Hemayet Hossain","doi":"10.1080/10496475.2023.2182394","DOIUrl":"https://doi.org/10.1080/10496475.2023.2182394","url":null,"abstract":"ABSTRACT Viscum monoicum has been used as a traditional medicinal plant for the treatment of many ailments that include pain, neuropharmacological disorders as well as various types of tumors. This study was designed to investigate the polyphenolic compound, antioxidant, and anti-inflammatory activities of the ethanolic extract of Viscum monoicum (EVM). The extract was subjected to HPLC-DAD analysis for the quantification of polyphenols. In addition, DPPH, ABTS free radical scavenging, reducing power, total antioxidant capacity, phenolic, and flavonoid content was measured for antioxidant activities of EVM. Besides, the anti-inflammatory activity of EVM was studied using carrageenan and histamine-induced rat paw edema at different doses. High levels of ellagic acid and (+)-catechin hydrate (410.15 and 340.88 mg/100 g extract, respectively) were determined for the first time through HPLC in EVM. IC50 of EVM was significant in DPPH and ABTS scavenging assay compared to that of ascorbic acid. The total antioxidant capacity, total phenolic, and total flavonoid contents were estimated and found significant amount equivalent to standard. At a dose of 400 mg kg−1, a significant anti-inflammatory activity (P<0.01) was observed in rats at both carrageenan and histamine-induced edema test models with a reduction in the paw volume; in comparison to indomethacin. Therefore, the results suggest that polyphenolic compounds might be responsible for the antioxidant and anti-inflammatory activities of EVM.","PeriodicalId":35803,"journal":{"name":"Journal of Herbs, Spices and Medicinal Plants","volume":"29 1","pages":"336 - 355"},"PeriodicalIF":0.0,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47600178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Phenolic Components and Antioxidant Capacity of Six Wild Passiflora Species from the Andean Region of Colombia 哥伦比亚安第斯地区6种野生西番莲的酚类成分及其抗氧化能力
Journal of Herbs, Spices and Medicinal Plants Pub Date : 2023-02-27 DOI: 10.1080/10496475.2023.2181260
Elizabeth Murillo, Á. Jiménez, A. Velásquez, Hernán Clavijo, Carmen Elisa Velásquez
{"title":"Phenolic Components and Antioxidant Capacity of Six Wild Passiflora Species from the Andean Region of Colombia","authors":"Elizabeth Murillo, Á. Jiménez, A. Velásquez, Hernán Clavijo, Carmen Elisa Velásquez","doi":"10.1080/10496475.2023.2181260","DOIUrl":"https://doi.org/10.1080/10496475.2023.2181260","url":null,"abstract":"ABSTRACT Methanolic extracts were prepared from aerial biomass of wild populations of Passiflora coriacea, P. capsularis, P. magdalenae, P. smithii, P. vitifolia, and P. pittieri and evaluated for total phenols, tannins, and flavonoids. The qualitative and quantitative profiles of the extracts were established by UHPLC-ESI/MSMS, and their capacity to quench DPPH∙ and ABTS∙+ radicals was determined. There were positive correlations between the phenolic content and antioxidant capacity for all species analyzed, highlighting to P. vitifolia and P. pittieri which exhibited the highest values for all the determined parameters. Passiflora species from the Colombian Andean, may be a potential source of bioactive metabolites.","PeriodicalId":35803,"journal":{"name":"Journal of Herbs, Spices and Medicinal Plants","volume":"29 1","pages":"319 - 335"},"PeriodicalIF":0.0,"publicationDate":"2023-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43223723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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