Prague medical report最新文献_第5页

A Rare Case of Neuromyelitis Optica Spectrum Disorder Secondary to Primary Sjögren's Syndrome in an Older Woman. 一名老年妇女继发于原发性斯约格伦综合征的神经脊髓炎谱系障碍罕见病例。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.21

Hasan Huseyin Zorlu, Suleyman Emre Kocyigit

引用次数: 0

Janus Kinase Inhibitors in the Treatment of Alopecia Areata. Janus激酶抑制剂治疗斑秃。

Prague medical report Pub Date : 2023-01-01 DOI: 10.14712/23362936.2023.1

Athanasios J Stefanis

引用次数: 2

The Neuropsychiatric Aspect of the Chronic Viral Hepatitis. 慢性病毒性肝炎的神经精神病学方面。

Prague medical report Pub Date : 2023-01-01 DOI: 10.14712/23362936.2023.8

Tatyana Vasiliyevna Polukchi, Gulzhan Narkenovna Abuova, Yelena Alekseevna Slavko

{"title":"The Neuropsychiatric Aspect of the Chronic Viral Hepatitis.","authors":"Tatyana Vasiliyevna Polukchi, Gulzhan Narkenovna Abuova, Yelena Alekseevna Slavko","doi":"10.14712/23362936.2023.8","DOIUrl":"https://doi.org/10.14712/23362936.2023.8","url":null,"abstract":"Chronic viral hepatitis is a systemic disease characterized by a wide range of extrahepatic manifestations, such as cognitive impairment, chronic fatigue, sleep disorders, depression, anxiety and a decrease in quality of life. This article presents a summary of the main theories and hypotheses about the occurrence of cognitive impairment, features of treatment of patients with chronic viral hepatitis. Often, extrahepatic manifestations can outstrip the clinical manifestations of liver damage itself, which requires the use of additional diagnostic and treatment methods, and they can also significantly change the treatment tactics and prognosis of the disease. Changes in neuropsychological parameters and cognitive impairments are often recorded in patients with chronic viral hepatitis at stages characterized by the absence of significant liver fibrosis and liver cirrhosis. These changes usually occur regardless of the genotype of the infection and in the absence of structural damage to the brain. The purpose of this review is to study the main aspects of the formation of cognitive impairment in patients with chronic hepatitis, cirrhosis of viral etiology.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"124 2","pages":"94-107"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9857351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vaping Associated Acute Eosinophilic Pneumonia: A Clinical and Radiologic Mimicker of COVID-19. Vaping相关急性嗜酸性肺炎：新冠肺炎的临床和放射学模拟。

Prague medical report Pub Date : 2023-01-01 DOI: 10.14712/23362936.2023.22

Alyssa Bonnier, Anum Nida, Woon Hean Chong, Santu Saha, Biplab K Saha

{"title":"Vaping Associated Acute Eosinophilic Pneumonia: A Clinical and Radiologic Mimicker of COVID-19.","authors":"Alyssa Bonnier, Anum Nida, Woon Hean Chong, Santu Saha, Biplab K Saha","doi":"10.14712/23362936.2023.22","DOIUrl":"https://doi.org/10.14712/23362936.2023.22","url":null,"abstract":"Acute eosinophilic pneumonia (AEP) is a rare cause of respiratory failure. It is primarily a disease of smokers, either a new smoker or an existing one with a recent increase in cigarette consumption. Other risk factors include toxic gas exposure, inhalational illicit drugs, and smoking marijuana. AEP has also been reported in patients with e-cigarette or vaping associated lung injury (EVALI). We present the case of a 20-year-old male who presented to the hospital with acute respiratory failure. The patient has been vaping heavily for the past three months and started smoking three days before presenting to the emergency department. He was hypertensive, tachycardic, tachypneic, and required high-flow nasal cannula to maintain SpO2 > 92%. His condition deteriorated in the first 24 hours following hospitalization requiring noninvasive positive pressure ventilation. Bronchoalveolar lavage revealed an eosinophil count of 36%. Bronchoalveolar lavage (BAL) cytology revealed lipid-laden macrophages. He was diagnosed with AEP due to EVALI, and the patient was treated with high dose corticosteroid with subsequent improvement. Before the bronchoscopic evaluation, the clinical and radiologic findings were consistent with COVID-19, and the patient was tested twice for SARS-CoV-2 PCR. In the appropriate clinical setting, AEP should be considered in the differential diagnoses of community-acquired pneumonia, acute respiratory distress syndrome (ARDS), and COVID-19, especially in this pandemic era.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"124 3","pages":"283-292"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41150628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Demographic and Clinical Characteristics in Distinguishing Testicular Torsion from Torsion of the Appendix Testis: A Single-center Retrospective Study. 人口统计学和临床特征在区分睾丸扭转和附件睾丸扭转中的作用：一项单中心回顾性研究。

Prague medical report Pub Date : 2023-01-01 DOI: 10.14712/23362936.2023.20

Zlatan Zvizdic, Amila Aganovic, Emir Milisic, Asmir Jonuzi, Denisa Zvizdic, Semir Vranic

{"title":"The Role of Demographic and Clinical Characteristics in Distinguishing Testicular Torsion from Torsion of the Appendix Testis: A Single-center Retrospective Study.","authors":"Zlatan Zvizdic, Amila Aganovic, Emir Milisic, Asmir Jonuzi, Denisa Zvizdic, Semir Vranic","doi":"10.14712/23362936.2023.20","DOIUrl":"https://doi.org/10.14712/23362936.2023.20","url":null,"abstract":"The acute scrotum (AS) in the pediatric population is a medical emergency. AS is usually caused by testicular torsion (TT) and torsion of the appendix testis (TAT). The current study explored which demographic and clinical characteristics can help distinguish between TT and TAT. We analyzed all children ≤16 years who underwent surgical exploration for AS. The patients were divided into Group 1/TT and Group 2/TAT. Ninety patients were included in the study (24 with TT and 66 with TAT). The peak incidence of TT was significantly higher than in the TAT group (p<0.001). Scrotal pain was more prevalent in the TAT group (p=0.02), whereas systemic signs (nausea/vomiting and abdominal pain) affected more frequently the TT patients (p=0.003 and p<0.001, respectively). The duration of symptoms was significantly longer in the TAT group (p<0.001). The duration of symptoms in the TT cohort significantly impacted the testicular salvage (p=0.008). Color Doppler ultrasound (CDUS) findings of absent/decreased testicular blood flow in the affected testis strongly favored the diagnosis of TT (p<0.001). The older age, shorter duration of symptoms, systemic signs, and CDUS findings can help distinguish between the two most common acute scrotum causes.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"124 3","pages":"255-264"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41111345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Screening for SARS-COV-2 Using RT-qPCR in Patients with Hematologic Neoplasms Receiving Chemotherapy. 利用RT-qPCR技术筛查血液肿瘤化疗患者的SARS-COV-2

Prague medical report Pub Date : 2023-01-01 DOI: 10.14712/23362936.2023.3

Ignacio Martín Santarelli, Mariela Sierra, Sofía Isabel Fernández

引用次数: 0

Cord Herniation through the Site of Undiagnosed Thoracic Dermoid Tumour during Spinal Anaesthesia; Report of a Case and Describing Ways to Avoid. 脊髓麻醉过程中经未确诊胸皮样肿瘤部位的脊髓疝案例报告及避免方法描述。

Prague medical report Pub Date : 2023-01-01 DOI: 10.14712/23362936.2023.15

Mansour Parvaresh, Eshagh Bahrami, Sayedali Ahmadi, Arash Fattahi, Ali Farid

引用次数: 0

Osteomyelitis and Thrombosis in a Newborn with Group A Streptococcus Infection. a组链球菌感染新生儿的骨髓炎和血栓形成。

Prague medical report Pub Date : 2023-01-01 DOI: 10.14712/23362936.2023.23

Georgios Mitsiakos, Dimitra Gialamprinou, Christos Tsakalidis, Evgenia Babatseva, Maria Lithoxopoulou, Elisavet Diamanti

{"title":"Osteomyelitis and Thrombosis in a Newborn with Group A Streptococcus Infection.","authors":"Georgios Mitsiakos, Dimitra Gialamprinou, Christos Tsakalidis, Evgenia Babatseva, Maria Lithoxopoulou, Elisavet Diamanti","doi":"10.14712/23362936.2023.23","DOIUrl":"https://doi.org/10.14712/23362936.2023.23","url":null,"abstract":"Neonatal osteomyelitis (OM), although exceptionally rare, has been linked to detrimental sequel, as diagnosis in the early stages is challenging and any delay in treatment can lead to disturbance in skeletal growth. In pediatric OM the most commonly grown bacteria is Staphylococcus aureus followed by group A Streptococcus (GAS). Notwithstanding, sepsis-induced coagulopathy is a well-known entity in children and adults, still sepsis-associated thrombosis is sparsely observed. we present a case of a newborn with GAS associated OM and thrombosis. A term neonate on the 11th day of life was referred to our NICU due to right (R) lower limb edema, cyanosis and core temperature up to 39 °C. Late onset sepsis was suspected and started on vancomycin and amikacin. A colour Doppler scan showed thrombosis of the R common femoral vein. The neonate started on iv unfractionated heparin. Ampicillin was added given positive for GAS blood culture. An MRI on the 5th day of admission, showed evidence of thrombosis resolution. On the 14th day of admission, a bone Tc99 scan showed evidence of OM of R femur. Antibiotic treatment switched to amoxicillin per os. The management was restricted to anticoagulant therapy with low molecular weight heparin for 3 months and antibiotic therapy for 6 months without surgery intervention and the patient recovered and discharged at 42 days of age. Early diagnosis and treatment of neonatal osteomyelitis can prevent bone destruction. Sepsis-associated thrombosis is barely observed during osteomyelitis, yet it should be considered as an emerged case requiring prompt treatment.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"124 3","pages":"293-300"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41152563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Critical Analysis of the Magnetic Resonance Imaging Lesion Diameter Threshold for Adverse Pathology Features. 磁共振成像病变直径阈值对不良病理特征的关键分析。

Prague medical report Pub Date : 2023-01-01 DOI: 10.14712/23362936.2023.4

Yavuz Onur Danacioglu, Rustu Turkay, Omer Yildiz, Salih Polat, Yusuf Arikan, Hakan Polat, Mustafa Gurkan Yenice, Halil Firat Baytekin, Ercan Inci, Ali İhsan Tasci

{"title":"A Critical Analysis of the Magnetic Resonance Imaging Lesion Diameter Threshold for Adverse Pathology Features.","authors":"Yavuz Onur Danacioglu, Rustu Turkay, Omer Yildiz, Salih Polat, Yusuf Arikan, Hakan Polat, Mustafa Gurkan Yenice, Halil Firat Baytekin, Ercan Inci, Ali İhsan Tasci","doi":"10.14712/23362936.2023.4","DOIUrl":"https://doi.org/10.14712/23362936.2023.4","url":null,"abstract":"To investigate the relationship between lesion size determined using multiparametric magnetic resonance imaging (mpMRI) and histopathological findings of specimens obtained after mpMRI fusion biopsy and radical prostatectomy (RP). We retrospectively analysed 290 patients with PCa who underwent an MRI fusion biopsy. We measured the diameter of suspicious tumour lesions on diffusion-weighted mpMRI and stratified the cohort into two groups. Group A included patients with a suspicious tumour lesion 10 mm and Group B included those with a suspicious tumour lesion > 10 mm. In Group B, the PI-RADS score determined in mpMRI was higher than Group A, and there was a statistically significant difference between the two groups in terms of clinical T-stage. The PCa detection rate and the number of positive cores were statistically significantly higher in Group B than in Group A. In addition, there was a statistically significant difference between the two groups in relation to the biopsy, the International Society of Urological Pathology (ISUP) grade values, and the presence of clinically significant PCa. In Group B, pathological T-stage and extraprostatic extension (EPE) and surgical margin (SM) positivity were found to be higher among the patients who underwent RP. In the multivariate analysis, the mpMRI lesion size being > 10 mm was found to be an independent predictive factor for SM and EPE positivity. The clinical results of this study support the modification of the lesion size threshold as 10 mm for use in the differentiation of PI-RADS scores 4 and 5.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"124 1","pages":"40-51"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10699383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of the Causes of Newborn Priapism: A Retrospective Clinical Study. 新生儿阴茎勃起障碍原因分析:回顾性临床研究。

Prague medical report Pub Date : 2023-01-01 DOI: 10.14712/23362936.2023.6

Ekrem Guner, Fatih Akkas, Osman Ozdemir, Yusuf Arikan, Kamil Gokhan Seker, Emre Sam

{"title":"Analysis of the Causes of Newborn Priapism: A Retrospective Clinical Study.","authors":"Ekrem Guner, Fatih Akkas, Osman Ozdemir, Yusuf Arikan, Kamil Gokhan Seker, Emre Sam","doi":"10.14712/23362936.2023.6","DOIUrl":"https://doi.org/10.14712/23362936.2023.6","url":null,"abstract":"Priapism is a rare condition in the newborn. The aim of this study was to investigate the demographic, etiologic and clinical features of neonatal priapism. We retrospectively analysed the data of 11 patients diagnosed with neonatal priapism in the neonatal intensive care unit between 2000 and 2019. Priapism was defined as an erection in the neonatal period, lasting more than 4 hours. Etiological examinations revealed polycythemia in one (9.09%) patient, D-dimer elevation in three patients, and heterozygous methyltetrahydrofolate 667 gene mutations in one patient. Other patients were considered idiopathic. Detumescence was achieved in all 11 (100%) patients during the follow-up period. The median hospitalization duration was 6 (IQR [4, 8]; range, 2-9) days. The median follow-up duration was 38 (IQR [30, 42]; range, 13-94) months for patients followed-up in our hospital after discharge. Neonatal priapism is a rare condition. Successful treatment results can be achieved with conservative methods. Data acquired from our study showed that diseases with a tendency to hypercoagulation belong to the etiology by damaging penile microcirculation and make the response to conservative treatment more challenging.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"124 1","pages":"58-66"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10699385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0