Prague medical report最新文献_第6页

Morphometry of Iliac Bones - A Useful Guide for Harvesting Bone Grafts. 髂骨形态计量学-骨移植收获的有用指南。

Prague medical report Pub Date : 2025-01-01 DOI: 10.14712/23362936.2025.2

Nidhi Mangla, Surbhi Wadhwa, Sumit Sural, Sabita Mishra, Neelam Vasudeva

{"title":"Morphometry of Iliac Bones - A Useful Guide for Harvesting Bone Grafts.","authors":"Nidhi Mangla, Surbhi Wadhwa, Sumit Sural, Sabita Mishra, Neelam Vasudeva","doi":"10.14712/23362936.2025.2","DOIUrl":"10.14712/23362936.2025.2","url":null,"abstract":"Iliac crest is common site for harvesting bone grafts. Morphometry of iliac crest is of vital importance in orthopedic surgery. Measurements were done on male (n=85) and female (n=85) hip bones. Length of iliac crest, thickness of iliac crest and ilium were measured. Thickness was measured at pre-defined points on crest and ilium 2 cm apart starting from anterior superior iliac spine (ASIS). Ilium was measured at a depth of 2.5 cm from crest. Statistical analysis was done. Iliac crests were longer in male bones. Ventral iliac crest was thickest at 6 cm from ASIS in both sexes. While iliac crest bore minimum thickness at 12 cm and 10 cm from ASIS in male and female bones respectively, however at 2.5 cm below iliac crest surface ilium was thickest at 4 cm from ASIS and at ASIS in male and female bones respectively. In case of male bones, dorsal part of iliac crest was thickest at 2.15 ± 1.29 cm from posterior superior iliac spine (PSIS) while in females it was at 1.78 ± 1.31 cm from PSIS. In dorsal part of ilium, it was observed at 2.31 ± 1.47 cm and 1.9 ± 1.79 cm from PSIS for male and female bones respectively. This study provided detailed variable morphometry and significant sexual dimorphism observed in iliac crest and ilium. Thickest safe zones in both sexes are a useful guide for harvesting appropriate bone grafts.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"126 1","pages":"9-16"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eccrine Hidrocystoma of Eyelid Masquerading as Epidermal Inclusion Cyst: A Rare Case Report with Review of Literature. 眼睑汗液囊肿伪装表皮包涵性囊肿1例并文献复习。

Prague medical report Pub Date : 2025-01-01 DOI: 10.14712/23362936.2025.7

Gyanendra Singh, Mamta Singh, Palak Thakkar, Parth Goswami

引用次数: 0

A Comprehensive Guide to Typhoidal Anemia. 伤寒性贫血综合指南。

Prague medical report Pub Date : 2025-01-01 DOI: 10.14712/23362936.2025.10

Jayanta Deb, Suddha Sattwa Bandyopadhyay, Sanjit Debnath, Saurabh Gupta

{"title":"A Comprehensive Guide to Typhoidal Anemia.","authors":"Jayanta Deb, Suddha Sattwa Bandyopadhyay, Sanjit Debnath, Saurabh Gupta","doi":"10.14712/23362936.2025.10","DOIUrl":"https://doi.org/10.14712/23362936.2025.10","url":null,"abstract":"Typhoid fever, caused primarily by Salmonella Typhi and Paratyphi, stands as a significant global health concern, with complications extending beyond the typical gastrointestinal manifestations. This review systematically examines the intricate relationship between typhoid fever and hematologic complications, collectively referred to as typhoidal anemia. Hematological abnormalities, including changes in blood profiles and bone marrow responses, are scrutinized, providing a comprehensive understanding of the disease's impact on physiological systems. Specific populations, such as immunocompromised individuals, sickle cell anemia patients, and children in resource-limited settings, reveal varied susceptibilities and outcomes. Complications, such as psoas abscess and secondary hemophagocytic lymphohistiocytosis, are explored, highlighting the multifaceted nature of the disease. The distinct contributions of Salmonella Typhi and Paratyphi to anemia are elucidated, shedding light on the pathophysiological mechanisms involved. Global prevalence and epidemiological variations offer valuable perspectives, underscoring the importance of regional nuances in disease manifestation. Challenges in accurate diagnosis and treatment limitations are acknowledged, emphasizing the need for continued research to enhance diagnostic precision and therapeutic strategies. Insights into long-term effects, prognosis, and the influence of host factors contribute to a holistic understanding of typhoidal anemia. The review concludes by identifying critical gaps in knowledge, advocating for ongoing research initiatives and heightened awareness campaigns. The synthesis of diverse findings provides a comprehensive overview of typhoidal anemia, underscoring the imperative of continued research and awareness for improved patient care and global public health.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"126 2","pages":"55-62"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation of Ki-67 Expression with the Stage of Disease in Patients of Colorectal Carcinoma. 结直肠癌患者Ki-67表达与疾病分期的关系

Prague medical report Pub Date : 2025-01-01 DOI: 10.14712/23362936.2025.12

Ashutosh Nagpal, Poras Chaudhary

{"title":"Correlation of Ki-67 Expression with the Stage of Disease in Patients of Colorectal Carcinoma.","authors":"Ashutosh Nagpal, Poras Chaudhary","doi":"10.14712/23362936.2025.12","DOIUrl":"https://doi.org/10.14712/23362936.2025.12","url":null,"abstract":"Colorectal carcinoma (CRC) is a multifactorial disease process with several factors influencing prognosis. CRC is associated with the expression of multiple cell proliferating markers such as Ki-67/MIB-1. This study was aimed to examine possible correlations between Ki-67 expression and the stage of colorectal carcinoma. This was a single centre prospective study including 93 patients who underwent surgery for colorectal carcinoma. Expression of Ki-67 was assessed by immunohistochemistry on formalin-fixed paraffin-embedded tumour tissue blocks. Categorical variables data were presented as number with corresponding percentage. Continuous data were analysed using parametric tests as applicable and categorical data using nonparametric tests. The level of significance α = 0.05 and P-value < 0.05 was considered statistically significant. The average Ki-67 expression was 77.66% (SD [standard deviation] = 9.68%) with a range of 60 to 90%. Patients with nodal involvement and larger size had a higher Ki-67 expression. To assess statistical significance, the cut-off for Ki-67 expression was set at 70%. Of 66, 48 (72.7%) adenocarcinomas and 12/18 (66.66%) mucinous adenocarcinomas had Ki-67 expression above cut-off as compared to signet ring cell variety. Ki-67 expression in colorectal carcinoma signifies mitotic activity of the tumour. Thus, it could be used as an adjunct to the existing diagnostic arsenal to help overcome its limitation in gauging the functional status of tissues.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"126 2","pages":"75-81"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ormond's Disease - 26 Years of Experience at One Centre. 奥蒙德病-在一个中心26年的经验。

Prague medical report Pub Date : 2025-01-01 DOI: 10.14712/23362936.2025.1

Miroslav Průcha, Pavel Zdráhal, Radek Kříž, Alena Šnajdrová, Luděk Voska

{"title":"Ormond's Disease - 26 Years of Experience at One Centre.","authors":"Miroslav Průcha, Pavel Zdráhal, Radek Kříž, Alena Šnajdrová, Luděk Voska","doi":"10.14712/23362936.2025.1","DOIUrl":"10.14712/23362936.2025.1","url":null,"abstract":"Ormond's disease is a systemic autoimmune disease with serious complications. We present our retrospective analysis of 83 patients diagnosed with and treated for idiopathic retroperitoneal fibrosis (Ormond's disease) in our department from 1997 to 2023. In this retrospective study, we analysed the diagnostic approaches, the clinical history and surgical and immunosuppressive therapies, and their subsequent effects on our patients. Patients with established disease activity were given immunosuppressive treatment, using corticosteroids alone or in combination with azathioprine, in patients with exacerbation of the disease mycophenolate mofetil. Three patients with Ormond's disease and systemic complications (IgG4-related disease) were treated with rituximab. In the entire cohort, 83 patients received immunosuppressive therapy; the next 5 patients did not receive this treatment because they did not present inflammatory activity from the disease. In these 83 patients, computed tomography showed that immunosuppressive treatment resulted in partial or complete regression of the inflammatory infiltrate. Out of the 83 patients, 10 patients experienced disease exacerbation 7 and 24 months after the immunosuppressive treatment was discontinued. The follow-up ranged from 24 months to 26 years.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"126 1","pages":"3-8"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Freeman-Sheldon Syndrome: A Rare Case Report with Dental Perspective. 弗里曼-谢尔登综合征：一个罕见的病例报告与牙科的角度。

Prague medical report Pub Date : 2025-01-01 DOI: 10.14712/23362936.2025.37

Sahil Mustafa Kidwai, Suman Sen, Nikil Kumar Jain, Sudhir Ramesh Maheshkar

引用次数: 0

Navigating the Risks of Dental Aspiration in Older Adults: A Case Study of Prompt Diagnosis and Intervention. 引导老年人误吸牙的风险：及时诊断和干预的案例研究。

Prague medical report Pub Date : 2025-01-01 DOI: 10.14712/23362936.2025.13

Louise Cardoso Fava Ferreira Dos Santos, Marcelo de Queiroz Pereira da Silva, Márcio Luís Duarte

{"title":"Navigating the Risks of Dental Aspiration in Older Adults: A Case Study of Prompt Diagnosis and Intervention.","authors":"Louise Cardoso Fava Ferreira Dos Santos, Marcelo de Queiroz Pereira da Silva, Márcio Luís Duarte","doi":"10.14712/23362936.2025.13","DOIUrl":"https://doi.org/10.14712/23362936.2025.13","url":null,"abstract":"Foreign body aspiration is a significant cause of respiratory distress in geriatric patients, often leading to severe complications if not promptly identified and treated. Dental materials account for approximately 15-20% of foreign body aspirations in adults, with symptoms that can include dyspnea, localized wheezing, and, in some cases, cyanosis and pneumonia. We report the case of a 60-year-old man who aspirated a dental crown, resulting in shortness of breath. A computed tomography scan revealed the crown lodged in the left main bronchus. The patient underwent successful bronchoscopy for foreign body removal and experienced a full recovery without complications. Neurological conditions, such as epilepsy or Parkinson's disease, increase the risk of aspiration, particularly in elderly patients, in which symptoms may be misdiagnosed due to their nonspecific presentation. While the right bronchus is more commonly affected due to anatomical structure, foreign body aspiration in the left bronchus also warrants attention. This case underscores the importance of rapid imaging and bronchoscopy to reduce the risk of morbidity and mortality from aspiration events. Increased awareness and timely intervention are essential for improving patient outcomes in cases of dental and other foreign body aspirations in older populations.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"126 2","pages":"82-85"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Stroke on Electromyographic Activity, Respiratory Muscle Strength, and Pulmonary Function. 中风对肌电活动、呼吸肌力量和肺功能的影响。

Prague medical report Pub Date : 2025-01-01 DOI: 10.14712/23362936.2025.31

Camila Roza Gonçalves, Marcelo Palinkas, Gabriel Pádua da Silva, Robson Felipe Tosta Lopes, Edson Donizetti Verri, Isabella Cícero de Souza, Guilherme Gallo Costa Gomes, Evandro Marianetti Fioco, Selma Siéssere, Simone Cecilio Hallak Regalo

{"title":"Effects of Stroke on Electromyographic Activity, Respiratory Muscle Strength, and Pulmonary Function.","authors":"Camila Roza Gonçalves, Marcelo Palinkas, Gabriel Pádua da Silva, Robson Felipe Tosta Lopes, Edson Donizetti Verri, Isabella Cícero de Souza, Guilherme Gallo Costa Gomes, Evandro Marianetti Fioco, Selma Siéssere, Simone Cecilio Hallak Regalo","doi":"10.14712/23362936.2025.31","DOIUrl":"10.14712/23362936.2025.31","url":null,"abstract":"Stroke is a condition characterized by the sudden onset of clinical signs and symptoms, with persistent neurological deficits lasting more than twenty-four hours. This disease causes changes in cerebral blood circulation, impairing brain function either focally or globally. This observational study aimed to evaluate the respiratory function of subjects who suffered an ischemic or hemorrhagic stroke more than five years ago and compare them to a without neurological disorder group. Twenty-four subjects aged between 30 and 80 years participated, divided into two groups: stroke (n=12) and without neurological disorder (n=12). All analyses were conducted with a 5% significance level (Student's t-test). The results indicated that the stroke group showed significant changes compared to without neurological disorder group, including increased activity of respiratory and accessory muscles, as well as reduced respiratory muscle strength. However, spirometric evaluation did not reveal significant differences between the groups. The authors suggest that subjects with stroke exhibit neuromuscular deficits, with changes in the electromyographic activity of respiratory and accessory muscles, reduced respiratory muscle strength, and impaired lung volumes and capacities.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"126 4","pages":"193-200"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145890279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biofilm-forming Ability of Anaerobic Bacterial Strains Isolated from Patients Diagnosed with Periodontitis. 牙周炎患者厌氧菌的生物膜形成能力。

Prague medical report Pub Date : 2025-01-01 DOI: 10.14712/23362936.2025.22

Ivan Skliar, Maryna Kryvtsova, Yevhen Kostenko, Marianna Savenko

{"title":"Biofilm-forming Ability of Anaerobic Bacterial Strains Isolated from Patients Diagnosed with Periodontitis.","authors":"Ivan Skliar, Maryna Kryvtsova, Yevhen Kostenko, Marianna Savenko","doi":"10.14712/23362936.2025.22","DOIUrl":"https://doi.org/10.14712/23362936.2025.22","url":null,"abstract":"Bacterial biofilms represent the primary causative agents of pathogenic processes within the oral cavity. Biofilm microorganisms exhibit heightened resistance to adverse environmental factors. The objective of this study was to ascertain the biofilm-forming potential of clinical strains of anaerobic microorganisms isolated from the periodontal pocket of patients diagnosed with periodontitis. The study of biofilm formation was carried out by the method (Djordjevic et al., 2002) using flat-bottomed 96-well polystyrene microtitration plates. Biofilm formation was determined by staining with 0.1% crystal violet. The study utilised clinical strains isolated from the periodontal pocket of 61 patients diagnosed with grade III chronic periodontitis. Of these, 30 strains belonging to three bacterial species were selected for further analysis: Porphyromonas asaccharolytica, Slackia exigua, and Schaalia odontolytica. Among the Porphyromonas asaccharolytica strains, 80% formed biofilm; the figure for Slackia exigua was 90%, and for Schaalia odontolytica - 80%. In total, 25 strains were capable of biofilm formation. The results indicate that the isolated strains of Porphyromonas asaccharolytica, Slackia exigua, and Schaalia odontolytica exhibited a significant capacity for biofilm formation (83.3% of the strains formed biofilm), particularly Slackia exigua strains, which exhibited the highest number of strains with high biofilm formation ability - 5 (16.6%). It is also noteworthy that these microorganisms exhibited a moderate persistence frequency (16.4% each), of the total sample of microbial biocenoses from inflammatory periodontal soft tissue areas.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"126 3","pages":"144-150"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145087530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Isolated Trapezium Fracture: A Rare and Challenging Diagnosis. 孤立的梯形骨折：罕见且具有挑战性的诊断。

Prague medical report Pub Date : 2025-01-01 DOI: 10.14712/23362936.2025.38

Jheniffer Rodrigues Cação, Márcio Luís Duarte

{"title":"Isolated Trapezium Fracture: A Rare and Challenging Diagnosis.","authors":"Jheniffer Rodrigues Cação, Márcio Luís Duarte","doi":"10.14712/23362936.2025.38","DOIUrl":"https://doi.org/10.14712/23362936.2025.38","url":null,"abstract":"Isolated trapezium fractures are a rare type of injury, accounting for approximately 4% of all carpal fractures. Due to their nonspecific symptoms and difficulty in detection with conventional radiography, these fractures are often underdiagnosed. This case report details a 22-year-old male who sustained a trapezium fracture after a motorcycle accident. The patient presented with wrist pain and mild edema, but radiographs were normal. However, computed tomography (CT) revealed a small fracture in the dorsal portion of the trapezium. Conservative treatment with wrist immobilization was administered, resulting in full recovery. The article discusses the rarity of trapezium fractures, their mechanisms of injury, diagnostic challenges, and treatment options. The use of imaging techniques such as CT and magnetic resonance imaging plays a crucial role in diagnosis, as they can detect fractures that may not be visible on plain X-rays. Early detection and treatment are essential to prevent complications such as arthritis, nonunion, and loss of thumb function. While there is no consensus on the optimal treatment approach, conservative management with immobilization or surgical interventions such as open reduction and internal fixation or closed reduction with pin placement are commonly used.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"126 4","pages":"243-245"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145890311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0