{"title":"Serum and Urine Levels of Magnesium in Adult Males with Type 2 Diabetes Mellitus in Jeddah, Saudi Arabia","authors":"S. M. Farid","doi":"10.5505/IAS.2016.27147","DOIUrl":"https://doi.org/10.5505/IAS.2016.27147","url":null,"abstract":"","PeriodicalId":351803,"journal":{"name":"medical journal of islamic world academy of sciences","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131017036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A comparative study on C-reactive protein and gamma-glutamyl transferase as novel inflammatory markers of type 2 diabetes mellitus","authors":"T. K. Bandyopadhyay","doi":"10.5505/ias.2018.22309","DOIUrl":"https://doi.org/10.5505/ias.2018.22309","url":null,"abstract":"Tushar Kanti Bandyopadhyay purulia Govt. Medical College, purulia, West Bengal, India. e-mail: drtkban011@gmail.com IntroductIon research in the last few years has linked oxidative stress (oS) and inflammation to β-cell dysfunction resulting from chronic exposure to hyperglycemia (1, 2), free fatty acids, or a combination of the two. A growing body of data (3) reinforces the concept that inflammation also plays an important role in the pathogenesis of type 2 diabetes mellitu (dM) and links dM with concomitant conditions with inflammatory components. dM is a group of metabolic diseases characterized by hyperglycemia resulting from defects of insulin secretion, insulin action, or both. type 2 dM is caused by a combination of resistance of insulin action and an inadequate compensatory insulin secretory response. this form of dM accounts for approximately 90%–95% of those with dM and was previously referred to as noninsulin-dependent dM (nIddM) or adult-onset dM. Prospective studies have described that a high level of gamma-glutamyl transferase (GGt) is associated with the subsequent development of diabetes. recently, serum GGt has been recognized as a marker of oxidative stress. Indeed oxidative processes are key components of chronic inflammation acting on multiple pathways and amplifying inflammatory reactions. Further activation of inflammatory processes may contribute to the development of type 2 dM (5-7). c-reactive protein (crP) is considered to be a major inflammatory cytokine that functions as a nonspecific defense mechanism in response to tissue injury or infection. recent prospective studies have suggested a relationship between an elevated level of crP an increasing risk of developing type 2 dM (8-10). ABSTRACT Studies in the last few years have linked oxidative stress and inflammation to beta-cell function resulting from chronic exposure to hyperglycemia. Recent prospective trials have suggested that an elevated level of C-reactive protein and gamma-glutamyl transferase enzyme is associated with subsequent development of diabetes. The present study aimed to examine the relationship between gamma-glutamyl transferase and the marker of inflammation C-reactive protein in patients with diabetes. The study was conducted on 300 patients, including 100 healthy controls and 200 patients with type 2 diabetes. Plasma glucose levels (fasting and postprandial), serum levels of high-sensitivity C-reactive protein, levels of glycosylated hemoglobin, and serum gamma-glutamyl transferase hepatic enzyme levels were measured. The mean high-sensitivity C-reactive protein and gamma-glutamyl transferase levels in patients with type 2 diabetes mellitus were significantly higher than the values in controls (P < 0.0010). Further, a significant positive correlation was observed between gamma-glutamyl transferase levels and high-sensitivity C-reactive protein levels in patients with type 2 diabetics (r = 0.312, P = 0.001). The increase in the levels of high-sensi","PeriodicalId":351803,"journal":{"name":"medical journal of islamic world academy of sciences","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122241686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. M. Şimşek, Semiha Solak Grassi̇e, C. Emre, Sümeyra Çetin Gevrek
{"title":"Relationship between Environmental Conditions and Nosocomial Infection Rates in Intensive Care Unit","authors":"E. M. Şimşek, Semiha Solak Grassi̇e, C. Emre, Sümeyra Çetin Gevrek","doi":"10.5505/IAS.2017.66742","DOIUrl":"https://doi.org/10.5505/IAS.2017.66742","url":null,"abstract":"Intensive care units (ICUs) are important departmants at the hospital for nosocomial infections. Although an ICU has 5%– 10% of the hospital beds, 25%–50% of the nosocomial infections originate from the ICU (1,2). Both ventilator-related pneumonia (VRP) and catheter-related urinary tract infections (CRUIs) are the most common infections in the ICU (3). Many risk factors are responsible for nosocomial infection in the ICU (1,4). Some of the risk factos are related to the patient, whereas the others are related to the external factors (1,4). It is known that improving the risk factors decreases the infection, mortality, morbidity, and cost (1,3).","PeriodicalId":351803,"journal":{"name":"medical journal of islamic world academy of sciences","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121810788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Complications of Infectious Mononucleosis in Children","authors":"M. Koçak, D. Güven","doi":"10.5505/ias.2020.83702","DOIUrl":"https://doi.org/10.5505/ias.2020.83702","url":null,"abstract":"","PeriodicalId":351803,"journal":{"name":"medical journal of islamic world academy of sciences","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121817645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of the Patients with Hyperprolactinemia","authors":"M. Ilhan, S. Turgut","doi":"10.5505/ias.2017.03708","DOIUrl":"https://doi.org/10.5505/ias.2017.03708","url":null,"abstract":"The frequency of hyperprolactinemia may vary according to the population studied. Various studies in the general population have reported the prevalence of 0.4%–17% (3). As expected, it is higher in endocrinology or gynecology outpatient clinics. The incidence of hyperprolactinemia can be as high as 9% in amenorrhoeic women, 25% in women with galactorrhea, 16%–30% in women with infertility, and 70% in women with both amenorrhea and galactorrhea (2, 4, 5). ABSTRACT Hyperprolactinemia is characterized by the elevation of prolactin levels in circulation. It is the most common disorder of the hypothalamic–pituitary axis. Proper evaluation of the etiology in these patients is extremely important for the accurate follow-up and treatment. This review study aimed to discuss differential diagnoses and key points in patients with hyperprolactinemia.","PeriodicalId":351803,"journal":{"name":"medical journal of islamic world academy of sciences","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116780955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Mahgoub, M. Y. Elkhalifa, K. A. Medani, W. Abdalla
{"title":"Mother’s Health Awareness and Nutritional Status of Children in Khartoum State-Sudan","authors":"A. Mahgoub, M. Y. Elkhalifa, K. A. Medani, W. Abdalla","doi":"10.12816/0008174","DOIUrl":"https://doi.org/10.12816/0008174","url":null,"abstract":"Family health is an essential matter. Mother plays a vital role concerning providing health care for her family. She bears the responsibility of taking care of her children’ 's health needs and caring for older adults or sick relatives (1). She is also responsible for their foods, hygienic measures and health requirement. The mother is also responsible for upbringing healthy infants and children as she take the decision regarding their health and illness. Many studies have shown that the most important factors affecting family health are mother’ s education, age, economic status, her knowledge and attitudes towards preventive measurement, treatment of diseases and how to promote health (2-5).","PeriodicalId":351803,"journal":{"name":"medical journal of islamic world academy of sciences","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122483491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antibacterial Potency of Aqueous Plant Extracts against Streptococcus Mutans","authors":"H. F. Akrayi","doi":"10.12816/0008177","DOIUrl":"https://doi.org/10.12816/0008177","url":null,"abstract":"","PeriodicalId":351803,"journal":{"name":"medical journal of islamic world academy of sciences","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131602761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Therapeutic Evaluation of Kalonji ( Nigella Sativa ) in Dyslipidemia - a Randomized Control Trial","authors":"A. Rasheed, M. A. Siddiqui, J. Khan","doi":"10.12816/0008181","DOIUrl":"https://doi.org/10.12816/0008181","url":null,"abstract":"","PeriodicalId":351803,"journal":{"name":"medical journal of islamic world academy of sciences","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127671315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is Helicobacter Pylori Infections in Immunocompromised Children a Risk Factor for Cancer","authors":"A. Amer, J. Hassan, I. Al-saimary","doi":"10.12816/0008169","DOIUrl":"https://doi.org/10.12816/0008169","url":null,"abstract":"Helicobacter pylori (H. pylori) has been classified as a carcinogenicpathogen (1). Its prevalence is high in developing countries. A part from the gastro-intestinal pathological changes caused by this organism, reports on the association between H. pylori infection and extra gastro-intestinal diseases have been increasing (2). Although impaired host immunity should be associated with a high prevalence of this infection, a definitive relationship has not been established. In this study a cross-sectional study had been conducted to determine the prevalence of H. pylori infection in immunocompromised Thailand children (3). From 2003 to 2004, a total of 60 children <18 years of age, who received corticosteroids, immunosuppressive drugs, or both, were enrolled consecutively into this study. Patients who had taken proton pump inhibitors and antimicrobial drugs 2 weeks before the study began were excluded. Stool specimens were collected and immediately stored at – 20° C before analysis with the H. pylori stool antigen test (4). Although no study has validated this test in Thai children, most studies report its high sensitivity and specificity (>90%).The study reported a significant relation of H. pylori and childhood cancer with 16.6% among children with cancer and only 3.3% among those without cancer (2,5). Helicobacter pylori infection seems to be associated with an increased risk of developing gastric cancer. However, only a small number of infected individuals will develop gastric cancer (6), including mucosa-associated lymphoid tissue lymphoma and adenocarcinoma. The infection is contracted primarily in childhood and infection from childhood appears to enhance the risk for carcinogenesis (7). In 1994 Helicobacter pylori was classified as a group 1 carcinogen for gastric cancer by the International Agency for Research on Cancer (1). The colonization with H. pylori determine the development of gastric atrophy, also called multifocal atrophic gastritis. This involves loss of gastric ABSTRACT","PeriodicalId":351803,"journal":{"name":"medical journal of islamic world academy of sciences","volume":"193 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132913396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahdi Nk, H. al-Abadi, L. Al-Naama, J. K. Mahdi, Murtadha Alawy
{"title":"The Role of Autoantibody and Antioxidant Enzymes in Patients with Type I Diabetes","authors":"Mahdi Nk, H. al-Abadi, L. Al-Naama, J. K. Mahdi, Murtadha Alawy","doi":"10.12816/0010266","DOIUrl":"https://doi.org/10.12816/0010266","url":null,"abstract":"This study included 80 individuals, 40 patients with type 1 diabetes and 40 healthy individuals without diabetes (as a control group). The study was carried out during the period from December 2010 to the end of December 2012 at Al-Tahreer General Hospital, Al-Basra Maternity and Pediatric Hospital, and Al-Sader Teaching Hospital. Laboratory investigations were performed to estimate glutamic acid decarboxylase antibody (GADA) and islet cell antigen-2 antibody (IA-2A) by enzyme-linked immunosorbent assay (ELISA), antioxidant enzymes (glutathione peroxidase [GPX] and superoxide dismutase [SOD]), and glycosylated hemoglobin (HbA1c) (as a marker of glycemic control) for these patient and control groups.","PeriodicalId":351803,"journal":{"name":"medical journal of islamic world academy of sciences","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131901287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}