Evaluation of the Patients with Hyperprolactinemia

The frequency of hyperprolactinemia may vary according to the population studied. Various studies in the general population have reported the prevalence of 0.4%–17% (3). As expected, it is higher in endocrinology or gynecology outpatient clinics. The incidence of hyperprolactinemia can be as high as 9% in amenorrhoeic women, 25% in women with galactorrhea, 16%–30% in women with infertility, and 70% in women with both amenorrhea and galactorrhea (2, 4, 5). ABSTRACT Hyperprolactinemia is characterized by the elevation of prolactin levels in circulation. It is the most common disorder of the hypothalamic–pituitary axis. Proper evaluation of the etiology in these patients is extremely important for the accurate follow-up and treatment. This review study aimed to discuss differential diagnoses and key points in patients with hyperprolactinemia.