The Role of Autoantibody and Antioxidant Enzymes in Patients with Type I Diabetes

Abstract

This study included 80 individuals, 40 patients with type 1 diabetes and 40 healthy individuals without diabetes (as a control group). The study was carried out during the period from December 2010 to the end of December 2012 at Al-Tahreer General Hospital, Al-Basra Maternity and Pediatric Hospital, and Al-Sader Teaching Hospital. Laboratory investigations were performed to estimate glutamic acid decarboxylase antibody (GADA) and islet cell antigen-2 antibody (IA-2A) by enzyme-linked immunosorbent assay (ELISA), antioxidant enzymes (glutathione peroxidase [GPX] and superoxide dismutase [SOD]), and glycosylated hemoglobin (HbA1c) (as a marker of glycemic control) for these patient and control groups.