Problems of Endocrinology最新文献_第3页

Morphological analysis of changes in the heart and aorta of rats undergoing bilateral ovariectomy; cardio- and vasoprotective effects of estradiol 双侧卵巢切除大鼠心脏及主动脉形态学变化分析雌二醇对心脏和血管的保护作用

Problems of Endocrinology Pub Date : 2019-09-23 DOI: 10.14341/probl199844235-39

A. N. Karachentsev, I. A. Melchenko

引用次数: 0

Evaluation of the effectiveness of chronocorrection of hemocoagulation and microcirculation by angioprotectors and antiplatelet agents of diabetic microangiopathy 血管保护剂和抗血小板药物对糖尿病微血管病变患者凝血微循环的时间矫正效果评价

Problems of Endocrinology Pub Date : 2019-09-23 DOI: 10.14341/probl199844212-13

E. Tulemisov, R. Zaslavskaya, L. Smirnova

{"title":"Evaluation of the effectiveness of chronocorrection of hemocoagulation and microcirculation by angioprotectors and antiplatelet agents of diabetic microangiopathy","authors":"E. Tulemisov, R. Zaslavskaya, L. Smirnova","doi":"10.14341/probl199844212-13","DOIUrl":"https://doi.org/10.14341/probl199844212-13","url":null,"abstract":"The efficacies of four protocols for treating patients with insulin-dependent diabetes mellitus (IDDM) and microangiopathies of the I and II degree are compared: traditional therapy with pro dectin (250 mg) and trental (100 mg) 3 times daily (17 patients), prodectin (250 mg) and aspirin (125 mg) 3 times a day (16 patients), chronotherapy with prodectin in a dose of 250 mg and trental in a dose of 100 mg once a day (17 patients), and prodectin (250 mg) and aspirin (125 mg) once a day 1.5-2 h before the acrophase of the circadian rhythm of blood coagulation, microcirculation, and peripheral hemodynamics parameters (16 patients). Before and 15-17 days after treatment, blood coagulation values were studied by the autocoagulation and hemolysate aggregation tests, measurements of blood fibrinogen, antithrombin III, soluble fibrin monomer complexes, and fibrinolytic activity of the blood; microcirculation was assessed by biomicroscopy of the eye conjunctiva, and peripheral hemodynamics by the radioactive xenome method and rheova- sography of the shin. The studies demonstrated a higher efficacy of chronotherapy in comparison with traditional prodectin in combination with trental and aspirin.","PeriodicalId":342539,"journal":{"name":"Problems of Endocrinology","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134008892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The optimal diagnostic complex in the surgical treatment of nodular euthyroid goiter 结节性甲状腺功能亢进手术治疗的最佳诊断复合体

Problems of Endocrinology Pub Date : 2019-09-23 DOI: 10.14341/probl199844214-19

Vetshev Ps, Kuznetsov Ns, Chilingaridi Ke, V. Vanushko, Ozerov Sk, Gabaidze Di

{"title":"The optimal diagnostic complex in the surgical treatment of nodular euthyroid goiter","authors":"Vetshev Ps, Kuznetsov Ns, Chilingaridi Ke, V. Vanushko, Ozerov Sk, Gabaidze Di","doi":"10.14341/probl199844214-19","DOIUrl":"https://doi.org/10.14341/probl199844214-19","url":null,"abstract":"Different methods for preoperative diagnosis of nodular euthyroid formations of the thyroid gland are compared. The sensitivity and specificity of ultrasonic examination (based on the study of the semeiotics of nodular formations of the thyroid), fine-needle aspiration biopsy (under palpation and ultrasonic control), and complex diagnosis (simultaneous assessment of ultrasonic semeiotics of the nodular formation and controlled biopsy under ultrasonic control followed by cytological examination of puncture biopsy specimens) are assessed. With this aim in view, 342 patients with nodular euthyroid formations were examine^ in 1994-1996. Benign nodular formations were detected in 316 (92.4%)) and thyroid cancer in 26 (7.6%o) patients. In the group with benign formations, colloid goiter was diagnosed in 204 (59.7%), follicular-cell adenomas in 78 (22.8%)), and hypertrophic autoimmune thyroiditis in 34 (9.9%) cases. The authors consider that ultrasonic examination combined with fine-needle aspiration biopsy is the most available, safe, and highly effective complex for the diagnosis of nodular euthyroid formations at the preoperative stage. Complex preoperative ultrasonic examination with fine-needle biopsy help single out the group with suspected malignant involvement of the thyroid with a high probability. Use of this complex and intraoperative ultrasonic examination correctly identified the type of thyroid involvement and its morphology in 92.4%o of cases, and thus helped choose adequate volume of intervention.","PeriodicalId":342539,"journal":{"name":"Problems of Endocrinology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130701554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The health status of children born to mothers with persistent galactorrhea syndrome - amenorrhea treated with parlodel 持续性乳溢综合征-闭经治疗母亲所生儿童的健康状况

Problems of Endocrinology Pub Date : 2019-09-23 DOI: 10.14341/probl199844239-42

O. Sudakova, E. V. Kurysheva, R. M. Kurlandskaya

引用次数: 0

The effect of normobaric hypoxia on the secretion of insulin and growth hormone 常压缺氧对胰岛素和生长激素分泌的影响

Problems of Endocrinology Pub Date : 2019-09-23 DOI: 10.14341/probl19984427-9

N. T. Starkova, A. Davydov, A. Koroleva

引用次数: 0

Serum prolactin binding in various forms of hyperprolactinemia 血清催乳素结合在各种形式的高催乳素血症

Problems of Endocrinology Pub Date : 2019-09-23 DOI: 10.14341/probl199844232-35

A. Bulatov, E. E. Makarovskaya, E. Marova

引用次数: 0

From the history of treatment of thyrotoxicosis with radioactive iodine in Russia 从俄罗斯放射性碘治疗甲状腺毒症的历史来看

Problems of Endocrinology Pub Date : 2019-09-23 DOI: 10.14341/probl199844254-54

V. Fadeev, N. D. Petrova

引用次数: 1

Adrenal incidentoma 肾上腺incidentoma

Problems of Endocrinology Pub Date : 2019-09-23 DOI: 10.14341/probl199844242-46

P. Vetshev, L. Ippolitov, V. A. Sinatulina

{"title":"Adrenal incidentoma","authors":"P. Vetshev, L. Ippolitov, V. A. Sinatulina","doi":"10.14341/probl199844242-46","DOIUrl":"https://doi.org/10.14341/probl199844242-46","url":null,"abstract":"Accidentally detected adrenal tumors, or the so-called incidentalomas or adrenalomas (from incidentally discovered adrenal mass), are a relatively new and insufficiently studied problem of endocrinology and endocrine surgery [18, 25, 43, 48, 56]. \u0000Issues related to the etiology, morphogenesis, diagnosis and tactics of treatment with incidental have been little studied and are not consolidated into a single integrated system. Several years ago in the periodical press there were few works devoted to this problem [18, 48], and the corresponding sections in the special manuals were extremely short or absent. For many years, hormone-inactive adrenal tumors were, as a rule, an accidental sectional finding [24, 32, 38, 53]. Only with the introduction into wide clinical practice of highly effective diagnostic technologies (ultrasound - ultrasound, computed tomography - CT, magnetic resonance imaging - MRI, selective angiography, etc.) did real possibilities for intravital diagnosis of these tumors appear, as evidenced by the steadily increasing number of publications [ 18, 19, 41, 48, 53, 58, 82]. However, at present, in most cases, incidentalomas are detected by chance during a comprehensive study of the abdominal organs, carried out for some other reason, not related to the pathology of the adrenal glands. Thus, most authors use the term “incidentaloma” to refer to an accidentally detected adrenal tumor [20, 22, 30, 41, 48, 53, 58].","PeriodicalId":342539,"journal":{"name":"Problems of Endocrinology","volume":"106 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126759576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endocrine ophthalmopathy 内分泌眼病

Problems of Endocrinology Pub Date : 2019-09-23 DOI: 10.14341/probl199844222-27

T. Pavlova, G. A. Kotova, G. A. Gerasimov

引用次数: 1

E. J. Pavlik, ed. Estrogens, progestins and their antagonists. - Vol. 2. Functions and mechanisms of action. - Boston, Basel, Berlin: Bikhauser, 1996 .-- 632 p. E. J. Pavlik主编。雌激素、孕激素及其拮抗剂。——第二卷功能和作用机制。-波士顿，巴塞尔，柏林:Bikhauser, 1996 .- 632页

Problems of Endocrinology Pub Date : 2019-09-23 DOI: 10.14341/probl199844253-54

L. Bershtein

{"title":"E. J. Pavlik, ed. Estrogens, progestins and their antagonists. - Vol. 2. Functions and mechanisms of action. - Boston, Basel, Berlin: Bikhauser, 1996 .-- 632 p.","authors":"L. Bershtein","doi":"10.14341/probl199844253-54","DOIUrl":"https://doi.org/10.14341/probl199844253-54","url":null,"abstract":"The book under review is part of a lengthy and interesting series for specialists, published by the Birkhauser Publishing House and having the common title Hormones in Normal and Pathological Conditions. The first volume of the book, a review of which is published in Issue 3 of the journal “Oncology Issues” for 1997, deals mainly with the degree of oncological risk of estrogen replacement therapy in menopause, about the not always unambiguous anticarcinogenic properties of phytoestrogens and food indoles, and about modern approaches to hormone therapy for prostate cancer, etc., i.e., mainly about the problems of oncological endocrinology. The 2nd volume of this publication, as its editor E. Pavlik writes in the introduction to the book, is devoted to the physiological and molecular mechanisms of action of estrogens, progestins and their antagonists, and is primarily focused on the discussion of the effect of various and often even opposite effects these compounds in different cells and tissues. A highly qualified team of authors, assembled by the editor, was able to ensure the implementation of this difficult and responsible task.","PeriodicalId":342539,"journal":{"name":"Problems of Endocrinology","volume":"104 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114977338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0