From the history of treatment of thyrotoxicosis with radioactive iodine in Russia

Abstract

The quantitative determination of the content of radioactive iodine in the urine for the evaluation of the functional state of the thyroid gland was first introduced into clinical practice by J. Hamilton in 1939, and in 1942 he developed a method for determining the content of radioactive iodine directly in the thyroid gland, and in the same year reported experiment on a dog who was injected with a large dose (300 μCi per 1 g of body weight) of radioactive 1311, which caused complete destruction of the thyroid gland with complete replacement of its structure with connective tissue with complete safety araschitovidnyh glands. By 1950, there were already many works devoted to this topic. In the mid-50s, such works began to appear in Russia. Among them, one can note the research of M. N. Fateeva (1953), V. K. Modestov (1958), A. 3. Tsfasman (1961), P. I. Egorov (1961), N M. Draznina (1961) and others, but this problem is most fully reflected in the domestic literature in the writings of prof. V. G. Spesivtseva [1-3].