IEEE Open Journal of Engineering in Medicine and Biology最新文献

{"title":"Advances in Electroencephalography for Post-Traumatic Stress Disorder Identification: A Scoping Review","authors":"José A. Salazar-Castro;Diego H. Peluffo-Ordóñez;Diego M. López","doi":"10.1109/OJEMB.2025.3538498","DOIUrl":"https://doi.org/10.1109/OJEMB.2025.3538498","url":null,"abstract":"<italic>Background:</i> Post-traumatic stress disorder (PTSD) is a psychophysiological condition caused by traumatic experiences. Its diagnosis typically relies on subjective tools like clinical interviews and self-reports. <italic>Objectives:</i> This scoping review analyzes computational methods using EEG signal processing for PTSD diagnosis, differentiation, and therapy. It provides a comprehensive overview of the entire EEG analysis pipeline, from acquisition to statistical and machine learning techniques for PTSD diagnosis. <italic>Methods:</i> Using the PRISMA-ScR protocol, studies published between 2013 and 2024 were reviewed from databases including Scopus, Web of Science, and PubMed. A total of 73 studies were analyzed: 52 on diagnosis, 8 on differentiation, and 15 on therapy. <italic>Results:</i> EEG Bands and Event-Related Potentials (ERP) were the dominant techniques. The Alpha band demonstrated strong performance in diagnosis and therapy. LPP ERP was most effective for diagnosis, and P300 for differentiation. Supervised SVM models achieved the highest accuracy in diagnosis (ACC = 0.997), differentiation (ACC = 0.841), and psychotherapy (ACC = 0.78). Random Forest multimodal models integrating EEG with other modalities (e.g., ECG, GSR, Speech) achieved ACC = 0.993. Unsupervised approach is employed to cluster patients to identify PTSD subtypes or to differentiate PTSD from other mental disorders. Veterans and combatants were the primary study population, and only three studies reported open datasets. <italic>Conclusions:</i> EEG-based methods hold promise as objective tools for PTSD diagnosis and therapy. The review identified limitations in the use of ERP, sleep characterization and full-band EEG. Broader datasets representing diverse populations are essential to mitigate bias and facilitate robust inter-model comparisons. Future research should focus on deep learning, adaptive signal decomposition, and multimodal approaches.","PeriodicalId":33825,"journal":{"name":"IEEE Open Journal of Engineering in Medicine and Biology","volume":"6 ","pages":"332-344"},"PeriodicalIF":2.7,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10874198","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2024 Index IEEE Open Journal of Engineering in Medicine and Biology Vol. 5","authors":"","doi":"10.1109/OJEMB.2025.3538256","DOIUrl":"https://doi.org/10.1109/OJEMB.2025.3538256","url":null,"abstract":"","PeriodicalId":33825,"journal":{"name":"IEEE Open Journal of Engineering in Medicine and Biology","volume":"5 ","pages":"885-909"},"PeriodicalIF":2.7,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10870393","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143106067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BandFocusNet: A Lightweight Model for Motor Imagery Classification of a Supernumerary Thumb in Virtual Reality","authors":"Haneen Alsuradi;Joseph Hong;Alireza Sarmadi;Robert Volcic;Hanan Salam;S. Farokh Atashzar;Farshad Khorrami;Mohamad Eid","doi":"10.1109/OJEMB.2025.3537760","DOIUrl":"https://doi.org/10.1109/OJEMB.2025.3537760","url":null,"abstract":"<italic>Objective:</i> Human movement augmentation through supernumerary effectors is an emerging field of research. However, controlling these effectors remains challenging due to issues with agency, control, and synchronizing movements with natural limbs. A promising control strategy for supernumerary effectors involves utilizing electroencephalography (EEG) through motor imagery (MI) functions. In this work, we investigate whether MI activity associated with a supernumerary effector could be reliably differentiated from that of a natural one, thus addressing the concern of concurrency. Twenty subjects were recruited to participate in a two-fold experiment in which they observed movements of natural and supernumerary thumbs, then engaged in MI of the observed movements, conducted in a virtual reality setting. <italic>Results:</i> A lightweight deep-learning model that accounts for the temporal, spatial and spectral nature of the EEG data is proposed and called BandFocusNet, achieving an average classification accuracy of 70.9% using the leave-one-subject-out cross validation method. The trustworthiness of the model is examined through explainability analysis, and influential regions-of-interests are cross-validated through event-related-spectral-perturbation (ERSPs) analysis. Explainability results showed the importance of the right and left frontal cortical regions, and ERSPs analysis showed an increase in the delta and theta powers in these regions during the MI of the natural thumb but not during the MI of the supernumerary thumb. <italic>Conclusion:</i> Evidence in the literature indicates that such activation is observed during the MI of natural effectors, and its absence could be interpreted as a lack of embodiment of the supernumerary thumb.","PeriodicalId":33825,"journal":{"name":"IEEE Open Journal of Engineering in Medicine and Biology","volume":"6 ","pages":"305-311"},"PeriodicalIF":2.7,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10869342","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143512945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enabling Model-Based Design for Real-Time Spike Detection","authors":"Mattia Di Florio;Yannick Bornat;Marta Carè;Vinicius Rosa Cota;Stefano Buccelli;Michela Chiappalone","doi":"10.1109/OJEMB.2025.3537768","DOIUrl":"https://doi.org/10.1109/OJEMB.2025.3537768","url":null,"abstract":"<italic>Goal</i>: This study addresses the inherent difficulties in the creation of neuroengineering devices for real-time neural signal processing, a task typically characterized by intricate and technically demanding processes. Beneath the substantial hardware advancements in neurotechnology, there is often rather complex low-level code that poses challenges in terms of development, documentation, and long-term maintenance. <italic>Methods</i>: We adopted an alternative strategy centered on Model-Based Design (MBD) to simplify the creation of neuroengineering systems and reduce the entry barriers. MBD offers distinct advantages by streamlining the design workflow, from modelling to implementation, thus facilitating the development of intricate systems. A spike detection algorithm has been implemented on a commercially available system based on a Field-Programmable Gate Array (FPGA) that combines neural probe electronics with configurable integrated circuit. The entire process of data handling and data processing was performed within the Simulink environment, with subsequent generation of hardware description language (HDL) code tailored to the FPGA hardware. <italic>Results</i>: The validation was conducted through in vivo experiments involving six animals and demonstrated the capability of our MBD-based real time processing (latency <=>Conclusions</i>: This methodology can have a significant impact in the development of neuroengineering systems by speeding up the prototyping of various system architectures. We have made all project code files open source, thereby providing free access to fellow scientists interested in the development of neuroengineering systems.","PeriodicalId":33825,"journal":{"name":"IEEE Open Journal of Engineering in Medicine and Biology","volume":"6 ","pages":"312-319"},"PeriodicalIF":2.7,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10870096","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143583136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound Segmentation Using Semi-Supervised Learning: Application in Point-of-Care Sarcopenia Assessment","authors":"Hamza Rasaee;Maryia Samuel;Bahareh Behboodi;Jonathan Afilalo;Hassan Rivaz","doi":"10.1109/OJEMB.2025.3537560","DOIUrl":"https://doi.org/10.1109/OJEMB.2025.3537560","url":null,"abstract":"Ultrasound imaging is crucial in medical diagnostics, offering real-time visualization of internal anatomical structures. However, accurate automatic segmentation of ultrasound images remains challenging, particularly in scenarios with limited labeled data. In this paper, we propose a semi-supervised learning approach for ultrasound image segmentation, leveraging the statistics of data in unlabeled images to enhance segmentation accuracy. Our method builds upon the encoder-decoder architecture and incorporates innovative semi-supervised learning techniques based on contrastive learning. We have collected ultrasound images from 80 patients and 34 healthy volunteers, focusing on applications in sarcopenia assessment and emergency response scenarios. We demonstrate the effectiveness of our approach through extensive experiments on expert segmentations in this dataset.Our results demonstrate the superior performance of the proposed method across various training data splits (i.e., 1%, 5%, 10%, 20%, 30%, and 100%). While U-NET performed the best with 100% of the training data (i.e., 154 annotated images), the proposed method achieved comparable performance with only 10% of the data (i.e., 16 annotated images). Furthermore, statistical analysis confirmed that our method significantly outperforms existing models, including U-NET, CCT, and UniMatch, in most scenarios (i.e., training set splits). These findings highlight the robustness and efficiency of the proposed method, especially in environments where labeled data is scarce","PeriodicalId":33825,"journal":{"name":"IEEE Open Journal of Engineering in Medicine and Biology","volume":"6 ","pages":"322-331"},"PeriodicalIF":2.7,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10869339","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low-Rank Adaptation of Pre-Trained Large Vision Models for Improved Lung Nodule Malignancy Classification","authors":"Benjamin P. Veasey;Amir A. Amini","doi":"10.1109/OJEMB.2025.3530841","DOIUrl":"https://doi.org/10.1109/OJEMB.2025.3530841","url":null,"abstract":"<italic>Goal:</i> This paper investigates using Low-Rank Adaptation (LoRA) to adapt large vision models (LVMs) pretrained with self-supervised learning (SSL) for lung nodule malignancy classification. Inspired by LoRA's success in the field of Natural Language Processing, we hypothesized that such an adaptation technique can significantly improve classification performance, parameter efficiency, and training speed for the novel application of lung image cancer diagnostic. <italic>Methods:</i> Utilizing two comprehensive lung nodule datasets, NLSTx and LIDC, which together encompass a diverse array of biopsy- and radiologist-confirmed lung CT scans, our rigorous experimental setup demonstrates that LoRA-adapted models markedly surpass traditional fine-tuning methods. <italic>Results:</i> The best LoRA-adapted model achieved a 3% increase in ROC AUC over the state-of-the-art model, utilized 89.9% fewer parameters, and reduced training times by 36.5%. <italic>Conclusions:</i> Integrating LoRA with out-of-domain pretrained LVMs offers a promising avenue for enhancing performance of lung nodule malignancy classification. The annotations for the NLSTx dataset are also released with this paper on GitHub at <uri>https://github.com/benVZ/NLSTx</uri>.","PeriodicalId":33825,"journal":{"name":"IEEE Open Journal of Engineering in Medicine and Biology","volume":"6 ","pages":"296-304"},"PeriodicalIF":2.7,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10843806","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143361179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review on Deep Learning for Quality of Life Assessment Through the Use of Wearable Data","authors":"Vasileios Skaramagkas;Ioannis Kyprakis;Georgia S. Karanasiou;Dimitris I. Fotiadis;Manolis Tsiknakis","doi":"10.1109/OJEMB.2025.3526457","DOIUrl":"https://doi.org/10.1109/OJEMB.2025.3526457","url":null,"abstract":"Quality of Life (QoL) assessment has evolved over time, encompassing diverse aspects of human existence beyond just health. This paper presents a comprehensive review of the integration of Deep Learning (DL) techniques in QoL assessment, focusing on the analysis of wearable data. QoL, as defined by the World Health Organisation, encompasses physical, mental, and social well-being, making it a multifaceted concept. Traditional QoL assessment methods, often reliant on subjective reports or informal questioning, face challenges in quantification and standardization. To address these challenges, DL, a branch of machine learning inspired by the human brain, has emerged as a promising tool. DL models can analyze vast and complex datasets, including patient-reported outcomes, medical images, and physiological signals, enabling a deeper understanding of factors influencing an individual's QoL. Notably, wearable sensory devices have gained prominence, offering real-time data on vital signs and enabling remote healthcare monitoring. This review critically examines DL's role in QoL assessment through the use of wearable data, with particular emphasis on the subdomains of physical and psychological well-being. By synthesizing current research and identifying knowledge gaps, this review provides valuable insights for researchers, clinicians, and policymakers aiming to enhance QoL assessment with DL. Ultimately, the paper contributes to the adoption of advanced technologies to improve the well-being and QoL of individuals from diverse backgrounds.","PeriodicalId":33825,"journal":{"name":"IEEE Open Journal of Engineering in Medicine and Biology","volume":"6 ","pages":"261-268"},"PeriodicalIF":2.7,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10841411","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143105936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Context-Aware Dual-Task Deep Network for Concurrent Bone Segmentation and Clinical Assessment to Enhance Shoulder Arthroplasty Preoperative planning","authors":"Luca Marsilio;Andrea Moglia;Alfonso Manzotti;Pietro Cerveri","doi":"10.1109/OJEMB.2025.3527877","DOIUrl":"https://doi.org/10.1109/OJEMB.2025.3527877","url":null,"abstract":"<italic>Goal:</i> Effective preoperative planning for shoulder joint replacement requires accurate glenohumeral joint (GH) digital surfaces and reliable clinical staging. <italic>Methods:</i> xCEL-UNet was designed as a dual-task deep network for humerus and scapula bone reconstruction in CT scans, and assessment of three GH joint clinical conditions, namely osteophyte size (OS), joint space reduction (JS), and humeroscapular alignment (HSA). <italic>Results:</i> Trained on a dataset of 571 patients, the model optimized segmentation and classification through transfer learning. It achieved median root mean squared errors of 0.31 and 0.24 mm, and Hausdorff distances of 2.35 and 3.28 mm for the humerus and scapula, respectively. Classification accuracy was 91 for OS, 93 for JS, and 85% for HSA. GradCAM-based activation maps validated the network's interpretability. <italic>Conclusions:</i> this framework delivers accurate 3D bone surface reconstructions and dependable clinical assessments of the GH joint, offering robust support for therapeutic decision-making in shoulder arthroplasty.","PeriodicalId":33825,"journal":{"name":"IEEE Open Journal of Engineering in Medicine and Biology","volume":"6 ","pages":"269-278"},"PeriodicalIF":2.7,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10835174","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143106057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remote Monitoring for the Management of Spasticity: Challenges, Opportunities and Proposed Technological Solution","authors":"Kavit R. Amin;Samuel R. Smith;Amit N. Pujari;Syed Ali Raza Zaidi;Robert Horne;Atif Shahzad;Christopher Walshaw;Christy Holland;Stephen Halpin;Rory J. O'Connor","doi":"10.1109/OJEMB.2024.3523442","DOIUrl":"https://doi.org/10.1109/OJEMB.2024.3523442","url":null,"abstract":"Spasticity is disabling feature of long-term neurological conditions that has substantial impact on people’ quality of life. Assessing spasticity and determining the efficacy of current treatments is limited by the measurement tools available in clinical practice. We convened an expert panel of clinicians and engineers to identify a solution to this urgent clinical need. We established that a reliable ambulatory spasticity monitoring system that collates clinically meaningful data remotely would be useful in the management of this complex condition. This paper provides an overview of current practices in managing and monitoring spasticity. Then, the paper describes how a remote monitoring system can help in managing spasticity and identifies challenges in development of such a system. Finally the paper proposes a monitoring system solution that exploits recent advancements in low-energy wearable systems comprising of printable electronics, a personal area network (PAN) to low power wide area networks (LPWAN) alongside back-end cloud infrastructure. The proposed technology will make an important contribution to patient care by allowing, for the first time, longitudinal monitoring of spasticity between clinical follow-up, and thus has life altering and cost-saving implications. This work in spasticity monitoring and management serves as an exemplar for other areas of rehabilitation.","PeriodicalId":33825,"journal":{"name":"IEEE Open Journal of Engineering in Medicine and Biology","volume":"6 ","pages":"279-286"},"PeriodicalIF":2.7,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10817570","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143105935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IEEE Engineering in Medicine and Biology Society Information","authors":"","doi":"10.1109/OJEMB.2024.3387891","DOIUrl":"https://doi.org/10.1109/OJEMB.2024.3387891","url":null,"abstract":"","PeriodicalId":33825,"journal":{"name":"IEEE Open Journal of Engineering in Medicine and Biology","volume":"5 ","pages":"C2-C2"},"PeriodicalIF":2.7,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10805082","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142843067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}