Acta Epileptologica最新文献_第2页

Arterial spin labeling perfusion MRI applications in drug-resistant epilepsy and epileptic emergency 动脉自旋标记灌注MRI在耐药癫痫和癫痫急症中的应用

Acta Epileptologica Pub Date : 2023-09-28 DOI: 10.1186/s42494-023-00134-3

Yingchun Xu, Ge Tan, Deng Chen, Jiao Liu, Zixian Zhou, Ling Liu

{"title":"Arterial spin labeling perfusion MRI applications in drug-resistant epilepsy and epileptic emergency","authors":"Yingchun Xu, Ge Tan, Deng Chen, Jiao Liu, Zixian Zhou, Ling Liu","doi":"10.1186/s42494-023-00134-3","DOIUrl":"https://doi.org/10.1186/s42494-023-00134-3","url":null,"abstract":"Abstract Epilepsy affects all age groups and is one of the most common and disabling neurological disorders worldwide. Drug-resistant epilepsy (DRE), status epilepticus (SE), and sudden unexpected death in epilepsy (SUDEP), which are associated with considerable healthcare costs and mortality, have always been difficult to address and become the focus of clinical research. The rapid identification of seizure onset and accurate localization of epileptic foci are crucial for the treatment and prognosis of people with DRE, SE, or near-SUDEP. However, most of the conventional neuroimaging techniques for assessing cerebral blood flow of people with epilepsy are restricted by time consumption, limited resolution, and ionizing radiation. Arterial spin labeling (ASL) is a newly powerful non-contrast magnetic resonance imaging technique that enables the quantitative evaluation of brain perfusion, characterized by its unique advantages of reproducibility and easy accessibility. Recent studies have demonstrated the potential advantages of ASL for the diagnosis and evaluation of epilepsy. Therefore, in this review, we discussed the complementary value of ASL in evaluating and characterizing the basic substrates underlying refractory epilepsy and epileptic emergencies.","PeriodicalId":33628,"journal":{"name":"Acta Epileptologica","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135387423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Absence seizures in lesion-related epilepsy 病变相关性癫痫的失神发作

Acta Epileptologica Pub Date : 2023-09-13 DOI: 10.1186/s42494-023-00133-4

Xiaoqin Sun, Miao Wang, Zeng He, Lihong Liu, Xianjun Shi, Chunqing Zhang, Ning An, Meihua Yang, Zhifeng Wu, Ruodan Wang, Li Wang, Zhongke Wang, Hui Yang, Xiaolin Yang, Shiyong Liu

{"title":"Absence seizures in lesion-related epilepsy","authors":"Xiaoqin Sun, Miao Wang, Zeng He, Lihong Liu, Xianjun Shi, Chunqing Zhang, Ning An, Meihua Yang, Zhifeng Wu, Ruodan Wang, Li Wang, Zhongke Wang, Hui Yang, Xiaolin Yang, Shiyong Liu","doi":"10.1186/s42494-023-00133-4","DOIUrl":"https://doi.org/10.1186/s42494-023-00133-4","url":null,"abstract":"Abstract Background In the new International League Against Epilepsy (ILAE) classification of seizure types, generalized seizures such as absence seizures (ASs) may originate from a focal point and rapidly spread to the bilaterally distributed brain network. Increasing evidence from animal and clinical studies has indicated that focal changes may occur prior to ASs; however, the relationship of ASs with epileptogenic lesions remains unclear. Methods We retrospectively collected and analyzed the clinical, imaging, and electrophysiological data of 16 patients who had ASs and structural lesions with seizure-free outcomes after lesion resection. Results In semiology analysis, nine patients displayed focal onset; only two patients showed simple ASs, and seizure types other than ASs were observed in the remaining patients. On ictal electroencephalography (EEG), four patients showed bilateral synchronous symmetric 3 Hz generalized spike-wave discharges (GSWDs), and the remaining patients showed bilateral 1.5–2.5 Hz GSWDs. Moreover, most patients (13/16, 81.3%) exhibited focal features in addition to ASs, while interictal EEG was the same in 12 patients. Furthermore, on stereoelectroencephalogram (SEEG), 2/5 patients showed focal discharges before bilateral burst GSWDs. Additionally, all patients had structural lesions on imaging. In four typical AS patients, the lesions were located in deep brain regions. Notably, in 9 patients (9/16, 56%), the lesions were located in the posterior cortex. All patients underwent lesion resection and had seizure-free outcomes during follow-up, and intelligence quotient (IQ) also improved by 10.71 ± 3.90 one year after surgery. Conclusions Patients with lesion-related epilepsy may present with ASs that have a focal onset and are associated with good surgical outcomes.","PeriodicalId":33628,"journal":{"name":"Acta Epileptologica","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135733688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heterogeneity of clinical features, EEG and brain imaging findings in anti-leucine-rich glioma-inactivated protein 1 autoimmune encephalitis: a retrospective case series study and review of the literature 抗富亮氨酸胶质瘤失活蛋白1自身免疫性脑炎的临床特征、脑电图和脑成像结果的异质性:回顾性病例系列研究和文献综述

Acta Epileptologica Pub Date : 2023-08-15 DOI: 10.1186/s42494-023-00132-5

Emily Yixuan Huang, Hongfeng Gao, N. Zhong

引用次数: 0

Consensus on pediatric epilepsy surgery for young children: an investigation by the China Association Against Epilepsy task force on epilepsy surgery 幼儿小儿癫痫手术共识:中国抗癫痫协会癫痫手术专案组调查

Acta Epileptologica Pub Date : 2023-08-14 DOI: 10.1186/s42494-023-00130-7

L. Cai, Kai Zhang, Wenjing Zhou, Xiaoqiu Shao, Y. Guan, Tao Yu, Ye Wu, Shuhua Chen, Rui Zhao, Shuli Liang, Xun Wu, G. Luan, Yuwu Jiang, Jianguo Zhang, Xiaoyan Liu

引用次数: 0

Development from recurrent anti-N-methyl-D-aspartate receptor encephalitis with seizures as the first symptom to autoimmune-associated epilepsy: a case report 从以发作为首发症状的复发性抗n -甲基- d -天冬氨酸受体脑炎发展到自身免疫相关癫痫:1例报告

Acta Epileptologica Pub Date : 2023-07-26 DOI: 10.1186/s42494-023-00129-0

Ningxiang Qin, Jing Wang, Xi Peng, Liang-yu Wang

引用次数: 0

Brief potentially ictal rhythmic discharges on intraoperative electrocorticography predict a good outcome of focal cortical dysplasia after surgical resection: a case report 术中皮质电图上短暂的潜在的节律性放电预测手术切除后局灶性皮质发育不良的良好结果:一个病例报告

Acta Epileptologica Pub Date : 2023-07-18 DOI: 10.1186/s42494-023-00131-6

Sofía S. Sánchez-Boluarte, W. Aguirre-Quispe, Manuel Herrera Aramburú, W. Tatum, Walter F. De La Cruz Ramirez

引用次数: 2

Emerging personalized virtual brain models: next-generation resection neurosurgery for drug-resistant epilepsy? 新兴的个性化虚拟脑模型:耐药癫痫的新一代切除神经外科?

Acta Epileptologica Pub Date : 2023-07-07 DOI: 10.1186/s42494-023-00128-1

Qiao Wang, Guangyu Jin, Tao Yu, F. Bartolomei, L. Ren