Nurachmawati Meindah Sari, R. Azizah, L. Sulistyorini, E. P. L. Emanuel, Emillia Devi Dwi Rianti, Fuad Ama, S. Sahadewa, Agusniar Furkani Listyawati, Ayly Soekanto, Hardiyono Hardiyono
{"title":"Dispersion of Carbon Monoxide Pollutant and The Effect of Health (Case Study on Frontage Road Surabaya by Gaussian Line Source Equation Model)","authors":"Nurachmawati Meindah Sari, R. Azizah, L. Sulistyorini, E. P. L. Emanuel, Emillia Devi Dwi Rianti, Fuad Ama, S. Sahadewa, Agusniar Furkani Listyawati, Ayly Soekanto, Hardiyono Hardiyono","doi":"10.30742/jikw.v11i2.2416","DOIUrl":"https://doi.org/10.30742/jikw.v11i2.2416","url":null,"abstract":"Air pollution was being a very important problem and danger for human life. This was related to diseases that arise due to motor vehicle emissions, especially carbon monoxide. Simulation of air dispersion models is the one way to study about air quality that is needed in this regard. This study aims to determine the distribution of carbon monoxide pollutants in Ahmad Yani's frontage and to anticipate the dangers of these pollutants to the health of the people living around the research location. This research discussed about the mathematical model of the dispersion of CO that emitted from cars that passed through the frontage road on the Ahmad Yani Street, Surabaya. The method used is direct observation in the field and numerical simulation using a mathematical model, Gaussian Line Source Equation Model (GLSEM). GLSEM had prepared based on the mechanism of transport of pollutants in dispersion, diffusion and advection. With GLSEM we calculated CO gas concentration values for certain heights downwind. We validated the model by comparing numerical results and measurements of CO concentration. We used the R2 test and we got an R2 close to one. We simulated GLSEM by used Fortran programming language and visualized it with Surfer. The results of the visualization in June showed that the pattern of CO gas dispersion was influenced by the direction and speed of the wind. The results obtained are that the distribution of CO pollutants in the Ahmad Yani frontage is horizontal/downwind. CO concentrations at night are higher than during the daytime. From the CO dispersion pattern, we had known that there were dangerous of air around the frontage for people health. We conclude that around the frontage road of the Ahmad Yani highway there is sufficient open air space so that the danger of CO pollutants being emitted can be minimized so that the health of the community, namely pedestrians, motorcycle drivers and the community around the location can be protected.","PeriodicalId":33090,"journal":{"name":"Jurnal Ilmiah Kedokteran Wijaya Kusuma","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76424896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. M. S. Harsa, Andiani Andiani, Harsono Wiradinata, Putu Oky Ari Tania
{"title":"Potency of Ethanol Extract Celery (Apium graveolens L.) Stalk as Anti-Cholesterol","authors":"I. M. S. Harsa, Andiani Andiani, Harsono Wiradinata, Putu Oky Ari Tania","doi":"10.30742/jikw.v11i2.2014","DOIUrl":"https://doi.org/10.30742/jikw.v11i2.2014","url":null,"abstract":"Increasing levels of blood cholesterol is one of the risk factors for atherosclerosis. Currently, experts have been trying used herbal medicine as an alternative treatment of atherosclerosis. One of the highlights is the use of celery stalks. Celery is generally used as a flavouring dish. In addition, celery stalks are believed able to reduce cholesterol levels because they contain flavonoids, tannins, and saponins. This study was aim to determine the effect of celery stalk ethanol extract to reduce LDL an increase of HDL level in rats after fed high-fat diet. Randomized Post Test Only Control Group Design was used to measure the HDL and LDL blood serum levels of male Wistar (Rattus norvegicus) rats fed a high-fat diet. This study was used 27 male Wistar rats (Rattus norvegicus) divided into 3 groups; K1 was only given regular feed and water, K2 was given a high-fat diet and water, K3 was given a high-fat diet and celery stalk extract at a dose of 75mg/kg BW/day for 14 days. The data were analysed by ANOVA test and Tukey HSD test. The results of the ANOVA test showed a significance value of p-value of LDL = 0.000 and HDL p-value = 0.536. Celery stalk extract (Apium graviolens L) had an effect on decreasing LDL levels but not on increasing HDL blood serum levels of white Wistar rats (Rattus norvegicus) given high-fat diet.","PeriodicalId":33090,"journal":{"name":"Jurnal Ilmiah Kedokteran Wijaya Kusuma","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74849116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Setiawan, Fetriyuna Fetriyuna, S. M. A. Letsoin, R. Purwestri, I. Jati
{"title":"A Sago Positive Character: A Literature Review","authors":"B. Setiawan, Fetriyuna Fetriyuna, S. M. A. Letsoin, R. Purwestri, I. Jati","doi":"10.30742/jikw.v11i2.2443","DOIUrl":"https://doi.org/10.30742/jikw.v11i2.2443","url":null,"abstract":"Sago is a carbohydrate-rich food that contains resistant starch. In some parts of Indonesia, Malaysia, and Papua New Guinea, sago is a common staple food. Studies have been performed to elucidate the physicochemical and structural properties of sago starches. The paper's objective is to review potential positive physiological responses to sago-based product consumption from previous records. This study is a literature review of preceding published articles related to sago intake in human subjects’ research. The literature search was performed through databases with assigned keywords combination and then selection of the articles based on the criteria. The outcomes of this review concluded that sago had a lower glycemic index with immediate intestinal absorption. Sago-based products could provide a suitable energy source for sustaining physical performance and promoting faster recovery after exercise. It can be an appropriate alternative as an energy source for active healthy individuals.","PeriodicalId":33090,"journal":{"name":"Jurnal Ilmiah Kedokteran Wijaya Kusuma","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84103797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zahratul Noreisza Rakhmadi, E. Yatmasari, P. Utami
{"title":"Literature Study: The Effect of Giving Chitosan Water Gel (Hydrogel) on Healing Diabetic Ulcers Based on In Vivo Studies with Animal Models","authors":"Zahratul Noreisza Rakhmadi, E. Yatmasari, P. Utami","doi":"10.30742/jikw.v11i2.1957","DOIUrl":"https://doi.org/10.30742/jikw.v11i2.1957","url":null,"abstract":"Diabetic ulcers are one of the most common chronic complications and cause infection, gangrene to leg amputation if the treatment given is not appropriate. Chitosan has anti-microbial properties that make the wound area smaller and are anti-inflammatory to reduce pain. Water gel (hydrogel), which is water, is easily absorbed by the skin and penetrates perfectly into the wound so that it provides a moist effect and prevents bacteria from entering. This study aims to determine the effect of giving chitosan water gel (hydrogel) on the healing of diabetic ulcers. This study uses a literature study method by searching for related journals using keywords, then selected based on the last 5 years and indexed in SINTA, Google Scholar or Scopus, and the final results are 13 journals. This study took place in May - November 2021. The results of this study reported that the administration of chitosan water gel (hydrogel) combined with other ingredients for healing diabetic ulcers gave the same results. The results obtained are reducing inflammation, re-epithelializing wounds, accelerating angiogenesis, accelerating the formation of collagen and granulation tissue, and accelerating wound healing. Although all studies have the same results, the healing time produced by each study is different, this is because each ingredient used has a different content. The average wound changes were seen on the 3rd, 5th, 7th day and the wound healed completely on the 14th day. This study concludes that the administration of chitosan water gel (hydrogel) affects the healing of diabetic ulcer wounds in combination with other ingredients. because the time needed to close the wound is faster.","PeriodicalId":33090,"journal":{"name":"Jurnal Ilmiah Kedokteran Wijaya Kusuma","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90643868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Florencia Christofora Ngantung, B. Supartono, Hikmah Muktamiroh
{"title":"The Role of Cytokines in Inflammatory Process of Knee Osteoarthritis: Systematic Review","authors":"Florencia Christofora Ngantung, B. Supartono, Hikmah Muktamiroh","doi":"10.30742/jikw.v11i2.2444","DOIUrl":"https://doi.org/10.30742/jikw.v11i2.2444","url":null,"abstract":"Osteoarthritis (OA) is a degenerative joint disorder that occurs in cartilage. OA is the main cause of disability in adults and generally characterized by pain to the joints that got pressured. Based on several previous studies, it is known that the incidence of osteoarthritis is correlated with synovial inflammation and that inflammatory cytokines play an important role in the expansion of osteoarthritis. Based on these things, the author intends to conduct a literature study with the aim of knowing the role of cytokines on inflammation in knee osteoarthritis. The research was conducted through PubMed and Science Direct databases. The results of the study showed that cytokines played negative different roles depending on the type of cytokines such as those found in knee OA inflammation. Conclusion: Cytokines have a negative effect because they can disrupt synovial tissue balance, induce catabolic processes, and induce osteoclast differentiation and subchondral bone resorption.","PeriodicalId":33090,"journal":{"name":"Jurnal Ilmiah Kedokteran Wijaya Kusuma","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85212259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arif Kusumo Rahardjo, Yusuf Hermawan, Vita Dwi Wijayanti
{"title":"Peritoneal Shunt Extraction in Children Using Laparoscopy: A Case Report","authors":"Arif Kusumo Rahardjo, Yusuf Hermawan, Vita Dwi Wijayanti","doi":"10.30742/jikw.v11i2.1488","DOIUrl":"https://doi.org/10.30742/jikw.v11i2.1488","url":null,"abstract":"Laparoscopy is one way to perform various simple procedures or surgeries in the abdominal cavity. Laparoscopy can be useful in the management of ventriculo-peritoneal shunt (VP Shunt) fractures. The peritoneal component of the shunt remaining in the abdominal cavity can be removed using laparoscopy. A pediatric patient with hydrocephalus with a history of VP Shunt insertion 5 years ago, came with complaints of weakness, vomiting and difficulty eating. Physical examination revealed the presence of edema in the chamber area. A CT scan of the head and plain abdominal radiographs were performed. The diagnosis was made as a shunt fracture, with the peritoneal component of the shunt remaining in the abdominal cavity. The patient received treatment in the form of a revised VP shunt and peritoneal shunt extraction using standard laparoscopy which is commonly used for adult patients. The patient's condition improved after the procedure. Peritoneal shunt extraction in cases of VP shunt fracture can be safely performed using laparoscopy. If there are limited tools, this procedure can still be performed on children using standard laparoscopy which is usually used for adult patients. Authors report this case due to no previous report in Mojokerto area were known.","PeriodicalId":33090,"journal":{"name":"Jurnal Ilmiah Kedokteran Wijaya Kusuma","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90656113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Effect of Patin Fish Oil Extract on LDL Cholesterol Levels Rattus norvegicus was Induced by Alloxan","authors":"Salsabila Yumna Fathony, Fitri Handajani, Indri Ngesti Rahayu","doi":"10.30742/jikw.v11i2.1877","DOIUrl":"https://doi.org/10.30742/jikw.v11i2.1877","url":null,"abstract":"Diabetes mellitus is a chronic hyperglycemic syndrome that can be accompanied by lipid metabolism disorders. Alloxan is a diabetogenic agent that is associated with an increase in LDL cholesterol levels. Patin fish contain omega-3 and oleic acid, which can potentially reduce or control LDL cholesterol levels. This study aims to determine the effect of Patin fish (Pangasius hypothalmus) oil extract on LDL cholesterol levels of alloxan-induced Rattus norvegicus. The method of this study is the post-test-only control group design. Twenty-seven experimental animals were divided into 3 groups; (1) the 1st group was without treatment, (2) 2nd group was induced with 150 mg/kg BW alloxan on the 7th day; (3) 3rd group was induced with 150 mg/kg BW alloxan on the 7th day and given the Patin fish oil extract at a dose of 73 mg/kg BW on the 10th day for 14 days. Blood samples were taken on the 24th day to determine LDL cholesterol levels. The results of the One-Way ANOVA test showed a significant mean difference, p=0,001 (p<a). The results of the Post-Hoc LSD test showed a meant difference between the 1st group and the 2nd control group p=0,001 (p<a); 2nd group and 3rd group p=0,026 (p<a); between the 1st group and the 3rd group p=0,015 (p<a). Giving alloxan 150 mg/kg BW can significantly increase LDL cholesterol levels of Rattus norvegicus and administration of Patin fish oil extract 73 mg/kg BW can significantly reduce LDL cholesterol levels of Rattus norvegicus.","PeriodicalId":33090,"journal":{"name":"Jurnal Ilmiah Kedokteran Wijaya Kusuma","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72826526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pengaruh Serbuk Daun Kelor (Moringa oleifera) Terhadap Apoptosis Sel Hepar Pada Tikus Bunting Diabetes Mellitus","authors":"H. K. Gondo","doi":"10.30742/jikw.v11i1.1650","DOIUrl":"https://doi.org/10.30742/jikw.v11i1.1650","url":null,"abstract":"Maternal death rate in Indonesia are still very high. One of the causes is gestasional diabetes mellitus during pregnancy. Some of healing efforts are done, one of them was utilization of plants, in this case, Moringa oleifera. The purpose of this reseach is to know the Moringa oleifera leaf powder on the pregnant wistar rats with gestasional diabetes mellitus. The study design was laboratoric experimental on the wistar rats as the experimental animal, using Control Group Post Test Design on the research. Sample was divided into 2 positive and negative control groups and 4 treatment groups given Moringa oleifera leaf powder that will be induced by alloxan and the liver histopatological result be examined. Total average of liver cell nucleus that goes through apoptosis is lower linear with the increase of the Moringa oleifera leaf powder dose given to the treatment group. After the alloxan induction, the wistar rats’ blood glucose level is increased, caused by the destruction of the beta cell pancreas. There’s a significant difference between the liver cell that go through apoptosis between the four treatment group of wistar rats. The total average of liver cell that go through apoptosis is lower linear with the increase of the Moringa oleifera leaf powder dose given to the treatment group. Oral administration of Moringa leaf powder to white rats with diabetes mellitus was able to improve the histopathological picture of the liver where the brown color was seen to decrease while the methylene green increased. As well as lowering the blood glucose levels of the rats.","PeriodicalId":33090,"journal":{"name":"Jurnal Ilmiah Kedokteran Wijaya Kusuma","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80617746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Albertus Medianto Walujo, I. G. A. S. Putra, I. W. Widana, Ida Ayu Ratih Wulansari Manuaba
{"title":"Nasotracheal Intubation under Videolaryngoscopy in Mandibular Abscess with Trismus","authors":"Albertus Medianto Walujo, I. G. A. S. Putra, I. W. Widana, Ida Ayu Ratih Wulansari Manuaba","doi":"10.30742/jikw.v11i1.1570","DOIUrl":"https://doi.org/10.30742/jikw.v11i1.1570","url":null,"abstract":"Management of a difficult airway is a challenge for every anesthesiologist. Mandibular stiffness, trismus, and facial structural deformities often limit the available airway management options. With a variety of techniques that have been developed today, the management of difficult airways is more optimal than conventional management. One technique that can be used is video laryngoscopy. The authors report a case of nasotracheal intubation by video laryngoscopy in a mandibular abscess patient with trismus. The purpose of this case report is to demonstrate the effectiveness of the video laryngoscopy technique to assist nasotracheal intubation and to add insight for nasotracheal intubation technique in difficult airway conditions, especially trismus. Female, 60-year-old, come with a left mandibular abscess with complicated trismus who was planned for incision and drainage of the abscess. Nasotracheal intubation was performed under video laryngoscopy and during the surgical procedure the patient's vital signs were stable. This case report concludes that video laryngoscopy can be an alternative to conventional techniques and awake fiberoptic intubation in the case of nasotracheal intubation.","PeriodicalId":33090,"journal":{"name":"Jurnal Ilmiah Kedokteran Wijaya Kusuma","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88470474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Characteristics of Indonesian Wild honey and Cultivited Honey and Their Antibacterial Activity against Staphylococcus aureus and Escherichia coli","authors":"Lusiani Tjandra, Budhiman Setyawan, Masfufatun Masfufatun","doi":"10.30742/jikw.v11i1.1795","DOIUrl":"https://doi.org/10.30742/jikw.v11i1.1795","url":null,"abstract":"Indonesia's natural wealth is very abundant in the form of flora and fauna that can be developed as raw materials for medicine. Honey in Indonesia is very diverse from Sabang to Merauke. Different types of honey are influenced by regional origin, season at harvest, type of bee, type of plant source of nectar, way of life of bees (cultivated or wild), harvesting method and post-harvest handling. This study aims to determine the characteristics of forest bee honey and cultivated honey and to determine the potential of honey as an antibacterial in the treatment of infectious diseases caused by Staphylococcus aureus and Escherichia Coli bacteria. The materials used were Carisa honey samples from Wild honey [Wild Klanceng and Wild Cerana] and Cultivation [Cerana Cultivation], S. aureus and E. coli bacteria. The characteristic test method is in accordance with the Indonesian National Standard and the honey inhibition test against the growth of S. aureus and E. Coli bacteria using the diffusion method. The results showed that Wild Cerana (WC) and Wild Klanceng (WK) honey demonstrated higher water content, ash content, acidity and glucose from Cerana Cultivated (CC) honey. Carissa Honey (beside Cerana cultivated honey) had antibacterial activity against S. aureus and E. Coli at different concentrations. Wild Wild Honey has the highest antibacterial activity compared to other types of honey. Conclusion Indonesian wild honey showed weak antibacterial activity against Staphylococcus aureus. Meanwhile, honey that is cultivated does not have antibacterial activity. ","PeriodicalId":33090,"journal":{"name":"Jurnal Ilmiah Kedokteran Wijaya Kusuma","volume":"1107 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76757277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}