Avicenna Journal of Medicine最新文献

{"title":"Surgical Intervention for Isolated Tricuspid Valve Endocarditis-Refining Patients' Selection.","authors":"Ali Hage, Rami Abazid, Fadi Hage, Shevan Bladia, Linrui Guo, Nikolaos Tzemos","doi":"10.1055/s-0045-1808059","DOIUrl":"10.1055/s-0045-1808059","url":null,"abstract":"<p><strong>Background: </strong>In this study, we analyzed various clinical and imaging factors of patients with isolated tricuspid valve infective endocarditis (TVIE) who have undergone surgical intervention, and assessed short- and long-term outcomes after surgery.</p><p><strong>Methods: </strong>We retrospectively enrolled 26 patients diagnosed with definite isolated TVIE and underwent surgical intervention between February 2004 and August 2019. We collected patients' demographics, preoperative and postoperative data. The primary outcomes were death and a composite of the following: death, readmission with right-sided heart failure, or recurrent endocarditis.</p><p><strong>Results: </strong>A total of 29 isolated tricuspid valve surgical interventions were performed on 26 patients. The mean age was 38.6 ± 12.3 years. In total, 22/29 (75.8%) of TVIE were related to <i>Staphylococcus aureus</i> and 4/29 (13.8%) were secondary to fungal infection. During a follow-up of 5.4 ± 3.7 years, there were 9 (34.6%) deaths and 15 (57.7%) composite outcomes. Multivariable Cox regression analysis showed that male sex (hazard ratio [HR]: 16.68, 95% confidence interval [CI]: 1.63-170.34, <i>p</i>  = 0.018) and intravenous drug users (IVDU) (HR: 25.66, 95% CI: 1.87-352.79, <i>p</i>  = 0.015) are significantly associated with increase death; on the other hand, higher level of preoperative hemoglobin and preoperative left ventricular ejection fraction (LVEF) was found to have decreased hazard of death: HR: 0.90, 95% CI: 0.82-0.99, <i>p</i>  = 0.033 and HR: 0.92, 95% CI: 0.86-0.98, <i>p</i>  = 0.013, respectively.</p><p><strong>Conclusion: </strong>In our institution, surgical intervention for isolated TVIE has a mortality rate of 34.6%. Men, a history of IVDU, lower preoperative hemoglobin levels, and reduced LVEF were significant predictors of postsurgical mortality. Earlier surgical intervention for TVIE before the development of anemia or impaired LV systolic function may have a potential survival benefit.</p>","PeriodicalId":32889,"journal":{"name":"Avicenna Journal of Medicine","volume":"15 2","pages":"74-79"},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178669/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addressing the Critical Gap in Biological Therapies for Inflammatory Bowel Disease in Syria.","authors":"Marouf Mouhammad Alhalabi","doi":"10.1055/s-0045-1809039","DOIUrl":"10.1055/s-0045-1809039","url":null,"abstract":"","PeriodicalId":32889,"journal":{"name":"Avicenna Journal of Medicine","volume":"15 2","pages":"92-93"},"PeriodicalIF":0.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast Cancer Diagnosis and Management in an Area of Protracted Conflict: A Case Series from Northwest Syria.","authors":"Mohamed Hamze, Jude Alawa, Fares Alahdab, Alaa Al-Shemali, Ahmed Najeb Alhussein, Nour Muhammed Ali Arab, Bayan Galal, Jamil Debel, Ayham Jemo, Molham Khalil, Anees Chagpar, Bassel Atassi, Kaveh Khoshnood, Aula Abbara","doi":"10.1055/s-0045-1802585","DOIUrl":"10.1055/s-0045-1802585","url":null,"abstract":"<p><p><b>Background</b>  Breast cancer remains a significant public health challenge in conflict-affected regions. This study aims to investigate the impact of armed conflict on the burden of breast cancer in female patients in northwest Syria, focusing on clinical presentations, management, diagnosis, access to care, and treatment outcomes. <b>Methods</b>  We conducted a retrospective analysis of breast cancer patients diagnosed at the Idlib Oncology Center between March 2017 and January 2022. Data were extracted from clinical files and analyzed in R. The study was conducted at the Idlib Oncology Center, the main referral center for cancer care in northwest Syria, serving a population of 4.6 million. <b>Results</b>  A total of 192 patients were included, with a median age of 45.5 years (interquartile range [IQR]: 40-56). Of 108 patients, 56.5% were internally displaced. Most patients were diagnosed with invasive ductal carcinoma (81.3%), and the majority presented at stages II and III (34.8 and 59%, respectively). Among 192 patients, 95.8% underwent surgery, with 96.6% having a mastectomy and 90.7% receiving chemotherapy. The median interval from symptom onset to diagnosis was 100.5 days, that from diagnosis to surgery was 14.5 days, and that from surgery to radiotherapy was 229 days. No significant effect was observed for chemical weapon exposure or family loss on survival. Displacement was associated with significantly lower predicted survival ( <i>p</i>  = 0.0038; 95% confidence interval [CI]: 0.05064-0.2570). <b>Conclusions</b>  This study highlights a high prevalence of late-stage breast cancer, a high rate of mastectomies, delayed access to radiotherapy, and long delays between diagnosis and treatment in northwest Syria. Displacement negatively affects survival rates. Additionally, the substantial lack of radiotherapy in patients needing it and prolonged intervals between treatments contribute to poorer outcomes. Establishing localized oncology services and increasing funding for cancer medications and radiotherapy would improve access to necessary oncology care in this region.</p>","PeriodicalId":32889,"journal":{"name":"Avicenna Journal of Medicine","volume":"15 1","pages":"9-16"},"PeriodicalIF":0.0,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12088791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced Recovery after Pediatric Cardiac Surgery: A Meta-Analysis.","authors":"Osama Abu-Shawer, Abdel-Rahman E'mar, Abdel-Rahman Jaber, Shatha Tailakh, Amer Abu-Shawer, Caroline Al-Haddadin","doi":"10.1055/s-0045-1808072","DOIUrl":"10.1055/s-0045-1808072","url":null,"abstract":"<p><strong>Background: </strong>The Enhanced Recovery After Surgery (ERAS) protocols are a set of steps taken before, during, and after surgery to improve patient care and outcomes. While ERAS is well known for its benefits in various surgeries, its application in pediatric cardiac surgery is relatively new. With the recent emergence of studies on its implementation in pediatric cardiac surgery, this study is the first to systematically review the current evidence on the efficacy of ERAS in the field.</p><p><strong>Methods: </strong>A meta-analysis was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Two reviewers independently searched PubMed, Cochrane, Google Scholar, Web of Science, Embase, and Scopus databases for comparative studies with control groups that described the use of ERAS in all types of pediatric cardiac surgeries from 2000 to 2024. The data collected included study design, patient demographics, elements of the ERAS protocols, and postoperative outcomes. The random-effects model was used to calculate the pooled odds ratios (ORs) and mean differences (MDs) with the corresponding confidence intervals (CIs) for proportional and continuous variables, respectively.</p><p><strong>Results: </strong>Five studies, involving 1,008 patients, were included in the final analysis: three randomized controlled trials (RCTs), one retrospective cohort, and one case-control study. The ERAS protocols were applied in 430 (43%) patients, and standard perioperative care was applied in 578 (57%) patients. The analysis revealed that implementing the ERAS protocol significantly reduced ICU length of stay ( <i>I</i> ²  = 98.26%; MD = -1.441; 95% CI: -2.610 to -0.273; <i>p</i>  = 0.016). The ERAS group had a comparable rate of postoperative complications to the standard care group ( <i>I</i> ²  = 15.3%; OR: 0.889; 95% CI: 0.622-1.269; <i>p</i>  = 0.516).</p><p><strong>Conclusions: </strong>The ERAS protocols in pediatric cardiac surgery appear to be safe and effective in improving certain short-term outcomes. However, evidence is limited due to the small number of studies. Further multicenter RCTs that fully incorporate the ERAS protocol elements and assess both immediate and long-term outcomes are needed.</p>","PeriodicalId":32889,"journal":{"name":"Avicenna Journal of Medicine","volume":"15 2","pages":"80-85"},"PeriodicalIF":0.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Diagnosis of Sepsis-Associated Encephalopathy Using Biomarkers: Are We There Yet?","authors":"Florin Scarlatescu, Ecaterina Scarlatescu, Dana R Tomescu, Daniela Bartos","doi":"10.1055/s-0045-1808060","DOIUrl":"10.1055/s-0045-1808060","url":null,"abstract":"<p><p>Sepsis-associated encephalopathy (SAE) is a diffuse brain dysfunction that occurs in patients with sepsis in the absence of direct central nervous system infection or other causes of encephalopathy. SAE is common, occurring in up to 70% of patients with sepsis, and is linked to various clinical manifestations and significantly poorer outcomes. The diagnosis of SAE usually relies on clinical examination, which is often difficult due to confounding factors in critically ill patients. Other diagnostic tools used include electroencephalography, neuroimaging, and biomarkers. We performed a systematic search and review to synthesize all available evidence on biomarkers used for SAE diagnosis in clinical practice and highlight future directions for research. The literature search in MEDLINE identified 18 eligible studies. Biomarkers reflecting inflammation, endothelial activation and damage, astrocytic and microglial activation, neuronal injury, and metabolism changes were described, demonstrating their usefulness and potential in diagnosing and evaluating SAE. However, among different studies, the reported sensitivity and specificity of the biomarkers for diagnosing SAE varied based on the populations studied and the cutoff levels considered for each biomarker. In conclusion, biomarkers may be useful for diagnosing and predicting outcomes in SAE, but their usefulness in clinical practice remains limited for the moment. More research is needed to identify biomarkers that can improve SAE diagnosis.</p>","PeriodicalId":32889,"journal":{"name":"Avicenna Journal of Medicine","volume":"15 2","pages":"51-63"},"PeriodicalIF":0.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Methodological Quality of Case Series Published Early vs. Late in the Course of a Pandemic: A Meta-Epidemiologic Study.","authors":"Yahya Alsawaf, Mohammed Firwana, Tarek Nayfeh, Mohamed O Seisa, Reem A Alsibai, Alzhraa S Abbas, Elizabeth H Lees, Ye Zhu, Michael E Wolf, Greg Vanichkachorn, Moustafa Hegazi, Larry J Prokop, M Hassan Murad, Samer Saadi","doi":"10.1055/s-0045-1806762","DOIUrl":"10.1055/s-0045-1806762","url":null,"abstract":"<p><p><b>Introduction</b>  Case reports and series are critical to guide initial decision-making in a pandemic, but may have lower rigor because of the need to publish them quickly. This meta-epidemiologic study compares the methodological quality of case series that described the acute coronavirus disease 2019 (COVID-19) pandemic in 2020 versus those that described long-haul cases. <b>Methods</b>  We conducted a systematic review in multiple databases for long-haul case series and reports. We identified early cases of acute COVID-19 synthesized in published systematic reviews. We evaluated the methodological quality by pairs of independent reviewers using a tool dedicated for appraising case series. <b>Results</b>  We included 239 original case series (81 published in the first year of the pandemic and 158 published later describing long-haul COVID). The methodological quality of both groups of case series was very good (80-100% of series satisfying quality items) except for two items, the selection approach of cases included in the series and ruling out other causes that can explain the main finding described in the series. The appraisal tool demonstrated high agreement and reliability between reviewers. <b>Conclusion</b>  The methodological quality of modern case series is high, except for two quality items that represent an area for potential for improvement for authors of case series describing future pandemics.</p>","PeriodicalId":32889,"journal":{"name":"Avicenna Journal of Medicine","volume":"15 1","pages":"29-33"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12088789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Varicella Pneumonia with Deep Venous Thrombosis and Pulmonary Embolism as Rare Presentations for Male: Case Report.","authors":"Mohammad Dallah, Ahmad Hmaideh, Yaser Hashoom, Ammaar Kaesom, Nusima Gazhal","doi":"10.1055/s-0045-1802594","DOIUrl":"10.1055/s-0045-1802594","url":null,"abstract":"<p><p>This case report presents the case of a middle-aged man who experienced a rare and severe presentation of varicella infection, with the development of varicella pneumonia and the rare complications of deep venous thrombosis, and a subsequent pulmonary embolism. Despite being immunocompetent, the patient's varicella infection resulted in an atypical and complex clinical course. The individual initially presented with a vesicopustular rash, fever, and fatigue, which progressed to severe hypoxia and dyspnea. Radiological findings revealed diffuse bilateral nodular consolidation consistent with varicella pneumonia. Although varicella pneumonia is well documented, its occurrence in immunocompetent individuals is uncommon. In the context of varicella infection, it is very rare, particularly in the absence of immunodeficiency and with no other risk factors, in a male patient. This case underscores the importance of maintaining a high index of clinical suspicion to promptly diagnose and treat potentially life-threatening complications associated with varicella infection in otherwise healthy individuals. Key learning points include the necessity of early recognition and intervention to mitigate severe complications and the potential need for thromboprophylaxis in varicella pneumonia patients and suggests the potential need for thromboprophylaxis in patients with varicella pneumonia to prevent thrombotic events.</p>","PeriodicalId":32889,"journal":{"name":"Avicenna Journal of Medicine","volume":"15 1","pages":"46-49"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12088795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Pediatric Neuroblastoma: A Comprehensive Analysis of Adrenal and Nonadrenal Tumor Characteristics in the United States.","authors":"Ghaith AlWawi, Mohammad Omar Alrefai, Mohd Zaki Al-Wawi, Asma Qasim, M Bakri Hammami","doi":"10.1055/s-0045-1807243","DOIUrl":"10.1055/s-0045-1807243","url":null,"abstract":"<p><strong>Background and purpose: </strong>Neuroblastoma (NB) is an aggressive malignant tumor arising from a primitive neural crest origin. While the significance of tumor location in survival outcomes is recognized, it remains inadequately explored. This study provides a comprehensive analysis of the survival and characteristics of pediatric adrenal and nonadrenal NBs in the United States.</p><p><strong>Methods: </strong>A retrospective analysis of pediatric primary NB between 1975 and 2016 was conducted using the Surveillance, Epidemiology, and End Results (SEER) database. Univariate and multivariate regression analyses were used to determine prognostic variables.</p><p><strong>Results: </strong>A total of 4,554 patients were included, comprising 52% males ( <i>n</i>  = 2,385) and 79.2% Caucasians ( <i>n</i>  = 3,569). The median age of the patients was one year (range: 0-19 years). In all, 44.4% ( <i>n</i>  = 1,996) of the patients had adrenal NB and 55.6% ( <i>n</i>  = 2,496) patients had nonadrenal NB. Adrenal NB was significantly more prevalent among males and those presenting at a younger age ( <i>p</i>  < 0.001). Adrenal NB was more likely to have a higher grade and distant metastasis at diagnosis ( <i>p</i>  < 0.001). Nonadrenal NB, female sex, surgical resection, and later year of diagnosis were associated with improved survival ( <i>p</i>  < 0.001).</p><p><strong>Conclusion: </strong>This study highlights important factors that are helpful for prognostication of NB patients in the United States. Tailored approaches considering tumor site are crucial for effective management of NB.</p>","PeriodicalId":32889,"journal":{"name":"Avicenna Journal of Medicine","volume":"15 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12088804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CD11b Expression Level Measurement to Distinguish Asthma Phenotype in Pediatric Patients.","authors":"Tien Budi Febriani, Soeroyo Mahfudz, Emi Azmi Choironi, Ninda Devita, Adika Zhulhi Arjana, Muhammad Nur Imansyah","doi":"10.1055/s-0045-1802666","DOIUrl":"10.1055/s-0045-1802666","url":null,"abstract":"<p><p><b>Background</b>  Inflammation is involved in asthma pathogenesis. Based on the majority of inflammatory cells found in blood samples, asthma is divided into neutrophilic and eosinophilic phenotype. CD11b is a leukocyte surface antigen that is involved in the inflammation process. However, the immunologic response mechanism in asthma phenotypes, especially in pediatric population, is still unclear. The aim of this study was to find the difference of CD11b expression in neutrophilic and eosinophilic phenotype of asthma in pediatric patients. <b>Methods</b>  This is an analytic nonexperimental study. Data are gathered with cross-sectional method. Study subject is pediatric patients (5-17 years old) with asthma in Persaudaraaan Djamaah Hadji Indonesia and Wonosari hospitals. Blood samples for leukocyte differential count were obtained from patients who met the inclusion and exclusion criteria. Samples were analyzed with flow cytometry to measure the CD11b level. The obtained data was analyzed with independent <i>t</i> -test with Medcalc software. <b>Result</b>  A total of 40 patients were enrolled in this study. Based on blood sample analysis, 70% patients had neutrophilic asthma and 30% patients had eosinophilic asthma. There was no significant difference between patient ages mean in both groups (7.071 vs. 7.471; <i>p</i>  = 0.7186). The mean of leukocyte count was significantly higher in patients with neutrophilic asthma, compared with eosinophilic asthma (8.468 vs. 4.817 × 10 ⁹ /L; <i>p</i>  = 0.0008). CD11b expression in neutrophilic asthma was significantly higher than eosinophilic asthma ( <i>p</i>  = 0.046). No association was found between CD11b expression levels with age, sex, and body mass index. <b>Conclusion</b>  CD11b expression level is higher in neutrophilic phenotype compared with the eosinophilic phenotype in pediatric asthma patients. Its increased expression could provide insights into the mechanisms driving airway inflammation and remodeling. This marker might be explored as a target for novel therapies aimed at modulating immune activation to reduce asthma exacerbations and improve long-term outcomes.</p>","PeriodicalId":32889,"journal":{"name":"Avicenna Journal of Medicine","volume":"15 1","pages":"17-23"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12088790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Research Articles Published in Medical Journals be Used as Expert Evidence in Medical Negligence Cases?-A Cross-Sectional Retrospective Study of Indian Court Judgments.","authors":"Aakash Sethi, Kalpita Shringarpure","doi":"10.1055/s-0045-1806761","DOIUrl":"10.1055/s-0045-1806761","url":null,"abstract":"<p><p><b>Background</b>  The patient party is responsible for producing expert evidence to prove the negligence of a doctor, which becomes difficult due to lack of doctor's willingness to testify against other doctors. Impact factor (IF) is a surrogate to compare the quality of medical journals, which can be divided into low IF (< 10) and high IF (> 10). We aim to analyze various medical negligence cases where the medical journal was cited in court judgments on the parameters like court's verdict, IF of journals cited, compensation awarded, etc. <b>Methods</b>  This is a cross-sectional descriptive analysis. Judgments were accessed from www.scconline.com . IF was accessed from Clarivate Analytics 2019 ratings. Judgments having the word \"Medical\" AND \"Negligence\" in which either patient or doctor cited any journal data as evidence were included. The ci-square test was used as test of significance. <b>Results</b>  Twenty-six judgments met the inclusion criteria, with seven verdicts in favor of doctor (27%). The median IF was 2.455 with the <i>New England Journal of Medicine</i> having the highest IF (70.67). The median compensation awarded was 7.5 lakhs. The verdict of the court (doctor's win or loss) was not dependent on the IF (low IF or High IF) of the journal (chi-square = 0.16, <i>p</i>  = 0.68). <b>Conclusion</b>  All types of courts handling medical negligence, viz., criminal court, consumer/civil court, writ court, and medical councils, accept medical journal research papers even as the sole evidence in the case of medical negligence. Most of the journals cited were low IF journals.</p>","PeriodicalId":32889,"journal":{"name":"Avicenna Journal of Medicine","volume":"15 1","pages":"34-40"},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12088802/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}