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Development of bio-graphite from waste coffee grounds via catalytic graphitization for sustainable Lithium ion batteries anodes 催化石墨化法从咖啡渣中提取生物石墨制备可持续锂离子电池负极
IF 5.9 3区 材料科学
FlatChem Pub Date : 2025-04-11 DOI: 10.1016/j.flatc.2025.100867
JeongA Kim, Donghyeon Yu, Daeup Kim, Jungpil Kim, Junghoon Yang
{"title":"Development of bio-graphite from waste coffee grounds via catalytic graphitization for sustainable Lithium ion batteries anodes","authors":"JeongA Kim,&nbsp;Donghyeon Yu,&nbsp;Daeup Kim,&nbsp;Jungpil Kim,&nbsp;Junghoon Yang","doi":"10.1016/j.flatc.2025.100867","DOIUrl":"10.1016/j.flatc.2025.100867","url":null,"abstract":"<div><div>This study presents a sustainable approach to synthesizing carbon-based anode materials for lithium-ion batteries (LIBs) using waste coffee grounds. Two types of carbon were prepared: disordered hard carbon (C-HC) via direct carbonization, and highly crystalline graphite-like carbon (C-AG) through iron-catalyzed graphitization at 1500 °C. Structural analysis using X-ray diffraction (XRD) and Raman spectroscopy confirmed the successful transformation from disordered to graphitic carbon. The interlayer spacing decreased from 3.52 Å (C-HC) to 3.36 Å (C-AG), and the I<sub>D</sub>/I<sub>G</sub> ratio dropped from 1.20 to 0.05, indicating enhanced crystallinity and reduced defect density. C-AG exhibited a high reversible capacity of 286 mAh g<sup>−1</sup> and an initial Coulombic efficiency of 85.5 %, attributed to lithium intercalation through the staging mechanism in well-aligned graphene layers. In contrast, C-HC showed a lower capacity of 156 mAh g<sup>−1</sup> and an efficiency of 73.9 %, with lithium mainly stored at surface defects and disordered regions. Despite its lower capacity, C-HC demonstrated superior rate performance, retaining 58.0 % of its capacity at 1000 mA g<sup>−1</sup>, compared to 18.6 % for C-AG. These results reveal a trade-off between structural crystallinity and rate capability, providing insights into the structure-property relationship in biomass-derived carbon anodes. This work demonstrates the feasibility of catalytic graphitization as a pathway to convert biowaste into high-performance graphite materials for energy storage applications.</div></div>","PeriodicalId":316,"journal":{"name":"FlatChem","volume":"51 ","pages":"Article 100867"},"PeriodicalIF":5.9,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143848080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From graphene to MXenes: Harnessing the power of 2D materials for enhanced sodium-ion battery performance 从石墨烯到MXenes:利用二维材料的力量增强钠离子电池的性能
IF 5.9 3区 材料科学
FlatChem Pub Date : 2025-04-11 DOI: 10.1016/j.flatc.2025.100866
Manjot Kaur , Piyush Sharma , Rameez Mir , Kamalpreet Kaur , Ram K. Sharma , Akshay Kumar
{"title":"From graphene to MXenes: Harnessing the power of 2D materials for enhanced sodium-ion battery performance","authors":"Manjot Kaur ,&nbsp;Piyush Sharma ,&nbsp;Rameez Mir ,&nbsp;Kamalpreet Kaur ,&nbsp;Ram K. Sharma ,&nbsp;Akshay Kumar","doi":"10.1016/j.flatc.2025.100866","DOIUrl":"10.1016/j.flatc.2025.100866","url":null,"abstract":"<div><div>In the quest for sustainable energy storage solutions, sodium-ion batteries (SIBs) have emerged as promising alternatives to lithium-ion batteries due to the abundance and low cost of sodium resources. Among the key factors influencing the performance of SIBs, the choice of electrode materials stands out as a critical determinant. Two-dimensional (2D) materials have garnered significant attention in this regard owing to their unique properties and tunable characteristics. This comprehensive review delves into recent advancements in the application of various 2D materials for sodium-ion battery technologies. Specifically, we explore the utilization of graphene, phosphorene, transition metal dichalcogenides (TMDs), metal-organic frameworks (MOFs), and MXenes as electrode materials in SIBs. Through an in-depth analysis of the synthesis methods, structural properties, and electrochemical performance of these materials, this paper provides valuable insights into their potential for enhancing the energy storage capabilities of sodium-ion batteries. Furthermore, the challenges and opportunities associated with the practical implementation of 2D materials in SIBs are discussed, along with perspectives on future research directions aimed at realizing efficient and scalable sodium-ion battery technologies.</div></div>","PeriodicalId":316,"journal":{"name":"FlatChem","volume":"51 ","pages":"Article 100866"},"PeriodicalIF":5.9,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143859254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An efficient charge-carrier separation in vanadium-based MXene ternary heterostructure with enhanced photoelectrocatalytic properties 具有增强光电催化性能的钒基MXene三元异质结构的高效载流子分离
IF 5.9 3区 材料科学
FlatChem Pub Date : 2025-04-08 DOI: 10.1016/j.flatc.2025.100865
Daniel Muvengei Mwangangi , Thollwana Andretta Makhetha , Jane Catherine Ngila , Langelihle Nsikayezwe Dlamini
{"title":"An efficient charge-carrier separation in vanadium-based MXene ternary heterostructure with enhanced photoelectrocatalytic properties","authors":"Daniel Muvengei Mwangangi ,&nbsp;Thollwana Andretta Makhetha ,&nbsp;Jane Catherine Ngila ,&nbsp;Langelihle Nsikayezwe Dlamini","doi":"10.1016/j.flatc.2025.100865","DOIUrl":"10.1016/j.flatc.2025.100865","url":null,"abstract":"<div><div>Tungsten trioxide (WO<sub>3</sub>) and zinc indium sulfide (ZnIn<sub>2</sub>S<sub>4</sub>) are among photocatalysts with excellent light absorption properties. However, single photocatalyst suffers from rapid charge carrier recombination. For improved photoelectrocatalytic properties, herein, we report fabrication of a novel S-scheme ternary heterostructure (V<sub>2</sub>CT<sub>x</sub>@WO<sub>3</sub>/ZnIn<sub>2</sub>S<sub>4</sub>). Due to the high electrical conductivity of V<sub>2</sub>CT<sub>x</sub> MXene, its presence in the heterostructure offers efficient charge transfer kinetics at the interface. Monoclinic WO<sub>3</sub> and cubic ZnIn<sub>2</sub>S<sub>4</sub> were confirmed by X-ray diffraction spectroscopy including crystallite size and micro-strain. Ternary composites demonstrated red shift in light absorption wavelength, with band gap energies as low as 1.58 eV compared to 2.21 for ZnIn<sub>2</sub>S<sub>4</sub> and 2.55 eV for WO<sub>3</sub>. Photoluminescence and electron impedance spectroscopy demonstrated effective charge separation with low charge transfer resistance by the ternary composite (5 % VWZ). Work functions for ZnIn<sub>2</sub>S<sub>4</sub> (6.68 eV), WO<sub>3</sub> (7.08 eV), and V<sub>2</sub>CT<sub>x</sub> (8.70 eV) confirmed the creation of an internal electric field at the interface of the semiconductors. Electron migration occurred from ZnIn<sub>2</sub>S<sub>4</sub> to WO<sub>3</sub> due to changes in binding energies as indicated by XPS data confirming S-scheme heterostructure.</div></div>","PeriodicalId":316,"journal":{"name":"FlatChem","volume":"51 ","pages":"Article 100865"},"PeriodicalIF":5.9,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143808247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanistic insights into diffusion-controlled 2D WSe2 growth via chemical vapor deposition in confined spaces 通过化学气相沉积在密闭空间中扩散控制二维WSe2生长的机理
IF 5.9 3区 材料科学
FlatChem Pub Date : 2025-04-03 DOI: 10.1016/j.flatc.2025.100863
Yebin Lee , Naechul Shin
{"title":"Mechanistic insights into diffusion-controlled 2D WSe2 growth via chemical vapor deposition in confined spaces","authors":"Yebin Lee ,&nbsp;Naechul Shin","doi":"10.1016/j.flatc.2025.100863","DOIUrl":"10.1016/j.flatc.2025.100863","url":null,"abstract":"<div><div>Two-dimensional transition metal dichalcogenides (TMDs) have garnered significant attention for their potential in electronic and optoelectronic devices. While chemical vapor deposition (CVD) is a primary technique for producing large-area monolayer TMDs, the use of metal oxide precursors with high melting points presents various synthetic limitations. As an alternative, metal salt-based precursors have emerged due to their water solubility and low melting points. However, challenges remain in obtaining high-quality TMDs from these liquid precursors to, largely due to a limited understanding of the precursor diffusion process. Here, we present a systematic study on spin-coated precursor-based CVD growth of WSe<sub>2</sub> in confined spaces, demonstrating a significant enhancement in the uniformity of domain size and number density through regulated precursor diffusion achieved by substrate covering. Furthermore, we show that microscopic precursor diffusion, both within and beyond the flake edges, influences edge morphologies and local optical emission properties. These findings provide valuable insights into the fabrication of large-area TMD monolayers, which hold promise for electronic and optoelectronic applications.</div></div>","PeriodicalId":316,"journal":{"name":"FlatChem","volume":"51 ","pages":"Article 100863"},"PeriodicalIF":5.9,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular caffeine electrode for hydrogen production using two or three electrode configurations in sulphuric acid electrolyte solution on a graphite's surface 在石墨表面的硫酸电解质溶液中使用两个或三个电极配置的分子咖啡因电极用于制氢
IF 5.9 3区 材料科学
FlatChem Pub Date : 2025-04-03 DOI: 10.1016/j.flatc.2025.100864
Dieketseng Tsotetsi , Tumelo Seadira , Olayemi J. Fakayode , Mayetu Segale , Bakang Mothudi , Pontsho Mbule , Mokhotjwa Dhlamini
{"title":"Molecular caffeine electrode for hydrogen production using two or three electrode configurations in sulphuric acid electrolyte solution on a graphite's surface","authors":"Dieketseng Tsotetsi ,&nbsp;Tumelo Seadira ,&nbsp;Olayemi J. Fakayode ,&nbsp;Mayetu Segale ,&nbsp;Bakang Mothudi ,&nbsp;Pontsho Mbule ,&nbsp;Mokhotjwa Dhlamini","doi":"10.1016/j.flatc.2025.100864","DOIUrl":"10.1016/j.flatc.2025.100864","url":null,"abstract":"<div><div>The surface modification of graphite electrodes for hydrogen production using caffeine was investigated in sulphuric acid electrolyte. Characterization of both the graphite and the modified graphite with caffeine was conducted using FTIR, TGA, and SEM techniques. Additionally, an evaluation of hydrogen production was carried out using a direct current power supply set at various voltages (2, 4, 6, 8, and 10 <em>V</em>) and with an Autolab Workstation for cyclic voltammetry (CV), linear scan voltammetry (LSV) and chronoamperometric analyses. A hydrogen evolution current of density of −1000 mA/cm<sup>2</sup> corresponding to −0.65 <em>V</em> (vs RHE) and 6.36 mA/cm<sup>2</sup> corresponding to 9.803 V (vs RHE) were achieved under two-electrode chronoamperometric evaluations and direct current power supply set-up, respectively.</div></div>","PeriodicalId":316,"journal":{"name":"FlatChem","volume":"51 ","pages":"Article 100864"},"PeriodicalIF":5.9,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143767769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study on the dielectric properties of fluorinated graphene 氟化石墨烯介电性能研究
IF 5.9 3区 材料科学
FlatChem Pub Date : 2025-03-28 DOI: 10.1016/j.flatc.2025.100862
Zixuan Gou , Weibin Xi , Wei Jiang , Zekai Zhang , Jinping Zhao , Jin Zhou , Yang Su
{"title":"Study on the dielectric properties of fluorinated graphene","authors":"Zixuan Gou ,&nbsp;Weibin Xi ,&nbsp;Wei Jiang ,&nbsp;Zekai Zhang ,&nbsp;Jinping Zhao ,&nbsp;Jin Zhou ,&nbsp;Yang Su","doi":"10.1016/j.flatc.2025.100862","DOIUrl":"10.1016/j.flatc.2025.100862","url":null,"abstract":"<div><div>The rapid evolution of fifth-generation (5G) communication technology calls for next-generation packaging materials that not only excel in dielectric performance like dielectric constant and dielectric loss but push the demand for thermal stability. Here, we explore superhydrophobic fluorinated graphene (FG), revealing a remarkable combination of dielectric properties and thermal stability that make FG a standout candidate for electronic packaging in 5G applications. By fine-tuning the fluorine-to‑carbon (F/C) ratio in the FG, we have achieved a dielectric constant as low as 1.50 with an F/C ratio of 1.18, significantly lower than many conventional materials. Even more impressively, our FG exhibits an ultra-low dielectric loss of just 0.0037 at 10 MHz. Beyond its outstanding electrical performance, FG boasts exceptional thermal stability, with a decomposition temperature high to ∼500 °C, far surpassing standard polymers for packaging materials. Moreover, its hydrophobic nature remains stable in outdoor environments, cementing its reliability over time. With its low dielectric constant, minimal dielectric loss, high thermal resilience, and environmental durability, FG holds tremendous promise as a competitive candidate in advanced packaging materials for 5G technology.</div></div>","PeriodicalId":316,"journal":{"name":"FlatChem","volume":"51 ","pages":"Article 100862"},"PeriodicalIF":5.9,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143739894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of sensitive Mn@TiO2/RGO nanocomposite-based sensor for the detection of sunset yellow in food samples 基于Mn@TiO2/RGO纳米复合材料的食品中日落黄敏感传感器的研制
IF 5.9 3区 材料科学
FlatChem Pub Date : 2025-03-18 DOI: 10.1016/j.flatc.2025.100861
Venkatachalam Vinothkumar , Yellatur Chandra Sekhar , Shen-Ming Chen , Tae Hyun Kim
{"title":"Development of sensitive Mn@TiO2/RGO nanocomposite-based sensor for the detection of sunset yellow in food samples","authors":"Venkatachalam Vinothkumar ,&nbsp;Yellatur Chandra Sekhar ,&nbsp;Shen-Ming Chen ,&nbsp;Tae Hyun Kim","doi":"10.1016/j.flatc.2025.100861","DOIUrl":"10.1016/j.flatc.2025.100861","url":null,"abstract":"<div><div>Sunset yellow (SSY) is a synthetic azo dye that is widely employed in the food industries to improve the appearance, color, and texture of products. However, excessive usage of SSY could lead to toxicity and pathogenicity to human health and food safety. Hence, a reliable and sensitive electrochemical sensor for SSY detection in food samples is essential. In this study, we utilized a simple and cost-effective sonochemical methodology to fabricate Mn@TiO<sub>2</sub>/RGO nanocomposite for the sensitive electrochemical detection of SSY. The crystallinity, composition, and morphology of the as-prepared Mn@TiO<sub>2</sub>/RGO nanocomposite were analyzed using various systematic analytical techniques. The integration of Mn@TiO<sub>2</sub> and RGO nanoarchitecture demonstrated a high specific surface area, better conductivity, and outstanding synergistic effect that significantly enhanced the current response and electron transfer rate of the electrode material. The modified glassy carbon electrode with Mn@TiO<sub>2</sub>/RGO/GCE achieved a dynamic linear range of 0.02–535.62 μM and a low limit of detection (LOD) of 0.028 μM in the determination of SSY using differential pulse voltammetry (DPV). Furthermore, the Mn@TiO<sub>2</sub>/RGO/GCE sensor demonstrated excellent selectivity, stability, repeatability, and reproducibility in detecting SSY. The practicality of the fabricated sensor was also proved by successfully detecting trace levels of SSY in candy and mixed fruit juice samples with acceptable recoveries. This work introduces a low-cost and synergistic approach of cost-effective Mn@TiO<sub>2</sub> combined with RGO for analyzing food colorants in commercial products.</div></div>","PeriodicalId":316,"journal":{"name":"FlatChem","volume":"51 ","pages":"Article 100861"},"PeriodicalIF":5.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dual fluorescent and time-dependent two-dimensional molecular crystals (DFTD-2DMC) as the effective fluorescent probes for sensing trace water in THF 双荧光和时变二维分子晶体(DFTD-2DMC)作为检测四氢呋喃中痕量水的有效荧光探针
IF 5.9 3区 材料科学
FlatChem Pub Date : 2025-03-17 DOI: 10.1016/j.flatc.2025.100860
Deepak Dabur , Nallin Sharma , Priyanka Rana , Hui-Fen Wu
{"title":"Dual fluorescent and time-dependent two-dimensional molecular crystals (DFTD-2DMC) as the effective fluorescent probes for sensing trace water in THF","authors":"Deepak Dabur ,&nbsp;Nallin Sharma ,&nbsp;Priyanka Rana ,&nbsp;Hui-Fen Wu","doi":"10.1016/j.flatc.2025.100860","DOIUrl":"10.1016/j.flatc.2025.100860","url":null,"abstract":"<div><div>For the first time, we have synthesized the dual fluorescent and time-dependent 2-dimensional molecular crystals (DFTD-2DMCs) which is a novel type of pure organic molecule nanosheets that exhibit the features of distinctive optical characteristics (dual fluorescence) with the various structural confirmations while exploring the interaction of pentacene-quinone derivative (2P-1) with tetrahydrofuran (THF). A number of solvents with different polarities were investigated in order to check the feasibility to produce the DFTD-2DMCs. These DFTD-2DMCs are further employed as luminous water sensors with high sensitivity and varied luminescence centers due to their distinctive optical and structural features. The donor-accepter-donor type complexes 2DMC-1 and 2 with electron-rich phenyl groups display an intermolecular charge transfer (ICT) state and form aggregates when detecting trace water in THF. The luminescence is reduced after contact with water, allowing quantitative analysis to quantify the water amount. The DFTD-2DMCs' capacity as a highly sensitive water sensor in an organic solvent (THF) was first demonstrated in this study by the lowest LODs for THF with 2DMC-1 (0.05 %) and 2DMC-2 (0.01 %). This novel observation is a pioneering approach for opening a new type of sensor by using the DFTD-2DMC.</div></div>","PeriodicalId":316,"journal":{"name":"FlatChem","volume":"51 ","pages":"Article 100860"},"PeriodicalIF":5.9,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New strategy for non-enzymatic determination of lactate via regeneration of cofactor NADH using flexible electrochemical sensors prepared with nitrogen-doped graphene oxide conductive ink 利用氮掺杂氧化石墨烯导电油墨制备的柔性电化学传感器,通过辅助因子NADH再生非酶测定乳酸的新策略
IF 5.9 3区 材料科学
FlatChem Pub Date : 2025-03-12 DOI: 10.1016/j.flatc.2025.100848
Ebrar Dokur, Ozge Gorduk, Yucel Sahin
{"title":"New strategy for non-enzymatic determination of lactate via regeneration of cofactor NADH using flexible electrochemical sensors prepared with nitrogen-doped graphene oxide conductive ink","authors":"Ebrar Dokur,&nbsp;Ozge Gorduk,&nbsp;Yucel Sahin","doi":"10.1016/j.flatc.2025.100848","DOIUrl":"10.1016/j.flatc.2025.100848","url":null,"abstract":"<div><div>This study presents a novel approach for non-enzymatic lactate detection by regenerating NADH using NAD<sup>+</sup> instead of traditional enzymes or metal nanoparticles. The electrodes were fabricated from the developed conductive inks, demonstrating a clear correlation between the lactate concentration and NADH oxidation peak current. In this system, lactate functions not only as an analyte but also as a proton source, enhancing the regeneration of NADH during the electrochemical reduction of NAD<sup>+</sup>. The incorporation of nitrogen-doped graphene oxide into the conductive ink as a second proton source further improved NADH formation, increasing the overall efficiency of lactate detection. The electrodes were thoroughly characterized using cyclic voltammetry, electrochemical impedance spectroscopy, field-emission scanning electron microscopy, energy dispersive X-ray spectrometry, Fourier transform infrared spectroscopy, and X-ray photoelectron spectroscopy. The electrodes achieved detection limit of 2.11 μM for lactate. Importantly, the developed electrodes successfully detected lactate in artificial sweat samples, thereby highlighting their practical applicability. This research not only advances the field of electrochemical biosensing, but also opens new avenues for monitoring lactate levels in biological and clinical settings, showcasing the potential of enzyme-free detection methods.</div></div>","PeriodicalId":316,"journal":{"name":"FlatChem","volume":"51 ","pages":"Article 100848"},"PeriodicalIF":5.9,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143621137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MXenes in combination therapy: Chemo-photothermal, chemodynamic, and photothermal/photodynamic therapies for cancer treatment and antibacterial applications MXenes在联合治疗中的应用:化学光热,化学动力,光热/光动力治疗癌症和抗菌应用
IF 5.9 3区 材料科学
FlatChem Pub Date : 2025-03-11 DOI: 10.1016/j.flatc.2025.100849
Masoomeh Amoozadeh , Atefeh Zarepour , Arezoo Khosravi , Siavash Iravani , Ali Zarrabi
{"title":"MXenes in combination therapy: Chemo-photothermal, chemodynamic, and photothermal/photodynamic therapies for cancer treatment and antibacterial applications","authors":"Masoomeh Amoozadeh ,&nbsp;Atefeh Zarepour ,&nbsp;Arezoo Khosravi ,&nbsp;Siavash Iravani ,&nbsp;Ali Zarrabi","doi":"10.1016/j.flatc.2025.100849","DOIUrl":"10.1016/j.flatc.2025.100849","url":null,"abstract":"<div><div>Two-dimensional MXenes and their derivatives have attracted significant attention in recent years for their potential applications in combination therapies, specifically in chemo-photothermal, chemodynamic, and photothermal/photodynamic treatments. MXenes offer distinct advantages in combination therapies due to their exceptional electrical conductivity, hydrophilicity, large surface area, tunable surface chemistry, and ability to enhance drug delivery and therapeutic efficacy through multifunctional applications. By incorporating MXenes into combination therapies, researchers have demonstrated enhanced therapeutic efficacy through synergistic mechanisms that improve drug delivery, increase localized heating, and amplify the generation of reactive oxygen species, thereby effectively targeting and eliminating cancer cells or contaminations. However, stability in biological environments remains a primary concern, as degradation can compromise their therapeutic effectiveness and safety. Ensuring biocompatibility is crucial, since the introduction of MXenes and their composites may trigger immune responses or cytotoxicity. Moreover, optimizing the synthesis of high-quality MXenes with uniform properties remains a logistical challenge, affecting reproducibility and scalability for clinical applications. By consolidating existing knowledge and identifying future directions, this review aims to advance MXene-based combination chemo-photothermal, chemodynamic, and photothermal/photodynamic therapies for cancer treatment and antibacterial applications, ultimately paving the way for innovative strategies in biomedicine and personalized medicine.</div></div>","PeriodicalId":316,"journal":{"name":"FlatChem","volume":"51 ","pages":"Article 100849"},"PeriodicalIF":5.9,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143628346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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