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Influential Factors on Postgraduates' Satisfaction with the Quality of Pharmacy Education: Evidence from a University in Vietnam. 研究生对药学教育质量满意度的影响因素:来自越南某大学的证据。
IF 2
Pharmacy Pub Date : 2025-04-29 DOI: 10.3390/pharmacy13030062
Do Xuan Thang, Nguyen Viet Hung, Vu Tran Anh, Vu Thi Quynh Mai, Le Thu Thuy, Cuc Thi Thu Nguyen, Trung Nguyen Duc, Dang Viet Hung
{"title":"Influential Factors on Postgraduates' Satisfaction with the Quality of Pharmacy Education: Evidence from a University in Vietnam.","authors":"Do Xuan Thang, Nguyen Viet Hung, Vu Tran Anh, Vu Thi Quynh Mai, Le Thu Thuy, Cuc Thi Thu Nguyen, Trung Nguyen Duc, Dang Viet Hung","doi":"10.3390/pharmacy13030062","DOIUrl":"10.3390/pharmacy13030062","url":null,"abstract":"<p><p>The study aimed to investigate the determinants of pharmacy postgraduates' satisfaction to suggest essential recommendations to enhance educational quality at Hanoi University of Pharmacy in Vietnam. A cross-sectional survey was conducted among 202 postgraduates using structured questionnaires, with 31 multidimensional questions and 1 question addressing overall satisfaction. Cronbach's alpha was used to evaluate the questionnaire's internal consistency, Exploratory Factor Analysis (EFA) identified key factors, and multiple linear regression analysis was applied to assess the impact of these factors. Overall satisfaction had a high mean score of 4.49 out of 5 (SD = 0.602). The final 29 questions were retained and divided into four main factors affecting satisfaction after rotating EFA. The dimension of \"Support and Evaluation\" was the most influential factor (β = 0.475), followed by \"Training Organization\", \"Facilities and Library\", and \"Lecturers and Curriculum\". The variables with the lowest scores needed much more attention, including digital systems (4.2, SD = 0.852), information technology support (4.32, SD = 0.772), activities boosting lifelong learning skills (4.48, SD = 0.624), and the reasonability of the education program's structure (4.48, SD = 0.608) and the studying program's schedule (4.45, SD = 0.607). The findings indicate the issues that should be addressed, and have highlighted that improvements in electronic library accessibility and updated curricula are also recommended to further optimize the educational experience of postgraduate students.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"13 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heat Therapy for Musculoskeletal Pain Conditions: Actionable Suggestions for Pharmacists from a Panel of Experts. 肌肉骨骼疼痛条件的热疗法:专家小组对药剂师的可操作建议。
IF 2
Pharmacy Pub Date : 2025-04-29 DOI: 10.3390/pharmacy13030063
Flavia Nossa, Massimiliano Franco, Alberto Magni, Emanuela Raimondo, Giuseppe Ventriglia, Fabrizio Gervasoni
{"title":"Heat Therapy for Musculoskeletal Pain Conditions: Actionable Suggestions for Pharmacists from a Panel of Experts.","authors":"Flavia Nossa, Massimiliano Franco, Alberto Magni, Emanuela Raimondo, Giuseppe Ventriglia, Fabrizio Gervasoni","doi":"10.3390/pharmacy13030063","DOIUrl":"10.3390/pharmacy13030063","url":null,"abstract":"<p><p>Musculoskeletal disorders represent one of the most pervasive health concerns that drive frequent medical consultations and pharmacy encounters. Community pharmacies are well placed to help address this demand as they are accessible settings for healthcare advice and support for patients with musculoskeletal disorders complaining of pain. Heat therapy stands as a valuable component of a multimodal approach to the management of musculoskeletal pain by virtue of multiple effects: pain relief, reduction of muscle spasms and stiffness, and enhanced muscle flexibility and range of motion. However, there is limited guidance on heat therapy use in routine practice, particularly on indications and contraindications, mode of application, and precautions. Such an educational gap has been documented among pharmacists. Therefore, it is paramount that pharmacists gain knowledge about when and how to effectively integrate superficial heat therapy with both pharmacological and physical therapy, to provide patients with a comprehensive, multimodal approach to alleviating musculoskeletal pain. A multidisciplinary panel of experts gathered to develop practical guidance on heat therapy-appropriate application in patients with musculoskeletal pain. In this work, we provide actionable suggestions to build pharmacists' competency in managing musculoskeletal pain and empower them in effectively using heat therapy as a single therapeutic option or in combination with over-the-counter analgesics.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"13 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring Complementary Medicine Usage, Consumer Perceptions, and Impact of Label Warnings: A Cross-Sectional Study in Melbourne, Australia. 探索补充药物的使用,消费者的看法,以及标签警告的影响:澳大利亚墨尔本的一项横断面研究。
IF 2
Pharmacy Pub Date : 2025-04-27 DOI: 10.3390/pharmacy13030061
Kaveh Naseri, Thilini Thrimawithana, Ayman Allahham, Vivek Nooney, Barbora de Courten, Wejdan Shahin
{"title":"Exploring Complementary Medicine Usage, Consumer Perceptions, and Impact of Label Warnings: A Cross-Sectional Study in Melbourne, Australia.","authors":"Kaveh Naseri, Thilini Thrimawithana, Ayman Allahham, Vivek Nooney, Barbora de Courten, Wejdan Shahin","doi":"10.3390/pharmacy13030061","DOIUrl":"10.3390/pharmacy13030061","url":null,"abstract":"<p><p>Complementary medicines (CMs) are widely used worldwide, with usage rates ranging from 24% to 71.3%. Despite their popularity, many CMs lack robust scientific support and can potentially lead to adverse health effects. Limited research exists on CMs-related adverse events and the role of CMs' labels in conveying crucial information to consumers. This cross-sectional study investigated the usage, consumer perspectives, and influence of labels specifically on product-based CMs, including nutritional supplements, vitamins, minerals, probiotics, prebiotics, and herbal medicines. Practitioner-led therapies and mind-body practices were outside the scope of this research. Data were collected through an online questionnaire and analyzed using descriptive statistics and correlation analysis. The study enrolled 125 participants who were current CMs users. Pharmacies and supermarkets were the primary sources for CMs procurement. Participants' perceptions of CMs effectiveness and safety were positively correlated. Label warnings prompted participants to seek additional information, but consultation with healthcare professionals was infrequent. Adverse reactions were reported by 18.5% of participants, with self-management approaches being common. Label warnings play a significant role in prompting consumers to seek more information about CMs. However, the limited engagement of healthcare professionals, especially pharmacists, suggests an opportunity for improved consumer education and pharmacist involvement in CMs-related discussions. Addressing these aspects can lead to safer CMs practices and informed decision-making among consumers.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"13 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Clinical Pharmacy Service to Prevent Drug-Drug Interactions and Potentially Inappropriate Medication: A Consecutive Intervention Study in Older Intermediate Care Patients of a Regional Hospital. 预防药物相互作用和潜在不适当用药的临床药学服务:对某地区医院中老年护理患者的连续干预研究
IF 2
Pharmacy Pub Date : 2025-04-24 DOI: 10.3390/pharmacy13030060
Alexander Kilian Ullmann, Oliver Bach, Kathrin Mosch, Thilo Bertsche
{"title":"A Clinical Pharmacy Service to Prevent Drug-Drug Interactions and Potentially Inappropriate Medication: A Consecutive Intervention Study in Older Intermediate Care Patients of a Regional Hospital.","authors":"Alexander Kilian Ullmann, Oliver Bach, Kathrin Mosch, Thilo Bertsche","doi":"10.3390/pharmacy13030060","DOIUrl":"10.3390/pharmacy13030060","url":null,"abstract":"<p><p><i>Background:</i> In intermediate care, older patients with polypharmacy are vulnerable to drug-drug interactions (DDI) and potentially inappropriate medication (PIM). Aims: To perform a consecutive intervention study to evaluate DDI/PIM. <i>Methods:</i> Clinically-relevant DDI/PIM were identified using AMeLI (electronic medication list) and PRISCUS 2.0 (PIM list). Consecutive patients (standard care group) were screened for DDI/PIM after admission (t0) and again before discharge (t1). In an interim period, physicians received general education about DDI/PIM. Then, consecutive patients (independent clinical pharmacy group) were screened for DDI/PIM after admission (t2). Physicians were then provided with patient-individualized recommendations by a clinical pharmacist to prevent DDI/PIM. The patients were then screened again for DDI/PIM before discharge (t3). <i>Results:</i> In each group, 100 patients were included with data available for evaluation from 97 (standard care group, median age: 78 years [Q25/Q75: 69/84]) and 89 (clinical pharmacy group, 76 years [67/84]). In the standard care group, DDI were identified in 55 (57%) patients after admission (t0) and 54 (56%) before discharge (t1, ARR[t0/t1] = 0.01, NNT[t0/t1] = 100, n.s.). In the clinical pharmacy group, DDI were identified in 32 (36%) after admission (t2; ARR[t0/t2] = 0.21/NNT[t0/t2] = 5, <i>p</i> < 0.01) and 26 (29%) before discharge (t3; ARR[t2/t3] = 0.07/NNT[t2/t3] = 15, n.s.; ARR[t1/t3] = 0.27/NNT[t1/t3] = 4, <i>p</i> < 0.001). PIM were identified in patients at t0: 34 (35%), t1: 35 (36%, ARR[t0/t1] = -0.01/NNH[t0/t1] = 100, n.s.), t2: 25 (26%, ARR[t0/t2] = 0.09/NNT[t0/t2] = 12, n.s.), t3: 23 (24%, ARR[t2/t3] = 0.11/NNT[t2/t3] = 10, n.s.; ARR[t1/t3] = 0.12/NNT[t1/t3] = 9, n.s.). <i>Conclusions:</i> In the standard care group, after admission, many DDI/PIM were identified in older intermediate care patients. Before discharge, their number was hardly influenced at all. General education for physicians led to DDI prevention after admission. In addition, the DDI frequency decreased by providing physicians with patient-individualized recommendations.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"13 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring Doping Awareness: Medical Experts' Perspectives and Their Commitment to Doping Prevention. 探索兴奋剂意识:医学专家的观点和他们对兴奋剂预防的承诺。
IF 2
Pharmacy Pub Date : 2025-04-24 DOI: 10.3390/pharmacy13030059
Vanya Rangelov Kozhuharov, Radiana Staynova, Kalin Ivanov, Hristo Manev, Stanislava Ivanova
{"title":"Exploring Doping Awareness: Medical Experts' Perspectives and Their Commitment to Doping Prevention.","authors":"Vanya Rangelov Kozhuharov, Radiana Staynova, Kalin Ivanov, Hristo Manev, Stanislava Ivanova","doi":"10.3390/pharmacy13030059","DOIUrl":"10.3390/pharmacy13030059","url":null,"abstract":"<p><p>Humanity has used and explored various performance-enhancing remedies since ancient times. To protect clean sport, athletes' health, and to provide fair and transparent competitions, different anti-doping policies were implemented. Nowadays, the anti-doping policies are evolving every year and are governed by the World Anti-Doping Agency. The use of doping in sports is regarded as a persistent problem across various athletic disciplines; at the same time, the topic of whether doping is preventable is highly discussed. The aim of this study was to assess the knowledge of medical specialists about doping compounds and to analyze their willingness and preparedness to participate in doping prevention programs. A cross-sectional questionnaire-based study was conducted between March 2024 and May 2024. Study participants included medical and pharmacy students, pharmacists, and medical doctors. Statistical analysis was performed using IBM SPSS Statistics version 24.0. Descriptive statistics, one-way analysis of variance (ANOVA), and independent-samples t-test were applied to analyze different variables. The results from the study suggested that healthcare professionals, particularly pharmacists, could be successfully engaged in doping prevention. Additionally, community pharmacies could also be involved in doping-prevention strategies since they are recognized as easily accessible healthcare locations. The relationship between medical specialists and professional athletes is essential for raising awareness, receiving trustworthy information, and developing decision-making capability to prevent not only the intentional but also the unintentional anti-doping rule violations.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"13 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Training the Next Generation of Pharmacist Educators (NextGenRxEd): Outcomes from a Longitudinal 4-Year Teaching and Research Program. 培养下一代药剂师教育者(NextGenRxEd):从纵向4年教学和研究计划的结果。
IF 2
Pharmacy Pub Date : 2025-04-22 DOI: 10.3390/pharmacy13030058
Candis M Morello, Mark Bounthavong, Jan D Hirsch
{"title":"Training the Next Generation of Pharmacist Educators (NextGenRxEd): Outcomes from a Longitudinal 4-Year Teaching and Research Program.","authors":"Candis M Morello, Mark Bounthavong, Jan D Hirsch","doi":"10.3390/pharmacy13030058","DOIUrl":"10.3390/pharmacy13030058","url":null,"abstract":"<p><p>To combine didactic education with clinical and research experiences that would empower student pharmacists to consider postgraduate training and a career in pharmacy education or academics, in 2009, the Next Generation of Pharmacist Educators (NextGenRxEd) program, a four-year longitudinal education program, was implemented at the University of California San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences. Directed by two pharmacist faculty, a clinician and researcher, student pharmacists were exposed to hands-on experience with clinical management, patient care, and research processes. A post-graduation survey was created and administered in Fall 2024 to evaluate outcomes for all student pharmacists who completed the program. Key performance indicators included the number of pharmacy students proceeding to postgraduate training, research practices, and pharmacist positions involving education and academics. During 2009-2024, 34 student pharmacists completed the NextGenRxEd program; 71% achieved postgraduate education (22 PGY1 residencies and two fellowships). Following quality improvement implementation, this percentage increased from 50% to 89%, for Classes 2009-2015 and 2016-2024, respectively. Overall, the PGY1 match rate was 92%, and 19 abstracts/posters and 10 manuscripts were published, respectively. The post-graduation survey response rate was 85%, with 93% of respondents reporting that they precepted PharmD students; 14% became faculty members, and 66% participated in research. The NextGenRxEd program provides a model whereby student pharmacists are equipped to obtain post-graduate education and pursue a career with a significant role in pharmacy education or academic pharmacy. This program has the potential to be implemented at other pharmacy schools/colleges to benefit faculty and student participants.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"13 3","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SMART Pharmacist-The Impact of Education on Improving Pharmacists' Participation in Monitoring the Safety of Medicine Use in Montenegro. 聪明的药剂师-教育对提高黑山药剂师参与监测药品使用安全的影响。
IF 2
Pharmacy Pub Date : 2025-04-17 DOI: 10.3390/pharmacy13020057
Snežana Mugoša, Arijana Meštrović, Veselinka Vukićević, Milanka Žugić, Michael J Rouse
{"title":"SMART Pharmacist-The Impact of Education on Improving Pharmacists' Participation in Monitoring the Safety of Medicine Use in Montenegro.","authors":"Snežana Mugoša, Arijana Meštrović, Veselinka Vukićević, Milanka Žugić, Michael J Rouse","doi":"10.3390/pharmacy13020057","DOIUrl":"https://doi.org/10.3390/pharmacy13020057","url":null,"abstract":"<p><p>Pharmaceutical care as a concept was introduced in Montenegro during the last 10 years. The Pharmaceutical Chamber of Montenegro (PCM) and the Institute for Medicines and Medical Devices (CInMED) conducted SMART Pharmacist Program educational activities for pharmacists as a project to improve their impact on monitoring drug safety. In the period from September 2023 to May 2024, a total of 78 pharmacists participated in the project, of which 53 (68%) submitted valid reports of suspected adverse drug reactions (ADRs). During the project, a total of 302 valid reports were submitted, and the pharmacists' share in total reporting increased to 74% in 2023 compared to less than 10% in the previous 5 years. The results of this research will be used to make recommendations for further improvement of the pharmacovigilance system, as well as to create plans for continuing education (CE) of other health workers in the area of rational and safe use of medicines.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"13 2","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12030461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors Influencing Community Pharmacists' Participation in Antimicrobial Stewardship: A Qualitative Inquiry. 影响社区药师参与抗菌药物管理的因素:一项定性调查。
IF 2
Pharmacy Pub Date : 2025-04-14 DOI: 10.3390/pharmacy13020056
Tasneem Rizvi, Syed Tabish R Zaidi, Mackenzie Williams, Angus Thompson, Gregory M Peterson
{"title":"Factors Influencing Community Pharmacists' Participation in Antimicrobial Stewardship: A Qualitative Inquiry.","authors":"Tasneem Rizvi, Syed Tabish R Zaidi, Mackenzie Williams, Angus Thompson, Gregory M Peterson","doi":"10.3390/pharmacy13020056","DOIUrl":"https://doi.org/10.3390/pharmacy13020056","url":null,"abstract":"<p><p>Very few studies, all employing surveys, have investigated the perceptions of community pharmacists regarding antimicrobial stewardship (AMS). A qualitative inquiry exploring factors affecting community pharmacists' participation in AMS may assist in the implementation of AMS in the primary care setting. This study aimed to explore the perceived barriers and enablers of community pharmacists' participation in AMS. One-on-one semi-structured telephone interviews were conducted with a sample of community pharmacists from across Australia. Interviews were transcribed verbatim and analysed using the Framework Analysis method. Twenty community pharmacists (70% female), representing urban, regional, and remote areas of Australia participated in the study. Pharmacists identified a discord between clinical needs of patients and practice policies as the primary source of excessive prescribing and dispensing of antibiotics. The fragmented nature of the primary healthcare system in Australia was seen as limiting information exchange between community pharmacists and general practitioners about antibiotic use, that was encouraging inappropriate and, at times, unsupervised use of antibiotics. The existing community pharmacy funding model in Australia, where individual pharmacists do not benefit from any financial incentives associated with clinical interventions, was also discouraging their participation in AMS. Pharmacists suggested restricting default antibiotic repeat supplies, reducing legal validity of antibiotic prescriptions to less than the current 12 months, and adopting a treatment duration-based approach to antibiotic prescribing instead of the 'quantity-based' approach, where the quantity prescribed is linked to the available pack size of the antibiotic. Structural changes in the way antibiotics are prescribed, dispensed, and funded in the Australian primary care setting are urgently needed to discourage their misuse by the public. Modifications to the current funding model for pharmacist-led cognitive services are needed to motivate pharmacists to participate in AMS initiatives.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"13 2","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12030745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heparin-Induced Hyperkalemia Assessment Utilizing the Naranjo Adverse Drug Reaction Probability Scale: A 40-Year Systematic Review. 利用Naranjo药物不良反应概率量表评估肝素诱导的高钾血症:一项40年的系统回顾。
IF 2
Pharmacy Pub Date : 2025-04-11 DOI: 10.3390/pharmacy13020055
Divita Singh, Omnia A E A Mesalhy, Michael J Cawley
{"title":"Heparin-Induced Hyperkalemia Assessment Utilizing the Naranjo Adverse Drug Reaction Probability Scale: A 40-Year Systematic Review.","authors":"Divita Singh, Omnia A E A Mesalhy, Michael J Cawley","doi":"10.3390/pharmacy13020055","DOIUrl":"https://doi.org/10.3390/pharmacy13020055","url":null,"abstract":"<p><strong>Background: </strong>Adverse drug reactions have been reported as leading causes of morbidity and mortality. Unfractionated heparin- and low-molecular-weight heparin-induced hyperkalemia are side effects that have been reported in approximately 7 to 8% of heparin-treated patients. Algorithms, assessment tools, and decision aids are needed to assist in determining the causality of these adverse drug reactions.</p><p><strong>Aim: </strong>The aim of this study was to determine the number of case reports of hyperkalemia resulting from unfractionated heparin or low-molecular-weight heparin use by utilizing the Naranjo Adverse Drug Reaction Probability Scale.</p><p><strong>Methods: </strong>PubMed, International Pharmaceutical Abstracts, and the Cochrane Library were searched for relevant publications. Search terms and Boolean operators, including \"hyperkalemia AND heparin\", \"hyperkalemia AND low molecular weight heparin\", \"heparin AND hypoaldosteronism\", and \"low molecular weight heparin AND hypoaldosteronism\", were used. Searches were limited to case reports and human specimens.</p><p><strong>Results: </strong>A total of 29 case reports were identified, incorporating 38 patient cases. Of the 38 patient cases, 5 [4 involving unfractionated heparin and 1 involving low-molecular-weight heparin] (13.2%) utilized the Naranjo Adverse Drug Reaction Probability Scale to identify the possibility of an adverse drug reaction occurring due to exposure to unfractionated or low-molecular-weight heparin as probable.</p><p><strong>Conclusions: </strong>The available evidence suggests that clinicians' use of the Naranjo Adverse Drug Reaction Probability Scale to determine the potential of hyperkalemia occurring due to exposure to unfractionated heparin and low-molecular-weight heparin is limited. Clinicians should be encouraged to utilize an objective monitoring tool to help standardize assessment of causality for all adverse drug reactions.</p>","PeriodicalId":30544,"journal":{"name":"Pharmacy","volume":"13 2","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12030744/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144062449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating Pharmacy Student Perspectives and Attitudes Towards Compliance Aids and Devices Through Health Disparity Simulation. 通过健康差异模拟评估药学学生对依从性辅助和设备的观点和态度。
IF 2
Pharmacy Pub Date : 2025-04-10 DOI: 10.3390/pharmacy13020054
Bradley Phillips, Jason Powell
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