Ecotoxicology and Environmental Safety最新文献

{"title":"The Hormesis effect of cadmium on Panax notoginseng and corresponding impact on the rhizosphere microorganism","authors":"Mingpeng Liu ,&nbsp;Xuanxiang Du ,&nbsp;Mulan Wang ,&nbsp;Yuewen Huo ,&nbsp;Yanbo Zeng ,&nbsp;Jingheng Wu ,&nbsp;Xin Ying ,&nbsp;Fugang Wei ,&nbsp;Li Liu ,&nbsp;Jianguo Tang","doi":"10.1016/j.ecoenv.2025.117839","DOIUrl":"10.1016/j.ecoenv.2025.117839","url":null,"abstract":"<div><div><em>Panax notoginseng</em> is a famous Chinese traditional medicinal. However, soil cadmium pollution seriously affected the yield and quality of notoginseng. This study systematically investigated the effects of soil Cd stress at different concentrations on the growth of one-year-old notoginseng. The results indicate that Cd exhibits a typical low-dose stimulation and high-dose inhibition effect on the development of notoginseng. At low concentrations (1 mg/kg), Cd promotes the growth of plants, including increased biomass (∼40 % of root dry weight) and higher saponin contents (∼30 % of total saponins). At high concentrations, Cd inhibits the overall growth and metabolism of notoginseng. Meanwhile, the impact of Cd on the rhizospheric micro-environment shows dose dependency. In a low Cd stress environment, the total and unique microbial populations increase, including Rhizobiaceae, Streptomycetaceae, and Mesorhizobium. Conversely, under strong Cd stress, the richness and diversity of the rhizospheric microbial community decrease, while the abundance of cadmium-tolerant species increases, such as Deinococcus and Rhodanobacter.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"291 ","pages":"Article 117839"},"PeriodicalIF":6.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143278591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The interaction between genetic predicted gut microbiome abundance and particulate matter on the risk of incident asthma in adults","authors":"Hehua Zhang ,&nbsp;Yong Feng ,&nbsp;Honghao Yang ,&nbsp;Yuqian Li ,&nbsp;Zheng Ma ,&nbsp;Liuxin Li ,&nbsp;Liangkai Chen ,&nbsp;Yuhong Zhao ,&nbsp;Lishen Shan ,&nbsp;Yang Xia","doi":"10.1016/j.ecoenv.2025.117848","DOIUrl":"10.1016/j.ecoenv.2025.117848","url":null,"abstract":"<div><div>Air pollution and gut microbial abundance (GMA) are both closely related with asthma incidence. This study aims to explore significant interact on the risk of incident asthma in adult exist between GMA and PM_2.5 exposure based on a prospective cohort of UK Biobank. Polygenic score of GMA was calculated using 19 distinct single nucleotide polymorphisms. PM_2.5 exposure was predicted using a validated Land Use Regression model. Incident asthma was identified by linking with medical encounters or first occurrence source. Cox proportional hazards regression models were used to evaluate the associations. Hazard ratios (HRs) and 95 % confidence intervals (CIs) were calculated. During an average follow-up of 11.4 years within 390,054 participants, a total of 11,312 asthma cases occurred with an incidence density of 2.54 per 1000 person years. Participants with the highest PM_2.5 and GMA exposure were associated with a 13 % (HR = 1.13, 95 % CI: 1.05, 1.22; <em>P</em> _{for trend} &lt; 0.001) higher and 16 % (HR = 0.84, 95 %CI: 0.74, 0.94; <em>P</em> _{for trend} &lt; 0.01) lower risk of incident asthma, respectively. A significant negative additive interaction between GMA and PM_2.5 exposure with the risk of incident asthma in adult was found (Relative Excess Risk due to Interaction = −0.08, 95 % CI, −0.16, −0.002). Participants with very high GMA and lowest PM2.5 exposure level were associated with a 26 % (HR = 0.74, 95 % CI: 0.57, 0.96) lower risk of incident asthma. A higher level of GMA has the potential to alleviate the detrimental effect of PM_2.5 exposure on the risk of asthma in adults. Strategies targeting GMA, such as modifying diet and using probiotics supplement may be helpful for preventing asthma derived from PM_2.5 exposure.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"291 ","pages":"Article 117848"},"PeriodicalIF":6.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143278593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined effects of co-exposure to microcystin-LR and polystyrene microplastics on growth, brain pathology and thyroid hormone homeostasis in adult zebrafish","authors":"Wang Lin ,&nbsp;Ling Liao ,&nbsp;Ling Ling ,&nbsp;Huimin Luo ,&nbsp;Ying Jiang ,&nbsp;Xinru Li ,&nbsp;Yilong Yao ,&nbsp;Pinhong Yang","doi":"10.1016/j.ecoenv.2025.117855","DOIUrl":"10.1016/j.ecoenv.2025.117855","url":null,"abstract":"<div><div>The concurrent presence of algal blooms and microplastics pollution in natural water bodies poses a novel threat. However, the joint effects of microcystin-LR (MCLR) in combination with polystyrene microplastics (PSMPs) on the thyroid endocrine system of adult fish remains unclear. In our study, male zebrafish (<em>Danio rerio</em>) were exposed to environmentally relevant concentrations of MCLR alone (0, 0.8, 4, 20 μg/L) and a mix of MCLR and PSMPs (100 μg/L) for 60 days. Alterations in brain histology, thyroid hormone (TH) levels, and the transcription levels of hypothalamic-pituitary-thyroid (HPT)-axis genes were used to assess the thyroid function. In the MCLR-only treatment groups, we observed mild brain tissue damage characterized by glial scarring and hyperemia. The presence of PSMPs exacerbated the brain damage cause by MCLR, resulting in more pronounced ventriculomegaly and hyperemia. No significant changes in whole-body thyroxine (T4) and triiodothyronine (T3) levels were observed in the MCLR-only groups, while a significant decrease was noted in the groups co-exposed to MCLR and PSMPs. Additionally, significant alterations in <em>crh</em>, <em>tshβ</em>, <em>ttr</em> <!-->, <em>trα</em>, and <em>trβ</em> expression levels in the combined exposure groups provided further confirmation that MCLR and PSMPs jointly cause thyroid endocrine disruption. Our findings suggest that the fish can trigger a compensatory mechanism to maintain thyroid hormone homeostasis in response to environmentally relevant concentrations of MCLR. However, the presence of PSMPs disrupts this self-regulatory equilibrium, thereby exacerbates the thyroid endocrine disruption cause by MCLR in zebrafish.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"291 ","pages":"Article 117855"},"PeriodicalIF":6.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143279171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nrf2/cyclooxygenase 2 signaling in Cr(VI)-induced carcinogenesis","authors":"Lei Zhao ,&nbsp;Yi-Fang Wang ,&nbsp;Andrea Adamcakova-Dodd ,&nbsp;Peter S. Thorne ,&nbsp;Ranakul Islam ,&nbsp;Ke Jian Liu ,&nbsp;Fei Chen ,&nbsp;Jia Luo ,&nbsp;Ling-Zhi Liu","doi":"10.1016/j.ecoenv.2025.117800","DOIUrl":"10.1016/j.ecoenv.2025.117800","url":null,"abstract":"<div><div>Long-term exposure to hexavalent chromium [Cr(VI)] has been linked to lung cancer, and cyclooxygenase-2 (COX-2) is a well-known inflammatory factor. However, the role and mechanism of COX-2 in Cr(VI)-induced carcinogenesis are not clear yet. To address this question, we employed a mouse model exposed to Cr(VI) through intranasal instillation of particulate zinc chromate (ZnCrO₄) for 12 weeks. Metabolomics and RNA-seq assays revealed enhanced activity of the arachidonic acid (AA)/eicosanoid metabolism pathway in lung tissues from mice exposed to Cr(VI). COX-2, the key enzyme of the AA/eicosanoid pathway, was significantly upregulated in Cr(VI)-exposed lung tissues, as well as in the Cr(VI)-induced transformed (Cr-T) cells compared to parental BEAS-2B (B2B) cells. We then employed multidisciplinary <em>in vitro</em> and <em>in vivo</em> functional assays to characterize the role of COX-2 in Cr(VI)-induced lung cancer. The results indicated that COX-2 functioned as an oncogene to promote the malignant transformation of B2B cells and enhance the proliferation, migration, tumor growth, and angiogenesis of Cr-T cells. Nuclear factor E2-related factor-2 (Nrf2) was identified as a transcription factor for COX-2. Nrf2 was upregulated in response to Cr(VI) exposure and contributed to Cr(VI)-induced lung cancers, in part by upregulating COX-2 expression. Moreover, microRNA-379 (miR-379) was found to target COX-2 to inhibit its expression posttranscriptionally. MiR-379 was downregulated in Cr(VI)-exposed lung tissues and Cr-T cells, and ectopic miR-379 expression reduced Cr-T cell viability and migration, with partial reversal upon COX-2 restoration. In summary, our study revealed the oncogenic role of COX-2 and identified two novel regulatory mechanisms for COX-2 overexpression in Cr(VI)-induced carcinogenesis.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"291 ","pages":"Article 117800"},"PeriodicalIF":6.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143350514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of iron on improving antimony tolerance in Salvia spinosa","authors":"Shakiba Rajabpoor ,&nbsp;Soghra Kiani ,&nbsp;Shokoofeh Hajihashemi","doi":"10.1016/j.ecoenv.2025.117852","DOIUrl":"10.1016/j.ecoenv.2025.117852","url":null,"abstract":"<div><div>Antimony (Sb) is a potential threat to living organisms, but very little is known on strategies manage its toxicity in plants. This study aimed to clarify the role of Fe on alleviation Sb toxicity in a metallicolous population of <em>Salvia spinose</em> and its mechanisms. With regard to the toxicity of Sb in plants and the importance of Fe potential in alleviation of Sb toxicity, <em>S. spinosa</em> was treated with 0 and 27 mg l⁻¹ Sb (Ш or V) along with 0, 50 and 300 μM FeEDTA in a hydroponic system. The plants exposure to iron minimized the uptake of both Sb species by Salvia roots. The limitation of H₂O₂ generation in response to co-application of Fe with Sb was followed by counterbalancing the antioxidant enzymes (e.g. catalase, superoxide dismutase and ascorbate peroxidase), phenols, flavonoids, lipid membrane preservation, and increase of the carbohydrates and proteins contents, which altogether improved growth in Sb-stressed plants. The Sb (III) toxicity to plants was much higher than Sb (V), but 300 μM Fe was significantly efficient in reducing Sb damages to Salvia. Altogether, application of Fe could efficiently alleviate the physiological and morphological functions in Sb-stressed Salvia.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"291 ","pages":"Article 117852"},"PeriodicalIF":6.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143372294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal exposure to polycyclic aromatic hydrocarbons and blood pressure in the early life of children","authors":"Xiaodong Chen ,&nbsp;Lingling Dong ,&nbsp;Lina Yang ,&nbsp;Yan Yang ,&nbsp;Liyu Yang ,&nbsp;Sijia Han","doi":"10.1016/j.ecoenv.2025.117830","DOIUrl":"10.1016/j.ecoenv.2025.117830","url":null,"abstract":"<div><div>Exposure to polycyclic aromatic hydrocarbons (PAHs) has been associated with many adverse health outcomes. This cohort study investigates the association between prenatal exposure to PAHs and blood pressure in children aged 4–6 years. Conducted in Shenyang, China, the study includes 5642 children whose mothers provided urine samples in the third trimester, which were analyzed for PAH metabolites. Children’s blood pressure indicators, including systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), and pulse pressure (PP), were measured during follow-up. Multivariable regression models, adjusted for key confounders, were used to explore associations between PAH metabolites and blood pressure. Additionally, we applied quantile g-computation (g-comp) and Bayesian kernel machine regression (BKMR) to assess the combined and interaction effects of multiple PAH metabolites. Prenatal exposure to specific PAH metabolites showed significant associations with blood pressure parameters. 2-hydroxynaphthalene, 3-hydroxyfluorene, 9-hydroxyphenanthrene, and 1-hydroxypyrene were positively linked to SBP. For DBP, 2-hydroxynaphthalene, 1-hydroxynaphthalene, and total PAH metabolites revealed strong associations. PP was significantly linked to 3-Hydroxyfluorene, while MAP showed consistent associations with 2-hydroxynaphthalene, 1-hydroxynaphthalene, 9-hydroxyphenanthrene, and 1-hydroxypyrene. G-comp analysis revealed significant associations between prenatal PAH exposure and increases in SBP, DBP, and MAP, with no effect on PP. BKMR showed no strong evidence for SBP or DBP but suggested potential positive associations for PP and MAP at higher exposure quantiles, indicating nuanced, exposure-dependent relationships with blood pressure outcomes. This study, being one of the first to explore these associations in children, provides important insights into the potential long-term health impacts of prenatal PAH exposure on childhood cardiovascular health.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"291 ","pages":"Article 117830"},"PeriodicalIF":6.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential risk of heavy metals release in sediments and soils of the Yellow River Basin (Henan section): A perspective on bioavailability and bioaccessibility","authors":"Peng Wang ,&nbsp;Furong Yu ,&nbsp;Haonan Lv ,&nbsp;Lin Wu ,&nbsp;Hui Zhou","doi":"10.1016/j.ecoenv.2025.117799","DOIUrl":"10.1016/j.ecoenv.2025.117799","url":null,"abstract":"<div><div>The ecology of watersheds plays an important role in regulating regional climate and human activities. The sediment-soil system in the middle and lower reaches of the Yellow River Basin (Henan section) was explored. The spatial distribution characteristics of heavy metals (HMs) showed that tributaries, which are affected by anthropogenic activities, contain higher concentrations of HMs than the main channel. Sequential extraction experiments indicated that Cd had the strongest potential to be released, followed by Mn. In vitro simulation experiments showed that gastric and pulmonary fluids rendered these two orders of magnitude more bioaccessible compared to sweat. Moreover, Cd exhibited the highest bioaccessibility in both gastric and lung fluids. When bioaccessibility was considered in the evaluation of health risks, more than 82 % of reductions in non-carcinogenic and carcinogenic risk indices were observed in children and adults. A positive matrix factorization model was utilized to determine the potential sources of HMs: industrial sources, natural sources, and mixed agricultural and transportation sources were identified as the three main sources of HMs in sediments and soils. In addition, mining activities were also an HMs source in sediments.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"291 ","pages":"Article 117799"},"PeriodicalIF":6.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143057467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection and collection of shiga toxin-producing Escherichia coli using foam concentration without membrane filtration","authors":"Soichiro Tamai,&nbsp;Makoto Katafuchi,&nbsp;Xie Hui,&nbsp;Yoshihiro Suzuki","doi":"10.1016/j.ecoenv.2025.117797","DOIUrl":"10.1016/j.ecoenv.2025.117797","url":null,"abstract":"<div><div>Information on Shiga toxin-producing <em>Escherichia coli</em> (STEC) in river water is scarce, and it is essential to understand its actual status in river water. This study investigated a method for the highly efficient recovery of STEC from river water in its active state by combining a coagulation and foam concentration and a selective medium. The method was applied to three rivers, and STEC-positive <em>Escherichia coli</em> (<em>E. coli</em>) were obtained from all rivers. Ten <em>E. coli</em> harboring one of the pathogenic genes (<em>stx2</em>, <em>eae</em>) were detected in the Oyodo River’s upstream and midstream and the Kaeda River’s midstream. Furthermore, antimicrobial agent susceptibility testing was performed on these ten strains using ten antimicrobial agents. Nine strains showed intermediate resistance to at least one antibiotic, and one was multidrug-resistant. This study’s coagulation and foam concentration and selective medium detection methods can efficiently collect STEC in river water and recover it in an active state without conventional membrane filtration. Isolating and cultivating this STEC strain will provide crucial information for antimicrobial agent susceptibility testing, target gene testing, and whole-genome analysis.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"291 ","pages":"Article 117797"},"PeriodicalIF":6.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biodegradation of CAHs and BTEX in groundwater at a multi-polluted pesticide site undergoing natural attenuation: Insights from identifying key bioindicators using machine learning methods based on microbiome data","authors":"Feiyang Xia,&nbsp;Tingting Fan,&nbsp;Mengjie Wang,&nbsp;Lu Yang,&nbsp;Da Ding,&nbsp;Jing Wei,&nbsp;Yan Zhou,&nbsp;Dengdeng Jiang,&nbsp;Shaopo Deng","doi":"10.1016/j.ecoenv.2024.117609","DOIUrl":"10.1016/j.ecoenv.2024.117609","url":null,"abstract":"<div><div>Groundwater pollution, particularly in retired pesticide sites, is a significant environmental concern due to the presence of chlorinated aliphatic hydrocarbons (CAHs) and benzene, toluene, ethylbenzene, and xylene (BTEX). These contaminants pose serious risks to ecosystems and human health. Natural attenuation (NA) has emerged as a sustainable solution, with microorganisms playing a crucial role in pollutant biodegradation. However, the interpretation of the diverse microbial communities in relation to complex pollutants is still challenging, and there is limited research in multi-polluted groundwater. Advanced machine learning (ML) algorithms help identify key microbial indicators for different pollution types (CAHs, BTEX plumes, and mixed plumes). The accuracy and Area Under the Curve (AUC) achieved by Support Vector Machines (SVM) were impressive, with values of 0.87 and 0.99, respectively. With the assistance of model explanation methods, we identified key bioindicators for different pollution types which were then analyzed using co-occurrence network analysis to better understand their potential roles in pollution degradation. The identified key genera indicate that oxidation and co-metabolism predominantly drive dechlorination processes within the CAHs group. In the BTEX group, the primary mechanism for BTEX degradation was observed to be anaerobic degradation under sulfate-reducing conditions. However, in the CAHs&amp;BTEX groups, the indicative genera suggested that BTEX degradation occurred under iron-reducing conditions and reductive dechlorination existed. Overall, this study establishes a framework for harnessing the power of ML alongside co-occurrence network analysis based on microbiome data to enhance understanding and provide a robust assessment of the natural attenuation degradation process at multi-polluted sites.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"291 ","pages":"Article 117609"},"PeriodicalIF":6.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uptake kinetics and distribution of flupyrimin by rice (Oryza sativa L.): Effects of subcellular fractionation and soil factors","authors":"Xugen Shi ,&nbsp;Min Wang ,&nbsp;Zhenyu Jiang ,&nbsp;Ruqiang Cui ,&nbsp;Baotong Li ,&nbsp;Xianpeng Zhang ,&nbsp;Lianhu Zhang ,&nbsp;Duantao Cao","doi":"10.1016/j.ecoenv.2025.117810","DOIUrl":"10.1016/j.ecoenv.2025.117810","url":null,"abstract":"<div><div>Flupyrimin is an emerging neonicotinoid insecticide primarily used to control rice planthoppers. However, knowledge gaps exist regarding its uptake and transport in rice planting systems. Elucidating the absorption and distribution properties of flupyrimin in rice will help assess the potential risks of human exposure to flupyrimin via the food chain. Here, we studied the uptake kinetics and transport mechanisms of flupyrimin in rice plants grown under hydroponic and soil conditions. The hydroponic experiment indicated that flupyrimin was easily taken up by rice roots via a symplastic passive diffusion process and was mainly distributed in the cell soluble fractions (50.6 %－88.0 %). Compared with transportation from the roots to the stems, flupyrimin was ultimately transported from the stems to the leaves with a greater translocation factor (TF) (TF_Leave/Stem = 27.8 &gt; TF_Stem/Root = 3.1). In rice-soil systems, the accumulation of flupyrimin by rice plants is influenced primarily by the soil organic matter content, which leads to increased adsorption of flupyrimin onto soils (R² &gt; 0.897, <em>P</em> &lt; 0.014). Interestingly, the concentration of flupyrimin in rice was significantly positively correlated with its amount in the soil pore water (C_IPW) (R² &gt; 0.967, <em>P</em> &lt; 0.003), indicating that the uptake and accumulation of flupyrimin in rice planting systems can be estimated by C_IPW. These findings enhance our knowledge of flupyrimin absorption and distribution in rice plants from treated soils and are important for guiding its field application and conducting environmental risk assessments.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"291 ","pages":"Article 117810"},"PeriodicalIF":6.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}