Ecotoxicology and Environmental Safety最新文献

{"title":"Bioaerosol emission and exposure risk from a wastewater treatment plant in winter and spring","authors":"Yulei Zhao ,&nbsp;Mingyu Xiong ,&nbsp;Kinfai Ho ,&nbsp;Yongfang Rao ,&nbsp;Yu Huang ,&nbsp;Junji Cao ,&nbsp;Yang Yue ,&nbsp;Jing Wang ,&nbsp;Gang Wen ,&nbsp;Juntang Li","doi":"10.1016/j.ecoenv.2024.117294","DOIUrl":"10.1016/j.ecoenv.2024.117294","url":null,"abstract":"<div><div>The potential health risks posed by bioaerosols containing pathogens originating from wastewater treatment plants (WWTPs) have gaining intensive attention. This study designated sampling locations within a WWTP situated in Xi'an, a major city in northwest China. The airborne bacterial concentration, taxonomic composition, and the associated health risks were analyzed in the aeration tanks with bottom microporous aeration system. The Anaerobic-Anoxic-Oxic (AAO) tank emitted significantly higher culturable bacteria (1.58×10⁴ CFU m⁻³ in spring, 6.69×10³ CFU m⁻³ in winter) compared to Double-ditch (DE) oxidation ditch and aerated grit chamber (AGC) chamber, aligning with 16S rDNA quantification results. The bacterial concentrations are higher in spring than that in winter, with the AAO tank posing the highest exposure risk during the spring season. The dominant genera in the air samples include <em>Cutibacterium</em>, <em>Lawsonella</em>, <em>Acinetobacter</em>, <em>Pseudomonas</em>, and <em>Aeromonas</em>. Among the identified genus, 139 bacterial genera were identified as potential human pathogens like <em>Neisseria, Moraxella, Haemophilus, Escherichia-Shigella</em> and <em>Streptococcus.</em> These pathogens further elevate exposure risks from WWTP bioaerosols. This study provides relevant information on the seasonal health risk variations tied to bioaerosol emissions from diverse aeration tanks with bottom microporous aeration system in the mega city of northwest China, emphasizing the imperative to enhance the management and control measures for bioaerosols originating from the AAO tank.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"287 ","pages":"Article 117294"},"PeriodicalIF":6.2,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aristolochic acid-induced dyslipidemia and hepatotoxicity: The potential role of FXR and AHR receptors","authors":"Yumei Ma ,&nbsp;Chenlong Du ,&nbsp;Yuzhen Liu ,&nbsp;Meiyao Feng ,&nbsp;Yingqing Shou ,&nbsp;Dianke Yu ,&nbsp;Yuan Jin","doi":"10.1016/j.ecoenv.2024.117266","DOIUrl":"10.1016/j.ecoenv.2024.117266","url":null,"abstract":"<div><div>Aristolochic acids (AAs) represent a class of nitrophenanthrene carboxylic acids naturally existing or accidentally mixed in herbal medicines or crops, which have long been recognized for causing nephropathy. Recently, the linkage between AAs and liver injury has become a concern; however, the current understanding of the mechanism or mode of action (MOA) is limited. In the present study, we investigated nuclear receptor-mediated MOA associated with AAs-induced liver injury including dyslipidemia and hepatotoxicity. Bioinformatic analysis of AAI-interacting genes indicated nuclear receptor-mediated metabolizing pathways; Transcriptomic profiling of AAs-exposed rats with liver injury suggested FXR-, NRF2-, and AHR- mediated pathways in the injured livers of the rats. Mechanistic investigation using HepG2 cells indicated AAI-induced hepatic lipid accumulation by elevating Triglyceride (TG) through inhibition of the FXR. In addition, AAI-induced hepatocellular damage by activating the AHR pathway, which further generated ROS and activated the NRF2 pathway. Together, these results provided new clues for researchers who are interested in chemical-induced liver injury.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"287 ","pages":"Article 117266"},"PeriodicalIF":6.2,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142594039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microplastics in maternal blood, fetal appendages, and umbilical vein blood","authors":"Hanxiang Sun ,&nbsp;Xiujuan Su ,&nbsp;Jing Mao ,&nbsp;Yang Liu ,&nbsp;Guohua Li ,&nbsp;Qiaoling Du","doi":"10.1016/j.ecoenv.2024.117300","DOIUrl":"10.1016/j.ecoenv.2024.117300","url":null,"abstract":"<div><div>Microplastics (MPs) have been detected in placenta and amniotic fluid, but there is no research on whether MPs exist in the other two fetal appendages: fetal membrane and umbilical cord. Additionally, the existence of MPs in umbilical vein blood remains unexplored. Furthermore, it is unclear whether MPs in maternal blood are associated with those in umbilical vein blood and fetal appendages. In this study, we selected 12 full-term pregnant people who delivered by cesarean section, and finally detected 16 kinds of MPs from maternal blood, fetal appendages, and umbilical vein blood by laser direct infrared (LDIR). Polyamide accounted for the highest proportion in the six kinds of samples, followed by Polyurethane. The total MPs median abundance in six kinds of samples were umbilical cord, maternal blood, fetal membrane, amniotic fluid, placenta and umbilical vein blood from high to low, and the specific values were 10.397 particles/g, 8.176 particles/g, 6.561 particles/g, 4.795 particles/g, 4.675 particles/g, and 2.726 particles/g respectively. Moreover, more than 90 % of MPs measured between 20 and 100 μm in diameter. We also found that MPs abundance in amniotic fluid increased with the increase of maternal age (R=0.64, <em>p</em>=0.025) and body mass index before pregnancy (r = 0.59, <em>p</em>= 0.049). However, no statistically significant association was found between lifestyle factors and MPs abundance. Future studies should aim to expand the sample size for further investigation.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"287 ","pages":"Article 117300"},"PeriodicalIF":6.2,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142594038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global trends and projections of occupational trichloroethylene (TCE) exposure-associated kidney cancer: Insights of the Global Burden of Disease (GBD) Study 2021 from 1990 to 2021 and prediction to 2050","authors":"Hang Huang ,&nbsp;Ping Li ,&nbsp;Haoran Jiang ,&nbsp;Junkai Hong ,&nbsp;Yongyong Lu","doi":"10.1016/j.ecoenv.2024.117252","DOIUrl":"10.1016/j.ecoenv.2024.117252","url":null,"abstract":"<div><h3>Background</h3><div>Exposure to trichloroethylene (TCE) in occupations is associated with an increased risk of kidney cancer (KC). However, there is a lack of comprehensive study on the global burden of occupational exposure to TCE-related KC.</div></div><div><h3>Methods</h3><div>Epidemiological data on occupational TCE exposure-associated KC from 1990 to 2021 were obtained from Global Burden of Disease (GBD) 2021 study, including death counts and disability-adjusted life years (DALYs). Global burden of this disease was stratified by genders, age, socio-demographic index (SDI) quintiles, GBD subcontinental regions, and countries. The estimated annual percentage change (EAPC) was calculated to illustrate trends over the last 32 years, and forecasts were conducted to predict the disease burden until 2050.</div></div><div><h3>Results</h3><div>In 2021, the global age-standardized death rate (ASDR) of occupational TCE exposure-related KC was 0.0009 (95 %UI: 0.0002–0.0016) per 100,000 persons, and the age-standardized DALY rate (ASDAR) was 0.0284 (95 %UI: 0.0062–0.0522) per 100,000 individuals. The disease showed significant heterogeneity by sex and age, with males bearing a notably higher burden, and the burden being concentrated in the 50–79 year-old group. Major burdens were focused in middle to high-middle SDI regions, especially in Southern Latin America (Uruguay, Argentina, and Chile). Over 32 years, the burden of occupational TCE exposure-associated KC has gradually increased, with projections indicating continued growth to 2050, particularly among males and individuals aged 50–79. Regions like high-middle SDI areas, North America, High-income North America, Southern Sub-Saharan Africa, saw the most significant increases. Correlation analyses indicated a positive association between ASDR and ASDAR with SDI, while EAPC showed a notable negative correlation with SDI. Decomposition analyses reveals three global population determinants that positively contributed to the increase in deaths, but negatively impacted DALYs.</div></div><div><h3>Conclusion</h3><div>This study highlights a significant rising trend of occupational TCE exposure-associated KC from 1990 to 2021 and projected to 2050, with an emphasis on the disease burden in men, elderly population, and middle to high-middle SDI regions, underscoring the impact of occupational TCE exposure on KC.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"287 ","pages":"Article 117252"},"PeriodicalIF":6.2,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between per-fluoroalkyl and polyfluoroalkyl substance exposure and insulin resistance in nondiabetic adults: Evidence from NHANES 2003–2018","authors":"Peng Jia ,&nbsp;Xinwen Yu ,&nbsp;Yuxin Jin ,&nbsp;Xin Wang ,&nbsp;Aili Yang ,&nbsp;Li Zhang ,&nbsp;Xiaorui Jing ,&nbsp;Weiwei Kang ,&nbsp;Guohong Zhao ,&nbsp;Bin Gao","doi":"10.1016/j.ecoenv.2024.117260","DOIUrl":"10.1016/j.ecoenv.2024.117260","url":null,"abstract":"<div><h3>Background</h3><div>Studies have linked per- and polyfluoroalkyl substances (PFAS) to chronic metabolic diseases. However, the relationship between PFAS exposure and insulin resistance (IR), a key pathophysiological basis of these metabolic diseases, in nondiabetic individuals have yet to be determined.</div></div><div><h3>Methods</h3><div>This study analyzed data from 3909 participants (aged ≥20) from the NHANES 2003–2018 to investigate the associations between serum levels of seven PFAS and and IR indicators, including including HOMA-IR, HOMA-β, fasting insulin, QUICKI, and TyG index. Linear and logistic regression models were used, along with a restricted cubic spline to assess dose-response. Weighted quantile sum (WQS) regression and quantile g-computation (qgcomp) models were used to assess the association between mixed PFAS exposure and IR.</div></div><div><h3>Results</h3><div>Linear regression revealed that elevated exposure to PFOS [β (95 % CI): 0.04 (0.02, 0.06)], PFOA [0.04 (0.01, 0.06)], and Me_PFOSA_AcOH [0.04 (0.02, 0.06)] was associated with a higher TyG index in adults. Notably, Me_PFOSA_AcOH was negatively associated with IR when assessed by HOMA-IR &gt;2.6 [OR (95 % CI): 0.88 (0.79, 0.98)], although this was not supported by linear regression findings. When IR was defined by a TyG index &gt;8.6, exposure to the highest quartiles of PFOS, PFOA, and Me_PFOSA_AcOH was associated with an increased risk of IR by 63 %, 42 %, and 85 %, respectively [1.63 (1.21, 2.20); 1.42 (1.06, 1.92); 1.85 (1.37, 2.50)]. PFOS, PFOA, and Me_PFOSA_AcOH demonstrated a nonlinear dose-response relationship with IR risk. The WQS and qgcomp models revealed significant positive correlations with the TyG index.</div></div><div><h3>Conclusion</h3><div>Mixed PFAS exposure in US nondiabetic adults was positively associated with IR, as indicated by the TyG index, particularly for PFOS, PFOA, and Me_PFOSA_AcOH. Further research is needed to establish causality, and reinforcing environmental risk mitigation strategies to reduce PFAS exposure is recommended.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"287 ","pages":"Article 117260"},"PeriodicalIF":6.2,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Triglyceride-glucose Index and Its combination with obesity indicators mediating the association between 2-hydroxyfluorene and the prevalence of cardiovascular disease: Evidence from the NHANES (2005–2018)","authors":"Qingsong Mao ,&nbsp;Xiaoyi Zhu ,&nbsp;Xinyi Zhang ,&nbsp;Yuzhe Kong","doi":"10.1016/j.ecoenv.2024.117283","DOIUrl":"10.1016/j.ecoenv.2024.117283","url":null,"abstract":"<div><h3>Background</h3><div>Polycyclic aromatic hydrocarbons (PAHs) were increasingly recognized as a group of environmental pollutants associated with various health issues. The rise in their prevalence in the environment was concerning. Yet, the effects of PAH exposure on cardiovascular diseases (CVDs) were still not well understood.</div></div><div><h3>Purpose</h3><div>This study investigated the impact of exposure to 2-hydroxyfluorene on CVDs prevalence, with a special focus on the mediating role of triglyceride-glucose (TyG) index and its combination with obesity indicators.</div></div><div><h3>Method</h3><div>Using National Health and Nutrition Examination Survey (NHANES) data from 2005 to 2018, this study assessed how 2-hydroxyfluorene affects CVDs prevalence through various statistical techniques. The investigation began with restricted cubic spline (RCS) analysis to explore the relationship between 2-hydroxyfluorene levels and CVDs prevalence. Logistic regression was then used to examine associations within PAH mixtures, alongside the Bayesian Kernel Machine Regression (BKMR) model. Furthermore, the Quantile G-Computation (QG-comp) model was used to evaluate the influence of weights and directions. A mediation analysis was also performed to assess the mediating role of TyG-related indicators on the relationship between 2-hydroxyfluorene and CVDs prevalence. Besides, the association between 2-hydroxyfluorene and the prevalence of each specific CVDs, congestive heart failure, myocardium infarction, angina pectoris and coronary heart disease, was also assessed and so was the mediated effect. Finally, the subgroup analysis was conducted to assess the association in each specific subgroup.</div></div><div><h3>Result</h3><div>The study, involving 3645 participants, found a significant positive association between 2-hydroxyfluorene exposure and CVD (OR (95 %CI) = 115.8013 (5.0521 ∼ 2654.3248), <em>P</em>=0.0029), with 2-hydroxyfluorene showing the positive contribution to CVDs prevalence within the phthalate mixture. The positive association also existed between 2-hydroxyfluorene and the prevalence of each specific CVDs. TyG and TyGWC (Triglyceride Glucose-Waist Circumference) were identified as mediators in the link between 2-hydroxyfluorene exposure and the prevalence of total CVD and each specific CVD, while TyGBMI (Triglyceride Glucose-Body Mass Index) can only mediate the association between 2-hydroxyfluorene and the prevalence of total CVD, congestive heart failure and angina pectoris</div></div><div><h3>Conclusion</h3><div>The findings highlighted a significant association between 2-hydroxyfluorene exposure and CVDs prevalence, with TyG-related indicators acting as mediators.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"287 ","pages":"Article 117283"},"PeriodicalIF":6.2,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"piRNA array analysis provide insight into the mechanism of DEHP-induced testicular toxicology in pubertal male rats","authors":"Guoqing Fu ,&nbsp;Qinru Wu ,&nbsp;Juan Dai ,&nbsp;Siqi Lu ,&nbsp;Ting Zhou ,&nbsp;Zhongcheng Yang ,&nbsp;Yuqin Shi","doi":"10.1016/j.ecoenv.2024.117282","DOIUrl":"10.1016/j.ecoenv.2024.117282","url":null,"abstract":"<div><div>Di-(2-ethylhexyl) phthalate (DEHP), a widely used plasticizer, could cause male reproductive toxicity by disrupting spermatogenesis. Piwi-interacting RNAs (piRNAs) are a small non-coding RNAs specifically highly expressed in the germline and interact with PIWI proteins to regulate spermatogenesis. Accumulating studies have confirmed that environmental poisons could induce male reproductive injury via altering piRNA expression. However, it remains unclear whether DEHP causes male reproductive dysfunction by perturbing piRNA expression levels. In this study, we conducted piRNA microarray expression analyses on testes of DEHP-exposed and control male rats and performed some <em>in vitro</em> and <em>in vivo</em> studies to explore the role of piRNA on DEHP-induced male reproductive toxicity. Our results showed that DEHP exposure leaded to changed expression profiles of piRNAs in pubertal male rat testes. And bioinformatics analyses revealed that down-regulated piR-rno-26751 probably targeted <em>Insr</em> mRNA expression regulation. Results from gene and protein expression tests demonstrated that DEHP caused decreased expression level of INSR mainly in spermatogonia. Moreover, MEHP, the main metabolite of DEHP resulted in cell apoptosis and down-regulation of INSR and its downstream p-IRS1, p-PI3K, p-AKT and p-FOXO1 in GC-1spg cells. Conversely, overexpression of INSR restored cell apoptosis and the down-regulation of the above proteins in GC-1spg cells. In conclusion, these findings suggest that DEHP-induced down-regulation of piR-rno-26751 targets the suppression of INSR, leading to apoptosis of spermatogonia in pubertal male rats.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"287 ","pages":"Article 117282"},"PeriodicalIF":6.2,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Big data from population surveys and environmental monitoring-based machine learning predictions of indoor PM2.5 in 22 cities in China","authors":"Yanjun Du ,&nbsp;Yingying Zhang ,&nbsp;Yaoling Li ,&nbsp;Qiang Huang ,&nbsp;Yanwen Wang ,&nbsp;Qing Wang ,&nbsp;Runmei Ma ,&nbsp;Qinghua Sun ,&nbsp;Qin Wang ,&nbsp;Tiantian Li","doi":"10.1016/j.ecoenv.2024.117285","DOIUrl":"10.1016/j.ecoenv.2024.117285","url":null,"abstract":"<div><div>Many studies have confirmed that PM_2.5 exposure can cause a variety of diseases. Because people spend most of their time indoors, exposure to PM_2.5 in indoor environments is critical to population health. Large-population, long-term, continuous, and accurate indoor PM_2.5 data are important but scarce because of the difficulties in monitoring the indoor air quality on a large scale. Model simulation provides a new research direction. In this study, an advanced machine learning model was constructed using environmental health big data to predict the daily indoor PM_2.5 concentration data in 22 typical air pollution cities in China from 2013 to 2017. The test R² value of this model reached as high as 0.89, and the RMSE of the model was 9.13. The predicted annual indoor PM_2.5 concentrations of the cities ranged from 54.6 μg/m³ to 82.7 μg/m³, and showed a decreasing trend year by year. The pollution level exceeds the recommended AQG level of PM_2.5 and has potential impact on human health. The results could take a breakthrough in obtaining accurate big data of indoor PM_2.5 and contribute to research on the indoor air quality and human health in China.</div></div><div><h3>Synopsis</h3><div>This study established a machine learning model and predicted indoor PM_2.5 big data, which could support the research of indoor PM_2.5 and health.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"287 ","pages":"Article 117285"},"PeriodicalIF":6.2,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on the enhancement effect of EDTA and oxalic acid on phytoremediation of Cr(VI) from soil using Datura stramonium L.","authors":"Cong Shi ,&nbsp;Juan Lv ,&nbsp;Ziying Pei ,&nbsp;Haitao Wang ,&nbsp;Na Chang ,&nbsp;Xin Fang ,&nbsp;Kefan Wang","doi":"10.1016/j.ecoenv.2024.117272","DOIUrl":"10.1016/j.ecoenv.2024.117272","url":null,"abstract":"<div><div>This study investigated the enhancing effects of soil treatment with ethylene diamine tetraacetic acid (EDTA) and oxalic acid (OA) on the remediation of Cr(VI) contaminated soil by <em>Datura stramonium</em> L. A greenhouse pot experiment was conducted, where Cr(VI) contaminated soil was treated with 100 mg/kg Cr(VI) and varying concentrations of EDTA (5 and 10 mmol/kg) and OA (5 and 10 mmol/kg). The effects of these soil treatments on biomass, chlorophyll content, antioxidant enzyme activities, and Cr(VI) enrichment and translocation efficiency of <em>D. stramonium</em> were evaluated. The results showed that added OA to soil significantly increased the biomass and chlorophyll content of <em>D. stramonium</em>. The addition of 10 mmol/kg of OA to soil increased the plant biomass by 67.16 % and chlorophyll b content by 40.01 %. In addition, OA soil treatment significantly enhanced the activities of superoxide dismutase (SOD) by 6.36 %, peroxidase (POD) by 163.13 %, catalase (CAT) by 36.92 %, and ascorbate peroxidase (APX) by 32.12 %, which effectively alleviated the oxidative stress induced by Cr(VI). In contrast, soil treatment with a high concentration of EDTA (10 mmol/kg) significantly reduced plant biomass and chlorophyll content, although it increased the biological concentration factor (BCF) of the stem and leaf, as well as the translocation factor (TF). In conclusion, appropriate amounts of EDTA and OA added to soil can enhance the phytoremediation efficiency of <em>D. stramonium</em> grown in Cr(VI) contaminated soil, with OA added to soil being more effective than addition of EDTA. This study revealed the potential mechanisms of chelating agents EDTA and OA in enhancing the phytoremediation of Cr(VI) contaminated soil by <em>D. stramonium</em>, providing a scientific basis for further optimization of phytoremediation techniques.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"287 ","pages":"Article 117272"},"PeriodicalIF":6.2,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142579033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of microplastics on dissipation of oxytetracycline and its relevant resistance genes in soil without and with Serratia marcescens: Comparison between biodegradable and conventional microplastics","authors":"Guixiang Zhang ,&nbsp;Rui Ren ,&nbsp;Xiurong Yan ,&nbsp;Hongyu Zhang ,&nbsp;Yuen Zhu","doi":"10.1016/j.ecoenv.2024.117235","DOIUrl":"10.1016/j.ecoenv.2024.117235","url":null,"abstract":"<div><div>The biodegradable (polybutylene adipate terephthalate: PBAT) and conventional (polyethylene: PE) microplastics (MPs) at 0.5 %, 1 %, and 2 % dosages (w/w) were added into soils with and without <em>Serratia marcescens</em> ZY01 (ZY01, a <em>tet</em>-host strain) to understand their different effects on the dissipation of oxytetracycline (OTC) and <em>tet</em>. The results showed that the dosages of PBAT MP exhibited different inhibition degrees of OTC biodegradation in soils regardless of ZY01, while the dosages of PE MP did not change the enhancement degree of OTC biodegradation in soils without ZY01. These differences were due to the higher adsorption capacity of OTC on PBAT MP and the stronger toxicity of PBAT MP to microorganisms. Besides soil organic matter, pH and total phosphorus were important factors regulating specific <em>tet</em>-host bacteria in soils with MPs (e.g., the nitrogen-cycling bacteria <em>Steroidobacter</em> and <em>Nitrospira</em>) and MPs + ZY01 (e.g., the phosphorus-cycling bacteria <em>Saccharimonadales</em> and <em>Haliangium</em>), respectively. Regardless of ZY01, a stronger selective harboring of <em>tet</em>-host bacteria in PE MP treatments than PBAT MP treatments was observed at the MP dosage of 1 % (w/w), while the opposite trend was true at the MP dosages of 0.5 % and 2 % (w/w). Some specific genera belonging to Actinobacteriota strongly associated with the class 1 integron-integrase gene (<em>intI1</em>), playing a critical role in the horizontal gene transfer of <em>tet</em> in soils especially for the co-existence of MPs and ZY01. This study will be helpful for understanding on how biodegradable and conventional MPs as hotspots affect the environmental behavior of antibiotics and ARGs in soil.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"287 ","pages":"Article 117235"},"PeriodicalIF":6.2,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142579035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}