Ecotoxicology and Environmental Safety最新文献

{"title":"Effects of benzotriazoles UV-328, UV-329, and UV-P on the self-renewal and adipo-osteogenic differentiation of human mesenchymal stem cells.","authors":"Yue Zhang, Hui Zhao, Qianxi Feng, Rui Guo, Li Zhong, Shengxian Liang","doi":"10.1016/j.ecoenv.2025.117765","DOIUrl":"https://doi.org/10.1016/j.ecoenv.2025.117765","url":null,"abstract":"<p><p>Benzotriazole ultraviolet stabilizers (BUVSs) are pervasive environmental contaminants that pose significant risks to human health. This study evaluated the effects of three typical BUVSs (UV-328, UV-329, and UV-P) on human mesenchymal stem cells (hMSCs), which play crucial roles in tissue maintenance and repair. hMSCs were exposed to BUVSs across a range of concentrations, and their maintenance and differentiation capacities were assessed. At concentrations below 50 μM, no significant cytotoxicity was observed. However, at non-cytotoxic doses, UV-P exhibited stronger effects on the differentiation of hMSCs compared to UV-328 and UV-329, significantly inhibiting adipogenesis and enhancing osteogenesis. Mechanistically, UV-P was found to significantly enrich the PPAR signaling pathway during both differentiation processes. Dual-luciferase reporter assays confirmed UV-P's interaction with PPARγ_LBD at an alternate binding site outside the canonical pocket. These findings raise concerns about the health impacts of BUVSs, particularly UV-P, and underscore the need for further investigation into their toxicological profiles.</p>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"290 ","pages":"117765"},"PeriodicalIF":6.2,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal exposure to tris (2-butoxyethyl) phosphate induces F0 female reproductive toxicity and offspring developmental toxicity in zebrafish.","authors":"Anqi Dong, Wenqian Lei, Weiqi Zhou, Wenwen Li, Jianghua Wang","doi":"10.1016/j.ecoenv.2025.117781","DOIUrl":"https://doi.org/10.1016/j.ecoenv.2025.117781","url":null,"abstract":"<p><p>The toxicity of tris (2-butoxyethyl) phosphate (TBOEP) has been extensively investigated because of its prevalence in the environment. Nevertheless, the risk factors associated with maternal transmission are poorly understood. In this study, sexually mature female zebrafish were treated with TBOEP (0, 20, 100, and 500 μg/L) for 30 days and were mated with unexposed males. Reproduction impairment in exposed adults (F0), including retarded gonado-somatic index (GSI), delayed oocyte maturation, inhibition of reproductive behavior, and subfertility was found. The observed impacts on the F0 generation were linked to a marked decrease in 17β-estradiol concentrations and disruptions in the gene expression patterns along the hypothalamic-pituitary-gonadal-liver (HPGL) axis. Moreover, the accumulation of TBOEP in F0 and their embryos (F1) was observed, indicating significant maternal transfer of TBOEP to the offspring. In F1 larvae, a dose-dependent increase in developmental toxicity (decreased heart rate and swimming behavior, increased larval mortality, and deformity) was observed. Additionally, a notable reduction in protein level in eggs and the gene expression of both the hormone/insulin-like growth factor (GH/IGF) and hypothalamic-pituitary-thyroid (HPT) pathways were observed. These results indicated that subacute TBOEP exposure could induce reproductive toxicity in female zebrafish and cause transgenerational toxicity in their offspring via maternal transfer.</p>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"290 ","pages":"117781"},"PeriodicalIF":6.2,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring chitin metabolite profiles and sensitivity differences in Collembola species exposed to teflubenzuron.","authors":"Saúl Fernandes, Diana Ilyaskina, Matty P Berg, Marja H Lamoree, Pim E G Leonards, Cornelis A M van Gestel","doi":"10.1016/j.ecoenv.2025.117774","DOIUrl":"https://doi.org/10.1016/j.ecoenv.2025.117774","url":null,"abstract":"<p><p>Effective environmental risk assessments of chemical plant protection products, such as benzoylurea pesticides, are crucial for safeguarding ecosystems. These pesticides, including teflubenzuron, target chitin synthesis in arthropods but also pose risks to non-target soil fauna like Collembola, which play essential roles in decomposition and nutrient cycling. This study combines traditional toxicity tests with a metabolomic approach to examine the interspecies specific sensitivity of three Collembola species - Sinella curviseta, Ceratophysella denticulata, and Folsomia candida - to teflubenzuron. The investigation focused on reproduction, bioaccumulation, and changes in chitin-related metabolites as indicators of pesticide impacts. Results revealed significant interspecies specific variability in sensitivity, with F. candida showing higher susceptibility towards teflubenzuron, possibly due to greater bioaccumulation factors. Metabolomic analysis highlighted distinct patterns in chitin metabolite alterations among the species, correlating with their differential sensitivity. Notably, metabolites like trehalose and glucose, crucial for chitin synthesis, were significantly affected by teflubenzuron within seven days of exposure. Despite high soil concentrations of the pesticide, S. curviseta demonstrated resilience in traditional life-history endpoints, such as reproduction and survival. However, metabolomics indicated a biochemical response to even low internal concentrations of teflubenzuron, underscoring the complexity of their interactions with environmental stressors. This study emphasizes the importance of incorporating metabolomics to understand the differential responses of non-target organisms to pesticides and advocates for species-specific risk assessments in pesticide regulation. The distinct metabolic responses among Collembola species to chitin synthesis inhibitors provide critical insights into their ecological resilience or vulnerability, enhancing our understanding of ecosystem dynamics and the potential ramifications of chemical exposure.</p>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"290 ","pages":"117774"},"PeriodicalIF":6.2,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strategies of physiological, morpho-anatomical and biochemical adaptation in seedlings of native species exposed to mining waste.","authors":"Belén Heredia, Pablo Diaz Recio, Brian Jonathan Young, Pablo Pacheco, Franco Barcelo Zungre, Silvina Hruby, Maria Andreína Acevedo, María Inés Mercado, Gonzalo Roqueiro","doi":"10.1016/j.ecoenv.2025.117750","DOIUrl":"https://doi.org/10.1016/j.ecoenv.2025.117750","url":null,"abstract":"<p><p>Seeds of four native species of trees and shrubs (Larrea cuneifolia, Bulnesia retama, Plectrocarpa tetracantha and Prosopis flexuosa) were exposed to soil contaminated with As, Cu, Cd, and Zn from an abandoned gold mine to identify adaptation strategies. Several physiological, morpho-anatomical, and biochemical parameters were determined. The seed germination of L. cuneifolia, B. retama, and P. tetracantha was fully inhibited in 100 % contaminated soil. Toxicological endpoints as NOEC, LOEC and IC50 ranged from 10 % to 25 % of soil contaminated with mining waste. Radicle elongation was the most sensitive variable to high metal(loid) concentrations, except for L. cuneifolia that hypocotyl elongation was the most affected parameter. P. flexuosa was selected to evaluate biochemical biomarkers and morpho-anatomical parameters. It showed an increase in radicle diameter and central radicle cylinder. A concentration-dependent increase in the O₂^·- production was observed in radicle and cotyledon. A peak of the enzymatic activity of guaiacol peroxidase, ascorbate peroxidase and catalase enzymes in P. flexuosa seedlings showed a negative relationship between metal(loid) concentration and exposure time. After a drop in the enzymatic activity, an increase in the malondialdehyde content (lipid peroxidation) was observed. The tested native species could be useful for phytoremediation of soils with a very high degree of metal contamination. A further investigation should focus on strategies to improve soil physicochemical characteristics for plant survival at highest contamination levels.</p>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"290 ","pages":"117750"},"PeriodicalIF":6.2,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomonitoring potential of trace metal accumulation and bioavailability in coral skeletons and reef sediments of Persian Gulf: A comparative study.","authors":"Seyed Hassan Mousavi, Mehdi Gholamalifard, Seyed Mahmoud Ghasempouri","doi":"10.1016/j.ecoenv.2025.117786","DOIUrl":"https://doi.org/10.1016/j.ecoenv.2025.117786","url":null,"abstract":"<p><p>Nayband Marine National Park in the northern Persian Gulf is an important ecological areas, significantly impacted by industrial activites that poses risk of trace metal pollution to living organisms. In this study, we investigated the bioaccumulation of trace metals in scleractinian corals using annual growth bands and biota-sediment accumulation factor to assess their potential as biomonitoring organisms. Furthermore, to assess the sediment quality, sediment pollution indices and international guidelines was employed. To achieve this, three Faviidae coral and sixteen sediment samples were collected in March 2023 from three sites: an industrial zone (site I), a rural fishing zone (site II), and a marine protected area (site III). In first step, coral samples washed, sun-dried, sliced into 1-cm slabs, X-rayed to reveal annual growth bands, and powder was prepared from each growth band. Then freeze-dried sediments and coral powder were ground, sieved (63 μm), digested (using United States Environmental Protection Agency - Method 3050b) and filtered (Whatman No. 42). Finally, trace metals were analyzed using Inductively Coupled Plasma Mass Spectrometry instrument. The results show severe anthropogenic pollution at sites I and II compared to site III and significant differences between their sampling stations. Mg and Sr concentrations were highest in sediments and corals, respectively, while, Co is lowest in both. According to the sediment pollution indices, Site I showed the highest potential toxicity to biota, followed by Site II and then Site III. The results also suggest that the Faviidae corals are effective bio-indicators for Pb, Li, Cu, and Ni contamination.</p>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"290 ","pages":"117786"},"PeriodicalIF":6.2,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations and potential epigenetic changes between air pollution and osteoarthritis risk and survival: Insights from a prospective cohort study.","authors":"Jing Qian, Jiahao Zhu, Yifan Wang, Ruoqi Dai, Jingyou Miao, Ye Yang, Wenxia Zhao, Jing Wang, Lilu Ding, Dan Zhou, Min Yu, Yingjun Li","doi":"10.1016/j.ecoenv.2025.117770","DOIUrl":"https://doi.org/10.1016/j.ecoenv.2025.117770","url":null,"abstract":"<p><strong>Background: </strong>The influence of air pollution on osteoarthritis (OA) remains underexplored.</p><p><strong>Methods: </strong>We conducted a prospective cohort study in the UK Biobank, estimating exposure levels of particulate matter (PM_2.5, PM₁₀, PM_2.5-10)^, nitrogen oxides (NO₂, NO_x), and air pollutants exposure score (APES). Cox models assessed associations between air pollution exposure and OA incidence, joint replacement, and survival. Additionally, using genome-wide association statistics, we examined the potential causal associations between air pollution-related DNA methylation (DNAm) and OA risk. Gene-environment interaction analyses were conducted to explore the potential modification effect of DNA methylation-related genetic variants on the impact of air pollution on OA risk.</p><p><strong>Results: </strong>Individual exposure to each air pollutant was associated with an increased risk of developing OA, but not with progression from OA to joint replacement. For APES, the hazard ratio for incident OA was 1.09 (95 % CI = 1.04-1.13), and the hazard ratio of progression from OA to death was 1.16 (95 % CI = 1.00-1.35) in the highest quartile group compared to the lowest quartile group. Moreover, genetically predicted methylation at the PM_2.5-related CpG site cg04027612 near the GDF5 gene was associated with a lower risk of OA. A potential epigenetic modification effect of cg04027612 near GDF5 on OA risk was observed.</p><p><strong>Conclusion: </strong>Long-term exposure to air pollution was associated with an increased risk of OA in the population and poorer survival outcomes for OA patients, with epigenetic changes in GDF5 potentially playing a role in the underlying mechanisms.</p>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"290 ","pages":"117770"},"PeriodicalIF":6.2,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between brominated flame retardants exposure and non-alcoholic fatty liver disease: Mediation analysis in the NHANES.","authors":"Yulan Cheng, Jingyi Su, Xiangdong Wang, Ruiyao Huang, Zixuan Zhao, Kai Tian, Tianxiang Gu, Xiaoke Wang, Lin Chen, Xinyuan Zhao","doi":"10.1016/j.ecoenv.2025.117762","DOIUrl":"https://doi.org/10.1016/j.ecoenv.2025.117762","url":null,"abstract":"<p><strong>Background: </strong>Exposure to brominated flame retardants (BFRs) may negatively impact human health. The association of BFRs with nonalcoholic fatty liver disease (NAFLD) in the general population is unclear. Meanwhile, limited studies have investigated the potential role of oxidative stress and inflammation in this link.</p><p><strong>Methods: </strong>We included 4110 adults from the 2009-2014 National Health and Nutrition Examination Survey (NHANES). NAFLD was diagnosed by serum alanine aminotransferase (ALT), hepatic steatosis index (HSI), and United States fatty liver index (USFLI). The link between a single BFR exposure and NAFLD was estimated using weighted logistic regression and restricted cubic splines (RCS). The quantile-based g-computation (QGC), weighted quantile sum (WQS) regression, and Bayesian kernel machine regression (BKMR) were applied to evaluate the overall correlation of BFRs mixtures with NAFLD and identify significant compounds. Furthermore, we investigated the potential mediation function of oxidative stress and inflammation.</p><p><strong>Results: </strong>Our study demonstrated that specific concentrations of BFRs are related to an increased risk of NAFLD, both individually and when combined. PBB153, PBDE28, PBDE209, and PBDE153 exhibited the highest importance for NAFLD and were potential risk factors worthy of concern. Additionally, mediation analysis showed that absolute neutrophil cell count (ANC) and lymphocyte count (LC) (inflammation markers) have significantly mediated influences on the correlations of PBB153, PBDE85, and PBDE28 with N AFLD risk. Albumin (ALB) (oxidative stress marker) has notably mediated influences on the correlations of PBDE99, PBDE154, and PBDE85 with NAFLD risk. Men had higher serum BFRs concentrations than women, and the association between BFRs and NAFLD was also more prominent in men, which may be related to physiological differences between the sexes.</p><p><strong>Conclusions: </strong>Our findings offer evidence for single and mixed associations of BFRs and NAFLD in ordinary US adults. Furthermore, oxidative stress and chronic inflammation may mediate the effects of BFR exposure on NAFLD development.</p>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"290 ","pages":"117762"},"PeriodicalIF":6.2,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the distribution and fate of bisphenol A in an aquatic microcosm combined with a multimedia model.","authors":"Dan Liu, Guodong Kang, Yixi Zhang, Lili Shi, Bo Ma, Shenghu Zhang, Guojian Lu","doi":"10.1016/j.ecoenv.2025.117752","DOIUrl":"https://doi.org/10.1016/j.ecoenv.2025.117752","url":null,"abstract":"<p><p>Bisphenol A (BPA), a well-known endocrine-disrupting chemical, has garnered significant attention in environmental science and policy. BPA can enter the aquatic environment through different routes, posing potential risks even at a low concentration. In this study, a four-compartment system [water, sediment, biota (zebrafish), and submerged aquatic vegetation (Vallisneria natans)] of a point source continuous discharge microcosm was established to investigate the distribution and fate of BPA in an aquatic microcosm. The fugacity model generated predicted values were highly consistent with those of the experiments. The distribution of BPA in the model indicates that sediment was the dominant sink. The residence time of reaction and advection was 5.8 and 75.2 d, respectively, which showed that BPA was mainly removed from the aquatic microcosm through the reaction in biota (58 %). Sensitivity analysis revealed that emission data were the most influential parameters for the model output. Transfer processes between the water and biota phases had a closer relationship. This study provides technical support for pollution source management and risk assessment for BPA.</p>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"290 ","pages":"117752"},"PeriodicalIF":6.2,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143021373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variations of microbiota and metabolites in rhizosphere soil of Carmona microphylla at the co-contaminated site with polycyclic aromatic hydrocarbons and heavy metals.","authors":"Ying Zhang, Fanghan Qian, Yanyu Bao","doi":"10.1016/j.ecoenv.2025.117734","DOIUrl":"https://doi.org/10.1016/j.ecoenv.2025.117734","url":null,"abstract":"<p><p>Co-contamination with organic/inorganic compounds is common in industrial area and poses a great risk to local soil ecological environment. In this study, an operating ink factory site co-contaminated with polycyclic aromatic hydrocarbons (PAHs, mild to moderate pollution level) and heavy metals (HMs, heavy pollution level) was selected and screened for native vegetation, Carmona microphylla. High-throughput sequencing and metabolomics were mainly used to investigate the responses of soil bacteria and metabolites to the composite pollution and rhizosphere effect. As the results showed, among three pollution levels, a medium level of pollution was favorable to increase the richness and diversity of soil bacterial community, while high level of pollution greatly decreased special OTUs number. In addition, HMs were the most significant factors driving bacterial community structure, especially for Cd. The influence of medium molecular weight PAHs with 4 rings (MMW-PAHs) on dominant bacteria was greater than low molecular weight PAHs with 2-3 rings (LMW-PAHs) and high molecular weight PAHs with 5-6 rings (HMW-PAHs). Soil bacterial function was affected mainly by pollution level, but not rhizosphere effect, in which high pollution level changed α diversity and structure and composition of C- and N-cycling bacteria. Rhizosphere promoted network complexity by increasing the connection densities among bacterial communities, metabolites, soil properties and the involved number of metabolites. Compared to HMs, PAHs played a more important role in shaping bacterial community through affecting metabolites in non-rhizosphere soil, which was different from rhizosphere soil with a more significant effect of HMs than PAHs. Some key bacterial taxa have established resistance to HMs in rhizosphere soils, whereas they were sensitive to compound contamination in non-rhizosphere soils. Some key bacterial taxa are resistant to HMs in rhizosphere soils, whereas they are susceptible to complex contamination in non-rhizosphere soils, which could be a consequence of the rhizosphere by regulating soil metabolism. It also provides a valuable reference for how co-contaminants and rhizosphere effect shape together soil bacterial community through the changes of soil metabolites.</p>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"290 ","pages":"117734"},"PeriodicalIF":6.2,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143021425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Removal of Di (2-ethylhexyl) phthalate from groundwater by sodium persulfate activated by hollow micron zero-valent iron: Reaction mechanism and degradation path.","authors":"Chunyang Gao, Bing Wang, Jingjing Zhao, Jvfeng Li, Xianyuan Du, Jin Zheng, Quanwei Song, Jiacai Xie","doi":"10.1016/j.ecoenv.2025.117720","DOIUrl":"https://doi.org/10.1016/j.ecoenv.2025.117720","url":null,"abstract":"<p><p>In this study, hollow micron zero-valent iron (H-mZVI) was prepared using the ethylenediamine liquid phase reduction method. The microstructures were characterized by SEM, XRD, BET and FTIR. The results showed that H-mZVI possessed a spherical hollow structure with a particle size of approximately 1 μm. The density of H-mZVI was notably lower compared to solid micron zero-valent iron (S-mZVI). Furthermore, with an increase in ethylenediamine addition, the density initially decreased before stabilizing. Results demonstrated that the degradation efficiency of H-mZVI/PS for DEHP was 2.96 times higher than that of S-mZVI/PS. The charge density of H-mZVI/PS degradation DEHP system was higher than that of S-mZVI/PS system, and H-mZVI exhibited a fast electron migration rate and strong electron transport ability between the solution and the interface material. The degradation of DEHP by H-mZVI/PS system was carried out jointly by the surface reaction on the surface of H-mZVI particles and the homolytic reaction led by Fe²⁺ ions in the solution. Additionally, the contribution rate of free radicals in the degradation process of DEHP was in the order SO₄^-· > ·OH > ¹O₂. There were three degradation pathways of DEHP in H-mZVI/PS system, and the toxicity of DEHP degradation products was significantly lower than that of the parent.</p>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"290 ","pages":"117720"},"PeriodicalIF":6.2,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143021399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}