ACS Measurement Science Au最新文献

{"title":"Rapid Detection of Nanoplastic Contamination in Plastic Labware by Dynamic Light Scattering Highlights Variations in Experimental Precision.","authors":"Wei Wei, Song Lin Chua","doi":"10.1021/acsmeasuresciau.5c00142","DOIUrl":"https://doi.org/10.1021/acsmeasuresciau.5c00142","url":null,"abstract":"<p><p>Nanoplastics (NPs) are emerging contaminants of environmental concern, raising significant alarms due to their prevalence and potential health risks. Unlike larger microplastics, NPs are challenging to detect due to their nanodimensions and the reliance on labor-intensive methods such as nanoparticle tracking analysis (NTA) or scanning electron microscopy (SEM). This underscores the urgent need for rapid and accessible detection methods. To address these challenges, we employed dynamic light scattering (DLS), a widely used technique for measuring nanoparticle sizes, to rapidly quantify NP concentrations and sizes. Using DLS, we demonstrated the prevalence of NPs originating from laboratory-based plastic consumables such as microcentrifuge tubes, cryovials, and Petri dishes. Notably, routine actions, including pipet-tip scraping against plastic labware during sample handling, can introduce NPs into solutions. Moreover, physical or chemical procedures, especially sonication and liquid nitrogen treatment, further exacerbate the NP release. This interfered with experimental outcomes, including skewing of DNA and iron nanoparticle concentrations. Our material analysis revealed that the NPs were made of polystyrene and polypropylene, which correlated to manufacturers' product details. Hence, our study highlights an under-recognized NP source that compromises research integrity while contributing to global NP pollution, thus emphasizing the need for sustainable laboratory practices and robust contamination control.</p>","PeriodicalId":29800,"journal":{"name":"ACS Measurement Science Au","volume":"6 1","pages":"126-133"},"PeriodicalIF":4.6,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12921585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147272257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wireless IrO _<b>2</b> Electrochemical Sensor System for Real-Time pH Monitoring in Microliter Volumes.","authors":"Sekar Madhu, Sriramprabha Ramasamy, Jungil Choi","doi":"10.1021/acsmeasuresciau.5c00181","DOIUrl":"https://doi.org/10.1021/acsmeasuresciau.5c00181","url":null,"abstract":"<p><p>Accurate pH measurement in microliter volumes is essential for real-time chemical and biological analysis, underpinning modern portable and point-of-care diagnostics. Here, we present a wireless electrochemical pH sensor system based on nanostructured iridium oxide (IrO₂) electrodeposited onto electron-beam-evaporated, photolithographically patterned gold electrodes (EBLG) and integrated with a low-power Bluetooth potentiostat for continuous, real-time pH monitoring. FESEM, Raman, and XPS confirm uniform spherical IrO₂ nanostructures with mixed Ir³⁺/Ir⁴⁺ states that are conducive to potentiometric transduction. The IrO₂/EBLG sensor exhibited near-Nernstian sensitivity (69.7 mV/pH) across a pH range of 2-9, a fast step response (∼10 s), negligible hysteresis during bidirectional cycling, and exceptionally low potential drift (∼0.12-0.28 mV/h over 12 h). It demonstrates high selectivity toward H⁺ ions against common physiological interferences with excellent reproducibility and robust long-term stability. The hand-held module wirelessly streams real-time potential data to a smartphone, enabling accurate pH quantification in microliter-scale biological, food, and environmental samples. Measurements showed strong agreement with a commercial microelectrode pH meter, with no statistically significant difference (<i>p</i> > 0.05; Bland-Altman and paired <i>t</i>-test). Overall, the IrO₂/EBLG platform combines miniaturization, stability, and wireless functionality, offering a reliable and scalable solution for decentralized pH sensing and paving a promising route toward future wearable, field-deployable, and environmental pH monitoring systems.</p>","PeriodicalId":29800,"journal":{"name":"ACS Measurement Science Au","volume":"6 1","pages":"238-248"},"PeriodicalIF":4.6,"publicationDate":"2026-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12921622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147272067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flexible Electrochemical Biosensor for Non-Invasive, on-Site Cortisol Monitoring in Sweat and Saliva.","authors":"Sonal Fande, Dharmarajan Sriram, Sanket Goel","doi":"10.1021/acsmeasuresciau.5c00153","DOIUrl":"https://doi.org/10.1021/acsmeasuresciau.5c00153","url":null,"abstract":"<p><p>Chronic stress is a critical public health concern with strong links to both mental and physical health. Excessive stress alters brain architecture and stimulates the adrenal gland to release cortisol, a key biomarker of stress. Conventional cortisol measurements rely on invasive, laboratory-based methods that are unsuitable for real-time, point-of-care testing. This study reports the development of a noninvasive, flexible electrochemical biosensor for the selective detection of cortisol in human sweat and saliva. The sensor was fabricated on a polyethylene terephthalate (PET) substrate coated with indium tin oxide (ITO) and functionalized with gold nanoparticles (AuNPs) to enhance conductivity and surface area. AnteoBind chemistry was employed for oriented immobilization of monoclonal anticortisol antibodies. The device was integrated with a microfluidic platform to enable controlled sweat analysis. Electrochemical measurements demonstrated a linear response over the range of 0.5-150 ng/mL, with a detection limit of 0.58 ng/mL. The sensor retained 80% of its signal over 30 days, with reproducibility across batches (RSD ∼ 3.2%). Real sample analysis showed recovery values of 95.5-104% in sweat and saliva samples. These findings underscore the potential of this biosensor for noninvasive monitoring of stress markers in wearable applications, supporting early stress detection and personalized health management.</p>","PeriodicalId":29800,"journal":{"name":"ACS Measurement Science Au","volume":"6 1","pages":"170-178"},"PeriodicalIF":4.6,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12921587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147272230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harnessing New Tools for Old Challenges: Optimising Neat Plasma Proteomics with Automation and Gas-Phase Fractionation.","authors":"Colleen B Maxwell, Dan Lane, Nikita Bhakta, Emer M Brady, Richard D Haigh, Rajinder Singh, Gaurav S Gulsin, Gerry P McCann, Leong L Ng, Donald J L Jones","doi":"10.1021/acsmeasuresciau.5c00166","DOIUrl":"https://doi.org/10.1021/acsmeasuresciau.5c00166","url":null,"abstract":"<p><p>Advances in high-throughput mass spectrometry have shifted the bottleneck in plasma proteomics from data acquisition to sample preparation. While enrichment and depletion strategies enable detection of low-abundance proteins, their complexity and cost limit scalability and clinical translation. Targeting midto-high abundance proteins from neat plasma offers a practical, reproducible alternative aligned with clinical workflows. Here, we combine fully automated sample preparation and Evotip loading on the Bravo AssayMAP system with extensive method optimization on the timsTOF HT and gas-phase fractionation deep spectral libraries to advance neat plasma proteomics. Automation reduced hands-on time by 88% and significantly improved robustness. Mixed-mode searching with a 1788-protein library increased identifications by up to 31% at a throughput of 100 samples per day, with less than 15% variation across plates. In a coronary artery disease cohort, we quantified 936 biologically relevant proteins and found 42 dysregulated compared to healthy controls. This streamlined, high-throughput workflow enables deep, reproducible analysis of neat plasma at scale, paving the way for population-level biomarker discovery and clinical implementation.</p>","PeriodicalId":29800,"journal":{"name":"ACS Measurement Science Au","volume":"6 1","pages":"224-237"},"PeriodicalIF":4.6,"publicationDate":"2026-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12921592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147272194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transmission Electron Microscopy for Structural Insights into Bacterial Cellulose Nanowhiskers in Ternary Deep Eutectic Solvent.","authors":"Maurelio Cabo, Abed Alqader Ibrahim, Gayani Pathiraja, Farbod Ebrahimi, Shobha Mantripragada, Omiya Ayoub, Besan Khader, Kristen Dellinger, Jeffrey R Alston, Sherine O Obare, Dennis R LaJeunesse","doi":"10.1021/acsmeasuresciau.5c00159","DOIUrl":"https://doi.org/10.1021/acsmeasuresciau.5c00159","url":null,"abstract":"<p><p>In this study, we used Transmission Electron Microscopy (TEM) to establish that bacterial cellulose formed nanowhisker (BCWN) rod-like structures with distinct short and long morphologies when fabricated in a ternary deep eutectic solvent (TDES) of choline chloride, imidazole, and tannic acid. STEM-EDS confirmed nanowhisker twisting, diameter, elongation, and elemental composition. BCNWs enhanced TDES thermal stability by increasing the decomposition temperature and residual yield. DLS and zeta potential showed particle size enlargement and charge reversal, while DSC indicated a reduced melting temperature and restricted molecular mobility. Thus, TEM not only elucidated cellulose morphology but also provided insights into structural transformations and the reinforcing role of BCNWs in tuning eutectic solvent properties for sustainable nanomaterials and potential polymer electrolyte applications.</p>","PeriodicalId":29800,"journal":{"name":"ACS Measurement Science Au","volume":"6 1","pages":"28-34"},"PeriodicalIF":4.6,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12921604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147272106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual Ionization Ion-Mobility Mass Spectrometry Hyphenated with Catalytic Oxygenation-Mediated Extraction.","authors":"Tzu-Ching Tsai, Chamarthi Maheswar Raju, Pawel L Urban","doi":"10.1021/acsmeasuresciau.5c00160","DOIUrl":"https://doi.org/10.1021/acsmeasuresciau.5c00160","url":null,"abstract":"<p><p>Catalytic oxygenation-mediated extraction (COME) is an environmentally friendly liquid-gas extraction technique that generates oxygen microbubbles via the catalytic decomposition of hydrogen peroxide. While corona discharge atmospheric pressure chemical ionization (APCI) is widely used for analyzing moderately polar and lower-polarity analytes with low molecular weights, secondary electrospray ionization (SESI) is a soft ionization technique that effectively ionizes polar volatile analytes. This study aims to integrate APCI and SESI with COME drift-tube ion-mobility (IM) triple quadrupole mass spectrometry (MS) to analyze volatile organic compounds (VOCs) with different physicochemical properties present in liquid matrices. The coupling of a house-built ion-mobility spectrometer with a commercial triple quadrupole mass spectrometer provides 2D separation at low cost. The user can choose one of the two ionization modes to achieve high signals with VOCs of different polarity. COME was applied to extract ethyl acetate from complex matrices (Taiwanese millet wine and whiskey) for immediate IM-MS analysis. An isotopically labeled internal standard was used to compensate for drift time and intensity shifts across multiple analyses. The system operates automatically with a graphical user interface enabling immediate ion-mobility spectrum visualization for targeted <i>m</i>/<i>z</i>.</p>","PeriodicalId":29800,"journal":{"name":"ACS Measurement Science Au","volume":"6 1","pages":"204-213"},"PeriodicalIF":4.6,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12921609/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147272161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pyrolyzed Parylene Electrodes for Detection of Tryptophan, Tyrosine, and Gonadotropin-Releasing Hormone.","authors":"Faith Eyimegwu, He Zhao, Kailash Shrestha, Dayana Surendran, Nickolay V Lavrik, B Jill Venton","doi":"10.1021/acsmeasuresciau.5c00165","DOIUrl":"https://doi.org/10.1021/acsmeasuresciau.5c00165","url":null,"abstract":"<p><p>Sensitive and selective detection of neurochemicals such as neuropeptides is critical for understanding brain signaling. While carbon-fiber microelectrodes (CFMEs) are widely used for these measurements, alternative electrode materials and fabrication techniques could improve sensitivity and versatility. In this study, we investigate pyrolyzed parylene-N microelectrodes (PPNMEs) as a promising platform for making thin-film carbon electrodes for the detection of electroactive amino acids and neuropeptides. We evaluated the performance of PPNMEs for the detection of tryptophan (Trp), tyrosine (Tyr), and the neuropeptide gonadotropin-releasing hormone (GnRH), which contains these electroactive residues. PPNMEs demonstrated significantly greater sensitivity with fast-scan cyclic voltammetry, with signal amplitudes approximately four times higher than those observed with CFMEs. After normalization for surface area, PPNMEs exhibited 3-, 5-, and 2.7-fold higher signals than CFMEs for Trp, Tyr, and GnRH, respectively. Additionally, PPNMEs facilitated faster electron transfer kinetics, as evidenced by reduced oxidation potentials. There were enhanced signals for secondary oxidation peaks at PPNMEs because the rougher surface can trap intermediates near the surface, facilitating detection of downstream electrochemical reactions. Scan rate analysis indicates more adsorption-controlled detection, contributing to improved sensitivity. Importantly, PPNMEs enabled sensitive detection of GnRH in brain tissue slices, including both puffed-on applications and spontaneous endogenous GnRH release in the median eminence. These results highlight the potential of PPNMEs as a new class of carbon-based electrodes, offering a promising alternative to CFMEs for high-sensitivity, low-potential detection of neurochemicals in biological tissues.</p>","PeriodicalId":29800,"journal":{"name":"ACS Measurement Science Au","volume":"6 1","pages":"214-223"},"PeriodicalIF":4.6,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12921596/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147272222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systematically Enhanced LAMP Chip for Rapid, Sensitive, and Contamination-Free Pathogen Detection.","authors":"Sajid Uchayash, Jinping Zhao, Md Iqbal Kabir, Junqi Song, Long Que","doi":"10.1021/acsmeasuresciau.5c00155","DOIUrl":"https://doi.org/10.1021/acsmeasuresciau.5c00155","url":null,"abstract":"<p><p>Main techniques for pathogen detection include molecular or nucleic acid-based methods, such as polymerase chain reaction (PCR) and loop-mediated isothermal amplification (LAMP). Among these, chip-based LAMP provides a particularly promising platform for point-of-care diagnostics. To ensure accurate, reliable, and robust pathogen detection, systematic optimization of the LAMP-chip system is essential. Building on our previously developed LAMP-chip platform, we report a systematically advanced version for the rapid and sensitive detection of <i>Phytophthora infestans</i>. By systematically investigating the effects of primer concentrations, immobilization ratios, and reaction conditions, we identified an optimal configuration involving immobilized forward inner primers (FIP) on the sensor surface and unmodified backward inner primers (BIP) in solution. This approach enabled the detection of <i>P. infestans</i> DNA at concentrations as low as 1 fg/μL, with a transducing optical signal shift of up to 4.33 nm after a 30 min reaction. Further refinement reduced detection time to under 20 min, a 33% reduction of conventional LAMP detection time, without compromising sensitivity. Notably, the use of EDC-NHS chemistry for primer immobilization on the anodic aluminum oxide (AAO) nanopore surface of the LAMP chip effectively minimizes carryover contamination by strictly confining amplification to the chip, representing a major advance over conventional LAMP approaches. This robust, label-free, and user-friendly system offers a promising solution for point-of-care plant pathogen diagnostics, enabling accurate and rapid field-based detection to support timely disease management and improve agricultural outcomes.</p>","PeriodicalId":29800,"journal":{"name":"ACS Measurement Science Au","volume":"6 1","pages":"179-188"},"PeriodicalIF":4.6,"publicationDate":"2025-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12921607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147272179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Si₃N₄ Microring Resonator-Based Refractive Index Sensing for Liquid Samples: Comparing Wavelength Scanning and Fixed-Wavelength Probing.","authors":"Daniela Tomasetig, Jesus Hernan Mendoza-Castro, Silvia Schobesberger, Artem S Vorobev, Liam O'Faolain, Bernhard Lendl","doi":"10.1021/acsmeasuresciau.5c00139","DOIUrl":"https://doi.org/10.1021/acsmeasuresciau.5c00139","url":null,"abstract":"<p><p>Measuring refractive index (RI) changes of liquid samples is central to many sensing applications including flow injection analysis, liquid chromatography, biosensing and photothermal spectroscopy. Commercial refractive index detectors optimized for liquid chromatography suffer from a limited linear range and measurement rate, restricting their use largely to separation sciences. In contrast, microring resonators (MRR) integrated with low-volume microfluidics, offer enhanced performance by minimizing sample dilution during flow-through RI measurements and increased dynamic range. MRRs realized by modern photonic integrated circuitry (PIC) technology also have the potential to be used as transducers in more advanced sensing schemes. Here, we demonstrate a silicon nitride (Si₃N₄) MRR integrated into a low-volume microfluidic system as a compact, chip-scale RI detector capable of real-time operation under dynamic flow conditions. Two interrogation modalities were experimentally compared for flow-through liquid sensing using the same MRR for the first time: resonance wavelength scanning for wide-range refractive index detection, and fixed-wavelength probing on the resonance slope for high-speed measurements. Using glucose solutions as test samples, the device was benchmarked against a commercial RI detector, achieving a sensitivity of 113 nm/RIU and a sLOD of 2.3 × 10^-6 RIU (0.014 g/L glucose). To demonstrate the applicability of the developed RI-sensor for resolving transient RI peaks in realistic chromatographic flow conditions we also report its successful use in an isocratic separation of four sugars (sorbitol, fructose, glucose, and sucrose). These results highlight the potential of integrated Si₃N₄ MRRs as versatile, miniaturized transducers for quantitative, high-speed RI sensing in flow-based analytical systems.</p>","PeriodicalId":29800,"journal":{"name":"ACS Measurement Science Au","volume":"6 1","pages":"116-125"},"PeriodicalIF":4.6,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12921590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147272024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemically Resolved Nuclear Magnetic Resonance Spectroscopy by Longitudinal Magnetization Detection with a Diamond Magnetometer.","authors":"Janis Smits, Yaser Silani, Zaili Peng, Bryan A Richards, Andrew F McDowell, Joshua T Damron, Maxwell D Aiello, Maziar Saleh Ziabari, Andrey Jarmola, Victor M Acosta","doi":"10.1021/acsmeasuresciau.5c00134","DOIUrl":"https://doi.org/10.1021/acsmeasuresciau.5c00134","url":null,"abstract":"<p><p>Noninductive magnetometers based on nitrogen-vacancy centers in diamond offer a promising solution for small-volume nuclear magnetic resonance (NMR) detection. A remaining challenge is to operate at a sufficiently high magnetic field to resolve chemical shifts at the part-per-billion level. Here, we demonstrate a Ramsey-<i>M</i> _<i>z</i> protocol that uses Ramsey interferometry to convert an analyte's transverse spin precession into a longitudinal magnetization (<i>M</i> _<i>z</i> ), which is subsequently modulated and detected with a diamond magnetometer. We recorded NMR spectra at <i>B</i> ₀ = 0.32 T with a fractional spectral resolution of ∼350 ppb, limited by the stability of the electromagnet bias field. We resolve the chemical shift structure of ethanol with negligible distortion. Based on the laser illumination volume within the diamond (∼0.9 nL), we calculate an effective analyte detection volume of ∼1 nL. Through simulation, we show that the protocol can be extended to fields up to <i>B</i> ₀ = 3 T, with minimal spectral distortion, by using composite nuclear-spin inversion pulses. For subnanoliter analyte volumes, we estimate a resolution of ∼1 ppb and a concentration sensitivity of ∼40 mM s^1/2 are feasible with improvements to the sensor design. Our results establish diamond magnetometers as high-resolution NMR detectors in the moderate magnetic field regime, with potential applications in metabolomics and pharmaceutical research.</p>","PeriodicalId":29800,"journal":{"name":"ACS Measurement Science Au","volume":"6 1","pages":"107-115"},"PeriodicalIF":4.6,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12921615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147272232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}