Radiology-Artificial Intelligence最新文献

{"title":"Bridging Pixels to Genes.","authors":"Mana Moassefi, Bradley J Erickson","doi":"10.1148/ryai.240262","DOIUrl":"10.1148/ryai.240262","url":null,"abstract":"","PeriodicalId":29787,"journal":{"name":"Radiology-Artificial Intelligence","volume":"6 4","pages":"e240262"},"PeriodicalIF":8.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11294947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141427771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical, Cultural, Computational, and Regulatory Considerations to Deploy AI in Radiology: Perspectives of RSNA and MICCAI Experts.","authors":"Marius George Linguraru, Spyridon Bakas, Mariam Aboian, Peter D Chang, Adam E Flanders, Jayashree Kalpathy-Cramer, Felipe C Kitamura, Matthew P Lungren, John Mongan, Luciano M Prevedello, Ronald M Summers, Carol C Wu, Maruf Adewole, Charles E Kahn","doi":"10.1148/ryai.240225","DOIUrl":"10.1148/ryai.240225","url":null,"abstract":"<p><p>The Radiological Society of North of America (RSNA) and the Medical Image Computing and Computer Assisted Intervention (MICCAI) Society have led a series of joint panels and seminars focused on the present impact and future directions of artificial intelligence (AI) in radiology. These conversations have collected viewpoints from multidisciplinary experts in radiology, medical imaging, and machine learning on the current clinical penetration of AI technology in radiology and how it is impacted by trust, reproducibility, explainability, and accountability. The collective points-both practical and philosophical-define the cultural changes for radiologists and AI scientists working together and describe the challenges ahead for AI technologies to meet broad approval. This article presents the perspectives of experts from MICCAI and RSNA on the clinical, cultural, computational, and regulatory considerations-coupled with recommended reading materials-essential to adopt AI technology successfully in radiology and, more generally, in clinical practice. The report emphasizes the importance of collaboration to improve clinical deployment, highlights the need to integrate clinical and medical imaging data, and introduces strategies to ensure smooth and incentivized integration. <b>Keywords:</b> Adults and Pediatrics, Computer Applications-General (Informatics), Diagnosis, Prognosis © RSNA, 2024.</p>","PeriodicalId":29787,"journal":{"name":"Radiology-Artificial Intelligence","volume":" ","pages":"e240225"},"PeriodicalIF":8.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11294958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141564666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of an Artificial Intelligence System for Breast Cancer Detection on Screening Mammograms from BreastScreen Norway.","authors":"Marthe Larsen, Camilla F Olstad, Christoph I Lee, Tone Hovda, Solveig R Hoff, Marit A Martiniussen, Karl Øyvind Mikalsen, Håkon Lund-Hanssen, Helene S Solli, Marko Silberhorn, Åse Ø Sulheim, Steinar Auensen, Jan F Nygård, Solveig Hofvind","doi":"10.1148/ryai.230375","DOIUrl":"10.1148/ryai.230375","url":null,"abstract":"<p><p>Purpose To explore the stand-alone breast cancer detection performance, at different risk score thresholds, of a commercially available artificial intelligence (AI) system. Materials and Methods This retrospective study included information from 661 695 digital mammographic examinations performed among 242 629 female individuals screened as a part of BreastScreen Norway, 2004-2018. The study sample included 3807 screen-detected cancers and 1110 interval breast cancers. A continuous examination-level risk score by the AI system was used to measure performance as the area under the receiver operating characteristic curve (AUC) with 95% CIs and cancer detection at different AI risk score thresholds. Results The AUC of the AI system was 0.93 (95% CI: 0.92, 0.93) for screen-detected cancers and interval breast cancers combined and 0.97 (95% CI: 0.97, 0.97) for screen-detected cancers. In a setting where 10% of the examinations with the highest AI risk scores were defined as positive and 90% with the lowest scores as negative, 92.0% (3502 of 3807) of the screen-detected cancers and 44.6% (495 of 1110) of the interval breast cancers were identified with AI. In this scenario, 68.5% (10 987 of 16 040) of false-positive screening results (negative recall assessment) were considered negative by AI. When 50% was used as the cutoff, 99.3% (3781 of 3807) of the screen-detected cancers and 85.2% (946 of 1110) of the interval breast cancers were identified as positive by AI, whereas 17.0% (2725 of 16 040) of the false-positive results were considered negative. Conclusion The AI system showed high performance in detecting breast cancers within 2 years of screening mammography and a potential for use to triage low-risk mammograms to reduce radiologist workload. <b>Keywords:</b> Mammography, Breast, Screening, Convolutional Neural Network (CNN), Deep Learning Algorithms <i>Supplemental material is available for this article</i>. © RSNA, 2024 See also commentary by Bahl and Do in this issue.</p>","PeriodicalId":29787,"journal":{"name":"Radiology-Artificial Intelligence","volume":" ","pages":"e230375"},"PeriodicalIF":9.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140862082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficient Health Care: Decreasing MRI Scan Time.","authors":"Farid GharehMohammadi, Ronnie A Sebro","doi":"10.1148/ryai.240174","DOIUrl":"10.1148/ryai.240174","url":null,"abstract":"","PeriodicalId":29787,"journal":{"name":"Radiology-Artificial Intelligence","volume":"6 3","pages":"e240174"},"PeriodicalIF":9.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140865263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Semi-supervised Learning for Generalizable Intracranial Hemorrhage Detection and Segmentation.","authors":"Emily Lin, Esther L Yuh","doi":"10.1148/ryai.230077","DOIUrl":"10.1148/ryai.230077","url":null,"abstract":"<p><p>Purpose To develop and evaluate a semi-supervised learning model for intracranial hemorrhage detection and segmentation on an out-of-distribution head CT evaluation set. Materials and Methods This retrospective study used semi-supervised learning to bootstrap performance. An initial \"teacher\" deep learning model was trained on 457 pixel-labeled head CT scans collected from one U.S. institution from 2010 to 2017 and used to generate pseudo labels on a separate unlabeled corpus of 25 000 examinations from the Radiological Society of North America and American Society of Neuroradiology. A second \"student\" model was trained on this combined pixel- and pseudo-labeled dataset. Hyperparameter tuning was performed on a validation set of 93 scans. Testing for both classification (<i>n</i> = 481 examinations) and segmentation (<i>n</i> = 23 examinations, or 529 images) was performed on CQ500, a dataset of 481 scans performed in India, to evaluate out-of-distribution generalizability. The semi-supervised model was compared with a baseline model trained on only labeled data using area under the receiver operating characteristic curve, Dice similarity coefficient, and average precision metrics. Results The semi-supervised model achieved a statistically significant higher examination area under the receiver operating characteristic curve on CQ500 compared with the baseline (0.939 [95% CI: 0.938, 0.940] vs 0.907 [95% CI: 0.906, 0.908]; <i>P</i> = .009). It also achieved a higher Dice similarity coefficient (0.829 [95% CI: 0.825, 0.833] vs 0.809 [95% CI: 0.803, 0.812]; <i>P</i> = .012) and pixel average precision (0.848 [95% CI: 0.843, 0.853]) vs 0.828 [95% CI: 0.817, 0.828]) compared with the baseline. Conclusion The addition of unlabeled data in a semi-supervised learning framework demonstrates stronger generalizability potential for intracranial hemorrhage detection and segmentation compared with a supervised baseline. <b>Keywords:</b> Semi-supervised Learning, Traumatic Brain Injury, CT, Machine Learning <i>Supplemental material is available for this article.</i> Published under a CC BY 4.0 license. See also the commentary by Swimburne in this issue.</p>","PeriodicalId":29787,"journal":{"name":"Radiology-Artificial Intelligence","volume":" ","pages":"e230077"},"PeriodicalIF":9.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140040505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Faster, More Practical, but Still Accurate: Deep Learning for Diagnosis of Progressive Supranuclear Palsy.","authors":"Bahram Mohajer","doi":"10.1148/ryai.240181","DOIUrl":"10.1148/ryai.240181","url":null,"abstract":"","PeriodicalId":29787,"journal":{"name":"Radiology-Artificial Intelligence","volume":"6 3","pages":"e240181"},"PeriodicalIF":9.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140513/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140858206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Semiautonomous Deep Learning System to Reduce False Positives in Screening Mammography.","authors":"Stefano Pedemonte, Trevor Tsue, Brent Mombourquette, Yen Nhi Truong Vu, Thomas Matthews, Rodrigo Morales Hoil, Meet Shah, Nikita Ghare, Naomi Zingman-Daniels, Susan Holley, Catherine M Appleton, Jason Su, Richard L Wahl","doi":"10.1148/ryai.230033","DOIUrl":"10.1148/ryai.230033","url":null,"abstract":"<p><p>Purpose To evaluate the ability of a semiautonomous artificial intelligence (AI) model to identify screening mammograms not suspicious for breast cancer and reduce the number of false-positive examinations. Materials and Methods The deep learning algorithm was trained using 123 248 two-dimensional digital mammograms (6161 cancers) and a retrospective study was performed on three nonoverlapping datasets of 14 831 screening mammography examinations (1026 cancers) from two U.S. institutions and one U.K. institution (2008-2017). The stand-alone performance of humans and AI was compared. Human plus AI performance was simulated to examine reductions in the cancer detection rate, number of examinations, false-positive callbacks, and benign biopsies. Metrics were adjusted to mimic the natural distribution of a screening population, and bootstrapped CIs and <i>P</i> values were calculated. Results Retrospective evaluation on all datasets showed minimal changes to the cancer detection rate with use of the AI device (noninferiority margin of 0.25 cancers per 1000 examinations: U.S. dataset 1, <i>P</i> = .02; U.S. dataset 2, <i>P</i> < .001; U.K. dataset, <i>P</i> < .001). On U.S. dataset 1 (11 592 mammograms; 101 cancers; 3810 female patients; mean age, 57.3 years ± 10.0 [SD]), the device reduced screening examinations requiring radiologist interpretation by 41.6% (95% CI: 40.6%, 42.4%; <i>P</i> < .001), diagnostic examinations callbacks by 31.1% (95% CI: 28.7%, 33.4%; <i>P</i> < .001), and benign needle biopsies by 7.4% (95% CI: 4.1%, 12.4%; <i>P</i> < .001). U.S. dataset 2 (1362 mammograms; 330 cancers; 1293 female patients; mean age, 55.4 years ± 10.5) was reduced by 19.5% (95% CI: 16.9%, 22.1%; <i>P</i> < .001), 11.9% (95% CI: 8.6%, 15.7%; <i>P</i> < .001), and 6.5% (95% CI: 0.0%, 19.0%; <i>P</i> = .08), respectively. The U.K. dataset (1877 mammograms; 595 cancers; 1491 female patients; mean age, 63.5 years ± 7.1) was reduced by 36.8% (95% CI: 34.4%, 39.7%; <i>P</i> < .001), 17.1% (95% CI: 5.9%, 30.1%: <i>P</i> < .001), and 5.9% (95% CI: 2.9%, 11.5%; <i>P</i> < .001), respectively. Conclusion This work demonstrates the potential of a semiautonomous breast cancer screening system to reduce false positives, unnecessary procedures, patient anxiety, and medical expenses. <b>Keywords:</b> Artificial Intelligence, Semiautonomous Deep Learning, Breast Cancer, Screening Mammography <i>Supplemental material is available for this article.</i> Published under a CC BY 4.0 license.</p>","PeriodicalId":29787,"journal":{"name":"Radiology-Artificial Intelligence","volume":" ","pages":"e230033"},"PeriodicalIF":9.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140506/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum for: Performance of the Winning Algorithms of the RSNA 2022 Cervical Spine Fracture Detection Challenge.","authors":"Ghee Rye Lee, Adam E Flanders, Tyler Richards, Felipe Kitamura, Errol Colak, Hui Ming Lin, Robyn L Ball, Jason Talbott, Luciano M Prevedello","doi":"10.1148/ryai.249002","DOIUrl":"10.1148/ryai.249002","url":null,"abstract":"","PeriodicalId":29787,"journal":{"name":"Radiology-Artificial Intelligence","volume":"6 3","pages":"e249002"},"PeriodicalIF":9.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140496/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140865979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence for Breast Cancer Screening: Trade-offs between Sensitivity and Specificity.","authors":"Manisha Bahl, Synho Do","doi":"10.1148/ryai.240184","DOIUrl":"10.1148/ryai.240184","url":null,"abstract":"","PeriodicalId":29787,"journal":{"name":"Radiology-Artificial Intelligence","volume":"6 3","pages":"e240184"},"PeriodicalIF":9.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140497/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140877471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Noninvasive Molecular Subtyping of Pediatric Low-Grade Glioma with Self-Supervised Transfer Learning.","authors":"Divyanshu Tak, Zezhong Ye, Anna Zapaischykova, Yining Zha, Aidan Boyd, Sridhar Vajapeyam, Rishi Chopra, Hasaan Hayat, Sanjay P Prabhu, Kevin X Liu, Hesham Elhalawani, Ali Nabavizadeh, Ariana Familiar, Adam C Resnick, Sabine Mueller, Hugo J W L Aerts, Pratiti Bandopadhayay, Keith L Ligon, Daphne A Haas-Kogan, Tina Y Poussaint, Benjamin H Kann","doi":"10.1148/ryai.230333","DOIUrl":"10.1148/ryai.230333","url":null,"abstract":"<p><p>Purpose To develop and externally test a scan-to-prediction deep learning pipeline for noninvasive, MRI-based <i>BRAF</i> mutational status classification for pediatric low-grade glioma. Materials and Methods This retrospective study included two pediatric low-grade glioma datasets with linked genomic and diagnostic T2-weighted MRI data of patients: Dana-Farber/Boston Children's Hospital (development dataset, <i>n</i> = 214 [113 (52.8%) male; 104 (48.6%) <i>BRAF</i> wild type, 60 (28.0%) <i>BRAF</i> fusion, and 50 (23.4%) <i>BRAF</i> V600E]) and the Children's Brain Tumor Network (external testing, <i>n</i> = 112 [55 (49.1%) male; 35 (31.2%) <i>BRAF</i> wild type, 60 (53.6%) <i>BRAF</i> fusion, and 17 (15.2%) <i>BRAF</i> V600E]). A deep learning pipeline was developed to classify <i>BRAF</i> mutational status (<i>BRAF</i> wild type vs <i>BRAF</i> fusion vs <i>BRAF</i> V600E) via a two-stage process: <i>(a)</i> three-dimensional tumor segmentation and extraction of axial tumor images and <i>(b)</i> section-wise, deep learning-based classification of mutational status. Knowledge-transfer and self-supervised approaches were investigated to prevent model overfitting, with a primary end point of the area under the receiver operating characteristic curve (AUC). To enhance model interpretability, a novel metric, center of mass distance, was developed to quantify the model attention around the tumor. Results A combination of transfer learning from a pretrained medical imaging-specific network and self-supervised label cross-training (TransferX) coupled with consensus logic yielded the highest classification performance with an AUC of 0.82 (95% CI: 0.72, 0.91), 0.87 (95% CI: 0.61, 0.97), and 0.85 (95% CI: 0.66, 0.95) for <i>BRAF</i> wild type, <i>BRAF</i> fusion, and <i>BRAF</i> V600E, respectively, on internal testing. On external testing, the pipeline yielded an AUC of 0.72 (95% CI: 0.64, 0.86), 0.78 (95% CI: 0.61, 0.89), and 0.72 (95% CI: 0.64, 0.88) for <i>BRAF</i> wild type, <i>BRAF</i> fusion, and <i>BRAF</i> V600E, respectively. Conclusion Transfer learning and self-supervised cross-training improved classification performance and generalizability for noninvasive pediatric low-grade glioma mutational status prediction in a limited data scenario. <b>Keywords:</b> Pediatrics, MRI, CNS, Brain/Brain Stem, Oncology, Feature Detection, Diagnosis, Supervised Learning, Transfer Learning, Convolutional Neural Network (CNN) <i>Supplemental material is available for this article.</i> © RSNA, 2024.</p>","PeriodicalId":29787,"journal":{"name":"Radiology-Artificial Intelligence","volume":" ","pages":"e230333"},"PeriodicalIF":8.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140040504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}