Urologie最新文献_第8页

[Specialized ambulatory palliative care for urological tumors]. 泌尿系统肿瘤的专科门诊姑息治疗。

IF 0.5 4区医学

Urologie Pub Date : 2025-08-01 Epub Date: 2025-04-04 DOI: 10.1007/s00120-025-02573-x

Stephan Degener, Nici Markus Dreger, Friedrich-Carl von Rundstedt, Marie-Therese Schmitz, Ulrich Grabenhorst, Oliver Schmalz, Klaus Weckbecker, Johannes Just

{"title":"[Specialized ambulatory palliative care for urological tumors].","authors":"Stephan Degener, Nici Markus Dreger, Friedrich-Carl von Rundstedt, Marie-Therese Schmitz, Ulrich Grabenhorst, Oliver Schmalz, Klaus Weckbecker, Johannes Just","doi":"10.1007/s00120-025-02573-x","DOIUrl":"10.1007/s00120-025-02573-x","url":null,"abstract":"Background: Urologic tumors comprise about 20% of cancer diagnoses in Germany. To date, there are no studies with large datasets on the palliative situation of patients with urological tumors in the home environment, although dignified end-of-life care in the home environment is the wish of most cancer patients.Methods: Data from 5125 patients who received specialized outpatient palliative care (SAPV) with an underlying urological cancer between 2017 and 2021 were included in the analysis.Result: The analysis showed that 91.5% of patients died at home and the symptom burden remained stable or decreased slightly during treatment. The median survival time of patients receiving SAPV was 24 days. Factors such as age, performance status, loss of appetite, weakness, and pain at the start of treatment influenced the survival time of the patients. Relatives were largely very satisfied with the care provided.Conclusion: The study provides important insights into the palliative care of patients with urological tumors and underlines the importance of SAPV for dignified end-of-life care.","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"784-792"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Visualizing the 'unspeakable': venereal diseases at the 1926 GeSoLei (Great Exhibition for Health Care, Social Welfare, and Physical Exercise)]. [在1926年GeSoLei（卫生保健、社会福利和体育锻炼大展览）上可视化“无法形容的”性病]。

IF 0.5 4区医学

Urologie Pub Date : 2025-08-01 Epub Date: 2025-06-20 DOI: 10.1007/s00120-025-02633-2

Matthis Krischel, Sarah Czirr, Friedrich H Moll

{"title":"[Visualizing the 'unspeakable': venereal diseases at the 1926 GeSoLei (Great Exhibition for Health Care, Social Welfare, and Physical Exercise)].","authors":"Matthis Krischel, Sarah Czirr, Friedrich H Moll","doi":"10.1007/s00120-025-02633-2","DOIUrl":"10.1007/s00120-025-02633-2","url":null,"abstract":"The GeSoLei (Great Exhibition for Health Care, Social Welfare, and Physical Exercise) held in Düsseldorf in 1926 was one of the largest exhibitions of the Weimar Republic. At its core was the often visual communication of health-related topics-including the presentation of sexually transmitted diseases. These subjects were conveyed within the complex interplay between medical education, moral normalization, and esthetic staging. The section \"Common Diseases, Common Ailments, Common Vices\" (Main Section Social Welfare) brought together conditions such as tuberculosis, alcoholism, and syphilis-sicknesses that were not only medically, but also socially and morally charged. Through the use of information boards, wax models (moulages), and interactive exhibits, connections between sexuality, disease, and social responsibility were emphasized. The visual strategy followed a pedagogical and often deterrent approach, which, through standardized forms of representation, enabled communication suited for a mass audience. In addition to the guiding principle of social hygiene, the exhibition also incorporated ideas of racial and hereditary health, placing sexually transmitted diseases within the context of \"public health\" and \"rational population management.\" However, aspects of sexual diversity or sexology-as advocated by figures like Magnus Hirschfeld-were deliberately excluded. This article analyzes the visual and conceptual presentation of sexually transmitted diseases at GeSoLei as a representative example of the medicalization and moralization of sexuality in the early 20th century-embedded in a complex web of science, society, politics, and aesthetics.","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"815-824"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12287214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Prophylaxis of recurrent urinary tract infections by nitroxoline-real-world data of the ProNitrox study]. [硝基啉预防复发性尿路感染- proitrox研究的真实数据]。

IF 0.4 4区医学

Urologie Pub Date : 2025-07-28 DOI: 10.1007/s00120-025-02641-2

A Wiedemann, F Wagenlehner, K Naber, W Strohmaier, W Vahlensieck, R Kirschner-Hermanns, A Bannowsky, S Wirz, J Salem, T Kuru

{"title":"[Prophylaxis of recurrent urinary tract infections by nitroxoline-real-world data of the ProNitrox study].","authors":"A Wiedemann, F Wagenlehner, K Naber, W Strohmaier, W Vahlensieck, R Kirschner-Hermanns, A Bannowsky, S Wirz, J Salem, T Kuru","doi":"10.1007/s00120-025-02641-2","DOIUrl":"https://doi.org/10.1007/s00120-025-02641-2","url":null,"abstract":"Background: For recurrent urinary tract infections (rUTI), nitroxoline, a hydroxyquinoline derivative with low resistance rates, can be used for long-term prophylaxis (LP). There is little data available on this so far. The clinical routine of LP with nitroxoline was to be assessed in a retrospective, noninterventional study under real-world conditions. In addition to demographic data, the extent of multimorbidity, existing risk factors for rUTI, the type of antibiotic therapy of the last acute episode of rUTI, and the rate of breakthrough infections were of particular interest.Materials and methods: In the period April-October 2024, data from 360 patients who received reinfection prophylaxis with nitroxoline for rUTI from 70 doctors were collected.Results: The rate of breakthrough infections was 13% and was predominantly determined from urine culture. Of the documented patients, 20% (women) and 47% (men) were classified as multimorbid and 32% (women) and 48% (men) were classified as geriatric. Furthermore, 31.6% of patients had complicating factors for rUTI. The duration of therapy with nitroxoline was usually 3-6 months, in rare cases more than 2 years.Conclusion: The high number of comorbidities, older age, the high proportion of complicating factors such as urinary tract abnormalities and the use of antibiotics in the last acute episode, which are not intended for LP of rUTI, characterize the present patient group as difficult. Nevertheless, there is a favorable recurrence rate of 13%. The most frequently cited reasons for choosing nitroxoline for LP were good tolerability and effectiveness, the level of resistance and the therapist's positive experiences.","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Establishment of a university urological clinic in Germany using Ulm as an example: background]. [在德国建立大学泌尿科诊所，以乌尔姆为例：背景]。

IF 0.5 4区医学

Urologie Pub Date : 2025-07-22 DOI: 10.1007/s00120-025-02654-x

Richard E Hautmann

{"title":"[Establishment of a university urological clinic in Germany using Ulm as an example: background].","authors":"Richard E Hautmann","doi":"10.1007/s00120-025-02654-x","DOIUrl":"https://doi.org/10.1007/s00120-025-02654-x","url":null,"abstract":"The University of Ulm was founded in 1967. Except for the Department of Urology all other specialities of the existing municipal hospital joined the University Medical Center. At that time, the department of urology was-with > 250 beds-the world's largest urology department. There is conflicting historical data, but based on new information the first chairperson took office in July 1984. Initially the Department of Urology was a section of the Surgical Center, but it quickly attained the status of an independent University Urology Clinic. The clinic was a well-known transurethral resection of the prostate (TUR-P) center (Hösel, Marquardt), which evolved to include, among other things, an extracorporeal shock wave lithotripsy (ESWL) center and most notably an oncologic surgery, pioneering the development of the ileal neobladder (INB). The term \"neobladder\" was coined in Ulm. Large annual live surgeries and operative teaching seminars, and more than 100 visiting professors in Ulm popularized the INB technique and enhanced the clinic's reputation. Significant structural improvements included expanded operating capacity, which was facilitated by 4 operating rooms exclusively for the use of Department of Urology and a dedicated urology intensive care unit jointly managed by anesthesiologists and urologists. The staff of the department increased significantly with external reinforcement by senior physicians from other institutes, and ultimately 4 chairmen of renowned departments (Berlin, Charité, Munich, Klinikum rechts der Isar, Gainsville, Florida, USA, and Bangkok, Thailand) emerged from Ulm as well as numerous heads of national urology departments (e.g., in Karlsruhe, Kassel, and Wiesbaden).","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144691722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Interrupting the spread of germs : The art of emptying urinary drainage bags]. [阻断细菌的传播：排空排尿袋的艺术]。

IF 0.5 4区医学

Urologie Pub Date : 2025-07-11 DOI: 10.1007/s00120-025-02644-z

Uwe Ernsberger

{"title":"[Interrupting the spread of germs : The art of emptying urinary drainage bags].","authors":"Uwe Ernsberger","doi":"10.1007/s00120-025-02644-z","DOIUrl":"https://doi.org/10.1007/s00120-025-02644-z","url":null,"abstract":"Background: Due to the development of antibiotic resistance in many bacterial species, the demands in nursing care have changed significantly. In handling urine catheters in home care, ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp.) pathogens may present as urinary tract infections or in bacteriuria. However, increasing challenges in hygiene and infection prevention is faced by an increasing number of health assistants and aides with limited knowledge on pathogen systematics, bacterial reservoirs, and pathogen spread.Methods: The use of hygiene aids during preparation and emptying the urinary drainage bag for a tetraplegic disabled person were observed and recorded.Results: The advantages of using disinfection wipes by nursing personnel and aides during emptying of urine bags is encouraging. Rapid accessibility of well-placed wipes increases the frequency of reaching several times for a wipe during a critical workflow, compared to the use of a dispenser for hand disinfection. Potentially contaminating touches from the urine outlet or bucket into the area around the bed, or the use of the working hand to touch the glasses, hair, or clothes of the nurse are largely reduced. The touching of the bathroom faucet with a potentially contaminated glove is replaced by reaching for a disinfectant wipe.Conclusion: By preventing the use of a contaminated hand in an area that needs to remain hygienic by reaching for a disinfectant wipe potentially stops the spread of pathogens. The frequent and deliberative use of wipes significantly reduces the risk of pathogen spread in a home nursing environment.","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Adjuvant immunotherapy with pembrolizumab for renal cell carcinoma-is the new standard of care cost-effective?? : A health economic analysis]. pembrolizumab辅助免疫治疗肾细胞癌——新的治疗标准是否具有成本效益？[健康经济分析]。

IF 0.5 4区医学

Urologie Pub Date : 2025-07-10 DOI: 10.1007/s00120-025-02632-3

Sarah Katharina Assiba Weiß, Carsten Lange, Nicole Hübscher, Abdullah Al Hasan, Steffen Hallmann, Tobias Klatte

{"title":"[Adjuvant immunotherapy with pembrolizumab for renal cell carcinoma-is the new standard of care cost-effective?? : A health economic analysis].","authors":"Sarah Katharina Assiba Weiß, Carsten Lange, Nicole Hübscher, Abdullah Al Hasan, Steffen Hallmann, Tobias Klatte","doi":"10.1007/s00120-025-02632-3","DOIUrl":"https://doi.org/10.1007/s00120-025-02632-3","url":null,"abstract":"Background: Adjuvant pembrolizumab decreases the risk of recurrence and prolongs survival after surgery for high-risk clear cell renal cell carcinoma. Cost-effectiveness analyses evaluate therapy associated risks, toxicity, quality of life, costs of therapies and follow-up regimens and represent an essential adjunct for the evaluation of new therapies. At present, there is no cost effectiveness analysis for adjuvant pembrolizumab within the German healthcare system.Methods: A Markov model was used to evaluate cost-effectiveness. The impact of variables on the cost-effectiveness of therapy were investigated with one-way deterministic and probabilistic sensitivity analysis and thresholds were determined.Results: The adjuvant treatment with pembrolizumab was cost-effective over a 5-year period, with an ICER (incremental cost-effectiveness ratio) of 68,278 €/QALY (quality-adjusted life year) assuming a WTP (willingness to pay) threshold of 100,000 €/QALY.Conclusion: Adjuvant treatment in high-risk patients with pembrolizumab has been shown to be cost-effective when applied within the German health system. It should therefore be offered to all patients with an increased risk for recurrence after curative surgery.","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Innovative systemic treatment approaches for advanced penile cancer]. 【晚期阴茎癌的创新系统治疗方法】。

IF 0.5 4区医学

Urologie Pub Date : 2025-07-01 Epub Date: 2025-05-19 DOI: 10.1007/s00120-025-02605-6

Désirée L Dräger

引用次数: 0

[Multimorbidity-implications for nursing care]. [多发病-护理的含义]。

IF 0.5 4区医学

Urologie Pub Date : 2025-07-01 Epub Date: 2025-02-11 DOI: 10.1007/s00120-025-02540-6

Michael Tiemann

引用次数: 0

["Die Ärzte für Afrika e. V."-urological missions and training in Ghana]. [Die Ärzte für Afrika e. V.--加纳的神经学任务和培训]。

IF 0.5 4区医学

Urologie Pub Date : 2025-07-01 Epub Date: 2025-03-18 DOI: 10.1007/s00120-025-02565-x

Jessica Rührup

引用次数: 0

[Boys' health from a urologic perspective]. [从泌尿学角度看男孩的健康]。

IF 0.5 4区医学

Urologie Pub Date : 2025-07-01 Epub Date: 2025-04-29 DOI: 10.1007/s00120-025-02596-4

Jens Rosellen, Petra Anheuser

引用次数: 0