Leonhard Buck, Hans Christoph von Knobloch, Jakob Kohler, Fatih Yalcin, Christiane Maria Stuhlmann-Laeisz, Severin Rodler, Jonas Jarczyk, Philipp Nuhn
{"title":"[First diagnosis of renal cell carcinoma via a testicular metastasis].","authors":"Leonhard Buck, Hans Christoph von Knobloch, Jakob Kohler, Fatih Yalcin, Christiane Maria Stuhlmann-Laeisz, Severin Rodler, Jonas Jarczyk, Philipp Nuhn","doi":"10.1007/s00120-025-02584-8","DOIUrl":null,"url":null,"abstract":"<p><p>This case report describes a rare case of testicular metastasis from renal cell carcinoma, which led to first diagnosis of the primary. The patient presented with a progressive painless swelling of the left testicle. After initial suspicion of a testicular tumor, inguinal excision of the testis was performed, which confirmed the presence of a clear cell carcinoma. Further investigations revealed evidence of a primary carcinoma on the left-lower pole of the kidney, which was removed by partial nephrectomy. Histopathologically, clear cell renal cell carcinoma was confirmed. Treatment was supplemented by adjuvant immunotherapy with pembrolizumab. Postoperative follow-up has shown no evidence of recurrence to date.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":""},"PeriodicalIF":0.5000,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Urologie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s00120-025-02584-8","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
This case report describes a rare case of testicular metastasis from renal cell carcinoma, which led to first diagnosis of the primary. The patient presented with a progressive painless swelling of the left testicle. After initial suspicion of a testicular tumor, inguinal excision of the testis was performed, which confirmed the presence of a clear cell carcinoma. Further investigations revealed evidence of a primary carcinoma on the left-lower pole of the kidney, which was removed by partial nephrectomy. Histopathologically, clear cell renal cell carcinoma was confirmed. Treatment was supplemented by adjuvant immunotherapy with pembrolizumab. Postoperative follow-up has shown no evidence of recurrence to date.