UrologiePub Date : 2025-07-14DOI: 10.1007/s00120-025-02651-0
Emily Rinderknecht, R Alexa, N Carl, M Goertz, F Wessels, H Borgmann
{"title":"[Digital urology : Possible uses for artificial intelligence and digital health applications].","authors":"Emily Rinderknecht, R Alexa, N Carl, M Goertz, F Wessels, H Borgmann","doi":"10.1007/s00120-025-02651-0","DOIUrl":"https://doi.org/10.1007/s00120-025-02651-0","url":null,"abstract":"<p><strong>Background: </strong>Urology presents itself as a modern and future-oriented discipline. Artificial intelligence (AI) is becoming increasingly important in the field of digital urology. It enables the analysis of large medical data sets, such as histological patterns, imaging or molecular markers. In addition, large language models (LLMs) are opening up new fields of application. Digital health applications (DiGA) are also becoming increasingly important.</p><p><strong>Objectives: </strong>This article provides an overview of current developments in digital urology. The focus is on the possible applications of AI and LLMs, taking into account the legal and ethical framework, as well as an overview of the therapeutic landscape of DiGA in urological care.</p><p><strong>Methods: </strong>Existing AI models and applications will be presented and analyzed. In addition, DiGA in urological care and current regulatory requirements are discussed.</p><p><strong>Results: </strong>AI systems can improve many areas of urology-for example through automated evaluation of image morphology and histology data or voice-based applications in documentation and communication. DiGA support the follow-up care and treatment of urological diseases. Their use requires transparency, data protection, and quality assurance.</p><p><strong>Conclusion: </strong>AI and digital applications offer new care models and can help to increase efficiency. Challenges exist in terms of data quality, information technology infrastructure and the safe and responsible use of technologies. Future developments should be interdisciplinary.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-07-11DOI: 10.1007/s00120-025-02644-z
Uwe Ernsberger
{"title":"[Interrupting the spread of germs : The art of emptying urinary drainage bags].","authors":"Uwe Ernsberger","doi":"10.1007/s00120-025-02644-z","DOIUrl":"https://doi.org/10.1007/s00120-025-02644-z","url":null,"abstract":"<p><strong>Background: </strong>Due to the development of antibiotic resistance in many bacterial species, the demands in nursing care have changed significantly. In handling urine catheters in home care, ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp.) pathogens may present as urinary tract infections or in bacteriuria. However, increasing challenges in hygiene and infection prevention is faced by an increasing number of health assistants and aides with limited knowledge on pathogen systematics, bacterial reservoirs, and pathogen spread.</p><p><strong>Methods: </strong>The use of hygiene aids during preparation and emptying the urinary drainage bag for a tetraplegic disabled person were observed and recorded.</p><p><strong>Results: </strong>The advantages of using disinfection wipes by nursing personnel and aides during emptying of urine bags is encouraging. Rapid accessibility of well-placed wipes increases the frequency of reaching several times for a wipe during a critical workflow, compared to the use of a dispenser for hand disinfection. Potentially contaminating touches from the urine outlet or bucket into the area around the bed, or the use of the working hand to touch the glasses, hair, or clothes of the nurse are largely reduced. The touching of the bathroom faucet with a potentially contaminated glove is replaced by reaching for a disinfectant wipe.</p><p><strong>Conclusion: </strong>By preventing the use of a contaminated hand in an area that needs to remain hygienic by reaching for a disinfectant wipe potentially stops the spread of pathogens. The frequent and deliberative use of wipes significantly reduces the risk of pathogen spread in a home nursing environment.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-07-10DOI: 10.1007/s00120-025-02632-3
Sarah Katharina Assiba Weiß, Carsten Lange, Nicole Hübscher, Abdullah Al Hasan, Steffen Hallmann, Tobias Klatte
{"title":"[Adjuvant immunotherapy with pembrolizumab for renal cell carcinoma-is the new standard of care cost-effective?? : A health economic analysis].","authors":"Sarah Katharina Assiba Weiß, Carsten Lange, Nicole Hübscher, Abdullah Al Hasan, Steffen Hallmann, Tobias Klatte","doi":"10.1007/s00120-025-02632-3","DOIUrl":"https://doi.org/10.1007/s00120-025-02632-3","url":null,"abstract":"<p><strong>Background: </strong>Adjuvant pembrolizumab decreases the risk of recurrence and prolongs survival after surgery for high-risk clear cell renal cell carcinoma. Cost-effectiveness analyses evaluate therapy associated risks, toxicity, quality of life, costs of therapies and follow-up regimens and represent an essential adjunct for the evaluation of new therapies. At present, there is no cost effectiveness analysis for adjuvant pembrolizumab within the German healthcare system.</p><p><strong>Methods: </strong>A Markov model was used to evaluate cost-effectiveness. The impact of variables on the cost-effectiveness of therapy were investigated with one-way deterministic and probabilistic sensitivity analysis and thresholds were determined.</p><p><strong>Results: </strong>The adjuvant treatment with pembrolizumab was cost-effective over a 5-year period, with an ICER (incremental cost-effectiveness ratio) of 68,278 €/QALY (quality-adjusted life year) assuming a WTP (willingness to pay) threshold of 100,000 €/QALY.</p><p><strong>Conclusion: </strong>Adjuvant treatment in high-risk patients with pembrolizumab has been shown to be cost-effective when applied within the German health system. It should therefore be offered to all patients with an increased risk for recurrence after curative surgery.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-07-09DOI: 10.1007/s00120-025-02642-1
K Kastrati, M Wartenberg
{"title":"[Shaping the future of oncology together : How genuine participation, more user focus, and partnership at eye level can change cancer medicine].","authors":"K Kastrati, M Wartenberg","doi":"10.1007/s00120-025-02642-1","DOIUrl":"https://doi.org/10.1007/s00120-025-02642-1","url":null,"abstract":"<p><p>Oncology in Germany is on the brink of a necessary transformation: from self-help and occasional patient consultation toward genuine, structured patient involvement. Patients are not merely recipients of medical services but active users-with insights that can significantly improve research, care, digital innovation, and health policy. International examples show that co-creation is becoming the standard. Germany is also making initial progress, for instance, through the National Decade Against Cancer. What is needed now are nationwide structures, training, resources-and a mindset that recognizes patients as equal partners. In doing so, oncology can lead the way toward a new, participatory healthcare culture.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-07-01Epub Date: 2025-03-18DOI: 10.1007/s00120-025-02565-x
Jessica Rührup
{"title":"[\"Die Ärzte für Afrika e. V.\"-urological missions and training in Ghana].","authors":"Jessica Rührup","doi":"10.1007/s00120-025-02565-x","DOIUrl":"10.1007/s00120-025-02565-x","url":null,"abstract":"","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"696-699"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-07-01Epub Date: 2025-04-29DOI: 10.1007/s00120-025-02596-4
Jens Rosellen, Petra Anheuser
{"title":"[Boys' health from a urologic perspective].","authors":"Jens Rosellen, Petra Anheuser","doi":"10.1007/s00120-025-02596-4","DOIUrl":"10.1007/s00120-025-02596-4","url":null,"abstract":"<p><p>Boys' health and health promotion are crucial for preventing diseases in later life. Urology can take preventive action in all areas of male development, sexuality, and reproduction. This includes imparting knowledge about normal puberty development and general health care measures but also encompasses sex education about contraceptives and sexually transmitted diseases. This may include a focused physical examination and a check of vaccination protection. In order to implement these measures and to facilitate reaching the target group, it is useful to create specific advice services such as a boys' consultation hour. The content and depth of the conversation should be based on the life situation and prior knowledge of the person seeking advice. In this way, urology can also be a competent contact for questions about men's health in later phases of life.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"645-652"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144038645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-07-01Epub Date: 2025-05-09DOI: 10.1007/s00120-025-02601-w
Pia Paffenholz
{"title":"[Pediatric testicular tumors].","authors":"Pia Paffenholz","doi":"10.1007/s00120-025-02601-w","DOIUrl":"10.1007/s00120-025-02601-w","url":null,"abstract":"<p><strong>Background: </strong>Testicular tumors are rare in childhood but differ significantly from adult forms in terms of etiology, histology, and prognosis. Early diagnosis and appropriate treatment are crucial for the prognosis and quality of life of affected children.</p><p><strong>Objective: </strong>The aim of this article is to provide an overview of the etiology, classification, clinical presentation, diagnostic tests, and treatment of pediatric testicular tumors.</p><p><strong>Materials and methods: </strong>This article is based on an analysis of current literature.</p><p><strong>Results: </strong>Pediatric testicular tumors are benign in 60-75% of cases, most commonly teratomas or Leydig cell tumors. Malignant tumors such as yolk sac tumors are rare and show low metastatic potential. Diagnostics include ultrasound, tumor markers (AFP, hCG, LDH), and imaging (MRI, CT). Treatment consists of organ-sparing surgery in suspected benign cases and orchiectomy in malignant cases. Chemotherapy is reserved for metastatic tumors. In localized stage I disease, surveillance is often sufficient.</p><p><strong>Conclusion: </strong>Pediatric germ cell tumors differ from adult testicular tumors in terms of incidence, malignancy, and histology. Treatment decisions should always be made within an interdisciplinary framework.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"660-663"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-07-01Epub Date: 2025-05-26DOI: 10.1007/s00120-025-02599-1
Annette Schröder
{"title":"[Pediatric urology-common issues of the external genitalia in boys].","authors":"Annette Schröder","doi":"10.1007/s00120-025-02599-1","DOIUrl":"10.1007/s00120-025-02599-1","url":null,"abstract":"<p><p>In infant and young boys there are numerous (sometimes only assumed) abnormalities of the external genitalia, which may lead to a consultation in a urologists' office. Some are perfectly harmless and require only explanation and reassurance while others require careful consideration and complex reconstruction. Knowledge of the contemporary approaches to these issues, which may have changed considerably over the last decades, are equally important as careful avoidance of generalized statements regarding potential threats to fertility or risks of cancer in future life. The current article aims to give an overview of the most common complaints of the external genitalia in young and adolescent boys.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"653-659"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}