UrologiePub Date : 2025-07-01Epub Date: 2025-06-26DOI: 10.1007/s00120-025-02602-9
Joachim Steffens, Petra Anheuser, Jennifer Kranz
{"title":"[Boys' consultation-the urologist as a boys' physician].","authors":"Joachim Steffens, Petra Anheuser, Jennifer Kranz","doi":"10.1007/s00120-025-02602-9","DOIUrl":"https://doi.org/10.1007/s00120-025-02602-9","url":null,"abstract":"","PeriodicalId":29782,"journal":{"name":"Urologie","volume":"64 7","pages":"633-635"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-07-01Epub Date: 2025-05-21DOI: 10.1007/s00120-025-02606-5
Thorsten H Ecke
{"title":"[Successful implementation of screening for urothelial carcinoma of the upper and lower urinary tract-a critical evaluation of urine-based lateral flow tests].","authors":"Thorsten H Ecke","doi":"10.1007/s00120-025-02606-5","DOIUrl":"10.1007/s00120-025-02606-5","url":null,"abstract":"","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"713-714"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144120790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-07-01Epub Date: 2025-06-23DOI: 10.1007/s00120-025-02577-7
F Abd Ali, P Vincze, T R W Herrmann, C Netsch, B Becker, G Hatiboglu, R Homberg, K Lehrich, A Miernik, P Olbert, D S Schöb, J Herrmann, J A Gross, L Lusuardi, Karl-Dietrich Sievert
{"title":"[Stones in the lower pole and their treatment].","authors":"F Abd Ali, P Vincze, T R W Herrmann, C Netsch, B Becker, G Hatiboglu, R Homberg, K Lehrich, A Miernik, P Olbert, D S Schöb, J Herrmann, J A Gross, L Lusuardi, Karl-Dietrich Sievert","doi":"10.1007/s00120-025-02577-7","DOIUrl":"10.1007/s00120-025-02577-7","url":null,"abstract":"<p><p>The most frequent initial clinical symptom is flank pain, which occurs in approximately half of affected patients with stones of the upper urinary tract. Of these patients approximately half require treatment and 50% will again have new stones in the future. Only 8% of urinary stones are clinically inapparent with 25-50% of the stones located in the lower calyx group and are incidentally discovered during the diagnostics of symptomatic stones. Stones in the lower calyx are more difficult to treat than other kidney stones due to the localization and the resulting access possibilities. The treatment must therefore be planned and carried out individually according to the available treatment options. Since the development of modern flexible ureterorenoscopes (URS) retrograde stone removal, which has few complications, has been highly valued in the treatment of stones of the lower calyx due to the desired primary stone clearance rates. Limiting factors are the longer treatment times for large stone masses and the considerable material costs. Furthermore, the various forms of percutaneous nephrolitholapaxy provide additional methods for the treatment of larger lower caliceal stones.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"715-724"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-07-01Epub Date: 2025-03-11DOI: 10.1007/s00120-025-02557-x
Laila Schneidewind, Barbara Sommerhalder, Dario Willi, Cindy Rönnau, Annemarie Uhlig, Bernhard Kiss
{"title":"[Association of glitazones and bladder cancer: a rapid review].","authors":"Laila Schneidewind, Barbara Sommerhalder, Dario Willi, Cindy Rönnau, Annemarie Uhlig, Bernhard Kiss","doi":"10.1007/s00120-025-02557-x","DOIUrl":"10.1007/s00120-025-02557-x","url":null,"abstract":"<p><strong>Background: </strong>Since the authorization of glitazones as oral antidiabetics, there has been a controversial debate as to whether they increase the risk of bladder cancer or accelerate its progression. Recent data have shown that glitazones can upregulate the expression of Nectin4.</p><p><strong>Objectives: </strong>These results make a renewed detailed examination of the topic unavoidable. Consequently, we conducted a rapid evidence analysis. The primarily aim was to identify systematic reviews investigating this relationship. Second, translational studies that describe the molecular biological background were identified.</p><p><strong>Materials and methods: </strong>A rapid evidence analysis was conducted with a literature search in MEDLINE via PubMed for the period July 2000 (first approval of glitazones in the European Union) to the date of the last search (15 July 2024).</p><p><strong>Results: </strong>The primary literature search yielded 860 hits and ultimately 14 studies were included. Of these, 6 were systematic reviews (5 including meta-analyses) and 8 were translational studies. In the reviews, the data situation regarding the association of glitazones with bladder cancer remains ambiguous, particularly due to the heterogeneity of the underlying studies and numerous confounding factors such as age or smoking history. Experimental evidence of a causal relationship between glitazones and bladder cancer could not be demonstrated. Two included studies even see a possible therapeutic benefit of the preparations in these patients.</p><p><strong>Conclusion: </strong>It remains unclear whether glitazones play a relevant role in the development of bladder cancer. The possible therapeutic benefit should be urgently investigated further.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"669-677"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12202691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-07-01Epub Date: 2025-04-30DOI: 10.1007/s00120-025-02597-3
Julius Benedikt Schneede, Peter Schneede
{"title":"[Human papillomavirus (HPV) vaccination for cancer prevention].","authors":"Julius Benedikt Schneede, Peter Schneede","doi":"10.1007/s00120-025-02597-3","DOIUrl":"10.1007/s00120-025-02597-3","url":null,"abstract":"<p><strong>Background: </strong>In 2005, the first approval study of a preventive quadrivalent human papillomavirus (HPV) vaccine in young women triggered vaccination strategies around the world.</p><p><strong>Objective: </strong>We aimed to investigate how successful these vaccination interventions have been in preventing cancer so far.</p><p><strong>Methods: </strong>To this end, we reviewed the relevant literature of the past two decades regarding vaccination rates and the subsequent decline in HPV-associated diseases worldwide.</p><p><strong>Results: </strong>For various reasons, many countries that offer HPV vaccinations are still missing their goals for primary cancer prevention. In Germany, for example, vaccination rates are completely inadequate, and urologists are not even recognized as vaccinators.</p><p><strong>Conclusion: </strong>Cancer prevention through HPV vaccination is zur Hausen's scientific legacy to the world. However, each country must continuously analyze and combat its specific reasons for failing in HPV vaccination. New HPV vaccines will continue the global success story in the future.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"664-668"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-07-01Epub Date: 2025-06-06DOI: 10.1007/s00120-025-02614-5
Julia Nebe, Matthis Krischel
{"title":"[Invisible in the culture of remembrance in medicine? The Dresden-based urologist and venereologist Dora Gerson (1884-1941) was persecuted because of her Jewish heritage].","authors":"Julia Nebe, Matthis Krischel","doi":"10.1007/s00120-025-02614-5","DOIUrl":"10.1007/s00120-025-02614-5","url":null,"abstract":"<p><p>The history of urology is traditionally considered to be male-dominated. However, the field has never been exclusively \"male medicine\"-neither in terms of patients nor medical staff. This article highlights the life and work of Dresden-based physician Dora Gerson (1884-1941), one of the first German female specialists in urology and dermatovenereology, and draws attention to the widespread invisibility of women in the culture of memory of the field. Gerson studied medicine in Munich and Leipzig at the beginning of the 20th century and worked in both clinical and social medicine in the following years. In her Dresden practice, she combined urology, dermatology, and venereology, while also running a public counseling center for women with sexually transmitted diseases. In 1933, Gerson's health insurance license was revoked, and she was forced to close her practice. From 1940 onward, she worked as a Jewish \"medical practitioner\" at the horticultural school in Ahlem, Hannover. In September 1941, under increasing pressure from repression, she took her own life. Her biography exemplifies a dual marginalization: as a member of a structurally disadvantaged gender and as a victim of Nazi persecution. The article connects Gerson's life story with issues of gender, memory culture, and recognition practices in medicine. It demonstrates how professional cultural memory functions selectively and explores how social background, gender, and political circumstances influence visibility and oblivion in medical history. The reflection on Dora Gerson's history thus also represents a critically reflective culture of remembrance within urology.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"686-695"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12202566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-07-01Epub Date: 2025-06-20DOI: 10.1007/s00120-025-02617-2
Panagiotis Angelopoulos, Panagiotis Neofytoy, Stamatios Katsimperis, Panagiotis Triantafylloy, Ioannis Manolitsis, Michael Lardas, Titos Markopoulos, Ioannis Varkarakis, Lazaros Tzelves, Andreas Skolarikos
{"title":"Metabolic evaluation of urolithiasis: a narrative review.","authors":"Panagiotis Angelopoulos, Panagiotis Neofytoy, Stamatios Katsimperis, Panagiotis Triantafylloy, Ioannis Manolitsis, Michael Lardas, Titos Markopoulos, Ioannis Varkarakis, Lazaros Tzelves, Andreas Skolarikos","doi":"10.1007/s00120-025-02617-2","DOIUrl":"10.1007/s00120-025-02617-2","url":null,"abstract":"<p><p>Urolithiasis is a common condition with high recurrence rates, often driven by metabolic abnormalities, dietary habits, and systemic disorders. Metabolic evaluation plays a key role in identifying modifiable risk factors such as hypercalciuria, hyperoxaluria, hypocitraturia, and hyperuricosuria. Despite its clinical value, metabolic evaluation remains underused in practice. This narrative review highlights the rationale, methods, and therapeutic implications of metabolic assessment in patients with recurrent or high-risk stone disease. The evaluation includes medical and dietary history, physical examination, blood and urine tests, 24‑h urine collections, and stone analysis. Tailored interventions-ranging from dietary advice to pharmacologic treatments such as thiazides, potassium citrate, and allopurinol-can reduce stone recurrence and prevent complications such as chronic kidney disease. Ongoing follow-up is essential to assess treatment response and modify strategies. Adherence to current guidelines and broader implementation of metabolic workup can significantly improve patient outcomes and reduce the global burden of stone disease.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"680-685"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12202690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-07-01Epub Date: 2025-05-26DOI: 10.1007/s00120-025-02598-2
Sebastian Grundl, Julian Nagler, Matthias Saar, Jennifer Kranz
{"title":"[Focus on boys' health: knowledge gaps, prevention deficits, and strategies to promote adolescent male wellbeing].","authors":"Sebastian Grundl, Julian Nagler, Matthias Saar, Jennifer Kranz","doi":"10.1007/s00120-025-02598-2","DOIUrl":"10.1007/s00120-025-02598-2","url":null,"abstract":"<p><p>Adolescent boys make significantly less use of sexual health services and educational resources than their female peers. This article analyses current knowledge, behavioral patterns, and prevention deficits in young males based on recent German studies. Major findings include limited awareness of sexually transmitted infections (STIs), low human papillomavirus (HPV) vaccination uptake, and insufficient understanding of testicular cancer risks. Although health check-ups (J1, J2) and school-based sex education are available, gender-specific barriers hinder effective access and implementation. This article discusses practical solutions, from establishing dedicated urology-based adolescent consultations (Jungensprechstunde) and implementing school-based HPV vaccination programs to using digital media for targeted communication. Physicians, especially urologists, play a crucial role as trusted health educators. Promoting early awareness, structural integration, and cross-sector collaboration is essential to improving health literacy, preventive behavior, equality, and long-term wellbeing among young men.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"636-644"},"PeriodicalIF":0.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-06-26DOI: 10.1007/s00120-025-02607-4
Christian Pfeiffer
{"title":"[Patient management in emergency and acute care: well-considered decision-making instead of actionism].","authors":"Christian Pfeiffer","doi":"10.1007/s00120-025-02607-4","DOIUrl":"https://doi.org/10.1007/s00120-025-02607-4","url":null,"abstract":"<p><p>Emergency and acute care in Germany is at a crossroads. Without a practical strategy tailored to regional circumstances, we run the risk of destabilizing healthcare provision in Germany in the long term. The care landscape in emergency medicine is highly complex and any reform must take this interplay into account. Another current problem is the increasing shortage of staff. In recent years, Bavaria has shown what future-oriented emergency care can look like. We must reform emergency care with caution and expertise. Politicians must not be guided by short-term promises of solutions, but must focus on proven, practical concepts.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}