UrologiePub Date : 2025-10-01Epub Date: 2025-09-17DOI: 10.1007/s00120-025-02676-5
Michael Meißner
{"title":"[Single-incision slings (mini-slings) as surgical treatment option for urinary incontinence in women].","authors":"Michael Meißner","doi":"10.1007/s00120-025-02676-5","DOIUrl":"10.1007/s00120-025-02676-5","url":null,"abstract":"","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"1079-1083"},"PeriodicalIF":0.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491083/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-10-01Epub Date: 2025-09-02DOI: 10.1007/s00120-025-02672-9
Yue Che, Alexandros Papachristofilou
{"title":"[Current developments in surgery and radiotherapy for the treatment of seminoma stage IIA/B].","authors":"Yue Che, Alexandros Papachristofilou","doi":"10.1007/s00120-025-02672-9","DOIUrl":"10.1007/s00120-025-02672-9","url":null,"abstract":"<p><strong>Background: </strong>Stage IIA/B seminoma is cured in over 90% of cases with standard therapies (polychemotherapy, large-volume radiotherapy). However, these treatments are associated with potential late toxicities.</p><p><strong>Materials and methods: </strong>This article addresses current developments from a urological-surgical and radiotherapeutic perspective in the treatment of stage IIA/B seminoma. Current study results are presented, and possible developments are outlined.</p><p><strong>Results and conclusion: </strong>Retroperitoneal lymphadenectomy (RLA) has the potential to offer a radiation- and chemotherapy-free treatment alternative. It was investigated in the recently published PRIMETEST, SEMS, and COTRIMS studies. Current clinical research focuses on the choice of template (unilateral vs. bilateral), the surgical approach (open vs. robotic), and the potential use of adjuvant chemotherapy after RLA (ongoing PRIMETEST II study). A combined, de-escalated chemoradiotherapy was evaluated in the SAKK 01/10 study and yielded very good results regarding recurrence-free survival and toxicity. Long-term results are still awaited, as are the results of the study SAKK 01/18.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"1018-1023"},"PeriodicalIF":0.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-10-01Epub Date: 2025-09-08DOI: 10.1007/s00120-025-02674-7
Margaretha A Skowron, Lisa Schneider, Evangelos Prokakis, Alexander Fichtner, Tim Nestler, Felix Bremmer, Daniel Nettersheim
{"title":"[New insights from basic research on testicular germ cell tumors and updated tumorigenesis].","authors":"Margaretha A Skowron, Lisa Schneider, Evangelos Prokakis, Alexander Fichtner, Tim Nestler, Felix Bremmer, Daniel Nettersheim","doi":"10.1007/s00120-025-02674-7","DOIUrl":"10.1007/s00120-025-02674-7","url":null,"abstract":"<p><p>Type II testicular germ cell tumors (GCT) are the most common malignant disease in young men, with a steadily increasing incidence. They originate from germ cell neoplasia in situ and are classified into seminomas (SE) and nonseminomas (NS). The NS subtype embryonal carcinoma (EC) exhibits stem cell-like characteristics and, thus, has the potential to differentiate into teratomas (TE) or extraembryonic tissues, such as yolk-sac tumors (YST) and choriocarcinomas (CC). Despite the success of cisplatin-based therapy, 10-15% of GCT patients do not (or no longer) respond to this treatment. Possible reasons include the development of cisplatin-induced resistance mechanisms as well as the plasticity of GCT, which can lead to the emergence of rare, therapy-resistant subtypes and, therefore, complicate treatment. In this review article, we present an updated perspective on the current model of GCT development and summarize new molecular insights regarding the emergence of occult/resistant YST populations within SE, the growing teratoma syndrome (GTS), and somatic-type malignancies (STM). These tumor subtypes are characterized by particularly aggressive and treatment-resistant behavior. However, little is currently known about these special GCT forms. Consequently, the heterogeneity and plasticity of these GCT components complicate treatment strategies. Therefore, we also describe promising biomarkers specific for the identification of YST, GTS, and STM to enhance current diagnostic approaches and, in particular, introduce new, alternative, and targeted therapeutic options for resistant YST components.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"1055-1063"},"PeriodicalIF":0.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-09-30DOI: 10.1007/s00120-025-02692-5
Moritz Goeldner
{"title":"[Resource-efficient use of single-use surgical textiles : A data-driven analysis of 213,000 surgeries from 2022].","authors":"Moritz Goeldner","doi":"10.1007/s00120-025-02692-5","DOIUrl":"https://doi.org/10.1007/s00120-025-02692-5","url":null,"abstract":"<p><p>Operating rooms are among the most resource-intensive areas of hospitals and generate significant amounts of waste and carbon emissions. Single-use surgical textiles contribute significantly to the ecological footprint of surgical procedures. As a surgical discipline, urology makes a significant contribution to the volume of surgical procedures. The goal of this study was to quantify the contribution of surgical textiles to overall resource consumption and to analyze the extent to which ecological and economic savings can be achieved through standardized use. The study used data on surgeries and consumption of surgical textiles from 25 hospitals (in four tier levels) that belong to a privately owned hospital chain operating throughout Germany. Actual consumption of surgical textiles in 2022 was compared against a target scenario based on predefined surgical standards. For each surgical standard, carbon emissions were calculated using a life cycle assessment and was then allocated to the respective surgeries. In 2022, 213,048 surgeries were performed in the 25 hospitals. A total of 352.7 tons of single-use surgical textiles were used, which corresponds to 1997 tons of CO<sub>2</sub> equivalents. Raw materials accounted for the largest share of emissions, while local transport made only a minor contribution. Consistent standardization could reduce CO<sub>2</sub> emissions by up to 8%. Particularly high savings potential was identified in orthopedic (up to 23.4%) and cardiology (up to 20.6%) clinics. The results show that a fraction of the resource consumption in the operating room is avoidable. Standardized use of single-use surgical textiles might offer both ecological and economic advantages.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-09-24DOI: 10.1007/s00120-025-02695-2
Kim-Victoria Seibert
{"title":"[Practicing the medical profession during pregnancy-Jointly find individual solutions].","authors":"Kim-Victoria Seibert","doi":"10.1007/s00120-025-02695-2","DOIUrl":"https://doi.org/10.1007/s00120-025-02695-2","url":null,"abstract":"","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145132086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-09-11DOI: 10.1007/s00120-025-02690-7
Alexander Reinisch-Liese, Juliane Liese, Frank Ulrich
{"title":"[Sustainable waste management in general surgical operations].","authors":"Alexander Reinisch-Liese, Juliane Liese, Frank Ulrich","doi":"10.1007/s00120-025-02690-7","DOIUrl":"https://doi.org/10.1007/s00120-025-02690-7","url":null,"abstract":"<p><strong>Background and objective of the study: </strong>Hospitals, especially surgical departments, are among the largest producers of waste in Germany. Data on waste management in the operating room (OR) are largely lacking. The aim of this study was to assess and discuss the possibilities of reducing waste and recovering recyclable materials in general surgery against the background of current practice.</p><p><strong>Methodology: </strong>Surgical departments throughout Germany were surveyed on waste management. First, the theoretical waste separation possibilities for laparoscopic appendectomy were determined. Subsequently, a simple system for the separation of recyclables was established and practically tested in 35 operations. These were compared with 35 appendectomies without separation.</p><p><strong>Results: </strong>Only 25.7% of hospitals perform waste separation. Theoretically, 20.7% of waste can be recycled, in practice up to 18.9%. Paper, cardboard and plastics, especially polyethylene terephthalate (PET) and high-density polyethylene (HDPE) were separated. This leads to a significant reduction in residual waste without extending the operation time.</p><p><strong>Discussion: </strong>Separation of recyclables can contribute to more sustainable waste management in the OR. High-value recyclables can be recycled and the residual waste mass can be significantly reduced. This is possible without special effort and does not delay the processes in the OR. The opportunities for this have hardly been used in Germany to date.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-09-02DOI: 10.1007/s00120-025-02670-x
Johannes Hermann Kilz, Karl-Friedrich Kowalewski
{"title":"[Prehabilitation and ERAS in the context of urosurgical procedures : New approaches to optimizing perioperative processes].","authors":"Johannes Hermann Kilz, Karl-Friedrich Kowalewski","doi":"10.1007/s00120-025-02670-x","DOIUrl":"https://doi.org/10.1007/s00120-025-02670-x","url":null,"abstract":"<p><p>As part of the improvement of perioperative standards the preoperative period before major urosurgical procedures is becoming increasingly more important. The concept of prehabilitation aims to raise the physical and mental capacities of patients to a higher level before the surgery in order to minimize postoperative decline. The intervention options include physical training, nutritional counselling, psychological support, patient education, optimization of sleep hygiene and the improvement of other preoperative parameters, such as existing anemia. It is important to recognize the existing deficits in each individual patient and to create a prehabilitation concept tailored to the patient. The concepts must also be cost-efficient and capable of being integrated into everyday clinical practice.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-09-02DOI: 10.1007/s00120-025-02683-6
Sven Trommer, Peter Middel, Benno Kretzschmar, Heiko Wunderlich
{"title":"[Rare cause of genital edema in a child].","authors":"Sven Trommer, Peter Middel, Benno Kretzschmar, Heiko Wunderlich","doi":"10.1007/s00120-025-02683-6","DOIUrl":"https://doi.org/10.1007/s00120-025-02683-6","url":null,"abstract":"","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-09-01DOI: 10.1007/s00120-025-02667-6
{"title":"BvDU Kurz notiert.","authors":"","doi":"10.1007/s00120-025-02667-6","DOIUrl":"https://doi.org/10.1007/s00120-025-02667-6","url":null,"abstract":"","PeriodicalId":29782,"journal":{"name":"Urologie","volume":"64 9","pages":"996"},"PeriodicalIF":0.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}