[Retroperitoneal lymphadenectomy (RPLND) for the treatment of testicular germ cell tumors-open or robotic? Pro open surgery : RPLND in the management of testis cancer].

IF 0.4 4区 医学 Q4 UROLOGY & NEPHROLOGY
Urologie Pub Date : 2025-10-01 Epub Date: 2025-09-11 DOI:10.1007/s00120-025-02673-8
Axel Heidenreich, David Pfister
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引用次数: 0

Abstract

Retroperitoneal lymphadenectomy (RPLND) represents an established surgical treatment option for patients with testicular germ cell tumors and might be performed at various clinical stages depending on individual risk factors. Typically, RPLND is performed via a trans- or extraperitoneal open approach with dissection of a unilateral or bilateral template. Since robot-assisted approaches have been established in uro-oncological surgery, the question arises whether there is already an established indication to perform robot-assisted RPLNDs (R-RPLND). International guidelines recommend that such a surgical procedure should only be performed for selected patients in testicular cancer referral centers by highly experienced testicular cancer surgeons. We reviewed the recently published data of R‑RPLND and we conclude that R‑RPLND is technically feasible and that it can be performed with equal complication rates if done in an expert center. However, there is no benefit in terms of oncological and functional outcome. Based on the results of multicenter trials and meta-analyses, antegrade ejaculation is only preserved in 65-70% of the patients, which is inferior to open surgery done in expert centers. Duration of surgery is significantly longer compared to open surgery. Oncological outcome following R‑RPLND is difficult to validate due to the short follow-up intervals and the selection of patients. Comparison of postchemotherapeutic R‑RPLND with open surgery is also hampered due to highly selected patients with only small residual masses and short follow-up periods. In summary, R‑RPLND should only be established in testicular cancer expert centers. Currently, we perform R‑RPLND especially for marker negative clinical stage IIA/B with lymph node metastases with a size of less or equal to 3 cm.

腹膜后淋巴结切除术(RPLND)治疗睾丸生殖细胞肿瘤-开放还是机器人?开放性手术:RPLND在睾丸癌治疗中的应用。
腹膜后淋巴结切除术(RPLND)是睾丸生殖细胞肿瘤患者的一种成熟的手术治疗选择,可根据个体危险因素在不同的临床阶段进行。典型情况下,RPLND通过经或腹腔外开放入路进行,同时剥离单侧或双侧模板。由于机器人辅助方法已经在泌尿肿瘤手术中建立,问题是是否已经有一个确定的适应症来执行机器人辅助rplnd (R-RPLND)。国际指南建议,这种手术只能由经验丰富的睾丸癌外科医生在睾丸癌转诊中心对选定的患者进行。我们回顾了最近发表的R - RPLND的数据,我们得出结论,R - RPLND在技术上是可行的,如果在专家中心进行,并发症发生率相同。然而,就肿瘤和功能结果而言,没有任何益处。根据多中心试验和荟萃分析的结果,只有65-70%的患者保留了顺行性射精,这比在专家中心进行的开放手术要差。与开放手术相比,手术时间明显更长。R - RPLND术后的肿瘤预后由于随访时间短和患者的选择而难以验证。化疗后R - RPLND与开放手术的比较也受到阻碍,因为高度选择的患者只有较小的残余肿块和较短的随访时间。总之,R - RPLND只应在睾丸癌专家中心建立。目前,我们特别针对标志物阴性的临床IIA/B期淋巴结转移小于或等于3 cm的患者实施R - RPLND。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Urologie
Urologie UROLOGY & NEPHROLOGY-
CiteScore
1.00
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0.00%
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