[Pediatric testicular tumors].

IF 0.5 4区医学 Q4 UROLOGY & NEPHROLOGY

Urologie Pub Date : 2025-05-09 DOI:10.1007/s00120-025-02601-w

Pia Paffenholz

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Abstract

Background: Testicular tumors are rare in childhood but differ significantly from adult forms in terms of etiology, histology, and prognosis. Early diagnosis and appropriate treatment are crucial for the prognosis and quality of life of affected children.

Objective: The aim of this article is to provide an overview of the etiology, classification, clinical presentation, diagnostic tests, and treatment of pediatric testicular tumors.

Materials and methods: This article is based on an analysis of current literature.

Results: Pediatric testicular tumors are benign in 60-75% of cases, most commonly teratomas or Leydig cell tumors. Malignant tumors such as yolk sac tumors are rare and show low metastatic potential. Diagnostics include ultrasound, tumor markers (AFP, hCG, LDH), and imaging (MRI, CT). Treatment consists of organ-sparing surgery in suspected benign cases and orchiectomy in malignant cases. Chemotherapy is reserved for metastatic tumors. In localized stage I disease, surveillance is often sufficient.

Conclusion: Pediatric germ cell tumors differ from adult testicular tumors in terms of incidence, malignancy, and histology. Treatment decisions should always be made within an interdisciplinary framework.

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[小儿睾丸肿瘤]。

背景：儿童睾丸肿瘤很少见，但在病因、组织学和预后方面与成人睾丸肿瘤有很大不同。早期诊断和适当治疗对受影响儿童的预后和生活质量至关重要。目的：本文的目的是提供的病因，分类，临床表现，诊断检查和治疗儿科睾丸肿瘤的概述。材料和方法：本文是在对现有文献进行分析的基础上进行的。结果：60-75%的儿童睾丸肿瘤为良性，以畸胎瘤或间质细胞瘤最为常见。恶性肿瘤如卵黄囊肿瘤是罕见的，具有低转移潜力。诊断包括超声、肿瘤标志物（AFP、hCG、LDH）和影像学（MRI、CT）。治疗包括怀疑良性病例的保留器官手术和恶性病例的睾丸切除术。化疗只用于转移性肿瘤。在局部I期疾病中，监测通常就足够了。结论：儿童生殖细胞肿瘤在发病率、恶性程度和组织学上与成人睾丸肿瘤不同。治疗决策应始终在跨学科框架内作出。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Urologie UROLOGY & NEPHROLOGY-

CiteScore

1.00

自引率

0.00%

发文量