{"title":"[A rapid review: quality of life in adult allogeneic kidney transplantation in the last five years : What can we learn?]","authors":"Lujza Brunaiova, Stefanie Cermak, Lukas Koneval, Beat Roth, Laila Schneidewind","doi":"10.1007/s00120-024-02497-y","DOIUrl":"10.1007/s00120-024-02497-y","url":null,"abstract":"<p><strong>Background: </strong>Recent studies have also shown that clinical monitoring of quality of life (HRQoL) helps to recognize kidney transplant failure at an early stage.</p><p><strong>Objectives: </strong>Given the potential of improving HRQoL for the long-term outcomes of kidney transplantation, we conducted a rapid review of the last 5 years of quality of life evaluation after adult allogeneic kidney transplantation.</p><p><strong>Materials and methods: </strong>A rapid evidence analysis was carried out using a literature search in MEDLINE in the period 2019-2024.</p><p><strong>Results: </strong>The primary literature search yielded 554 hits, and ultimately only 12 cohort studies could be included, of which 2 were retrospective and 10 prospective cohort studies. Kidney transplant patients have better HRQoL than patients with end-stage renal disease. HRQoL is influenced by physical, psychological, and social factors. Further improvement of HRQoL or the primary influencing factors has the potential to further enhance the outcomes of kidney transplantation. However, studies to identify suitable interventions are lacking. Interesting factors to be influenced could be, for example, respiratory symptoms and support for professional reintegration.</p><p><strong>Conclusion: </strong>Future studies should focus on the identification of adequate interventions to further improve HRQoL in kidney transplant recipients.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"358-368"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11985567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-04-01Epub Date: 2025-03-10DOI: 10.1007/s00120-025-02550-4
Jonas Herrmann, Christopher Netsch
{"title":"[Conflicts of interest in scientific publications and possible consequences : A critical analysis using the example of benign prostatic hyperplasia (BPH)].","authors":"Jonas Herrmann, Christopher Netsch","doi":"10.1007/s00120-025-02550-4","DOIUrl":"10.1007/s00120-025-02550-4","url":null,"abstract":"<p><p>Technological advancements in endourology rely on close collaboration between medical expertise and industrial research. While this symbiosis is essential for medical progress, it also raises potential conflicts of interest. Using the treatment of benign prostatic hyperplasia (BPH) as an example, this study examines various mechanisms through which industry influences scientific evidence. These include selective study design, industry-sponsored educational events, and direct financial ties between industry and medical professionals. Case studies of Aquablation (ProCePT BioRobotics, San Jose CA, USA), Rezum (Boston Scientific, Marborough, MA, USA), and UroLift® (UroLift, Pleasanton, CA, USA) illustrate how methodological peculiarities in study designs and selective endpoint choices can impact the quality of evidence. The analysis underscores the need to balance technological innovation with the preservation of scientific independence. Proposed solutions include strengthening independent research funding, systematically incorporating patient preferences, and ensuring structured follow-up of long-term outcomes.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"352-357"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-04-01Epub Date: 2025-03-11DOI: 10.1007/s00120-025-02551-3
Thomas Enzmann, Julia Buchinski, Oliver Pramann
{"title":"[We are obligated to exercise due diligence-but what does this look like in practice?]","authors":"Thomas Enzmann, Julia Buchinski, Oliver Pramann","doi":"10.1007/s00120-025-02551-3","DOIUrl":"10.1007/s00120-025-02551-3","url":null,"abstract":"<p><p>Expert reports analyze medical malpractice in urology based on selected case studies and assess their medical and legal implications. Common sources of error include noncompliance with clinical guidelines, inadequate patient information, insufficient diagnostics, and a lack of interdisciplinary coordination. The cases include, among others, incorrect biopsy techniques, delayed stroke diagnoses, failure to communicate pathological findings, and problematic coercive measures in pediatric patients. The legal assessments highlight the importance of thorough documentation and effective patient communication in mitigating liability risks. In several cases, diagnostic errors result in a reversal of the burden of proof in favor of the patient. The expert report emphasizes the necessity of a structured, evidence-based, and interdisciplinary approach to minimize treatment errors and their consequences.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"344-351"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-04-01Epub Date: 2025-02-20DOI: 10.1007/s00120-025-02523-7
Christian Thomas, Martin Baunacke
{"title":"[Things worth knowing about drug-based osteoprotection in uro-oncology].","authors":"Christian Thomas, Martin Baunacke","doi":"10.1007/s00120-025-02523-7","DOIUrl":"10.1007/s00120-025-02523-7","url":null,"abstract":"<p><p>Bone metastases in uro-oncology bear a high risk for bone-related complications (skeletal-related events, SRE). The presence of SRE is associated with an increased risk for death, which is markedly increased in the presence of pathological fractures. Prostate cancer and renal cell carcinoma in particular result in bone metastases in advanced stages. The SREs also represent an economic problem and lead to nearly double the costs of treatment. Zoledronic acid and denosumab are both approved osteoprotective drugs for the prevention or delay of SRE in metastatic disease. Interestingly, zoledronic acid does not reduce the incidence of SRE in hormone-sensitive prostate cancer. The dosage and administration of both drugs differ in the treatment of bone metastases and treatment or prophylaxis of osteoporosis. Long-term treatment with one of these two drugs is associated with the risk of development of medication-related osteonecrosis of the jaw (MRONJ). Routine controls of the oral cavity before and during treatment are mandatory in these patients.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"380-386"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-04-01DOI: 10.1007/s00120-025-02562-0
{"title":"BvDU Kurz notiert.","authors":"","doi":"10.1007/s00120-025-02562-0","DOIUrl":"https://doi.org/10.1007/s00120-025-02562-0","url":null,"abstract":"","PeriodicalId":29782,"journal":{"name":"Urologie","volume":"64 4","pages":"394"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UrologiePub Date : 2025-04-01Epub Date: 2025-02-21DOI: 10.1007/s00120-025-02536-2
H Schülke, C Süfke, A J Gross
{"title":"[Ensuring the patient does not become an adversary-a \"how to\" guide for handling allegations of medical malpractice].","authors":"H Schülke, C Süfke, A J Gross","doi":"10.1007/s00120-025-02536-2","DOIUrl":"10.1007/s00120-025-02536-2","url":null,"abstract":"<p><p>If there is an allegation of medical malpractice, it significantly strains the physician-patient relationship. To avoid a conflict-ridden dispute with the patient, it is crucial to internally analyze the course of treatment. The legal focus is on whether the patient's complaints are attributable to medical misconduct or if they stem from an inevitable complication that is part of the treatment's risk spectrum. Additionally, the insights gained from the internal review help establish operating procedures and responsibilities. Open communication promotes the recognition of any misconduct and contributes to its prevention in the future. If medical malpractice is suspected, the competent departments should be informed early, and the documentation of the hospital treatment should be checked for completeness and plausibility. Moreover, a transparent explanation of the treatment course-regardless of fault-alleviates patient's fears and concerns, which can help to avoid potential conflict situations.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"335-343"},"PeriodicalIF":0.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}